Zhou Chen, PhD
Postdoctoral Scholar
Cardiovascular Research Inst
School of Medicine

Publications (5)

Top publication keywords:
MyocardiumBatrachotoxinsSaxitoxinMembrane ProteinsLigandsGuanidineNeurotoxinsCalcium ChannelsBinding SitesEndoplasmic ReticulumPoisonsRana catesbeianaCryoelectron MicroscopyCalcium Channels, L-TypeCarrier Proteins

• Expression, purification, and characterization of anuran saxiphilins using thermofluor, fluorescence polarization, and isothermal titration calorimetry.
  STAR protocols 2023 Chen Z, Zakrzewska S, Hajare HS, Du Bois J, Minor DL
• EMC chaperone-CaV structure reveals an ion channel assembly intermediate.
  Nature 2023 Chen Z, Mondal A, Abderemane-Ali F, Jang S, Niranjan S, Montaño JL, Zaro BW, Minor DL
• Structural basis for CaVα2δ:gabapentin binding.
  Nature structural & molecular biology 2023 Chen Z, Mondal A, Minor DL
• Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Chen Z, Zakrzewska S, Hajare HS, Alvarez-Buylla A, Abderemane-Ali F, Bogan M, Ramirez D, O'Connell LA, Du Bois J, Minor DL
• Evidence that toxin resistance in poison birds and frogs is not rooted in sodium channel mutations and may rely on "toxin sponge" proteins.
  The Journal of general physiology 2021 Abderemane-Ali F, Rossen ND, Kobiela ME, Craig RA, Garrison CE, Chen Z, Colleran CM, O'Connell LA, Du Bois J, Dumbacher JP, Minor DL