Yu-Ting Chou, PhD
Associate Specialist
Medicine
School of Medicine

Publications (9)

Top publication keywords:
Extracellular Signal-Regulated MAP Kinasesras ProteinsCell Line, TumorZebrafishAldose-Ketose IsomerasesProtein Tyrosine Phosphatase, Non-Receptor Type 11Liver Neoplasms, ExperimentalWnt-5a ProteinFactor XCytoplasmic GranulesNeoplasmsReceptor Tyrosine Kinase-like Orphan Receptorsbeta CateninAnimals, Genetically ModifiedEnzyme Inhibitors

• Suppression of Ribose-5-Phosphate Isomerase a Induces ROS to Activate Autophagy, Apoptosis, and Cellular Senescence in Lung Cancer.
  International journal of molecular sciences 2022 Nieh YC, Chou YT, Chou YT, Wang CY, Lin SX, Ciou SC, Yuh CH, Wang HD
• Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer.
  The Journal of clinical investigation 2022 Nanjo S, Wu W, Karachaliou N, Blakely CM, Suzuki J, Chou YT, Ali SM, Kerr DL, Olivas VR, Shue J, Rotow J, Mayekar MK, Haderk F, Chatterjee N, Urisman A, Yeo JC, Skanderup AJ, Tan AC, Tam WL, Arrieta O…
• Inhibition of SHP2 as an approach to block RAS-driven cancers.
  Advances in cancer research 2021 Chou YT, Bivona TG
• Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules.
  Cell 2021 Tulpule A, Guan J, Neel DS, Allegakoen HR, Lin YP, Brown D, Chou YT, Heslin A, Chatterjee N, Perati S, Menon S, Nguyen TA, Debnath J, Ramirez AD, Shi X, Yang B, Feng S, Makhija S, Huang B, Bivona TG
• A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis.
  eLife 2020 Zhang K, Yao E, Lin C, Chou YT, Wong J, Li J, Wolters PJ, Chuang PT

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• Ribose-5-phosphate isomerase A overexpression promotes liver cancer development in transgenic zebrafish via activation of ERK and β-catenin pathways.
  Carcinogenesis 2019 Chou YT, Chen LY, Tsai SL, Tu HC, Lu JW, Ciou SC, Wang HD, Yuh CH
• Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domain.
  PLoS biology 2018 Chou YT, Jiang JK, Yang MH, Lu JW, Lin HK, Wang HD, Yuh CH
• Up-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis.
  Hepatology communications 2017 Tu HC, Hsiao YC, Yang WY, Tsai SL, Lin HK, Liao CY, Lu JW, Chou YT, Wang HD, Yuh CH
• Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling.
  International journal of cancer 2014 Ciou SC, Chou YT, Liu YL, Nieh YC, Lu JW, Huang SF, Chou YT, Cheng LH, Lo JF, Chen MJ, Yang MC, Yuh CH, Wang HD