Young-Wook Jun, PhD
Professor
Otolaryngology
School of Medicine
Young-wook Jun attended Yonsei University in Korea, where he received a Bachelor's degree in Chemistry in 1999. He did his graduate studies at the Korea Advances Institute of Science, where he broadly investigated the chemistry of nanocrystals. He carried out postdoctoral studies with Prof.
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Paul Alivisatos at the University of California, Berkeley when he first began research related to microscopy- and nanotechnology-based biophysical tools. In 2010, he joined the faculty of UCSF, where he is presently a professor. He received the Endowed Hemming Fellowship, Sandler-UCSF New Frontier Research Award, The World Most-Influential Scientific Mind.
Websites
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- Jun Lab (junlab.ucsf.edu)
Grants and Projects
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- Spatiotemporal interrogation of molecular mechanobiololgy at the cell-cell interface with nanotechnology tools, NIH, 2020-2025
- Notch1 and APP signaling in cerebral microvascular dysfunction, NIH, 2021-2023
- Nanomodules for interrogating chemical, spatial, and mechanical dynamics of cell surface receptors, NIH, 2017-2021
- In situ Investigation of dynamic protein-protein interactions in live cells via Magnetic Co-concentration (MCoC), NIH, 2018-2019
- Spatiotemporal Control of Dynamic Notch Signaling with Subcellular Resolution, NIH, 2014-2019
- Interrogation of mechanotransduction ion channels via nanoruler force microscopy and mechanogenetic nanomodules, NIH, 2017-2019
- Spatial Mutation of Membrane Protein Assembly Dynamics Using Nano-Actuators, NIH, 2014-2017
- Small, modular, and monovalent Quantum Dots for single molecule imaging of Notch, NIH, 2014-2016
- Single Molecule Imaging of Guided Axonal Development using Plasmon Nanorulers, NIH, 2012-2014
Publications (54)
Top publication keywords:
SNARE ProteinsCadherinsCaspase 3NanostructuresNanotechnologyFerrous CompoundsMolecular Probe TechniquesAmyloid Precursor Protein SecretasesGenetic TechniquesQuantum DotsMetal NanoparticlesNanoparticlesActinsMagnetite NanoparticlesMagnetics
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Hydrogel Magnetomechanical Actuator Nanoparticles for Wireless Remote Control of Mechanosignaling In Vivo.
Nano letters 2023 Jeong S, Shin W, Park M, Lee JU, Lim Y, Noh K, Lee JH, Jun YW, Kwak M, Cheon J -
Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.
Nature cell biology 2022 Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, Kutys ML, Seo D, Kim HH, Kim YH, Cheon J, Gartner ZJ, … -
A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time.
Cell 2016 Seo D, Southard KM, Kim JW, Lee HJ, Farlow J, Lee JU, Litt DB, Haas T, Alivisatos AP, Cheon J, Gartner ZJ, Jun YW -
Formation of targeted monovalent quantum dots by steric exclusion.
Nature methods 2013 Farlow J, Seo D, Broaders KE, Taylor MJ, Gartner ZJ, Jun YW -
Yeast lunapark regulates the formation of trans-Sey1p complexes for homotypic ER membrane fusion.
iScience 2023 Jang E, Lee M, Yoon SY, Lee SS, Park J, Jin MS, Eom SH, Lee C, Jun Y
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Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion.
The Journal of cell biology 2023 White MJ, Jacobs KA, Singh T, Mayo LN, Lin A, Chen CS, Jun YW, Kutys ML -
Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen.
ACS applied materials & interfaces 2021 Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR -
Small, Clickable, and Monovalent Magnetofluorescent Nanoparticles Enable Mechanogenetic Regulation of Receptors in a Crowded Live-Cell Microenvironment.
Nano letters 2019 Kwak M, Gu W, Jeong H, Lee H, Lee JU, An M, Kim YH, Lee JH, Cheon J, Jun YW -
Magnetic Nanotweezers for Interrogating Biological Processes in Space and Time.
Accounts of chemical research 2018 Kim JW, Jeong HK, Southard KM, Jun YW, Cheon J -
Single-cell mechanogenetics using monovalent magnetoplasmonic nanoparticles.
Nature protocols 2017 Kim JW, Seo D, Lee JU, Southard KM, Lim Y, Kim D, Gartner ZJ, Jun YW, Cheon J -
Monovalent plasmonic nanoparticles for biological applications
Proceedings of SPIE--the International Society for Optical Engineering 2016 Daeha Seo, Hyunjung Lee, Jung-uk Lee, Thomas Haas, Young-wook Jun -
In Vitro Capture of Small Ferrous Particles with a Magnetic Filtration Device Designed for Intravascular Use with Intraarterial Chemotherapy: Proof-of-Concept Study.
Journal of vascular and interventional radiology : JVIR 2015 Mabray MC, Lillaney P, Sze CH, Losey AD, Yang J, Kondapavulur S, Liu D, Saeed M, Patel A, Cooke D, Jun YW, El-Sayed I, Wilson M, Hetts SW -
SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiae.
The Journal of cell biology 2015 Lee M, Ko YJ, Moon Y, Han M, Kim HW, Lee SH, Kang K, Jun Y -
Production and targeting of monovalent quantum dots.
Journal of visualized experiments : JoVE 2014 Seo D, Farlow J, Southard K, Jun YW, Gartner ZJ -
Sensitive and selective plasmon ruler nanosensors for monitoring the apoptotic drug response in leukemia.
ACS nano 2014 Tajon CA, Seo D, Asmussen J, Shah N, Jun YW, Craik CS -
Single-molecule sensing of caspase activation in live cells via plasmon coupling nanotechnology.
Methods in enzymology 2014 Tajon C, Jun YW, Craik CS -
MEK-dependent negative feedback underlies BCR-ABL-mediated oncogene addiction.
Cancer discovery 2013 Asmussen J, Lasater EA, Tajon C, Oses-Prieto J, Jun YW, Taylor BS, Burlingame A, Craik CS, Shah NP -
Biotite dissolution in brine at varied temperatures and CO2 pressures: its activation energy and potential CO2 intercalation.
Langmuir : the ACS journal of surfaces and colloids 2012 Hu Y, Jun YS -
Coupling of optical resonances in a compositionally asymmetric plasmonic nanoparticle dimer.
Nano letters 2010 Sheikholeslami S, Jun YW, Jain PK, Alivisatos AP -
Hetero-epitaxial anion exchange yields single-crystalline hollow nanoparticles.
Journal of the American Chemical Society 2009 Park J, Zheng H, Jun YW, Alivisatos AP -
Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation at the single-molecule level.
Proceedings of the National Academy of Sciences of the United States of America 2009 Jun YW, Sheikholeslami S, Hostetter DR, Tajon C, Craik CS, Alivisatos AP -
Observation of single colloidal platinum nanocrystal growth trajectories.
Science (New York, N.Y.) 2009 Zheng H, Smith RK, Jun YW, Kisielowski C, Dahmen U, Alivisatos AP -
Nanoscaling laws of magnetic nanoparticles and their applicabilities in biomedical sciences.
Accounts of chemical research 2008 Jun YW, Seo JW, Cheon J -
Chemical design of nanoparticle probes for high-performance magnetic resonance imaging.
Angewandte Chemie (International ed. in English) 2008 Jun YW, Lee JH, Cheon J -
Highly crystalline anisotropic superstructures via magnetic field induced nanoparticle assembly.
Chemical communications (Cambridge, England) 2007 Park JI, Jun YW, Choi JS, Cheon J -
Hybrid Nanoparticles for Magnetic Resonance Imaging of Target-Specific Viral Gene Delivery
Advanced Materials 2007 Yong-Min Huh, Eun-Sook Lee, Jae-Hyun Lee, Young-wook Jun, Pyung-Hwan Kim, Chae-Ok Yun, Joo-Hang Kim, Jin-Suck Suh, Jinwoo Cheon -
Magnetic nanoparticle assisted molecular MR imaging.
Advances in experimental medicine and biology 2007 Jun YW, Jang JT, Cheon J -
Two-dimensional nanosheet crystals.
Angewandte Chemie (International ed. in English) 2007 Seo JW, Jun YW, Park SW, Nah H, Moon T, Park B, Kim JG, Kim YJ, Cheon J -
Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging.
Nature medicine 2006 Lee JH, Huh YM, Jun YW, Seo JW, Jang JT, Song HT, Kim S, Cho EJ, Yoon HG, Suh JS, Cheon J -
Biocompatible heterostructured nanoparticles for multimodal biological detection.
Journal of the American Chemical Society 2006 Choi JS, Jun YW, Yeon SI, Kim HC, Shin JS, Cheon J -
Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma.
Angewandte Chemie (International ed. in English) 2006 Lee JH, Jun YW, Yeon SI, Shin JS, Cheon J -
Heterostructured magnetic nanoparticles: their versatility and high performance capabilities.
Chemical communications (Cambridge, England) 2006 Jun YW, Choi JS, Cheon J -
Shape control of semiconductor and metal oxide nanocrystals through nonhydrolytic colloidal routes.
Angewandte Chemie (International ed. in English) 2006 Jun YW, Choi JS, Cheon J -
Magnetic superlattices and their nanoscale phase transition effects.
Proceedings of the National Academy of Sciences of the United States of America 2006 Cheon J, Park JI, Choi JS, Jun YW, Kim S, Kim MG, Kim YM, Kim YJ -
Selective catalytic activity of ball-shaped Pd@MCM-48 nanocatalysts.
Chemical communications (Cambridge, England) 2006 Lee HY, Ryu S, Kang H, Jun YW, Cheon J -
The concept of delayed nucleation in nanocrystal growth demonstrated for the case of iron oxide nanodisks.
Journal of the American Chemical Society 2006 Casula MF, Jun YW, Zaziski DJ, Chan EM, Corrias A, Alivisatos AP -
In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals.
Journal of the American Chemical Society 2005 Huh YM, Jun YW, Song HT, Kim S, Choi JS, Lee JH, Yoon S, Kim KS, Shin JS, Suh JS, Cheon J -
Symmetry-controlled colloidal nanocrystals: nonhydrolytic chemical synthesis and shape determining parameters.
The journal of physical chemistry. B 2005 Jun YW, Lee JH, Choi JS, Cheon J -
Surface modulation of magnetic nanocrystals in the development of highly efficient magnetic resonance probes for intracellular labeling.
Journal of the American Chemical Society 2005 Song HT, Choi JS, Huh YM, Kim S, Jun YW, Suh JS, Cheon J -
Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging.
Journal of the American Chemical Society 2005 Jun YW, Huh YM, Choi JS, Lee JH, Song HT, Kim S, Yoon S, Kim KS, Shin JS, Suh JS, Cheon J -
In situ one-pot synthesis of 1-dimensional transition metal oxide nanocrystals.
The journal of physical chemistry. B 2005 Seo JW, Jun YW, Ko SJ, Cheon J -
Recent advances in the shape control of inorganic nano-building blocks
Coordination Chemistry Reviews 2005 Young-wook Jun, Jung-wook Seo, Sang Jun Oh, Jinwoo Cheon -
Spontaneous one dimensional arrangement of spherical Au nanoparticles with liquid crystal ligands.
Chemical communications (Cambridge, England) 2004 In I, Jun YW, Kim YJ, Kim SY -
Thiacrownether-mediated Size-controlled Assembly of Gold Nanoparticles
Chemistry Letters 2004 Insik In, Young-Wook Jun, Yun Jun Kim, Sang Youl Kim -
Characterization of superparamagnetic "core-shell" nanoparticles and monitoring their anisotropic phase transition to ferromagnetic "solid solution" nanoalloys.
Journal of the American Chemical Society 2004 Park JI, Kim MG, Jun YW, Lee JS, Lee WR, Cheon J -
Surfactant-assisted elimination of a high energy facet as a means of controlling the shapes of TiO2 nanocrystals.
Journal of the American Chemical Society 2003 Jun YW, Casula MF, Sim JH, Kim SY, Cheon J, Alivisatos AP -
Sterically induced shape and crystalline phase control of GaP nanocrystals.
Journal of the American Chemical Society 2002 Kim YH, Jun YW, Jun BH, Lee SM, Cheon J -
Single-crystalline star-shaped nanocrystals and their evolution: programming the geometry of nano-building blocks.
Journal of the American Chemical Society 2002 Lee SM, Jun YW, Cho SN, Cheon J -
Superlattice and magnetism directed by the size and shape of nanocrystals.
Chemphyschem : a European journal of chemical physics and physical chemistry 2002 Park JI, Kang NJ, Jun YW, Oh SJ, Ri HC, Cheon J -
Architectural control of magnetic semiconductor nanocrystals.
Journal of the American Chemical Society 2002 Jun YW, Jung YY, Cheon J -
Controlled synthesis of multi-armed CdS nanorod architectures using monosurfactant system.
Journal of the American Chemical Society 2001 Jun YW, Lee SM, Kang NJ, Cheon J -
Size and shape controlled ZnTe nanocrystals with quantum confinement effect
Chemical Communications 2000 Young-wook Jun, Chang-Shik Choi, Jinwoo Cheon -
Synthesis of Porous Palladium Superlattice Nanoballs and Nanowires
Chemistry of Materials 2000 Hongkyu Kang, Young-wook Jun, Jong-Il Park, Kyung-Bok Lee, and Jinwoo Cheon -
One-step synthesis of size tuned zinc selenide quantum dots via a temperature controlled molecular precursor approach
Chemical Communications 2000 Young-wook Jun, Ja-Eung Koo, Jinwoo Cheon