Yann Ehinger, PhD
Asst Professional Researcher
Neurology
School of Medicine

Publications (23)

Top publication keywords:
Methyl-CpG-Binding Protein 2GlycolysisEthanolNucleus AccumbensCorpus StriatumAlcohol DrinkingNeurosecretionNeostriatumProtein BiosynthesisMicroRNAsRett SyndromeBrain-Derived Neurotrophic FactorHuntingtin ProteinMechanistic Target of Rapamycin Complex 1Alcoholism

• Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Male Mice Consuming Alcohol Attenuates Glycolysis.
  Nature communications 2025 Ehinger Y, Laguesse S, Phamluong K, Salvi A, Sei YJ, Hoisington ZW, Soneja D, Gunasekaran S, Nakamura K, Ron D
• Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Mice Consuming Alcohol Attenuates Glycolysis.
  bioRxiv : the preprint server for biology 2025 Ehinger Y, Laguesse S, Phamluong K, Salvi A, Sei YJ, Hoisington ZW, Soneja D, Gunasekaran S, Nakamura K, Ron D
• BDNF in Ventrolateral Orbitofrontal Cortex to Dorsolateral Striatum Circuit Moderates Alcohol Consumption and Gates Alcohol Habit.
  bioRxiv : the preprint server for biology 2025 Gunasekaran S, Moffat JJ, Epstein JD, Phamluong K, Ehinger Y, Ron D
• Prosapip1 in the dorsal hippocampus mediates synaptic protein composition, long-term potentiation, and spatial memory.
  bioRxiv : the preprint server for biology 2025 Hoisington ZW, Gangal H, Phamluong K, Shukla C, Ehinger Y, Moffat JJ, Homanics GE, Wang J, Ron D
• The Small G-Protein Rac1 in the Dorsomedial Striatum Promotes Alcohol-Dependent Structural Plasticity and Goal-Directed Learning in Mice.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Hoisington ZW, Salvi A, Laguesse S, Ehinger Y, Shukla C, Phamluong K, Ron D

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• Sex Differences In The Interaction Between Alcohol And mTORC1.
  bioRxiv : the preprint server for biology 2024 Ehinger Y, Phamluong K, Ron D
• The small G-protein Rac1 in the dorsomedial striatum promotes alcohol-dependent structural plasticity and goal-directed learning in mice.
  bioRxiv : the preprint server for biology 2024 Hoisington ZW, Salvi A, Laguesse S, Ehinger Y, Shukla C, Phamluong K, Ron D
• Identification of Novel BDNF-Specific Corticostriatal Circuitries.
  eNeuro 2023 Ehinger Y, Soneja D, Phamluong K, Salvi A, Ron D
• The BDNF Val68Met polymorphism causes a sex specific alcohol preference over social interaction and also acute tolerance to the anxiolytic effects of alcohol, a phenotype driven by malfunction of BDNF in the ventral hippocampus of male mice.
  Psychopharmacology 2023 Moffat JJ, Sakhai SA, Hoisington ZW, Ehinger Y, Ron D
• State-of-the-art therapies for Rett syndrome.
  Developmental medicine and child neurology 2022 Panayotis N, Ehinger Y, Felix MS, Roux JC
• Correction: mTORC1 in the orbitofrontal cortex promotes habitual alcohol seeking.
  eLife 2022 Morisot N, Phamluong K, Ehinger Y, Berger AL, Moffat JJ, Ron D
• Ultrasound-Mediated Blood-Brain Barrier Opening Improves Whole Brain Gene Delivery in Mice.
  Pharmaceutics 2021 Felix MS, Borloz E, Metwally K, Dauba A, Larrat B, Matagne V, Ehinger Y, Villard L, Novell A, Mensah S, Roux JC
• Brain-specific inhibition of mTORC1 eliminates side effects resulting from mTORC1 blockade in the periphery and reduces alcohol intake in mice.
  Nature communications 2021 Ehinger Y, Zhang Z, Phamluong K, Soneja D, Shokat KM, Ron D
• PI3-Kinase p110β in Cortical Circuitries and Cocaine-Dependent Maladaptative Behaviors.
  Biological psychiatry 2021 Ehinger Y
• Analysis of Astroglial Secretomic Profile in the Mecp2-Deficient Male Mouse Model of Rett Syndrome.
  International journal of molecular sciences 2021 Ehinger Y, Matagne V, Cunin V, Borloz E, Seve M, Bourgoin-Voillard S, Borges-Correia A, Villard L, Roux JC
• Severe offtarget effects following intravenous delivery of AAV9-MECP2 in a female mouse model of Rett syndrome.
  Neurobiology of disease 2020 Matagne V, Borloz E, Ehinger Y, Saidi L, Villard L, Roux JC
• A non-hallucinogenic psychedelic analogue with therapeutic potential.
  Nature 2020 Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia …
• cAMP-Fyn signaling in the dorsomedial striatum direct pathway drives excessive alcohol use.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2020 Ehinger Y, Morisot N, Phamluong K, Sakhai SA, Soneja D, Adrover MF, Alvarez VA, Ron D
• Differential correlation of serum BDNF and microRNA content in rats with rapid or late onset of heavy alcohol use.
  Addiction biology 2020 Ehinger Y, Phamluong K, Darevesky D, Welman M, Moffat JJ, Sakhai SA, Whiteley EL, Berger AL, Laguesse S, Farokhnia M, Leggio L, Lordkipanidzé M, Ron D
• Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice.
  EMBO molecular medicine 2020 Ehinger Y, Bruyère J, Panayotis N, Abada YS, Borloz E, Matagne V, Scaramuzzino C, Vitet H, Delatour B, Saidi L, Villard L, Saudou F, Roux JC
• mTORC1 in the orbitofrontal cortex promotes habitual alcohol seeking.
  eLife 2019 Morisot N, Phamluong K, Ehinger Y, Berger AL, Moffat JJ, Ron D
• Rett syndrome from bench to bedside: recent advances.
  F1000Research 2018 Ehinger Y, Matagne V, Villard L, Roux JC
• A codon-optimized Mecp2 transgene corrects breathing deficits and improves survival in a mouse model of Rett syndrome.
  Neurobiology of disease 2016 Matagne V, Ehinger Y, Saidi L, Borges-Correia A, Barkats M, Bartoli M, Villard L, Roux JC