Yang Li, PhD
Associate Specialist
Biochemistry and Biophysics
School of Medicine

Publications (5)

Top publication keywords:
tat Gene Products, Human Immunodeficiency VirusHistonesHistone AcetyltransferasesUbiquitin-Protein LigasesAcetylationModels, MolecularUbiquitin-Conjugating EnzymesAcetyl Coenzyme ADimerizationRibonucleoproteins, Small NuclearProtein Structure, QuaternaryTranscriptional ActivationSex Determination ProcessesUbiquitinationMethylation

• The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.
  eLife 2018 Faust TB, Li Y, Bacon CW, Jang GM, Weiss A, Jayaraman B, Newton BW, Krogan NJ, D'Orso I, Frankel AD
• PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription.
  Scientific reports 2017 Faust TB, Li Y, Jang GM, Johnson JR, Yang S, Weiss A, Krogan NJ, Frankel AD
• Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex.
  Genes & development 2014 Li Y, Zhang L, Liu T, Chai C, Fang Q, Wu H, Agudelo Garcia PA, Han Z, Zong S, Yu Y, Zhang X, Parthun MR, Chai J, Xu RM, Yang M
• Structural insights into the TRIM family of ubiquitin E3 ligases.
  Cell research 2014 Li Y, Wu H, Wu W, Zhuo W, Liu W, Zhang Y, Cheng M, Chen YG, Gao N, Yu H, Wang L, Li W, Yang M
• Structural insight into Caenorhabditis elegans sex-determining protein FEM-2.
  The Journal of biological chemistry 2013 Zhang Y, Zhao H, Wang J, Ge J, Li Y, Gu J, Li P, Feng Y, Yang M