Xiaolin Zhu, MD, PhD
Clinical Fellow
Medicine
School of Medicine
Education & Training
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- Residency Internal Medicine UT Southwestern Medical Center 06/2020
- PhD Genetics and Genomics Duke University 06/2017
- Bachelor of Medicine (MD equivalent) Clinical Medicine Shanghai Jiao Tong University School of Medicine 06/2011
- Fellowship Hematology/Oncology UCSF
Interests
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- medical genetics
- cancer genetics
- precision oncology
- genomics
- precision medicine
- human genetics
Websites
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- @@xiaolin_zhu on Twitter (twitter.com)
Publications (17)
Top publication keywords:
Urologic NeoplasmsAntibodies, Monoclonal, HumanizedAntibodies, MonoclonalTransplantation ConditioningMutationHigh-Throughput Nucleotide SequencingMendelian Randomization AnalysisCarcinoma, Transitional CellEpilepsyMyelodysplastic SyndromesUrinary Bladder NeoplasmsGenetic Diseases, InbornDNA Copy Number VariationsGenetic Predisposition to DiseaseExome
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Enfortumab vedotin and pembrolizumab as new first-line standard for metastatic urothelial cancer.
Med (New York, N.Y.) 2023 Zhu X, Koshkin VS -
The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer.
Cancer research 2023 Lundberg A, Zhang M, Aggarwal R, Li H, Zhang L, Foye A, Sjöström M, Chou J, Chang K, Moreno-Rodriguez T, Shrestha R, Baskin A, Zhu X, Weinstein AS, Younger N, Alumkal JJ, Beer TM, Chi KN, Evans CP, … -
Impact of Squamous Histology on Clinical Outcomes and Molecular Profiling in Metastatic Urothelial Carcinoma Patients Treated With Immune Checkpoint Inhibitors or Enfortumab Vedotin.
Clinical genitourinary cancer 2023 Jindal T, Zhang L, Deshmukh P, Reyes K, Chan E, Kumar V, Zhu X, Maldonado E, Feng S, Johnson M, Angelidakis A, Kwon D, Desai A, Borno HT, Bose R, Wong A, Hong J, Carroll P, Meng M, Porten S, Aggarwal … -
Somatic alterations of TP53 and MDM2 associated with response to enfortumab vedotin in patients with advanced urothelial cancer.
Frontiers in oncology 2023 Jindal T, Zhu X, Bose R, Kumar V, Maldonado E, Deshmukh P, Shipp C, Feng S, Johnson MS, Angelidakis A, Kwon D, Borno HT, de Kouchkovsky I, Desai A, Aggarwal R, Fong L, Small EJ, Wong A, Porten S, Chou… -
New insights into tardive dyskinesia genetics: Implementation of whole-exome sequencing approach.
Progress in neuro-psychopharmacology & biological psychiatry 2019 Alkelai A, Greenbaum L, Heinzen EL, Baugh EH, Teitelbaum A, Zhu X, Strous RD, Tatarskyy P, Zai CC, Tiwari AK, Tampakeras M, Freeman N, Müller DJ, Voineskos AN, Lieberman JA, Delaney SL, Meltzer HY, …
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De-novo mutations in patients with chronic ultra-refractory epilepsy with onset after age five years.
European journal of medical genetics 2019 McCormack M, McGinty RN, Zhu X, Slattery L, Heinzen EL, EPIGEN Consortium, Costello DJ, Delanty N, Cavalleri GL -
Whole-exome sequencing in the evaluation of fetal structural anomalies: a prospective cohort study.
Lancet (London, England) 2019 Petrovski S, Aggarwal V, Giordano JL, Stosic M, Wou K, Bier L, Spiegel E, Brennan K, Stong N, Jobanputra V, Ren Z, Zhu X, Mebane C, Nahum O, Wang Q, Kamalakaran S, Malone C, Anyane-Yeboa K, Miller R, … -
Mutation Clearance after Transplantation for Myelodysplastic Syndrome.
The New England journal of medicine 2018 Zhu X -
De novo and inherited private variants in MAP1B in periventricular nodular heterotopia.
PLoS genetics 2018 Heinzen EL, O'Neill AC, Zhu X, Allen AS, Bahlo M, Chelly J, Chen MH, Dobyns WB, Freytag S, Guerrini R, Leventer RJ, Poduri A, Robertson SP, Walsh CA, Zhang M, Epi4K Consortium, Epilepsy Phenome/Genome… -
A case-control collapsing analysis identifies epilepsy genes implicated in trio sequencing studies focused on de novo mutations.
PLoS genetics 2017 Zhu X, Padmanabhan R, Copeland B, Bridgers J, Ren Z, Kamalakaran S, O'Driscoll-Collins A, Berkovic SF, Scheffer IE, Poduri A, Mei D, Guerrini R, Lowenstein DH, Allen AS, Heinzen EL, Goldstein DB -
Sensitivity of whole exome sequencing in detecting infantile- and late-onset Pompe disease.
Molecular genetics and metabolism 2017 Mori M, Haskell G, Kazi Z, Zhu X, DeArmey SM, Goldstein JL, Bali D, Rehder C, Cirulli ET, Kishnani PS -
Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures.
American journal of human genetics 2016 Petrovski S, Küry S, Myers CT, Anyane-Yeboa K, Cogné B, Bialer M, Xia F, Hemati P, Riviello J, Mehaffey M, Besnard T, Becraft E, Wadley A, Politi AR, Colombo S, Zhu X, Ren Z, Andrews I, Dudding-Byth T… -
Joint detection of copy number variations in parent-offspring trios.
Bioinformatics (Oxford, England) 2015 Liu Y, Liu J, Lu J, Peng J, Juan L, Zhu X, Li B, Wang Y -
Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios.
Genetics in medicine : official journal of the American College of Medical Genetics 2015 Zhu X, Petrovski S, Xie P, Ruzzo EK, Lu YF, McSweeney KM, Ben-Zeev B, Nissenkorn A, Anikster Y, Oz-Levi D, Dhindsa RS, Hitomi Y, Schoch K, Spillmann RC, Heimer G, Marek-Yagel D, Tzadok M, Han Y, … -
One gene, many neuropsychiatric disorders: lessons from Mendelian diseases.
Nature neuroscience 2014 Zhu X, Need AC, Petrovski S, Goldstein DB -
An evaluation of copy number variation detection tools from whole-exome sequencing data.
Human mutation 2014 Tan R, Wang Y, Kleinstein SE, Liu Y, Zhu X, Guo H, Jiang Q, Allen AS, Zhu M -
A gradient-boosting approach for filtering de novo mutations in parent-offspring trios.
Bioinformatics (Oxford, England) 2014 Liu Y, Li B, Tan R, Zhu X, Wang Y