Xavier Orain
Clinical Research Supervisor 1
Cardiovascular Research Inst
School of Medicine

Publications (3)

Top publication keywords:
Hereditary Sensory and Autonomic NeuropathiesCarbohydratesSulfhydryl CompoundsCystic FibrosisParkinson DiseaseHomozygoteSynucleinsNerve Growth FactorAcetylcysteinerab5 GTP-Binding ProteinsLung Diseases, ObstructiveExpectorantsSputumBrain-Derived Neurotrophic FactorPain Perception

• A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases.
  The European respiratory journal 2023 Addante A, Raymond W, Gitlin I, Charbit A, Orain X, Scheffler AW, Kuppe A, Duerr J, Daniltchenko M, Drescher M, Graeber SY, Healy AM, Oscarson S, Fahy JV, Mall MA
• A missense point mutation in nerve growth factor (NGFR100W) results in selective peripheral sensory neuropathy.
  Progress in neurobiology 2020 Yang W, Sung K, Xu W, Rodriguez MJ, Wu AC, Santos SA, Fang S, Uber RK, Dong SX, Guillory BC, Orain X, Raus J, Jolivalt C, Calcutt N, Rissman RA, Ding J, Wu C
• Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease.
  Scientific reports 2017 Fang F, Yang W, Florio JB, Rockenstein E, Spencer B, Orain XM, Dong SX, Li H, Chen X, Sung K, Rissman RA, Masliah E, Ding J, Wu C