William Ryan, MD
Professor
Otolaryngology
School of Medicine
Dr. William R. Ryan is a board-certified, fellowship-trained, head and neck oncologic surgeon and associate professor at the University of California-San Francisco (UCSF), Bakar Cancer Hospital / Helen Diller Comprehensive Cancer Center at Mission Bay in the Division of Head and Neck Oncologic and Endocrine Surgery in the Department of Otolaryngology-Head and Neck Surgery.
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Clinically, Dr. Ryan is skilled in caring for patients with benign and malignant tumors of the head and neck and salivary gland inflammatory disorders with the appropriate application of robotic, endoscopic, minimally invasive, and traditional surgical techniques. He regularly performs ultrasonography in clinic and in the operating room for his patients. He also has special expertise in transoral robotic surgery (TORS), sialendoscopy, sentinel lymph node biopsy, and regional reconstruction of the face, mouth, and neck. Dr. Ryan helps direct the Robotic Head and Neck Surgery Center, Thyroid Surgery Center, and Salivary Gland Surgery Center at UCSF.
Dr. Ryan is committed to providing adequate information and being as accessible as possible to his patients.
Dr. Ryan was a finalist for the university-wide Henry J. Kaiser teaching award for 2022. Dr. Ryan is actively involved in teaching and mentorship in the UCSF residency and fellowship training programs and the School of Medicine. He serves as the head and neck surgical oncology fellowship co-director. He also directs the year-long Prendergast clinical research fellowship for medical students.
He is a regular invited lecturer and panelist nationally and at UCSF on various aspects of head and neck surgery, salivary duct surgery, and head and neck ultrasound having conducted over 100 national lectures over his career. His research and education interests include functional quality of life outcomes after treatment of human papilloma virus associated (HPV+) oropharynx carcinoma, oral cavity cancer, and salivary tumors, the quality of life impact of sialendoscopic-assisted salivary duct surgery for chronic sialadenitis, surgeon-performed ultrasound applications for the management of salivary disease, the utility of imaging surveillance for various head and neck cancers, and the role of surgery alone for the treatment of HPV+ oropharynx carcinoma. He is the principal investigator in a clinical trial testing the drug ruxolitinib on upper aerodigestive tract squamous cell carcinoma. He has authored over 95 published peer-reviewed journal articles and 4 book chapters and edited a full book on salivary diseases. He serves on multiple committees within the American Head and Neck Society. He is a fellow of the Triological Society. He is a regular reviewer for the journals: Laryngoscope, Head and Neck, Otolaryngology-Head and Neck Surgery, JAMA-Otolaryngology-Head and Neck Surgery, and several others. He is a co-director for the following 2 annual courses: UCSF/Tripler Pacific Rim Otolaryngology-Head and Neck Surgery Update and the UCSF Sialendoscopy/Salivary Duct Surgery Update.
Dr. Ryan earned his medical degree from Stanford University School of Medicine in 2005, where he also completed his residency in otolaryngology-head and neck surgery in 2010. Following his residency, he completed a fellowship in advanced head and neck oncologic and endocrine surgery at UCSF in 2011. He joined the UCSF faculty in 2011.
Away from his career, he enjoys surfing, skiing, playing guitar, seeing music, hiking, and time with his friends and family, especially his wife, daughter, and son.
Specialty: Head and Neck Surgical Oncology, Salivary Gland and Duct Surgery and Sialendoscopy, Thyroid and Parathyroid Surgery
Expertise: Head and Neck Surgical Oncology, Transoral Robotic Surgery, Surgeon-Performed Ultrasound, Salivary Gland and Duct Surgery and Sialendoscopy, Thyroid and Parathyroid Surgery
Professional Interests: Head and Neck Tumors, transoral robotic surgery, surgeon-performed ultrasound, salivary surgery/sialoendoscopy, thyroid/parathyroid surgery, endoscopic sinus/skull base surgery, and facial reconstruction, outcomes research. salivary function in setting of oncologic treatments, head and neck surgery technique commonalities across the United States, the impact of sialendoscopy on patient symptoms, the benefits and drawbacks of head and neck cancer surveillance with radiology
Education and Training:
- Medical School: Stanford University, CA
- Internship: Stanford University, CA – Head and Neck Surgery
- Residency: Stanford University, CA – Otolaryngology-Head and Neck Surgery
- Fellowship: University of California, San Francisco – Head and Neck Oncologic Surgery
Awards and Honors:
- 1997 Phi Beta Kappa, Wesleyan University
- 2004, Best paper by a medical student award, 6th International Conference on Head and Neck Cancer, Washington D.C
- 2009, Honorable Mention-Scientific Content Award, Stanford Otolaryngology Resident Research Symposium
- 2011 University of California-San Francisco - Pinnacle Award- Highest Patient Satisfaction Award For A Clinical Division (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)
- 2012 University of California-San Francisco - Pinnacle Award - Highest Patient Satisfaction Award For A Clinical Division at UCSF (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery)
- 2013 University of California-San Francisco - Pinnacle Award (Honorable Mention / 3rd Place) - Highest Patient Satisfaction Award For A Clinical Division at UCSF (Granted to the Division of Head and Neck Oncologic/Endocrine Surgery) -American Head and Neck Society Chris O'Brien Traveling Fellow to Australia, 2022 -UCSF Henry Kaiser Inpatient Teaching Award Finalist, 2022
Awards
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- Phi Beta Kappa, Wesleyan University, 1997
Education & Training
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- M.D. School of Medicine Stanford University 2005
Interests
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- Salivary Cancer Surgery
- Head and Neck Surgery
- Transoral Robotic Surgery
- Thyroid/Parathyroid Surgery
- Salivary Duct Surgery
- In Office Surgeon-Performed Ultrasound
- Sialoendoscopy
- Upper Aerodigestive Tract Cancer Surgery
- Stroboscopy
- Thyroid Cancer Surgery
- Oral Cavity (Mouth)
- Goiter Surgery
- Upper Esophageal Surgery
- Hyperparathyroidism/Parathyroidectomy Surgery
- Oropharyx/Hypopharynx/Larynx (Throat) Surgery
- Nasopharyngolaryngoscopy
- Facial and Neck Regional Reconstruction
- Neck Dissection
- Lips
Publications (138)
Top publication keywords:
Mouth NeoplasmsSalivary Gland DiseasesNeck DissectionPapillomavirus InfectionsPapillomaviridaeHead and Neck NeoplasmsSalivary DuctsSalivary GlandsAlphapapillomavirusOropharyngeal NeoplasmsCarcinoma, Squamous CellRobotic Surgical ProceduresEndoscopySialadenitisOral Surgical Procedures
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Rate of occult metastasis in lip squamous cell carcinoma: A systematic review and meta-analysis.
Head & neck 2024 Kansara S, Oral E, Sarkar I, Sandulache V, Mualla R, Walvekar RR, Ryan W, Ha P -
Prognostic risk factors of buccal squamous cell carcinoma: A case-control study.
Head & neck 2024 Callander JK, Souza SS, Eltawil Y, El-Sayed IH, George JR, Ha P, Ryan WR, Xu MJ, Heaton CM -
Proposal for standardized ultrasound analysis of the salivary glands: Part 1 submandibular gland.
Laryngoscope investigative otolaryngology 2024 Hoffman HT, Koch M, Witt RL, Ryan WR, Zenk J, Katz P, Rahmati R, Rassekh C, Donato F, McCulloch TM, Joshi AS, Chang JL, Gillespie MB, Pichardo PFA, Orloff LA, Marcelino A, Wenzel P, Cohen D, … -
Oncologic Safety of Close Margins in Patients With Low- to Intermediate-Grade Major Salivary Gland Carcinoma.
JAMA otolaryngology-- head & neck surgery 2024 Sajisevi M, Nguyen K, Callas P, Holcomb AJ, Vural E, Davis KP, Thomas CM, Plonowska-Hirschfeld KA, Stein JS, Eskander A, Kakarala K, Enepekides DJ, Hier MP, Ryan WR, American Head and Neck Society … -
Circulating tumor HPV DNA assessments after surgery for human papilloma virus-associated oropharynx carcinoma.
American journal of otolaryngology 2023 Souza SS, Stephens EM, Bourdillon AT, Bhethanabotla R, Farzal Z, Plonowska-Hirschfeld K, Qualliotine JR, Heaton CM, Ha PK, Ryan WR
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The neutrophil-to-lymphocyte ratio in salivary gland cancers treated with pembrolizumab.
Head & neck 2023 Lee RH, Truong A, Wu X, Kang H, Algazi AP, El-Sayed IH, George JR, Heaton CM, Ryan WR, Ha PK, Wai KC -
Treatment Modality Impact on Patient-Reported Quality of Life in Human Papilloma Virus-Associated Oropharyngeal Carcinoma.
The Laryngoscope 2023 Plonowska-Hirschfeld KA, Gulati A, Stephens EM, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi A, Kang H, Ryan WR -
Spondylodiscitis and Spinal Epidural Abscess After Transoral Robotic Surgery Radical Tonsillectomy.
OTO open 2023 Callander JK, Clark AJ, Dillon W, Ryan WR -
A prospective evaluation of neck and shoulder function following treatments of early-stage human papillomavirus-associated oropharynx cancer.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2023 Gulati A, Plonowska-Hirschfeld K, Stephens EM, Kansara S, Zebolsky AL, Ochoa E, Xu MJ, Ha PK, Heaton CM, Yom SS, Chan JW, Algazi AP, Kang H, Ryan WR -
Effects of feeding CLOSTAT (Bacillus subtilis PB6) on the clinical health, performance, and carcass characteristics of feedlot steers1.
Translational animal science 2023 Ryan WR, DeSocio ES, Youngers ME, Lockard CG, Richards CJ, Trojan SJ, Hergenreder JE, Wilson BK -
Prospective quality of life outcomes for human papillomavirus associated oropharynx cancer patients after surgery alone.
American journal of otolaryngology 2023 Stephens EM, Plonowska-Hirschfeld K, Gulati A, Kansara S, Qualliotine J, Zelbolsky AL, van Zante A, Ha PK, Heaton CM, Ryan WR -
Patterns of Postoperative Trismus Following Mandibulectomy and Fibula Free Flap Reconstruction.
Cancers 2023 Lee RH, Evans C, Laus J, Sanchez C, Wai KC, Knott PD, Seth R, El-Sayed IH, George JR, Ryan WR, Heaton CM, Park AM, Ha PK -
STAT3 Activation as a Predictive Biomarker for Ruxolitinib Response in Head and Neck Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Qureshy Z, Li H, Zeng Y, Rivera J, Cheng N, Peterson CN, Kim MO, Ryan WR, Ha PK, Bauman JE, Wang SJ, Long SR, Johnson DE, Grandis JR -
Longitudinal Analysis of Swallowing Displacement Kinematics After Oropharyngeal Cancer Treatment.
The Laryngoscope 2022 Kidane J, Laus J, Gulati A, Gochman GE, Schneider SL, Chan JW, Yom SS, Ha P, Boscardin WJ, Ryan WR, Ma Y -
Symptom Outcomes After Sialendoscopy-Assisted Salivary Duct Surgery: A Prospective 6-Year Study.
The Laryngoscope 2022 Callander JK, Plonowska-Hirschfeld K, Gulati A, Chang JL, Ryan WR -
Feasibility of accelerated image-guided high-dose-rate interstitial brachytherapy with inverse planning simulated annealing (IPSA-HDRBT) for post-operative treatment of pathologically node-negative squamous cell carcinomas of the oral tongue.
Brachytherapy 2022 Cheung CK, Chew J, Wai K, Calkins SM, Ha PK, Ryan WR, Cunha A, Yom SS, Hsu IC, Chan JW -
An Updated Patient-Centered Sialadenitis Instrument: The Obstructive Salivary Problem Impact Test (SPIT).
The Laryngoscope 2022 Gulati A, Cognetti DM, Cohen DS, Ogden MA, Schaitkin BM, Walvekar RR, Ryan WR, Chang JL -
Prevalence of human papillomavirus in head and neck cancers at tertiary care centers in the United States over time.
Cancer 2022 Scott-Wittenborn N, D'Souza G, Tewari S, Rooper L, Troy T, Drake V, Bigelow EO, Windon MJ, Ryan WR, Ha PK, Kiess AP, Miles B, Westra WH, Mydlarz WK, Eisele DW, Fakhry C -
Adjuvant therapy improves survival in pT4aN0 oral cavity squamous cell carcinoma with bone invasion.
American journal of otolaryngology 2021 Stanford-Moore GB, Sola AM, Chan J, El-Sayed I, George J, Ha P, Ryan WR, Heaton CM -
Risk of Pathologic Extranodal Extension and Other Adverse Features After Transoral Robotic Surgery in Patients With HPV-Positive Oropharynx Cancer.
JAMA otolaryngology-- head & neck surgery 2021 Zebolsky AL, George E, Gulati A, Wai KC, Carpenter P, Van Zante A, Ha PK, Heaton CM, Ryan WR -
Impact of Smoking and Primary Tumor Subsite on Recurrence in HPV-Associated Oropharyngeal Squamous Cell Carcinoma.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2021 Lee RH, Salesky M, Benjamin T, El-Sayed IH, George JR, Ha PK, Ryan WR, Heaton CM -
The Science and Art of Salivary Care.
Otolaryngologic clinics of North America 2021 Gillespie MB, Ryan WR -
Transoral Excision of Parapharyngeal Space Tumors.
Otolaryngologic clinics of North America 2021 Larson AR, Ryan WR -
A prospective study of patient-reported xerostomia-related outcomes after parotidectomy.
Laryngoscope investigative otolaryngology 2021 Brodie KD, Zebolsky AL, Ochoa E, Ha PK, Heaton CM, El-Sayed IH, Ryan WR -
Oncologic outcomes of human papillomavirus-associated oropharynx carcinoma treated with surgery alone: A 12-institution study of 344 patients.
Cancer 2021 Ryan WR, Xu MJ, Ochoa E, Plonowska-Hirschfeld KA, Zebolsky AL, Ha PK, Bewley AF, Mallen-St Clair J, Joshi AS, Coffey CS, Faraji F, MacDonald BV, Houlton JJ, Gobillot TA, Curry JM, Philips R, Hackman … -
Botulinum toxin for chronic parotid sialadenitis: A case series and systematic review.
Laryngoscope investigative otolaryngology 2021 Strohl MP, Chang CF, Ryan WR, Chang JL -
Impact of surgical margins on local control in patients undergoing single-modality transoral robotic surgery for HPV-related oropharyngeal squamous cell carcinoma.
Head & neck 2021 Holcomb AJ, Herberg M, Strohl M, Ochoa E, Feng AL, Abt NB, Mokhtari TE, Suresh K, McHugh CI, Parikh AS, Sadow P, Faquin W, Faden D, Deschler DG, Varvares MA, Lin DT, Fakhry C, Ryan WR, Richmon JD -
Obstructive Sialadenitis: Stones and Stenoses.
Current Otorhinolaryngology Reports 2021 Andrew R. Larson, Keonho Albert Kong, William R. Ryan, Rohan R. Walvekar -
Patient-Reported Outcomes of Split-Thickness Skin Grafts for Floor of Mouth Cancer Reconstruction.
ORL; journal for oto-rhino-laryngology and its related specialties 2021 Larson AR, Han M, Webb KL, Ochoa E, Stanford-Moore G, El-Sayed IH, George JR, Ha PK, Heaton CM, Ryan WR -
Nasogastric tube feeding after transoral robotic surgery for oropharynx carcinoma.
American journal of otolaryngology 2021 Plonowska KA, Ochoa E, Zebolsky AL, Patel N, Hoppe KR, Ha PK, Heaton CM, Ryan WR -
Predicting Adverse Histopathology and Need for Postsurgical Adjuvant Therapy for Human Papilloma Virus-Associated Oropharynx Carcinoma.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2021 Ochoa E, Stanford-Moore G, Fakhry C, Ryan WR -
Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva.
Cell reports 2020 Saitou M, Gaylord EA, Xu E, May AJ, Neznanova L, Nathan S, Grawe A, Chang J, Ryan W, Ruhl S, Knox SM, Gokcumen O -
Head and neck surgery during the coronavirus-19 pandemic: The University of California San Francisco experience.
Head & neck 2020 Wai KC, Xu MJ, Lee RH, El-Sayed IH, George JR, Heaton CM, Knott PD, Park AM, Ryan WR, Seth R, Ha PK -
Sialendoscopy in Chronic Obstructive Sialadenitis Without Sialolithiasis: A Prospective Cohort Study.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2020 Plonowska KA, Ochoa E, Ryan WR, Chang JL -
Patterns of Nodal Metastases and Predictors of Occult Disease in HPV-Associated Oropharynx Cancer.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2020 Stanford-Moore GB, Ochoa E, Larson A, Han M, Hoppe K, Ryan WR -
Salivary Gland Neoplasms.
Current Otorhinolaryngology Reports 2020 Anne C. Kane, William R. Ryan, David Cognetti -
Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology.
Head & neck 2020 Singer MC, Marchal F, Angelos P, Bernet V, Boucai L, Buchholzer S, Burkey B, Eisele D, Erkul E, Faure F, Freitag SK, Gillespie MB, Harrell RM, Hartl D, Haymart M, Leffert J, Mandel S, Miller BS, … -
Abstract A28: Predictive factors for mortality after surgery alone for human papilloma virus-associated oropharynx squamous cell carcinoma: Analysis of the National Cancer Database.
Clinical Cancer Research 2020 Mary Han, Gaelen B. Stanford-Moore, David W. Schoppy, William R. Ryan -
Modified technique of submandibular gland transfer followed by intensity modulated radiotherapy to reduce xerostomia in head and neck cancer patients.
Head & neck 2020 Chang CF, Ei-Sayed IH, George JR, Heaton CM, Ryan WR, Susko MS, Yom SS, Ha PK -
Improved Tumor Control Related to Radiotherapy Technological Development for Hypopharyngeal Cancer.
The Laryngoscope 2020 Susko MS, Lazar AA, Dhar S, Chan JW, Shiao SL, Chapman CH, Johnson J, Quivey JM, Ryan WR, Heaton CM, Ha PK, Yom SS -
Patient-Reported Quality of Life After Resection With Primary Closure for Oral Tongue Carcinoma.
The Laryngoscope 2020 Ochoa E, Larson AR, Han M, Webb KL, Stanford-Moore GB, El-Sayed IH, George JR, Ha PK, Heaton CM, Ryan WR -
HPV-positive Squamous Cell Carcinoma of the Larynx, Oral Cavity, and Hypopharynx: Clinicopathologic Characterization With Recognition of a Novel Warty Variant.
The American journal of surgical pathology 2020 Rooper LM, Windon MJ, Hernandez T, Miles B, Ha PK, Ryan WR, Van Zante A, Eisele DW, D'Souza G, Fakhry C, Westra WH -
Machine Learning for Predicting Complications in Head and Neck Microvascular Free Tissue Transfer.
The Laryngoscope 2020 Formeister EJ, Baum R, Knott PD, Seth R, Ha P, Ryan W, El-Sayed I, George J, Larson A, Plonowska K, Heaton C -
Distinct biomarker and behavioral profiles of human papillomavirus-related oropharynx cancer patients by age.
Oral oncology 2019 Fakhry C, Waterboer T, Westra WH, Rooper LM, Windon M, Troy T, Koch W, Gourin CG, Bender N, Yavvari S, Kiess AP, Miles BA, Ryan WR, Ha PK, Eisele DW, D'Souza G -
Predictors of Mortality in HPV-Associated Oropharynx Carcinoma Treated With Surgery Alone.
The Laryngoscope 2019 Han M, Stanford-Moore GB, Larson AR, Schoppy DW, Cognetti DM, Joshi AS, Houlton JJ, Ryan WR -
Beyond Depth of Invasion: Adverse Pathologic Tumor Features in Early Oral Tongue Squamous Cell Carcinoma.
The Laryngoscope 2019 Larson AR, Kemmer J, Formeister E, El-Sayed I, Ha P, George J, Ryan W, Chan E, Heaton C -
Patterns of care and survival impact of adjuvant chemoradiotherapy for oropharyngeal cancer with intermediate-risk features.
Head & neck 2019 Goel AN, Sangar S, Mukdad L, Heaton CM, Ryan WR, Wang MB, Long JL, St John MA -
Treatment modality impact on quality of life for human papillomavirus-associated oropharynx cancer.
The Laryngoscope 2019 Xu MJ, Plonowska KA, Gurman ZR, Humphrey AK, Ha PK, Wang SJ, El-Sayed IH, Heaton CM, George JR, Yom SS, Algazi AP, Ryan WR -
Sex differences in HPV immunity among adults without cancer.
Human vaccines & immunotherapeutics 2019 Windon MJ, Waterboer T, Hillel AT, Chien W, Best S, Stewart C, Akst L, Troy T, Bender N, Miles B, Ryan WR, Mandal R, Pitman K, Eisele DW, Fakhry C, D'Souza G -
Socioeconomic disparities in a population of patients undergoing total thyroidectomy for benign disease.
Head & neck 2018 Wu TJ, Ha PK, El-Sayed IH, George JR, Heaton CM, Ryan WR, Russell MD -
Human Papillomavirus-Associated Oropharyngeal Cancer: Patterns of Nodal Disease.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2018 Plonowska KA, Strohl MP, Wang SJ, Ha PK, George JR, Heaton CM, El-Sayed IH, Mallen-St Clair J, Ryan WR -
Advanced head and neck surgical techniques: A survey of US otolaryngology resident perspectives.
Auris, nasus, larynx 2018 Plonowska KA, Ha PK, Ryan WR -
One-Year symptom outcomes after sialolithiasis treatment with sialendoscopy-assisted salivary duct surgery.
The Laryngoscope 2018 Ryan WR, Plonowska KA, Gurman ZR, Aubin-Pouliot A, Chang JL -
One-year outcomes of sialendoscopic-assisted salivary duct surgery for sialadenitis without sialolithiasis.
The Laryngoscope 2018 Plonowska KA, Gurman ZR, Humphrey A, Chang JL, Ryan WR -
A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.
Nature medicine 2018 Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, … -
Shorter interval between radiation therapy and salvage laryngopharyngeal surgery increases complication rates following microvascular free tissue transfer.
American journal of otolaryngology 2018 Formeister EJ, Sean Alemi A, El-Sayed I, George JR, Ha P, Daniel Knott P, Ryan WR, Seth R, Tamplen ML, Heaton CM -
Human Papillomavirus in the Mouth and Throat: More Widespread Than Expected?
JAMA otolaryngology-- head & neck surgery 2018 Ryan WR, Plonowska K -
Undifferentiated pleomorphic sarcoma: Factors predictive of adverse outcomes.
Journal of the American Academy of Dermatology 2018 Winchester D, Lehman J, Tello T, Chimato N, Hocker T, Kim S, Chang J, Markey J, Yom SS, Ryan W, Mully T, Hodge D, Otley C, Arron ST -
Squamous Cell Carcinoma of the Soft Palate in the United States: A Population-Based Study.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2018 Chan CK, Han AY, Alonso JE, Xu MJ, Mallen-St Clair J, Heaton CM, Ryan WR, Kuan EC, St John MA -
Increasing prevalence of human papillomavirus-positive oropharyngeal cancers among older adults.
Cancer 2018 Windon MJ, D'Souza G, Rettig EM, Westra WH, van Zante A, Wang SJ, Ryan WR, Mydlarz WK, Ha PK, Miles BA, Koch W, Gourin C, Eisele DW, Fakhry C -
Mortality risk after clinical management of recurrent and metastatic adenoid cystic carcinoma.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 2018 Xu MJ, Wu TJ, van Zante A, El-Sayed IH, Algazi AP, Ryan WR, Ha PK, Yom SS -
Surgeon-performed ultrasound for the assessment of parotid masses.
American journal of otolaryngology 2018 Zheng M, Plonowska KA, Strohl MP, Ryan WR -
Prognostic factors for human papillomavirus-positive and negative oropharyngeal carcinomas.
The Laryngoscope 2018 Yin LX, D'Souza G, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig EM, Ryan WR, Ha PK, Wentz A, Koch W, Eisele DW, Fakhry C -
CD29 is highly expressed on epithelial, myoepithelial, and mesenchymal stromal cells of human salivary glands.
Oral diseases 2018 Togarrati PP, Dinglasan N, Desai S, Ryan WR, Muench MO -
Major prognostic factors for recurrence and survival independent of the American Joint Committee on Cancer eighth edition staging system in patients with cutaneous squamous cell carcinoma treated with multimodality therapy.
Head & neck 2018 Xu MJ, Lazar AA, Garsa AA, Arron ST, Ryan WR, El-Sayed IH, George JR, Algazi AP, Heaton CM, Ha PK, Yom SS -
High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells.
Stem cell reports 2018 Garcia SM, Tamaki S, Lee S, Wong A, Jose A, Dreux J, Kouklis G, Sbitany H, Seth R, Knott PD, Heaton C, Ryan WR, Kim EA, Hansen SL, Hoffman WY, Pomerantz JH -
Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.
EMBO molecular medicine 2018 Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, Chang JL, Ryan WR, Tward AD, Knox SM -
The survival impact of surgical therapy in squamous cell carcinoma of the hard palate.
The Laryngoscope 2018 Alonso JE, Han AY, Kuan EC, Strohl M, Clair JM, St John MA, Ryan WR, Heaton CM -
Salivary Fine Needle Aspiration Biopsy.
Gland-Preserving Salivary Surgery 2018 William R. Ryan, A. Sean Alemi, Annemieke van Zante -
Squamous cell carcinoma of unknown primary of the head and neck: Favorable prognostic factors comparable to those in oropharyngeal cancer.
Head & neck 2017 Zhou MJ, van Zante A, Lazar AA, Groppo ER, Garsa AA, Ryan WR, El-Sayed IH, Eisele DW, Yom SS -
Abstract 17: Patterns of neck nodal metastases and recurrence in human papilloma virus-associated oropharyngeal squamous cell carcinoma after neck dissection.
Cancer Genomics and Signatures of Mutational Processes in Human Cancer 2017 Madeleine P. Strohl, Steven J. Wang, Patrick K. Ha, Jonathan R. George, Chase M. Heaton, Ivan H. El-Sayed, Jon Mallen St Clair, William R. Ryan -
Comparison of Output Volume Thresholds for Drain Removal After Selective Lateral Neck Dissection: A Randomized Clinical Trial.
JAMA otolaryngology-- head & neck surgery 2017 Tamplen ML, Tamplen J, Shuman E, Heaton CM, George JR, Wang SJ, Ryan WR -
A Novel Approach to Oropharyngeal Foreign Body Removal.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2017 Strohl MP, Dewyer NA, Sckolnick J, Ryan WR -
Prevalence of Highly Self-Directed Care Among Patients with HPV-Associated Oropharyngeal Cancer.
International Journal of Radiation Oncology • Biology • Physics 2017 C.H. Chapman, W.R. Ryan, S.S. Yom -
Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients with Cutaneous Squamous Cell Carcinoma Treated with Multimodality Therapy.
International Journal of Radiation Oncology • Biology • Physics 2017 M. Xu, A.A. Garsa, A. Lazar, S. Arron, W.R. Ryan, I. El-Sayed, J. George, A. Algazi, C. Heaton, P. Ha, S.S. Yom -
Surgeon-Performed Ultrasound for Chronic Obstructive Sialadenitis Helps Predict Sialendoscopic Findings and Outcomes.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2017 Larson AR, Aubin-Pouliot A, Delagnes E, Zheng M, Chang JL, Ryan WR -
The COMMENCE trial: 2-year outcomes with an aortic bioprosthesis with RESILIA tissue.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2017 Puskas JD, Bavaria JE, Svensson LG, Blackstone EH, Griffith B, Gammie JS, Heimansohn DA, Sadowski J, Bartus K, Johnston DR, Rozanski J, Rosengart T, Girardi LN, Klodell CT, Mumtaz MA, Takayama H, … -
Salivary duct stenosis: Short-term symptom outcomes after sialendoscopy-assisted salivary duct surgery.
The Laryngoscope 2017 Delagnes EA, Zheng M, Aubin-Pouliot A, Chang JL, Ryan WR -
Volumetric Growth Rate of Recurrent Pleomorphic Adenoma.
The Annals of otology, rhinology, and laryngology 2017 Naunheim M, Wu X, Ryan WR, Wang SJ, Heaton CM -
Identification and characterization of a rich population of CD34+ mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands.
Scientific reports 2017 Togarrati PP, Sasaki RT, Abdel-Mohsen M, Dinglasan N, Deng X, Desai S, Emmerson E, Yee E, Ryan WR, da Silva MCP, Knox SM, Pillai SK, Muench MO -
(P060) Squamous Cell Carcinoma of Unknown Primary of the Head and Neck: “Low-Risk” Prognostic Factors for Disease Control and Survival Reminiscent of Oropharyngeal Cancers.
International Journal of Radiation Oncology • Biology • Physics 2017 Margaret J. Zhou, Annemieke Van Zante, Ann A. Lazar, Eli R. Groppo, Adam A. Garsa, William R. Ryan, Ivan H. El-Sayed, David W. Eisele, Sue S. Yom -
(P069) Prognostic Factors for Recurrence and Survival Independent of the Revised AJCC 8th Edition Staging System in Patients With Cutaneous Squamous Cell Carcinoma.
International Journal of Radiation Oncology • Biology • Physics 2017 Melody J. Xu, Adam A. Garsa, Ann Lazar, Sarah T. Arron, William R. Ryan, Ivan El-Sayed, Alain A. Algazi, Jonathan George, Patrick Ha, Sue S. Yom -
The effect of submandibular gland preservation during level 1B neck dissection on postoperative xerostomia.
Auris, nasus, larynx 2017 Markey JD, Morrel WG, Wang SJ, Ryan WR -
A feasibility and efficacy trial of a hand-held humidification device in patients undergoing radiotherapy for head and neck cancer.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2017 Ghosh P, Lazar AA, Ryan WR, Yom SS -
The prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer.
Cancer 2017 Fakhry C, Westra WH, Wang SJ, van Zante A, Zhang Y, Rettig E, Yin LX, Ryan WR, Ha PK, Wentz A, Koch W, Richmon JD, Eisele DW, D'Souza G -
Differences in the Prevalence of Human Papillomavirus (HPV) in Head and Neck Squamous Cell Cancers by Sex, Race, Anatomic Tumor Site, and HPV Detection Method.
JAMA oncology 2017 D'Souza G, Westra WH, Wang SJ, van Zante A, Wentz A, Kluz N, Rettig E, Ryan WR, Ha PK, Kang H, Bishop J, Quon H, Kiess AP, Richmon JD, Eisele DW, Fakhry C -
Does a Standalone Cancer Center Improve Head and Neck Microsurgical Outcomes?
Journal of reconstructive microsurgery 2017 Tamplen ML, Tamplen J, Torrecillas V, Seth R, Ricceri S, Hemmat S, Heaton C, Ryan WR, Knott PD -
Transoral robotic surgery (TORS) for excision of a retropharyngeal intramuscular lipoma.
Auris, nasus, larynx 2016 Heaton CM, Ahmed SR, Ryan WR -
Chronic parotitis with multiple calcifications: Clinical and sialendoscopic findings.
The Laryngoscope 2016 Jáuregui E, Kiringoda R, Ryan WR, Eisele DW, Chang JL -
Earlier and more specific detection of persistent neck disease with diffusion-weighted MRI versus subsequent PET/CT after definitive chemoradiation for oropharyngeal squamous cell carcinoma.
Head & neck 2016 Yu Y, Mabray M, Silveira W, Shen PY, Ryan WR, Uzelac A, Yom SS -
Sialadenitis without sialolithiasis: Prospective outcomes after sialendoscopy-assisted salivary duct surgery.
The Laryngoscope 2016 Delagnes EA, Aubin-Pouliot A, Zheng M, Chang JL, Ryan WR -
Volumetric Growth of Cervical Schwannoma as a Predictor of Surgical Intervention.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2016 Alemi AS, Heaton CM, Ryan WR, El-Sayed I, Wang SJ -
Neck Dissection Technique Commonality and Variance: A Survey on Neck Dissection Technique Preferences among Head and Neck Oncologic Surgeons in the American Head and Neck Society.
International archives of otorhinolaryngology 2016 Hemmat SM, Wang SJ, Ryan WR -
Clinicopathologic characteristics and outcomes of recurrent oropharyngeal squamous cell carcinoma.
American journal of otolaryngology 2016 Heaton CM, Yu K, Calkins S, George JR, Ryan WR, Wang SJ -
How, when, and from whom neck dissection operative technique is learned: An international survey on neck dissection education among head and neck oncologic surgeons.
American journal of otolaryngology 2016 Hemmat S, Wang SJ, Ryan WR -
Benefits of Immediate Extubation Following Free Tissue Transfer for Head and Neck Reconstruction.
Journal of reconstructive microsurgery 2016 Tamplen ML, Ricceri S, Hemmat S, Seth R, Ryan WR, Knott PD -
Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 2016 Singer L, Calkins SM, Horvai AE, Ryan WR, Yom SS -
Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study.
The Laryngoscope 2016 Aubin-Pouliot A, Delagnes EA, Chang JL, Ryan WR -
Early Detection of Persistent Neck Disease With Diffusion-Weighted MRI Following Chemoradiation for Squamous Cell Carcinomas of the Oropharynx.
International Journal of Radiation Oncology • Biology • Physics 2015 Y. Yu, M. Mabray, W.R. Silveira, P.Y. Shen, W.R. Ryan, A. Uzelac, S.S. Yom -
Anterolateral Thigh Adipofascial Flap: A New Option for Scalp Reconstruction.
Journal of reconstructive microsurgery 2015 Markey JD, Seth R, Wang SJ, Ryan WR, El-Sayed IH, Knott PD -
Growth rate characteristics of Warthin's tumours of the parotid gland.
International journal of oral and maxillofacial surgery 2015 Schwalje AT, Uzelac A, Ryan WR -
The Chronic Obstructive Sialadenitis Symptoms Questionnaire to assess sialendoscopy-assisted surgery.
The Laryngoscope 2015 Aubin-Pouliot A, Delagnes EA, Eisele DW, Chang JL, Ryan WR -
Prognostic significance of hyoid bone invasion in advanced base of tongue carcinoma treated by chemoradiation.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2015 Heaton CM, Al-Shwaiheen F, Liu CS, Yom SS, Ryan WR -
The Limitations of Routine Magnetic Resonance Imaging for Long-Term Post-Treatment Locoregional Surveillance of Salivary Carcinoma.
ORL; journal for oto-rhino-laryngology and its related specialties 2015 Hemmat SM, Wang SJ, Uzelac A, Yom SS, Ryan WR -
Trans-oral robotic surgery and surgeon-performed trans-oral ultrasound for intraoperative location and excision of an isolated retropharyngeal lymph node metastasis of papillary thyroid carcinoma.
American journal of otolaryngology 2015 Goepfert RP, Liu C, Ryan WR -
The advantages and drawbacks of routine magnetic resonance imaging for long-term post-treatment locoregional surveillance of oral cavity squamous cell carcinoma.
American journal of otolaryngology 2015 Al-Shwaiheen FA, Wang SJ, Uzelac A, Yom SS, Ryan WR -
Development of a chemoradiation therapy toxicity staging system for oropharyngeal carcinoma.
The Laryngoscope 2014 Goepfert RP, Yom SS, Ryan WR, Cheung SW -
Preoperative β-blocker use in coronary artery bypass grafting surgery: national database analysis.
JAMA internal medicine 2014 Brinkman W, Herbert MA, O'Brien S, Filardo G, Prince S, Dewey T, Magee M, Ryan W, Mack M -
Elective lymphadenectomy during salvage for locally recurrent head and neck squamous cell carcinoma after radiation.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2014 Prendes BL, Aubin-Pouliot A, Egbert N, Ryan WR -
Surgeon-performed ultrasound and transfacial sialoendoscopy for complete parotid duct stenosis.
The Laryngoscope 2013 Ryan WR, Chang JL, Eisele DW -
Prognostic Significance of Hyoid Bone Invasion in Advanced Base of Tongue Carcinoma Treated by Chemoradiation.
Otolaryngology 2013 Chase Heaton, Chia-Shang Liu, Fatemah Al-Shwaiheen, William R. Ryan -
Diffusion-Weighted Imaging Compared to 3-month PET/CT to Predict Response in the Irradiated Neck.
International Journal of Radiation Oncology • Biology • Physics 2012 W.R. Silveira, P.Y. Shen, J. Tan, C.M. Glastonbury, J.M. Quivey, W.R. Ryan, S.J. Wang, S.S. Yom -
Intraoperative tumor localization with surgeon-performed ultrasound-guided needle dye injection.
The Laryngoscope 2011 Ryan WR, Orloff LA -
Correlations between symptoms, nasal endoscopy, and in-office computed tomography in post-surgical chronic rhinosinusitis patients.
The Laryngoscope 2011 Ryan WR, Ramachandra T, Hwang PH -
Safety of a preservative-free acidified saline nasal spray: a randomized, double-blind, placebo-controlled, crossover clinical trial.
Archives of otolaryngology--head & neck surgery 2010 Ryan WR, Hwang PH -
A prospective evaluation of the efficacy of topical adhesive pads for the reduction of facial rhytids.
Archives of facial plastic surgery 2009 Ryan WR, Most SP -
Long-term great auricular nerve morbidity after sacrifice during parotidectomy.
The Laryngoscope 2009 Ryan WR, Fee WE -
Great auricular nerve morbidity after nerve sacrifice during parotidectomy.
Archives of otolaryngology--head & neck surgery 2006 Ryan WR, Fee WE -
Positron-emission tomography for surveillance of head and neck cancer.
The Laryngoscope 2005 Ryan WR, Fee WE, Le QT, Pinto HA -
Crohn's disease patients who quit smoking have a reduced risk of reoperation for recurrence.
American journal of surgery 2004 Ryan WR, Allan RN, Yamamoto T, Keighley MR -
Patients with Crohn's disease are unaware of the risks that smoking has on their disease.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003 Ryan WR, Ley C, Allan RN, Keighley MR -
Treatment outcome in individuals with chronic pain: is the Pain Stages of Change Questionnaire (PSOCQ) a useful tool?
Pain 2002 Strong J, Westbury K, Smith G, McKenzie I, Ryan W -
Patient satisfaction after carotid endarterectomy using a selective policy of local anesthesia.
American journal of surgery 2000 Quigley TM, Ryan WR, Morgan S -
Arthroscopic ankle fusion.
Connecticut medicine 1997 Fisher RL, Ryan WR, Dugdale TW, Zimmermann GA -
Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs).
Bioorganic & medicinal chemistry 1997 Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan RK -
Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs.
The Journal of pharmacology and experimental therapeutics 1995 Adams IB, Ryan W, Singer M, Thomas BF, Compton DR, Razdan RK, Martin BR -
A novel class of potent tetrahydrocannabinols (THCS): 2'-yne-delta 8- and delta 9-THCS.
Life sciences 1995 Ryan W, Singer M, Razdan RK, Compton DR, Martin BR -
Pharmacological and behavioral evaluation of alkylated anandamide analogs.
Life sciences 1995 Adams IB, Ryan W, Singer M, Razdan RK, Compton DR, Martin BR -
Characteristics of a two-site immunoradiometric assay for human skeletal alkaline phosphatase in serum.
Clinical chemistry 1994 Panigrahi K, Delmas PD, Singer F, Ryan W, Reiss O, Fisher R, Miller PD, Mizrahi I, Darte C, Kress BC -
Evaluation of factors affecting the performance of enzymatic SPan-1 immunoassays for pancreatic cancer.
Journal of immunological methods 1989 Ho JJ, Chung YS, Ryan W, Henslee JG, Kim YS -
Mucin-like antigens in a human pancreatic cancer cell line identified by murine monoclonal antibodies SPan-1 and YPan-1.
Cancer research 1988 Ho JJ, Chung YS, Fujimoto Y, Bi N, Ryan W, Yuan SZ, Byrd JC, Kim YS -
A district general hospital experience of surgical treatment of gastric and duodenal ulcer from 1970 to 1982.
Surgery, gynecology & obstetrics 1988 McEntee G, Ryan W, Peel AL, Rosenberg IL, Devlin HB -
Penetrating injuries of the Iliac vessels. Early recognition and management.
American journal of surgery 1982 Ryan W, Snyder W, Bell T, Hunt J -
Current status of laryngectomee rehabilitation: III. understanding of esophageal speech.
American journal of otolaryngology 1982 Ryan W, Gates GA, Cantu E, Hearne EM -
Current status of laryngectomee rehabilitation: IV. attitudes about laryngectomee rehabilitation should change.
American journal of otolaryngology 1982 Gates GA, Ryan W, Lauder E -
Current status of laryngectomee rehabilitation: I. Results of therapy.
American journal of otolaryngology 1982 Gates GA, Ryan W, Cooper JC, Lawlis GF, Cantu E, Hayashi T, Lauder E, Welch RW, Hearne E -
Current status of laryngectomee rehabilitation: II. Causes of failure.
American journal of otolaryngology 1982 Gates GA, Ryan W, Cantu E, Hearne E -
The post-thaw viability of red blood cells of ACD and CPD blood preserved in the frozen state with and without added adenine.
Transfusion 1972 Gibson JG, Tullis JL, Tinch RJ, Ryan WR, DiForte S