William Nyberg, PhD
Postdoctoral Scholar
Medicine
School of Medicine

Publications (5)

Top publication keywords:
Antigens, NeoplasmGene LibraryLeukemiaCRISPR-Cas SystemsImmunotherapy, AdoptiveDependovirusCell- and Tissue-Based Therapyras GTPase-Activating ProteinsGene Knockdown TechniquesExerciseNeoplasmsGene TargetingT-LymphocytesMiceGenetic Engineering

• Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection.
  bioRxiv : the preprint server for biology 2024 Chang CR, Vykunta VS, Goodman DB, Muldoon JJ, Nyberg WA, Liu C, Allain V, Rothrock A, Wang CH, Marson A, Shy BR, Eyquem J
• Light induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo.
  bioRxiv : the preprint server for biology 2023 Pulgarin DV, Pelo N, Ferrandiz L, Trselic T, Nyberg WA, Bowlin G, Espinosa A
• Modular pooled discovery of synthetic knockin sequences to program durable cell therapies.
  Cell 2023 Blaeschke F, Chen YY, Apathy R, Daniel B, Chen AY, Chen PA, Sandor K, Zhang W, Li Z, Mowery CT, Yamamoto TN, Nyberg WA, To A, Yu R, Bueno R, Kim MC, Schmidt R, Goodman DB, Feuchtinger T, Eyquem J, …
• An evolved AAV variant enables efficient genetic engineering of murine T cells.
  Cell 2023 Nyberg WA, Ark J, To A, Clouden S, Reeder G, Muldoon JJ, Chung JY, Xie WH, Allain V, Steinhart Z, Chang C, Talbot A, Kim S, Rosales A, Havlik LP, Pimentel H, Asokan A, Eyquem J
• RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
  Nature 2022 Carnevale J, Shifrut E, Kale N, Nyberg WA, Blaeschke F, Chen YY, Li Z, Bapat SP, Diolaiti ME, O'Leary P, Vedova S, Belk J, Daniel B, Roth TL, Bachl S, Anido AA, Prinzing B, Ibañez-Vega J, Lange S, …