William Krause, PhD
Specialist
Cellular Molecular Pharmacology
School of Medicine

Awards

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• Postdoctoral Fellowship, American Heart Association

Publications (15)

Top publication keywords:
Signal TransductionReceptors, AndrogenProto-Oncogene Proteins c-bcl-6Energy MetabolismPhysical ExertionEstrogensVentromedial Hypothalamic NucleusMelanocortinsLongevityHepatocyte Nuclear Factor 3-alphaAlternative SplicingBehaviorReceptor, Melanocortin, Type 4Estrogen Receptor alphaNeurons

• Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females.
  bioRxiv : the preprint server for biology 2023 Babey ME, Krause WC, Herber CB, Chen K, Nikkanen J, Rodriquez R, Zhang X, Castro-Navarro F, Wang Y, Villeda S, Lane NE, Scheller EL, Chan CKF, Ambrosi TH, Ingraham HA
• An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice.
  Science (New York, N.Y.) 2022 Nikkanen J, Leong YA, Krause WC, Dermadi D, Maschek JA, Van Ry T, Cox JE, Weiss EJ, Gokcumen O, Chawla A, Ingraham HA
• Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR-V7 splice variant chromatin binding and transcriptional activities.
  Scientific reports 2022 Basil P, Robertson MJ, Bingman WE, Dash AK, Krause WC, Shafi AA, Piyarathna B, Coarfa C, Weigel NL
• Running the Female Power Grid Across Lifespan Through Brain Estrogen Signaling.
  Annual review of physiology 2021 Ingraham HA, Herber CB, Krause WC
• Oestrogen engages brain MC4R signalling to drive physical activity in female mice.
  Nature 2021 Krause WC, Rodriguez R, Gegenhuber B, Matharu N, Rodriguez AN, Padilla-Roger AM, Toma K, Herber CB, Correa SM, Duan X, Ahituv N, Tollkuhn J, Ingraham HA

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• Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones.
  Nature communications 2019 Herber CB, Krause WC, Wang L, Bayrer JR, Li A, Schmitz M, Fields A, Ford B, Zhang Z, Reid MS, Nomura DK, Nissenson RA, Correa SM, Ingraham HA
• LRH-1 regulates hepatic lipid homeostasis and maintains arachidonoyl phospholipid pools critical for phospholipid diversity.
  JCI insight 2018 Miranda DA, Krause WC, Cazenave-Gassiot A, Suzawa M, Escusa H, Foo JC, Shihadih DS, Stahl A, Fitch M, Nyangau E, Hellerstein M, Wenk MR, Silver DL, Ingraham HA
• Techniques for Evaluation of AR Transcriptional Output and Recruitment to DNA.
  Methods in molecular biology (Clifton, N.J.) 2018 Zhang M, Krause WC, Agoulnik IU
• Origins and Functions of the Ventrolateral VMH: A Complex Neuronal Cluster Orchestrating Sex Differences in Metabolism and Behavior.
  Advances in experimental medicine and biology 2017 Krause WC, Ingraham HA
• Testosterone Rapidly Augments Retrograde Endocannabinoid Signaling in Proopiomelanocortin Neurons to Suppress Glutamatergic Input from Steroidogenic Factor 1 Neurons via Upregulation of Diacylglycerol Lipase-α.
  Neuroendocrinology 2016 Conde K, Fabelo C, Krause WC, Propst R, Goethel J, Fischer D, Hur J, Meza C, Ingraham HA, Wagner EJ
• Sex-dependent changes in metabolism and behavior, as well as reduced anxiety after eliminating ventromedial hypothalamus excitatory output.
  Molecular metabolism 2015 Cheung CC, Krause WC, Edwards RH, Yang CF, Shah NM, Hnasko TS, Ingraham HA
• Androgen receptor and its splice variant, AR-V7, differentially regulate FOXA1 sensitive genes in LNCaP prostate cancer cells.
  The international journal of biochemistry & cell biology 2014 Krause WC, Shafi AA, Nakka M, Weigel NL
• Olfactory memory traces in Drosophila.
  Progress in brain research 2008 Berry J, Krause WC, Davis RL
• GABAA receptor RDL inhibits Drosophila olfactory associative learning.
  Neuron 2007 Liu X, Krause WC, Davis RL
• Repressors of androgen and progesterone receptor action.
  The Journal of biological chemistry 2003 Agoulnik IU, Krause WC, Bingman WE, Rahman HT, Amrikachi M, Ayala GE, Weigel NL