William Byerley, MD
Professor Emeritus
Psychiatry
School of Medicine

Websites

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• Profile at UCSF Department of Psychiatry (psych.ucsf.edu)

Grants and Projects

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• Genetics of Schizophrenia in Oceanic Palau, NIH, 2007-2011
• General Clinical Research Center, NIH, 1977-2011
• High Density Genome Wide Linkage Analysis of 922 Bipolar Families, NIH, 2007-2010
• Collaborative Genomic Study of Bipolar Disorder, NIH, 1998-2009
• Molecular Genetics of Schizophrenia, NIH, 1999-2008
• Admixture Mapping Schizophrenia Genes in Oceanic Palau, NIH, 2003-2008
• Mapping Schizophrenia Genes in Daghestanian Isolates, NIH, 1999-2001
• Molecular Genetics of Schizophrenia, NIH, 1996-2001
• Molecular Genetic of Schizophrena and Manic Depression, NIH, 1993-1998
• Molecular Genetics of Manic Depression, NIH, 1988-1997

Publications (120)

Top publication keywords:
Genetic LinkageMicrosatellite RepeatsChromosomes, Human, Pair 16Genome-Wide Association StudyGenetic MarkersChromosomes, Human, Pair 22Chromosomes, Human, Pair 2Lod ScoreChromosomes, Human, Pair 5Genetic Predisposition to DiseaseChromosome MappingGenome, HumanBipolar DisorderPedigreeSchizophrenia

• Immune, Developmental, and Synaptic Pathways Define Bipolar Disorder Clinical Heterogeneity.
  medRxiv : the preprint server for health sciences 2025 van der Veen T, Tesfaye M, Yang JMK, Boltz T, David FS, Crinion S, Koromina M, Andlauer TFM, Bigdeli TB, Coombes BJ, Greenwood TA, Panagiotaropoulou G, Parker N, Sung H, Bass N, Coleman JRI, Guzman-…
• Genomics yields biological and phenotypic insights into bipolar disorder.
  Nature 2025 O'Connell KS, Koromina M, van der Veen T, Boltz T, David FS, Yang JMK, Lin KH, Wang X, Coleman JRI, Mitchell BL, McGrouther CC, Rangan AV, Lind PA, Koch E, Harder A, Parker N, Bendl J, Adorjan K, …
• BICEP: Bayesian inference for rare genomic variant causality evaluation in pedigrees.
  Briefings in bioinformatics 2024 Ormond C, Ryan NM, Cap M, Byerley W, Corvin A, Heron EA
• Investigating copy number variants in schizophrenia pedigrees using a new consensus pipeline called PECAN.
  Scientific reports 2024 Ormond C, Ryan NM, Byerley W, Heron EA, Corvin A
• Ultrarare Missense Variants Implicated in Utah Pedigrees Multiply Affected With Schizophrenia.
  Biological psychiatry global open science 2023 Ormond C, Ryan NM, Heron EA, Gill M, Byerley W, Corvin A

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• Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
  Nature 2022 Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL,…
• Rare coding variants in ten genes confer substantial risk for schizophrenia.
  Nature 2022 Singh T, Poterba T, Curtis D, Akil H, Al Eissa M, Barchas JD, Bass N, Bigdeli TB, Breen G, Bromet EJ, Buckley PF, Bunney WE, Bybjerg-Grauholm J, Byerley WF, Chapman SB, Chen WJ, Churchhouse C, …
• Characterisation of age and polarity at onset in bipolar disorder.
  The British journal of psychiatry : the journal of mental science 2021 Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, Papiol S, …
• Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
  Nature genetics 2021 Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, …
• Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
  Molecular psychiatry 2019 Bigdeli TB, Genovese G, Georgakopoulos P, Meyers JL, Peterson RE, Iyegbe CO, Medeiros H, Valderrama J, Achtyes ED, Kotov R, Stahl EA, Abbott C, Azevedo MH, Belliveau RA, Bevilacqua E, Bromet EJ, …
• Editorial.
  Molecular neuropsychiatry 2019 Byerley W
• Genome-wide association study identifies 30 loci associated with bipolar disorder.
  Nature genetics 2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, …
• Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder.
  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2018 Budde M, Friedrichs S, Alliey-Rodriguez N, Ament S, Badner JA, Berrettini WH, Bloss CS, Byerley W, Cichon S, Comes AL, Coryell W, Craig DW, Degenhardt F, Edenberg HJ, Foroud T, Forstner AJ, Frank J, …
• Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics.
  International journal of bipolar disorders 2018 Breuer R, Mattheisen M, Frank J, Krumm B, Treutlein J, Kassem L, Strohmaier J, Herms S, Mühleisen TW, Degenhardt F, Cichon S, Nöthen MM, Karypis G, Kelsoe J, Greenwood T, Nievergelt C, Shilling P, …
• Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.
  Nature genetics 2016 Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I,…
• Analysis of Shared Haplotypes amongst Palauans Maps Loci for Psychotic Disorders to 4q28 and 5q23-q31.
  Molecular neuropsychiatry 2016 Bodea CA, Middleton FA, Melhem NM, Klei L, Song Y, Tiobech J, Marumoto P, Yano V, Faraone SV, Roeder K, Myles-Worsley M, Devlin B, Byerley W
• A Rare Variant in CACNA1D Segregates with 7 Bipolar I Disorder Cases in a Large Pedigree.
  Molecular neuropsychiatry 2016 Ross J, Gedvilaite E, Badner JA, Erdman C, Baird L, Matsunami N, Leppert M, Xing J, Byerley W
• Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.
  Human molecular genetics 2016 Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, Baune BT, Bellivier F, Benabarre A, Bengesser S, …
• Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders.
  Microarrays (Basel, Switzerland) 2016 Morgan LZ, Rollins B, Sequeira A, Byerley W, DeLisi LE, Schatzberg AF, Barchas JD, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP
• New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.
  International journal of epidemiology 2015 Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, …
• Characterization of a Novel Mutation in SLC1A1 Associated with Schizophrenia.
  Molecular neuropsychiatry 2015 Afshari P, Myles-Worsley M, Cohen OS, Tiobech J, Faraone SV, Byerley W, Middleton FA
• Characterizing runs of homozygosity and their impact on risk for psychosis in a population isolate.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2014 Melhem NM, Lu C, Dresbold C, Middleton FA, Klei L, Wood S, Faraone SV, Vinogradov S, Tiobech J, Yano V, Roeder K, Byerley W, Myles-Worsley M, Devlin B
• Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex.
  Schizophrenia research 2013 Guella I, Sequeira A, Rollins B, Morgan L, Myers RM, Watson SJ, Akil H, Bunney WE, Delisi LE, Byerley W, Vawter MP
• Heritability and linkage analysis of personality in bipolar disorder.
  Journal of affective disorders 2013 Greenwood TA, Badner JA, Byerley W, Keck PE, McElroy SL, Remick RA, Dessa Sadovnick A, Kelsoe JR
• Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
  Nature genetics 2013 Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F,…
• Heritability and genome-wide SNP linkage analysis of temperament in bipolar disorder.
  Journal of affective disorders 2013 Greenwood TA, Badner JA, Byerley W, Keck PE, McElroy SL, Remick RA, Sadovnick AD, Akiskal HS, Kelsoe JR
• Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2013 Myles-Worsley M, Tiobech J, Browning SR, Korn J, Goodman S, Gentile K, Melhem N, Byerley W, Faraone SV, Middleton FA
• Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.
  The American journal of psychiatry 2012 Fanous AH, Zhou B, Aggen SH, Bergen SE, Amdur RL, Duan J, Sanders AR, Shi J, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, Freedman R, Dudbridge F, Holmans …
• Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2012 Nissen S, Liang S, Shehktman T, Kelsoe JR, Bipolar Genome Study (BiGS), Greenwood TA, Nievergelt CM, McKinney R, Shilling PD, Smith EN, Schork NJ, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, …
• Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.
  Translational psychiatry 2012 Meier S, Mattheisen M, Vassos E, Strohmaier J, Treutlein J, Josef F, Breuer R, Degenhardt F, Mühleisen TW, Müller-Myhsok B, Steffens M, Schmael C, McMahon FJ, Bipolar Disorder Genome Study (BiGS) …
• Detection of identity by descent using next-generation whole genome sequencing data.
  BMC bioinformatics 2012 Su SY, Kasberger J, Baranzini S, Byerley W, Liao W, Oksenberg J, Sherr E, Jorgenson E
• Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
  Molecular psychiatry 2012 Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ, Gershon ES, Kelsoe JR, Greenwood TA, Nievergelt CM, Chen C, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, Nurnberger JI, Edenberg HJ…
• Copy number variants for schizophrenia and related psychotic disorders in Oceanic Palau: risk and transmission in extended pedigrees.
  Biological psychiatry 2011 Melhem N, Middleton F, McFadden K, Klei L, Faraone SV, Vinogradov S, Tiobech J, Yano V, Kuartei S, Roeder K, Byerley W, Devlin B, Myles-Worsley M
• Strategies to identify genes for complex disorders: a focus on bipolar disorder and chromosome 16p.
  Psychiatric genetics 2011 Byerley W, Badner JA
• Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms.
  Molecular psychiatry 2011 Badner JA, Koller D, Foroud T, Edenberg H, Nurnberger JI, Zandi PP, Willour VL, McMahon FJ, Potash JB, Hamshere M, Grozeva D, Green E, Kirov G, Jones I, Jones L, Craddock N, Morris D, Segurado R, Gill…
• Lack of association to a NRG1 missense polymorphism in schizophrenia or bipolar disorder in a Costa Rican population.
  Schizophrenia research 2011 Moon E, Rollins B, Mesén A, Sequeira A, Myers RM, Akil H, Watson SJ, Barchas J, Jones EG, Schatzberg A, Bunney WE, DeLisi LE, Byerley W, Vawter MP
• Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.
  PLoS genetics 2011 Smith EN, Koller DL, Panganiban C, Szelinger S, Zhang P, Badner JA, Barrett TB, Berrettini WH, Bloss CS, Byerley W, Coryell W, Edenberg HJ, Foroud T, Gershon ES, Greenwood TA, Guo Y, Hipolito M, …
• Familial transmission of schizophrenia in Palau: A 20-year genetic epidemiological study in three generations.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011 Myles-Worsley M, Tiobech J, Blailes F, Middleton FA, Vinogradov S, Byerley W, Faraone SV
• Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications.
  The American journal of psychiatry 2011 Levinson DF, Duan J, Oh S, Wang K, Sanders AR, Shi J, Zhang N, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, Kendler KS, Freedman R, Dudbridge F, Pe'er I, …
• The Internet-based MGS2 control sample: self report of mental illness.
  The American journal of psychiatry 2010 Sanders AR, Levinson DF, Duan J, Dennis JM, Li R, Kendler KS, Rice JP, Shi J, Mowry BJ, Amin F, Silverman JM, Buccola NG, Byerley WF, Black DW, Freedman R, Cloninger CR, Gejman PV
• Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation.
  BMC medical genomics 2009 Martin MV, Rollins B, Sequeira PA, Mesén A, Byerley W, Stein R, Moon EA, Akil H, Jones EG, Watson SJ, Barchas J, DeLisi LE, Myers RM, Schatzberg A, Bunney WE, Vawter MP
• Common variants on chromosome 6p22.1 are associated with schizophrenia.
  Nature 2009 Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I, Dudbridge F, Holmans PA, Whittemore AS, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, Crowe RR, …
• Genome-wide association study of bipolar disorder in European American and African American individuals.
  Molecular psychiatry 2009 Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E, Greenwood TA, Hipolito M, Koller DL, Lawson WB, Liu C, …
• Neuropsychological performance as endophenotypes in extended schizophrenia families from the Central Valley of Costa Rica.
  Psychiatric genetics 2009 Bertisch H, Mesen-Fainardi A, Martin MV, Pérez-Vargas V, Vargas-Rodríguez T, Delgado G, Delgado C, Llach M, LaPrade B, Byerley W, Bunney WE, Vawter MP, DeLisi LE, Pritzker Neuropsychiatric Research …
• Meta-analysis of 32 genome-wide linkage studies of schizophrenia.
  Molecular psychiatry 2008 Ng MY, Levinson DF, Faraone SV, Suarez BK, DeLisi LE, Arinami T, Riley B, Paunio T, Pulver AE, Holmans PA, Escamilla M, Wildenauer DB, Williams NM, Laurent C, Mowry BJ, Brzustowicz LM, Maziade M, …
• Singleton deletions throughout the genome increase risk of bipolar disorder.
  Molecular psychiatry 2008 Zhang D, Cheng L, Qian Y, Alliey-Rodriguez N, Kelsoe JR, Greenwood T, Nievergelt C, Barrett TB, McKinney R, Schork N, Smith EN, Bloss C, Nurnberger J, Edenberg HJ, Foroud T, Sheftner W, Lawson WB, …
• Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder.
  Psychiatric genetics 2008 Liu L, Foroud T, Xuei X, Berrettini W, Byerley W, Coryell W, El-Mallakh R, Gershon ES, Kelsoe JR, Lawson WB, MacKinnon DF, McInnis M, McMahon FJ, Murphy DL, Rice J, Scheftner W, Zandi PP, Lohoff FW, …
• Identification of loci associated with schizophrenia by genome-wide association and follow-up.
  Nature genetics 2008 O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, Leung HT, Hartmann AM, Möller…
• Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20.
  Psychiatric genetics 2008 Ross J, Berrettini W, Coryell W, Gershon ES, Badner JA, Kelsoe JR, McInnis MG, McMahon FJ, Murphy DL, Nurnberger JI, Foroud T, Rice JP, Scheftner WB, Zandi P, Edenberg H, Byerley W
• Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees.
  Bipolar disorders 2008 Payne JL, MacKinnon DF, Mondimore FM, McInnis MG, Schweizer B, Zamoiski RB, McMahon FJ, Nurnberger JI, Rice JP, Scheftner W, Coryell W, Berrettini WH, Kelsoe JR, Byerley W, Gershon ES, DePaulo JR, …
• No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics.
  The American journal of psychiatry 2008 Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, Burrell GJ, Rice JP, Nertney DA, Olincy A, Rozic P, Vinogradov S, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, …
• Genetic liability to schizophrenia in Oceanic Palau: a search in the affected and maternal generation.
  Human genetics 2007 Devlin B, Klei L, Myles-Worsley M, Tiobech J, Otto C, Byerley W, Roeder K
• Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33.
  The American journal of psychiatry 2007 Goes FS, Zandi PP, Miao K, McMahon FJ, Steele J, Willour VL, Mackinnon DF, Mondimore FM, Schweizer B, Nurnberger JI, Rice JP, Scheftner W, Coryell W, Berrettini WH, Kelsoe JR, Byerley W, Murphy DL, …
• Genome scans and gene expression microarrays converge to identify gene regulatory loci relevant in schizophrenia.
  Human genetics 2006 Vawter MP, Atz ME, Rollins BL, Cooper-Casey KM, Shao L, Byerley WF
• Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.
  American journal of human genetics 2006 Suarez BK, Duan J, Sanders AR, Hinrichs AL, Jin CH, Hou C, Buccola NG, Hale N, Weilbaecher AN, Nertney DA, Olincy A, Green S, Schaffer AW, Smith CJ, Hannah DE, Rice JP, Cox NJ, Martinez M, Mowry BJ, …
• Evidence of association between bipolar disorder and Citron on chromosome 12q24.
  Molecular psychiatry 2005 Lyons-Warren A, Chang JJ, Balkissoon R, Kamiya A, Garant M, Nurnberger J, Scheftner W, Reich T, McMahon F, Kelsoe J, Gershon E, Coryell W, Byerley W, Berrettini W, Depaulo R, McInnis M, Sawa A
• Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.
  American journal of human genetics 2005 McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly …
• Suggestive linkage of schizophrenia to 5p13 in Costa Rica.
  Molecular psychiatry 2005 Cooper-Casey K, Mésen-Fainardi A, Galke-Rollins B, Llach M, Laprade B, Rodriguez C, Riondet S, Bertheau A, Byerley W
• Linkage analysis of a completely ascertained sample of familial schizophrenics and bipolars from Palau, Micronesia.
  Human genetics 2005 Klei L, Bacanu SA, Myles-Worsley M, Galke B, Xie W, Tiobech J, Otto C, Roeder K, Devlin B, Byerley W
• Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin.
  Nature genetics 2004 Cichon S, Buervenich S, Kirov G, Akula N, Dimitrova A, Green E, Schumacher J, Klopp N, Becker T, Ohlraun S, Schulze TG, Tullius M, Gross MM, Jones L, Krastev S, Nikolov I, Hamshere M, Jones I, Czerski…
• Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees.
  Biological psychiatry 2004 Schulze TG, Buervenich S, Badner JA, Steele CJ, Detera-Wadleigh SD, Dick D, Foroud T, Cox NJ, MacKinnon DF, Potash JB, Berrettini WH, Byerley W, Coryell W, DePaulo JR, Gershon ES, Kelsoe JR, McInnis …
• Microarray screening of lymphocyte gene expression differences in a multiplex schizophrenia pedigree.
  Schizophrenia research 2004 Vawter MP, Ferran E, Galke B, Cooper K, Bunney WE, Byerley W
• Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia.
  American journal of human genetics 2003 Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I, Williams NM, Schwab SG, Pulver AE, Faraone SV, Brzustowicz LM, Kaufmann CA, Garver DL, Gurling HM, Lindholm E, Coon H, Moises HW, …
• Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.
  American journal of human genetics 2003 Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI, Craddock N, DePaulo JR, Baron M, Gershon ES, Ekholm J, Cichon S, Turecki G, Claes S, Kelsoe JR, Schofield PR, Badenhop RF,…
• Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative.
  American journal of human genetics 2003 Dick DM, Foroud T, Flury L, Bowman ES, Miller MJ, Rau NL, Moe PR, Samavedy N, El-Mallakh R, Manji H, Glitz DA, Meyer ET, Smiley C, Hahn R, Widmark C, McKinney R, Sutton L, Ballas C, Grice D, …
• Genome-wide scan for linkage to schizophrenia in a Spanish-origin cohort from Costa Rica.
  American journal of medical genetics 2002 DeLisi LE, Mesen A, Rodriguez C, Bertheau A, LaPrade B, Llach M, Riondet S, Razi K, Relja M, Byerley W, Sherrington R
• Genome-wide multipoint linkage analyses of multiplex schizophrenia pedigrees from the oceanic nation of Palau.
  Molecular psychiatry 2002 Devlin B, Bacanu SA, Roeder K, Reimherr F, Wender P, Galke B, Novasad D, Chu A, TCuenco K, Tiobek S, Otto C, Byerley W
• Genome-wide distribution of linkage disequilibrium in the population of Palau and its implications for gene flow in Remote Oceania.
  Human genetics 2001 Devlin B, Roeder K, Otto C, Tiobech S, Byerley W
• Ocular motor delayed-response task performance among patients with schizophrenia and their biological relatives.
  Psychophysiology 2001 McDowell JE, Brenner CA, Myles-Worsley M, Coon H, Byerley W, Clementz BA
• Mutation screening of a neutral amino acid transporter, ASCT1, and its potential role in schizophrenia.
  Psychiatric genetics 2000 Bennett PJ, Hoff M, Rosenthal J, Zhao M, Coon H, Myles-Worsley M, Byerley WF
• The ascertainment of multiplex schizophrenia pedigrees from Daghestan genetic isolates (Northern Caucasus, Russia).
  Psychiatric genetics 2000 Bulayeva KB, Leal SM, Pavlova TA, Kurbanov R, Coover S, Bulayev O, Byerley W
• Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families.
  American journal of medical genetics 1999 Myles-Worsley M, Coon H, McDowell J, Brenner C, Hoff M, Lind B, Bennett P, Freedman R, Clementz B, Byerley W
• Tests for linkage to MDI with a new trinucleotide repeat polymorphism in the 80K-H gene on chromosome 19.
  Psychiatric genetics 1999 Bennett P, Coon H, Lenox RH, Hoff M, Rosenthal J, Byerley W
• Genetic epidemiological study of schizophrenia in Palau, Micronesia: prevalence and familiality.
  American journal of medical genetics 1999 Myles-Worsley M, Coon H, Tiobech J, Collier J, Dale P, Wender P, Reimherr F, Polloi A, Byerley W
• Measuring liability for schizophrenia using optimized antisaccade stimulus parameters.
  Psychophysiology 1999 McDowell JE, Myles-Worsley M, Coon H, Byerley W, Clementz BA
• Evidence for a chromosome 2p13-14 schizophrenia susceptibility locus in families from Palau, Micronesia.
  Molecular psychiatry 1998 Coon H, Myles-Worsley M, Tiobech J, Hoff M, Rosenthal J, Bennett P, Reimherr F, Wender P, Dale P, Polloi A, Byerley W
• The sensitivity of the Spontaneous Selective Attention Test (SSAT): a study of schizophrenic inpatients and outpatients versus normal controls.
  Schizophrenia research 1998 Myles-Worsley M, Coon H, Byerley W
• Analysis of chromosome 6 markers in eight Utah schizophrenia pedigrees.
  Psychiatric genetics 1998 Lind B, Hoff M, Rosenthal J, Byerley W, Coon H
• Search for a schizophrenia susceptibility gene on chromosome 13.
  Psychiatric genetics 1998 Jensen J, Coon H, Hoff M, Rosenthal J, Reimherr F, Wender P, Myles-Worsley M, Freedman R, Byerley W
• Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, Young DA, Breese CR, Adams C, …
• Evidence of linkage disequilibrium between schizophrenia and the SCa1 CAG repeat on chromosome 6p23.
  American journal of human genetics 1996 Wang S, Detera-Wadleigh SD, Coon H, Sun CE, Goldin LR, Duffy DL, Byerley WF, Gershon ES, Diehl SR
• Analysis of chromosome 18 DNA markers in multiplex pedigrees with manic depression.
  Biological psychiatry 1996 Coon H, Hoff M, Holik J, Hadley D, Fang N, Reimherr F, Wender P, Byerley W
• A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22).
  American journal of medical genetics 1996 Gill M, Vallada H, Collier D, Sham P, Holmans P, Murray R, McGuffin P, Nanko S, Owen M, Antonarakis S, Housman D, Kazazian H, Nestadt G, Pulver AE, Straub RE, MacLean CJ, Walsh D, Kendler KS, DeLisi L…
• Genotype-to-phenotype analysis: search for clinical characteristics of a missense change in the GABAA-beta 1 receptor gene.
  American journal of medical genetics 1996 Sobell JL, Sigurdson DC, Heston LL, Byerley WF, Sommer SS
• Developmental and genetic influences on the P50 sensory gating phenotype.
  Biological psychiatry 1996 Myles-Worsley M, Coon H, Byerley W, Waldo M, Young D, Freedman R
• Anticipation in multiplex schizophrenia pedigrees.
  Psychiatric genetics 1996 Yaw J, Myles-Worsley M, Hoff M, Holik J, Freedman R, Byerley W, Coon H
• Nicotinic receptor function in schizophrenia.
  Schizophrenia bulletin 1996 Leonard S, Adams C, Breese CR, Adler LE, Bickford P, Byerley W, Coon H, Griffith JM, Miller C, Myles-Worsley M, Nagamoto HT, Rollins Y, Stevens KE, Waldo M, Freedman R
• Sensory gating deficits in parents of schizophrenics.
  American journal of medical genetics 1995 Waldo M, Myles-Worsley M, Madison A, Byerley W, Freedman R
• An international two-stage genome-wide search for schizophrenia susceptibility genes.
  Nature genetics 1995 Moises HW, Yang L, Kristbjarnarson H, Wiese C, Byerley W, Macciardi F, Arolt V, Blackwood D, Liu X, Sjögren B
• Search for a gene predisposing to manic-depression on chromosome 21.
  American journal of medical genetics 1995 Byerley W, Holik J, Hoff M, Coon H
• Genetic mapping of adrenergic receptor genes in humans.
  Journal of molecular medicine (Berlin, Germany) 1995 Hoehe MR, Otterud B, Hsieh WT, Martinez MM, Stauffer D, Holik J, Berrettini WH, Byerley WF, Gershon ES, Lalouel JM
• Manic-depression and the norepinephrine transporter gene.
  Human heredity 1995 Hadley D, Hoff M, Holik J, Reimherr F, Wender P, Coon H, Byerley W
• Temperature gradient gel electrophoresis analysis of the beta-NGF gene in schizophrenia.
  Journal of psychiatry & neuroscience : JPN 1995 Khan AS, Freedman R, Byerley W, Leonard S
• Mutation scan of the D1 dopamine receptor gene in 22 cases of bipolar I disorder.
  American journal of medical genetics 1995 Shah M, Coon H, Holik J, Hoff M, Helmer V, Panos P, Byerley W
• 1995 Park City Molecular Psychiatry Conference, 5-8 February 1995, Park City, Utah.
  Psychiatric genetics 1995 Nurnberger JI, Byerley WF
• Linkage analysis between schizophrenia and index simple-sequence repeat loci for chromosome 21.
  Human heredity 1995 Byerley W, Hoff M, Holik J, Myles-Worsley M, Waldo M, Freedman R, Coon H
• Schizophrenia and GABAA receptor subunit genes.
  Psychiatric genetics 1995 Byerley W, Bailey ME, Hicks AA, Riley BP, Darlison MG, Holik J, Hoff M, Umar F, Reimherr F, Wender P
• Dinucleotide repeat polymorphism in the human taurine transporter gene (TAUT).
  Human molecular genetics 1994 Gregor P, Hoff M, Holik J, Hadley D, Fang N, Coon H, Byerley W
• Schizophrenia and nicotinic receptors.
  Harvard review of psychiatry 1994 Freedman R, Adler LE, Bickford P, Byerley W, Coon H, Cullum CM, Griffith JM, Harris JG, Leonard S, Miller C
• SSCP at the HTR1DA locus.
  Human molecular genetics 1994 Kasapi M, Holik J, Shah M, Hoff M, Coon H, Byerley W
• Search for a schizophrenia susceptibility locus on human chromosome 22.
  American journal of medical genetics 1994 Polymeropoulos MH, Coon H, Byerley W, Gershon ES, Goldin L, Crow TJ, Rubenstein J, Hoff M, Holik J, Smith AM
• Analysis of chromosome 22 markers in nine schizophrenia pedigrees.
  American journal of medical genetics 1994 Coon H, Holik J, Hoff M, Reimherr F, Wender P, Myles-Worsley M, Waldo M, Freedman R, Byerley W
• A linkage study with D5 dopamine and alpha 2C-adrenergic receptor genes in six multiplex bipolar pedigrees.
  Psychiatric genetics 1994 Byerley W, Hoff M, Holik J, Coon H
• Linkage analysis between schizophrenia and a microsatellite polymorphism for the D5 dopamine receptor gene.
  Psychiatric genetics 1994 Ravindranathan A, Coon H, DeLisi L, Holik J, Hoff M, Brown A, Shields G, Crow T, Byerley W
• Schizophrenia and glutamate receptor genes.
  Psychiatric genetics 1994 Pariseau C, Gregor P, Myles-Worsley M, Holik J, Hoff M, Waldo M, Freedman R, Coon H, Byerley W
• Human dopamine transporter gene not linked to schizophrenia in multigenerational pedigrees.
  Human heredity 1993 Byerley W, Coon H, Hoff M, Holik J, Waldo M, Freedman R, Caron MG, Giros B
• Use of a neurophysiological trait in linkage analysis of schizophrenia.
  Biological psychiatry 1993 Coon H, Plaetke R, Holik J, Hoff M, Myles-Worsley M, Waldo M, Freedman R, Byerley W
• Dinucleotide repeat polymorphism in the 3' untranslated region of an anonymous brain cDNA mapping to chromosome 2 (D2S230).
  Human molecular genetics 1993 Byerley W, Khan AS, Holik J, Hoff M, Sikela JM
• A genome-wide search for genes predisposing to manic-depression, assuming autosomal dominant inheritance.
  American journal of human genetics 1993 Coon H, Jensen S, Hoff M, Holik J, Plaetke R, Reimherr F, Wender P, Leppert M, Byerley W
• VNTR polymorphism for the human dopamine transporter gene (DAT1).
  Human molecular genetics 1993 Byerley W, Hoff M, Holik J, Caron MG, Giros B
• Linkage analysis of schizophrenia with five dopamine receptor genes in nine pedigrees.
  American journal of human genetics 1993 Coon H, Byerley W, Holik J, Hoff M, Myles-Worsley M, Lannfelt L, Sokoloff P, Schwartz JC, Waldo M, Freedman R
• Genetic linkage of the human gene for phenylethanolamine N-methyltransferase (PNMT), the adrenaline-synthesizing enzyme, to DNA markers on chromosome 17q21-q22.
  Human molecular genetics 1992 Hoehe MR, Plaetke R, Otterud B, Stauffer D, Holik J, Byerley WF, Baetge EE, Gershon ES, Lalouel JM, Leppert M
• Tyrosine hydroxylase gene not linked to manic-depression in seven of eight pedigrees.
  Human heredity 1992 Byerley W, Plaetke R, Hoff M, Jensen S, Holik J, Reimherr F, Mellon C, Wender P, O'Connell P, Leppert M
• Codistribution of a sensory gating deficit and schizophrenia in multi-affected families.
  Psychiatry research 1991 Waldo MC, Carey G, Myles-Worsley M, Cawthra E, Adler LE, Nagamoto HT, Wender P, Byerley W, Plaetke R, Freedman R
• Drug therapy: The diagnosis and management of insomnia.
  The New England journal of medicine 1990 Gillin JC, Byerley WF
• Schizophrenia. Genetic linkage revisited.
  Nature 1989 Byerley WF
• Strategies for linkage studies in schizophrenia.
  Schizophrenia research 1989 Mellon CD, Byerley WF
• Mapping genes for manic-depression and schizophrenia with DNA markers.
  Trends in neurosciences 1989 Byerley W, Mellon C, O'Connell P, Lalouel JM, Nakamura Y, Leppert M, White R
• Biological effect of bright light.
  Progress in neuro-psychopharmacology & biological psychiatry 1989 Byerley WF, Risch SC, Gillin JC, Janowsky DS, Parker D, Rossman LG, Kripke DF
• The effect of bright light on plasma prolactin.
  Biological psychiatry 1988 Byerley WF, Risch SC, Jachna J, Onstott P, Kripke DF