William Arnold, PhD
Postdoctoral Scholar
Biochemistry and Biophysics
School of Medicine

Publications (14)

Top publication keywords:
Antibiotics, AntineoplasticDopamineSerotoninCardiotoxicityArachidonic AcidReceptor, Cannabinoid, CB2EndocannabinoidsLinoleic AcidDocosahexaenoic AcidsCannabinoidsDoxorubicinCytochrome P-450 Enzyme SystemReceptor, Cannabinoid, CB1Anti-Inflammatory AgentsEicosapentaenoic Acid

• Structural basis of TRPV1 modulation by endogenous bioactive lipids.
  bioRxiv : the preprint server for biology 2023 Arnold WR, Mancino A, Moss FR, Frost A, Julius D, Cheng Y
• Classifying liganded states in heterogeneous single-particle cryo-EM datasets.
  Microscopy (Oxford, England) 2022 Arnold WR, Asarnow D, Cheng Y
• Anthracycline derivatives inhibit cardiac CYP2J2.
  Journal of inorganic biochemistry 2022 Kim JS, Arango AS, Shah S, Arnold WR, Tajkhorshid E, Das A
• Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel.
  Nature communications 2021 Arnold WR, Carnevale LN, Xie Z, Baylon JL, Tajkhorshid E, Hu H, Das A
• CYP2J2 Molecular Recognition: A New Axis for Therapeutic Design.
  Pharmacology & therapeutics 2020 Das A, Weigle AT, Arnold WR, Kim JS, Carnevale LN, Huff HC

Show all (9 more) Hide

• Polymorphisms of CYP2C8 Alter First-Electron Transfer Kinetics and Increase Catalytic Uncoupling.
  International journal of molecular sciences 2019 R Arnold W, Zelasko S, D Meling D, Sam K, Das A
• Endocannabinoid Virodhamine Is an Endogenous Inhibitor of Human Cardiovascular CYP2J2 Epoxygenase.
  Biochemistry 2018 Carnevale LN, Arango AS, Arnold WR, Tajkhorshid E, Das A
• An Emerging Pathway of Doxorubicin Cardiotoxicity Mediated through CYP2J2.
  Biochemistry 2018 Arnold WR, Das A
• Cross-talk of cannabinoid and endocannabinoid metabolism is mediated via human cardiac CYP2J2.
  Journal of inorganic biochemistry 2018 Arnold WR, Weigle AT, Das A
• Arachidonic Acid Metabolism by Human Cardiovascular CYP2J2 Is Modulated by Doxorubicin.
  Biochemistry 2017 Arnold WR, Baylon JL, Tajkhorshid E, Das A
• Heterologous expression and characterization of plant Taxadiene-5α-Hydroxylase (CYP725A4) in Escherichia coli.
  Protein expression and purification 2017 Rouck JE, Biggs BW, Kambalyal A, Arnold WR, De Mey M, Ajikumar PK, Das A
• Asymmetric Binding and Metabolism of Polyunsaturated Fatty Acids (PUFAs) by CYP2J2 Epoxygenase.
  Biochemistry 2016 Arnold WR, Baylon JL, Tajkhorshid E, Das A
• Substrate binding to cytochrome P450-2J2 in Nanodiscs detected by nanoplasmonic Lycurgus cup arrays.
  Biosensors & bioelectronics 2015 Plucinski L, Ranjan Gartia M, Arnold WR, Ameen A, Chang TW, Hsiao A, Logan Liu G, Das A
• Endocannabinoid metabolism by cytochrome P450 monooxygenases.
  Prostaglandins & other lipid mediators 2014 Zelasko S, Arnold WR, Das A