Wenlong Xia, PhD
Assistant Researcher
Neurology
School of Medicine

Publications (6)

Top publication keywords:
TOR Serine-Threonine KinasesUbiquitin-Protein LigasesMyelin SheathSpinal CordOligodendrogliaBrain InjuriesAstrocytesInduced Pluripotent Stem CellsLysosomesInterleukinsOligodendrocyte Precursor CellsWhite MatterCell DifferentiationExosomesCentral Nervous System

• Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain.
  Nature neuroscience 2024 Chen J, Crouch EE, Zawadzki ME, Jacobs KA, Mayo LN, Choi JJ, Lin PY, Shaikh S, Tsui J, Gonzalez-Granero S, Waller S, Kelekar A, Kang G, Valenzuela EJ, Birrueta JO, Diafos LN, Wedderburn-Pugh K, Di …
• mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes.
  Journal of neuroinflammation 2024 Leng K, Rooney B, McCarthy F, Xia W, Rose IVL, Bax S, Chin M, Fathi S, Herrington KA, Leonetti M, Kao A, Fancy SPJ, Elias JE, Kampmann M
• Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling.
  Cell reports 2023 Hoi KK, Xia W, Wei MM, Ulloa Navas MJ, Garcia Verdugo JM, Nachury MV, Reiter JF, Fancy SPJ
• CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states.
  Nature neuroscience 2022 Leng K, Rose IVL, Kim H, Xia W, Romero-Fernandez W, Rooney B, Koontz M, Li E, Ao Y, Wang S, Krawczyk M, Tcw J, Goate A, Zhang Y, Ullian EM, Sofroniew MV, Fancy SPJ, Schrag MS, Lippmann ES, Kampmann M
• Mechanisms of oligodendrocyte progenitor developmental migration.
  Developmental neurobiology 2021 Xia W, Fancy SPJ
• Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation.
  Neuron 2021 Niu J, Yu G, Wang X, Xia W, Wang Y, Hoi KK, Mei F, Xiao L, Chan JR, Fancy SPJ