Wendy Xin, PhD
Postdoctoral Scholar
Neurology
School of Medicine

Awards

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• NARSAD Young Investigator Grant, Brain & Behavior Research Foundation, 2024-2026
• K99/R00 Pathway to Independence Award, NINDS, 2023-2028
• Ruth L. Kirschstein National Research Service Award (F32), NINDS, 2020-2022
• Graduate Research Fellowship, National Science Foundation, 2013-2016

Education & Training

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• PhD Neuroscience Johns Hopkins University School of Medicine 12/2018
• BSc Neuroscience University of Toronto 06/2012

Websites

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• @@Dr_Oligo on Twitter (twitter.com)
• LinkedIn Profile (linkedin.com)
• Personal Website (oligodendrocyte.org)
• Twitter (twitter.com)

Publications (13)

Top publication keywords:
Ventral Tegmental AreaAstrocytesMultiple SclerosisOligodendrogliaGlutamineDopaminergic NeuronsNeuronal PlasticityMemoryMyelin SheathDemyelinating DiseasesGABAergic NeuronsMesencephalonLearningGlutamate-Ammonia LigaseReceptors, Dopamine D2

• Adolescent oligodendrogenesis and myelination restrict experience-dependent neuronal plasticity in adult visual cortex.
  bioRxiv : the preprint server for biology 2023 Xin W, Kaneko M, Roth RH, Zhang A, Nocera S, Ding JB, Stryker MP, Chan JR
• Validating visual evoked potentials as a preclinical, quantitative biomarker for remyelination efficacy.
  Brain : a journal of neurology 2022 Cordano C, Sin JH, Timmons G, Yiu HH, Stebbins K, Guglielmetti C, Cruz-Herranz A, Xin W, Lorrain D, Chan JR, Green AJ
• Motor learning revamps the myelin landscape.
  Nature neuroscience 2022 Xin W, Chan JR
• Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice.
  Scientific reports 2021 Sell GL, Xin W, Cook EK, Zbinden MA, Schaffer TB, O'Meally RN, Cole RN, Margolis SS
• Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer's disease.
  Neuron 2021 Chen JF, Liu K, Hu B, Li RR, Xin W, Chen H, Wang F, Chen L, Li RX, Ren SY, Xiao L, Chan JR, Mei F

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• TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells.
  eLife 2021 Chang KJ, Agrawal I, Vainshtein A, Ho WY, Xin W, Tucker-Kellogg G, Susuki K, Peles E, Ling SC, Chan JR
• Myelin plasticity: sculpting circuits in learning and memory.
  Nature reviews. Neuroscience 2020 Xin W, Chan JR
• Control of food approach and eating by a GABAergic projection from lateral hypothalamus to dorsal pons.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Marino RAM, McDevitt RA, Gantz SC, Shen H, Pignatelli M, Xin W, Wise RA, Bonci A
• That Wasn't a Complement-Too Much C3 in Demyelinating Disease.
  Immunity 2020 Xin W, Chan JR
• Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase.
  Cell reports 2019 Xin W, Mironova YA, Shen H, Marino RAM, Waisman A, Lamers WH, Bergles DE, Bonci A
• Ventral midbrain astrocytes display unique physiological features and sensitivity to dopamine D2 receptor signaling.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2018 Xin W, Schuebel KE, Jair KW, Cimbro R, De Biase LM, Goldman D, Bonci A
• Functional Astrocyte Heterogeneity and Implications for Their Role in Shaping Neurotransmission.
  Frontiers in cellular neuroscience 2018 Xin W, Bonci A
• VTA dopamine neuron plasticity - the unusual suspects.
  The European journal of neuroscience 2016 Xin W, Edwards N, Bonci A