Warner Greene, MD, PhD
Professor
Medicine
School of Medicine

Dr. Greene is a member of the Institute of Medicine of the National Academies and a fellow of the American Academy for the Advancement of Science. He also serves as Co-Director of the UCSF-Gladstone Center for AIDS Research, and has served as a Councilor and President of the Association of American Physicians. Dr. Greene earned a bachelor’s degree at Stanford University and an MD/PhD at Washington University School of Medicine. He took his internship and residency training in Medicine at the Massachusetts General Hospital at Harvard. After serving as a Senior Investigator at the National Cancer Institute and a Professor of Medicine and Howard Hughes Investigator at Duke University Medical Center, Dr. Greene accepted his current position as the Founding Director of the Gladstone Institute of Virology and Immunology in 1991. The ongoing research in Dr. Greene’s laboratory focuses on the molecular mechanisms underlying HIV pathogenesis, latency, and transmission. He is the author of more than 380 scientific papers and has been recognized as one of the 100 Most Cited Scientists in the world. In 2007, Dr. Greene expanded his work to include global health in sub-Saharan Africa in his service as president and executive chairman of the Accordia Global Health Foundation. Accordia established the Infectious Diseases Institute at Makerere University in Uganda, which has trained thousands of African health care workers, is caring for 30,000 HIV-infected patients, and has brought health care to nearly 500,000 people living in remote rural regions of Uganda. In 2016, Accordia merged with Africare.

• Infectious Diseases Institute at Makerere University College of Health Sciences: a case study of a sustainable capacity building model for health care, research and training.
  African health sciences 2022 Nakanjako D, Castelnuovo B, Sewankambo N, Kakaire T, Brough RL, Katabira ET, Thomas DL, Quinn TC, Colebunders R, Greene WC, Ronald AR, Coutinho A, McAdam K, Serwadda D, Wabwire-Mangen F, Katongole-…
• Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy.
  Nature communications 2022 Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J,…
• Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination.
  JCI insight 2022 Matsui Y, Li L, Prahl M, Cassidy AG, Ozarslan N, Golan Y, Gonzalez VJ, Lin CY, Jigmeddagva U, Chidboy MA, Montano M, Taha TY, Khalid MM, Sreekumar B, Hayashi JM, Chen PY, Kumar GR, Warrier L, Wu AH, …
• Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq.
  Frontiers in immunology 2022 Luo X, Frouard J, Zhang G, Neidleman J, Xie G, Sheedy E, Roan NR, Greene WC
• Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination.
  Nature 2022 Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, …
• Limited Cross-Variant Immunity after Infection with the SARS-CoV-2 Omicron Variant Without Vaccination.
  medRxiv : the preprint server for health sciences 2022 Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, …
• Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals.
  Frontiers in immunology 2022 George AF, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, Shin MG, Lee MJ, Blish CA, Deeks SG, Greene WC, Lee SA, Roan NR
• Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy.
  Research square 2021 Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J,…
• Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy.
  medRxiv : the preprint server for health sciences 2021 Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J,…
• Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C-C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status.
  Frontiers in microbiology 2021 Pedersen JG, Egedal JH, Packard TA, Thavachelvam K, Xie G, van der Sluis RM, Greene WC, Roan NR, Jakobsen MR
• SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy.
  bioRxiv : the preprint server for biology 2021 Ryu JK, Sozmen EG, Dixit K, Montano M, Matsui Y, Liu Y, Helmy E, Deerinck TJ, Yan Z, Schuck R, Acevedo RM, Spencer CM, Thomas R, Pico AR, Zamvil SS, Lynch KL, Ellisman MH, Greene WC, Akassoglou K
• mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status.
  eLife 2021 Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR
• Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission.
  The Journal of biological chemistry 2021 Luo X, Mouquet H, Schwartz O, Greene WC
• mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status.
  bioRxiv : the preprint server for biology 2021 Neidleman J, Luo X, McGregor M, Xie G, Murray V, Greene WC, Lee SA, Roan NR
• Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19.
  Cell reports 2021 Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee SA, Ghosn E, Lynch KL, Roan NR
• Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection.
  Mucosal immunology 2021 Egedal JH, Xie G, Packard TA, Laustsen A, Neidleman J, Georgiou K, Pillai SK, Greene WC, Jakobsen MR, Roan NR
• Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo.
  Cell reports 2021 Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR
• Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19.
  medRxiv : the preprint server for health sciences 2021 Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee S, Ghosn E, Lynch K, Roan NR
• Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo.
  Journal of virology 2021 Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F,…
• Identification of unrecognized host factors promoting HIV-1 latency.
  PLoS pathogens 2020 Li Z, Hajian C, Greene WC
• Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals.
  PLoS pathogens 2020 Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA
• Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir.
  eLife 2020 Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA,…
• SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential.
  Cell reports. Medicine 2020 Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR
• SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential.
  bioRxiv : the preprint server for biology 2020 Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George A, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR
• HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread.
  eLife 2020 Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR
• Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
  PLoS pathogens 2020 Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR
• Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling.
  Human reproduction (Oxford, England) 2020 George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR
• Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy.
  Viruses 2020 Schwarzer R, Gramatica A, Greene WC
• HIV-2 Depletes CD4 T Cells through Pyroptosis despite Vpx-Dependent Degradation of SAMHD1.
  Journal of virology 2019 Luo X, Herzig E, Doitsh G, Grimmett ZW, Muñoz-Arias I, Greene WC
• Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency.
  Retrovirology 2019 Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA
• Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform.
  Cell 2019 Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC
• Tissue microenvironment initiates an immune response to structural components of Staphylococcus aureus.
  Experimental dermatology 2019 Mainzer C, Packard T, Bordes S, Closs B, Greene WC, Elias PM, Uchida Y
• Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes.
  Cytokine 2018 Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE
• Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma.
  Biology of reproduction 2018 Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR
• Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells.
  eLife 2018 Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E
• Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells.
  Cell reports 2017 Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR
• Semen amyloids participate in spermatozoa selection and clearance.
  eLife 2017 Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, …
• SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency.
  Cell host & microbe 2017 Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M
• Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.
  Nature 2017 Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC
• Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.
  PLoS pathogens 2017 Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, …
• The mTOR Complex Controls HIV Latency.
  Cell host & microbe 2016 Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman …
• Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation.
  Nature medicine 2016 Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK
• Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection.
  The Journal of biological chemistry 2016 LoRicco JG, Xu CS, Neidleman J, Bergkvist M, Greene WC, Roan NR, Makhatadze GI
• Dissecting How CD4 T Cells Are Lost During HIV Infection.
  Cell host & microbe 2016 Doitsh G, Greene WC
• Blood-Derived CD4 T Cells Naturally Resist Pyroptosis during Abortive HIV-1 Infection.
  Cell host & microbe 2015 Muñoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC
• Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells.
  Cell reports 2015 Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC
• MicroRNA-155 Reinforces HIV Latency.
  The Journal of biological chemistry 2015 Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC
• Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides.
  Science translational medicine 2014 Zirafi O, Kim KA, Roan NR, Kluge SF, Müller JA, Jiang S, Mayer B, Greene WC, Kirchhoff F, Münch J
• HIV-1 Fusion Assay.
  Bio-protocol 2014 Cavrois M, Neidleman J, Greene WC
• A new activity for SAMHD1 in HIV restriction.
  Nature medicine 2014 Yang Z, Greene WC
• Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection.
  Journal of virology 2014 Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC
• Interaction of fibronectin with semen amyloids synergistically enhances HIV infection.
  The Journal of infectious diseases 2014 Roan NR, Chu S, Liu H, Neidleman J, Witkowska HE, Greene WC
• Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen.
  Nature communications 2014 Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch…
• Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts.
  Human reproduction (Oxford, England) 2014 Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR
• Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.
  Nature 2014 Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC
• An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.
  PLoS pathogens 2013 Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, …
• IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.
  Science (New York, N.Y.) 2013 Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC
• Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains.
  Journal of virology 2013 Cavrois M, Neidleman J, Santiago ML, Derdeyn CA, Hunter E, Greene WC
• Solutions to global health challenges: no more Band-Aids.
  The Journal of clinical investigation 2013 Greene WC
• Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV.
  PloS one 2013 Chan JK, Bhattacharyya D, Lassen KG, Ruelas D, Greene WC
• An integrated overview of HIV-1 latency.
  Cell 2013 Ruelas DS, Greene WC
• Evasion of superinfection exclusion and elimination of primary viral RNA by an adapted strain of hepatitis C virus.
  Journal of virology 2013 Webster B, Ott M, Greene WC
• Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.
  PLoS pathogens 2013 Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M
• Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis.
  Journal of virology 2012 Webster B, Wissing S, Herker E, Ott M, Greene WC
• [Role of semen-derived amyloid fibrils as facilitators of HIV infection].
  Medecine sciences : M/S 2012 Roan NR, Cavrois M, Greene WC
• Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis.
  Immunological reviews 2012 Chan JK, Greene WC
• Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong …
• A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs.
  PloS one 2012 Lassen KG, Hebbeler AM, Bhattacharyya D, Lobritz MA, Greene WC
• Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia.
  Journal of virology 2011 Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM
• Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.
  Cell host & microbe 2011 Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC
• Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection.
  Journal of virology 2011 Arnold F, Schnell J, Zirafi O, Stürzel C, Meier C, Weil T, Ständker L, Forssmann WG, Roan NR, Greene WC, Kirchhoff F, Münch J
• Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility.
  Human molecular genetics 2011 Wissing S, Muñoz-Lopez M, Macia A, Yang Z, Montano M, Collins W, Garcia-Perez JL, Moran JV, Greene WC
• Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.
  PLoS pathogens 2011 Smith DS, Guo K, Barrett BS, Heilman KJ, Evans LH, Hasenkrug KJ, Greene WC, Santiago ML
• HIV latency.
  Cold Spring Harbor perspectives in medicine 2011 Siliciano RF, Greene WC
• Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells.
  The Journal of biological chemistry 2011 Wissing S, Montano M, Garcia-Perez JL, Moran JV, Greene WC
• Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).
  PLoS pathogens 2011 Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M
• NF-κB/Rel: agonist and antagonist roles in HIV-1 latency.
  Current opinion in HIV and AIDS 2011 Chan JK, Greene WC
• Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue.
  Cell 2010 Doitsh G, Cavrois M, Lassen KG, Zepeda O, Yang Z, Santiago ML, Hebbeler AM, Greene WC
• HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells.
  Virology 2010 Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM
• Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.
  Journal of virology 2010 Santiago ML, Smith DS, Barrett BS, Montano M, Benitez RL, Pelanda R, Hasenkrug KJ, Greene WC
• Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif.
  The Journal of biological chemistry 2010 Lassen KG, Wissing S, Lobritz MA, Santiago M, Greene WC
• Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI.
  Retrovirology 2010 Kim KA, Yolamanova M, Zirafi O, Roan NR, Staendker L, Forssmann WG, Burgener A, Dejucq-Rainsford N, Hahn BH, Shaw GM, Greene WC, Kirchhoff F, Münch J
• Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.
  Journal of immunology (Baltimore, Md. : 1950) 2010 Santiago ML, Benitez RL, Montano M, Hasenkrug KJ, Greene WC
• HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors.
  Molecular aspects of medicine 2010 Wissing S, Galloway NL, Greene WC
• Measuring HIV fusion mediated by envelopes from primary viral isolates.
  Methods (San Diego, Calif.) 2010 Cavrois M, Neidleman J, Galloway N, Derdeyn CA, Hunter E, Greene WC
• Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).
  The Journal of biological chemistry 2009 Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC
• APOBEC3G: an intracellular centurion.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2009 Chiu YL, Greene WC
• The challenge of finding a cure for HIV infection.
  Science (New York, N.Y.) 2009 Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ
• Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo.
  Retrovirology 2009 Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT
• Unsung hero Robert C. Gallo.
  Science (New York, N.Y.) 2009 Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny…
• Guidelines for naming nonprimate APOBEC3 genes and proteins.
  Journal of virology 2008 LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, Strebel K, Wain-Hobson S, Yu …
• The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection.
  Journal of virology 2008 Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F, Greene WC
• Novel targets for HIV therapy.
  Antiviral research 2008 Greene WC, Debyser Z, Ikeda Y, Freed EO, Stephens E, Yonemoto W, Buckheit RW, Esté JA, Cihlar T
• Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.
  Science (New York, N.Y.) 2008 Santiago ML, Montano M, Benitez R, Messer RJ, Yonemoto W, Chesebro B, Hasenkrug KJ, Greene WC
• HIV vaccine research: the way forward.
  Science (New York, N.Y.) 2008 Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC
• The achilles heel of the trojan horse model of HIV-1 trans-infection.
  PLoS pathogens 2008 Cavrois M, Neidleman J, Greene WC
• Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation.
  Cell host & microbe 2008 Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M
• The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.
  Annual review of immunology 2008 Chiu YL, Greene WC
• A seminal finding for understanding HIV transmission.
  Cell 2007 Roan NR, Greene WC
• A history of AIDS: looking back to see ahead.
  European journal of immunology 2007 Greene WC
• Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression.
  Retrovirology 2007 Goffinet C, Michel N, Allespach I, Tervo HM, Hermann V, Kräusslich HG, Greene WC, Keppler OT
• Regulation of HIV-1 latency by T-cell activation.
  Cytokine 2007 Williams SA, Greene WC
• The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo.
  Journal of immunology (Baltimore, Md. : 1950) 2007 Ellery PJ, Tippett E, Chiu YL, Paukovics G, Cameron PU, Solomon A, Lewin SR, Gorry PR, Jaworowski A, Greene WC, Sonza S, Crowe SM
• Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1.
  Journal of virology 2007 Williams SA, Kwon H, Chen LF, Greene WC
• APOBEC3G and HIV-1: strike and counterstrike.
  Current HIV/AIDS reports 2007 Soros VB, Greene WC
• Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H.
  PLoS pathogens 2007 Soros VB, Yonemoto W, Greene WC
• In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions.
  PLoS pathogens 2007 Cavrois M, Neidleman J, Kreisberg JF, Greene WC
• Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells.
  The Journal of biological chemistry 2006 Stopak KS, Chiu YL, Kropp J, Grant RM, Greene WC
• A plea for justice for jailed medical workers.
  Science (New York, N.Y.) 2006 Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, …
• High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Chiu YL, Witkowska HE, Hall SC, Santiago M, Soros VB, Esnault C, Heidmann T, Greene WC
• NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity.
  Molecular and cellular biology 2006 O'Mahony A, Raber J, Montano M, Foehr E, Han V, Lu SM, Kwon H, LeFevour A, Chakraborty-Sett S, Greene WC
• Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo.
  Journal of virology 2006 Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V
• APOBEC3G and HIV-1: strike and counterstrike.
  Current infectious disease reports 2006 Soros VB, Greene WC
• Multifaceted antiviral actions of APOBEC3 cytidine deaminases.
  Trends in immunology 2006 Chiu YL, Greene WC
• Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation.
  The Journal of experimental medicine 2006 Kreisberg JF, Yonemoto W, Greene WC
• Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin.
  The Journal of biological chemistry 2006 Chandrasekar B, Mummidi S, Mahimainathan L, Patel DN, Bailey SR, Imam SZ, Greene WC, Valente AJ
• Human immunodeficiency virus fusion to dendritic cells declines as cells mature.
  Journal of virology 2006 Cavrois M, Neidleman J, Kreisberg JF, Fenard D, Callebaut C, Greene WC
• APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle.
  The Journal of biological chemistry 2005 Chiu YL, Greene WC
• NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation.
  The EMBO journal 2005 Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC
• Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement.
  Journal of immunology (Baltimore, Md. : 1950) 2005 Fenard D, Yonemoto W, de Noronha C, Cavrois M, Williams SA, Greene WC
• NF-kappaB RelA phosphorylation regulates RelA acetylation.
  Molecular and cellular biology 2005 Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC
• Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax.
  The Journal of biological chemistry 2005 Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW, Greene WC
• Assessing acetylation of NF-kappaB.
  Methods (San Diego, Calif.) 2005 Chen LF, Greene WC
• Host factors regulating post-integration latency of HIV.
  Trends in microbiology 2005 Williams SA, Greene WC
• Protecting APOBEC3G: a potential new target for HIV drug discovery.
  Current opinion in investigational drugs (London, England : 2000) 2005 Stopak K, Greene WC
• Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef.
  Journal of virology 2005 Keppler OT, Allespach I, Schüller L, Fenard D, Greene WC, Fackler OT
• Studies of ebola virus glycoprotein-mediated entry and fusion by using pseudotyped human immunodeficiency virus type 1 virions: involvement of cytoskeletal proteins and enhancement by tumor necrosis factor alpha.
  Journal of virology 2005 Yonezawa A, Cavrois M, Greene WC
• HIV-1 virion fusion assay: uncoating not required and no effect of Nef on fusion.
  Virology 2004 Cavrois M, Neidleman J, Yonemoto W, Fenard D, Greene WC
• The brightening future of HIV therapeutics.
  Nature immunology 2004 Greene WC
• Redistricting the retroviral restriction factors.
  Nature medicine 2004 Greene WC
• Prostratin antagonizes HIV latency by activating NF-kappaB.
  The Journal of biological chemistry 2004 Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC
• Shaping the nuclear action of NF-kappaB.
  Nature reviews. Molecular cell biology 2004 Chen LF, Greene WC
• p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1.
  The Journal of biological chemistry 2004 Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC
• Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65.
  The Journal of biological chemistry 2004 O'Mahony AM, Montano M, Van Beneden K, Chen LF, Greene WC
• Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes.
  Journal of virology 2004 Schaeffer E, Soros VB, Greene WC
• Fluorescence resonance energy transfer-based HIV-1 virion fusion assay.
  Methods in molecular biology (Clifton, N.J.) 2004 Cavrois M, Neidleman J, Bigos M, Greene WC
• How resting T cells deMURR HIV infection.
  Nature immunology 2004 Greene WC
• Regulation of NF-kappaB action by reversible acetylation.
  Novartis Foundation symposium 2004 Greene WC, Chen LF
• HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.
  Molecular cell 2003 Stopak K, de Noronha C, Yonemoto W, Greene WC
• Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation.
  Journal of molecular medicine (Berlin, Germany) 2003 Chen LF, Greene WC
• Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression.
  The Journal of biological chemistry 2003 Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U
• Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages.
  Journal of virology 2003 Sherman MP, de Noronha CM, Eckstein LA, Hataye J, Mundt P, Williams SA, Neidleman JA, Goldsmith MA, Greene WC
• Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis.
  Journal of virology 2003 Stoddart CA, Geleziunas R, Ferrell S, Linquist-Stepps V, Moreno ME, Bare C, Xu W, Yonemoto W, Bresnahan PA, McCune JM, Greene WC
• Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.
  Nature medicine 2002 Greene WC, Peterlin BM
• HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells.
  The Journal of experimental medicine 2001 Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA
• Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr.
  Science (New York, N.Y.) 2001 de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC
• Duration of nuclear NF-kappaB action regulated by reversible acetylation.
  Science (New York, N.Y.) 2001 Fischle W, Verdin E, Greene WC
• HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.
  Nature 2001 Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC
• Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions.
  Journal of virology 2001 Schaeffer E, Geleziunas R, Greene WC
• Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr.
  Journal of virology 2001 Sherman MP, de Noronha CM, Heusch MI, Greene S, Greene WC
• The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis.
  The Journal of biological chemistry 2000 Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC
• NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2000 Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC
• Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest.
  The Journal of biological chemistry 2000 Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha CM, Greene WC, Wray V, Schubert U
• Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production.
  The EMBO journal 2000 Lin L, DeMartino GN, Greene WC
• Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest.
  Journal of virology 2000 Sherman MP, de Noronha CM, Pearce D, Greene WC
• Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta.
  Molecular and cellular biology 2000 Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC
• Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions.
  Molecular and cellular biology 2000 O'Mahony A, Lin X, Geleziunas R, Greene WC
• The generation of nfkb2 p52: mechanism and efficiency.
  Oncogene 1999 Heusch M, Lin L, Geleziunas R, Greene WC
• Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4.
  Journal of immunology (Baltimore, Md. : 1950) 1999 Bresnahan PA, Yonemoto W, Greene WC
• The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases.
  Immunity 1999 Lin X, Cunningham ET, Mu Y, Geleziunas R, Greene WC
• Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways.
  The Journal of cell biology 1998 Jenkins Y, McEntee M, Weis K, Greene WC
• A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
  Current biology : CB 1998 Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC
• Molecular determinants of NF-kappaB-inducing kinase action.
  Molecular and cellular biology 1998 Lin X, Mu Y, Cunningham ET, Marcu KB, Geleziunas R, Greene WC
• Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors.
  The Journal of infectious diseases 1998 Liegler TJ, Yonemoto W, Elbeik T, Vittinghoff E, Buchbinder SP, Greene WC
• Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases.
  Molecular and cellular biology 1998 Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC
• Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome.
  Cell 1998 Lin L, DeMartino GN, Greene WC
• Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation.
  Current biology : CB 1997 Liu KD, Gaffen SL, Goldsmith MA, Greene WC
• The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro.
  The Journal of biological chemistry 1997 Ghoda L, Lin X, Greene WC
• Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity.
  Virology 1997 Miller MD, Warmerdam MT, Ferrell SS, Benitez R, Greene WC
• HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Powell DM, Amaral MC, Wu JY, Maniatis T, Greene WC
• Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat.
  Journal of virology 1996 Tie F, Adya N, Greene WC, Giam CZ
• Unraveling the function of HIV type 1 Nef.
  AIDS research and human retroviruses 1996 Geleziunas R, Miller MD, Greene WC
• c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.
  The Journal of experimental medicine 1996 Shapiro VS, Mollenauer MN, Greene WC, Weiss A
• Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity.
  The Journal of biological chemistry 1996 Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA
• Inhibition of HIV replication by sense and antisense rev response elements in HIV-based retroviral vectors.
  Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996 Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR
• The alpha chain of the IL-2 receptor determines the species specificity of high-affinity IL-2 binding.
  Cytokine 1996 Liu KD, Greene WC, Goldsmith MA
• Denying HIV safe haven.
  The New England journal of medicine 1996 Greene WC
• Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3.
  The American journal of pathology 1996 Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT
• Is the Nef protein of HIV-1 required for pathogenesis?
  Trends in microbiology 1996 Miller MD, Greene WC
• Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation.
  Molecular and cellular biology 1996 Sun S, Elwood J, Greene WC
• The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes.
  Proceedings of the National Academy of Sciences of the United States of America 1996 Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA
• Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction.
  Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996 Béraud C, Greene WC
• Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association.
  The Journal of biological chemistry 1995 Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC
• Predicting progression to AIDS.
  Annals of internal medicine 1995 Greene WC
• Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction.
  The Journal of biological chemistry 1995 Liu KD, Lai SY, Goldsmith MA, Greene WC
• Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.
  The Journal of biological chemistry 1995 Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC
• Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity.
  Proceedings of the National Academy of Sciences of the United States of America 1995 Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC
• Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.
  Journal of virology 1995 Goldsmith MA, Warmerdam MT, Atchison RE, Miller MD, Greene WC
• Ligand binding by the IL-2 receptor is modulated by intracellular determinants of the IL-2 receptor beta-chain.
  Journal of immunology (Baltimore, Md. : 1950) 1995 Goldsmith MA, Amaral MC, Greene WC
• Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.
  Journal of virology 1995 Miller MD, Warmerdam MT, Page KA, Feinberg MB, Greene WC
• Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene.
  Molecular and cellular biology 1994 Sun SC, Elwood J, Béraud C, Greene WC
• The HIV-1 nef gene acts as a positive viral infectivity factor.
  Trends in microbiology 1994 Miller MD, Feinberg MB, Greene WC
• The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements.
  The Journal of biological chemistry 1994 Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC
• The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation.
  Leukemia 1994 Williamson P, Merida I, Greene WC, Gaulton G
• Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Sun SC, Ganchi PA, Béraud C, Ballard DW, Greene WC
• Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency.
  Molecular and cellular biology 1994 Béraud C, Sun SC, Ganchi P, Ballard DW, Greene WC
• The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages.
  The Journal of experimental medicine 1994 Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB
• A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization.
  Molecular and cellular biology 1993 Ganchi PA, Sun SC, Greene WC, Ballard DW
• Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.
  The EMBO journal 1993 Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P
• AIDS and the immune system.
  Scientific American 1993 Greene WC
• Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo.
  Journal of virology 1993 Bogerd H, Greene WC
• Unexpected effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a mutant IL-2 analog.
  Journal of immunology (Baltimore, Md. : 1950) 1993 Kuziel WA, Ju G, Grdina TA, Greene WC
• NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway.
  Science (New York, N.Y.) 1993 Sun SC, Ganchi PA, Ballard DW, Greene WC
• The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation.
  The Journal of biological chemistry 1993 Merida I, Williamson P, Kuziel WA, Greene WC, Gaulton GN
• Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function.
  Virology 1993 Hammes SR, Greene WC
• The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus.
  Proceedings of the National Academy of Sciences of the United States of America 1993 Doerre S, Sista P, Sun SC, Ballard DW, Greene WC
• I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.
  Molecular biology of the cell 1992 Ganchi PA, Sun SC, Greene WC, Ballard DW
• Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells.
  International immunology 1992 Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC
• Molecular insights into human immunodeficiency virus type 1 pathogenesis.
  Current opinion in immunology 1992 Feinberg MB, Greene WC
• The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation.
  Journal of virology 1992 Walker WH, Stein B, Ganchi PA, Hoffman JA, Kaufman PA, Ballard DW, Hannink M, Greene WC
• Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance.
  Journal of virology 1992 Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassmann R, Greene WC, Hauber J, Böhnlein E
• IL-2-induced signal transduction involves the activation of nuclear NF-kappa B expression.
  Journal of immunology (Baltimore, Md. : 1950) 1992 Arima N, Kuziel WA, Grdina TA, Greene WC
• Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells.
  The Journal of clinical investigation 1992 Kaufman PA, Weinberg JB, Greene WC
• Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein.
  Virology 1992 Smith MR, Greene WC
• The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression.
  Proceedings of the National Academy of Sciences of the United States of America 1992 Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC
• Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation.
  Journal of virology 1991 Arima N, Molitor JA, Smith MR, Kim JH, Daitoku Y, Greene WC
• Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation.
  The New biologist 1991 Molitor JA, Ballard DW, Greene WC
• Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway.
  The Journal of clinical investigation 1991 Smith MR, Greene WC
• The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements.
  Proceedings of the National Academy of Sciences of the United States of America 1991 Bogerd HP, Huckaby GL, Ahmed YF, Hanly SM, Greene WC
• A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene.
  Oncogene 1991 Lee JH, Li YC, Doerre S, Sista P, Ballard DW, Greene WC, Franza BR
• Kappa B binding proteins are constitutively expressed in an IL-2 autocrine human T cell line.
  Journal of immunology (Baltimore, Md. : 1950) 1991 Hémar A, Cereghini S, Cornet V, Blank V, Israël A, Greene WC, Dautry-Varsat A
• Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia.
  The Journal of clinical investigation 1991 Smith MR, Greene WC
• The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation.
  Cell 1991 Ahmed YF, Gilmartin GM, Hanly SM, Nevins JR, Greene WC
• The molecular biology of human immunodeficiency virus type 1 infection.
  The New England journal of medicine 1991 Greene WC
• Functional analyses of the type I human T-cell leukemia virus tax gene product.
  Transactions of the Association of American Physicians 1991 Smith MR, Greene WC
• Rex transregulation of human T-cell leukemia virus type II gene expression.
  Journal of virology 1991 Kim JH, Kaufman PA, Hanly SM, Rimsky LT, Greene WC
• NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells.
  Proceedings of the National Academy of Sciences of the United States of America 1990 Molitor JA, Walker WH, Doerre S, Ballard DW, Greene WC
• The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function.
  Cell 1990 Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Dixon EP, Peffer NJ, Hannink M, Greene WC
• Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes.
  Genes & development 1990 Smith MR, Greene WC
• Functions of the auxiliary gene products of the human immunodeficiency virus type 1.
  Virology 1990 Cullen BR, Greene WC
• The molecular basis for the generation of the human soluble interleukin 2 receptor.
  Cytokine 1990 Rubin LA, Galli F, Greene WC, Nelson DL, Jay G
• Interleukin-2 and the IL-2 receptor: new insights into structure and function.
  The Journal of investigative dermatology 1990 Kuziel WA, Greene WC
• Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.
  Genes & development 1990 Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC
• The human interleukin-2 receptor: insights into subunit structure and growth signal transduction.
  Seminars in immunology 1990 Fung MR, Greene WC
• Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated.
  The Journal of biological chemistry 1990 Mills GB, May C, McGill M, Fung M, Baker M, Sutherland R, Greene WC
• Regulation of HIV-1 gene expression.
  Annual review of immunology 1990 Greene WC
• A second sequence element located 3' to the NF-kappa B-binding site regulates IL-2 receptor-alpha gene induction.
  Journal of immunology (Baltimore, Md. : 1950) 1989 Pomerantz JL, Mauxion F, Yoshida M, Greene WC, Sen R
• Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor.
  Proceedings of the National Academy of Sciences of the United States of America 1989 Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC
• The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeat.
  Proceedings of the National Academy of Sciences of the United States of America 1989 Smith MR, Greene WC
• Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator.
  Nature 1989 Rimsky L, Dodon MD, Dixon EP, Greene WC
• Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer.
  The New biologist 1989 Ballard DW, Böhnlein E, Hoffman JA, Bogerd HP, Dixon EP, Franza BR, Greene WC
• Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.
  Genes & development 1989 Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC
• Regulatory pathways governing HIV-1 replication.
  Cell 1989 Cullen BR, Greene WC
• HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises.
  Immunology today 1989 Greene WC, Böhnlein E, Ballard DW
• Induction of interleukin-2 receptor-alpha gene expression is regulated by post-translational activation of kappa B specific DNA binding proteins.
  The Journal of biological chemistry 1989 Böhnlein E, Ballard DW, Bogerd H, Peffer NJ, Lowenthal JW, Greene WC
• Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins.
  Journal of immunology (Baltimore, Md. : 1950) 1989 Lowenthal JW, Ballard DW, Bogerd H, Böhnlein E, Greene WC
• Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression.
  Science (New York, N.Y.) 1989 Hoyos B, Ballard DW, Böhnlein E, Siekevitz M, Greene WC
• Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins.
  Journal of virology 1989 Böhnlein E, Siekevitz M, Ballard DW, Lowenthal JW, Rimsky L, Bogérd H, Hoffman J, Wano Y, Franza BR, Greene WC
• Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes.
  Proceedings of the National Academy of Sciences of the United States of America 1989 Lowenthal JW, Ballard DW, Böhnlein E, Greene WC
• HIV-1, HTLV-I and the interleukin-2 receptor: insights into transcriptional control.
  Haematology and blood transfusion 1989 Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Ballard DW, Greene WC
• Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth.
  Proceedings of the National Academy of Sciences of the United States of America 1988 Wano Y, Feinberg M, Hosking JB, Bogerd H, Greene WC
• Co-internalization of the p55 and p70 subunits of the high-affinity human interleukin 2 receptor. Evidence for a stable ternary receptor complex.
  The Journal of experimental medicine 1988 Fung MR, Ju G, Greene WC
• Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein.
  Nature 1988 Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC
• Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor.
  Proceedings of the National Academy of Sciences of the United States of America 1988 Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G
• HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene.
  Science (New York, N.Y.) 1988 Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC
• p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei.
  Journal of immunology (Baltimore, Md. : 1950) 1988 Froussard P, Chastagner P, Sommé G, Abadie A, Greene W, Thèze J, Longacre S
• The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV.
  Cell 1988 Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR, Greene WC
• Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation.
  Proceedings of the National Academy of Sciences of the United States of America 1988 Lowenthal JW, Böhnlein E, Ballard DW, Greene WC
• Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor.
  The Journal of biological chemistry 1988 Cullen BR, Podlaski FJ, Peffer NJ, Hosking JB, Greene WC
• Sarcoidosis and interleukin-2 receptors.
  The American review of respiratory disease 1988 Greene WC
• Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation.
  Gastroenterology 1988 Zeitz M, Greene WC, Peffer NJ, James SP
• In: Gallin J, Goldstein I, Snyderman R (Eds.), Inflammation: Basic principles and clinical correlations
  IL-2, IL-2 receptors, and the growth of human T cells 1988 Greene WC
• In: Smith KA (Ed.), Interleukin 2
  New perspectives on the structure of the human high affinity i nterleukin-2 receptor 1988 Wano Y, Dukovich M, Kehrl JH, Greene WC
• New insights into the structure of high-affinity interleukin-2 receptors.
  Recent progress in hormone research 1988 Greene WC, Wano YJ, Dukovich M
• Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells.
  The Journal of clinical investigation 1988 Kehrl JH, Dukovich M, Whalen G, Katz P, Fauci AS, Greene WC
• The human interleukin-2 receptor. Recent studies of structure and regulation.
  Annals of the New York Academy of Sciences 1988 Greene WC, Böhnlein E, Siekevitz M, Franza BR, Lowenthal J
• Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I.
  Science (New York, N.Y.) 1987 Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC
• Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor.
  The Journal of experimental medicine 1987 Lowenthal JW, Greene WC
• Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell.
  Journal of immunology (Baltimore, Md. : 1950) 1987 Rubin LA, Hoekzema GS, Nelson DL, Greene WC, Jay G
• Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein.
  Journal of immunology (Baltimore, Md. : 1950) 1987 Bich-Thuy LT, Dukovich M, Peffer NJ, Fauci AS, Kehrl JH, Greene WC
• Interleukin 1 gene expression in adult T cell leukemia.
  The Journal of clinical investigation 1987 Wano Y, Hattori T, Matsuoka M, Takatsuki K, Chua AO, Gubler U, Greene WC
• The human interleukin-2 receptor: a molecular and biochemical analysis of structure and function.
  Clinical research 1987 Greene WC
• Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.
  Proceedings of the National Academy of Sciences of the United States of America 1987 Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC
• A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors.
  Nature 1987 Dukovich M, Wano Y, Katz P, Cullen BR, Kehrl JH, Greene WC
• Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes.
  Journal of immunology (Baltimore, Md. : 1950) 1987 Holter W, Goldman CK, Casabo L, Nelson DL, Greene WC, Waldmann TA
• High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule.
  Proceedings of the National Academy of Sciences of the United States of America 1987 Bernard O, Fazekas de St Groth B, Ullrich A, Green W, Schlessinger J
• Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.
  Proceedings of the National Academy of Sciences of the United States of America 1987 Robb RJ, Rusk CM, Yodoi J, Greene WC
• Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor.
  The Journal of experimental medicine 1987 Robb RJ, Greene WC
• Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector.
  Molecular biology & medicine 1987 Wano Y, Cullen BR, Svetlik PA, Peffer NJ, Greene WC
• Trans-activator gene of HTLV-II: interpretation.
  Science (New York, N.Y.) 1987 Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA
• An overview of the human interleukin-2 receptor: molecular, biochemical, and functional properties.
  Cancer investigation 1987 Greene WC
• Human interleukin 2 receptor (Tac antigen).
  Methods in enzymology 1987 Greene WC, Leonard WJ
• In: Pruzanki W, Seligmann M (Eds.), Clinical Immunology
  The transactivator (tat) gene of HTLV-II induces the expression of cellular genes involved in T cell growth 1987 Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA
• In: Webb DR, Pierce CW, Cohen S (Eds.), Proceedings of the Fifth International Lymphokine Workshop
  The human high affinity for interleukin-2 receptor 1987 Greene WC, Dukovich M, Wano Y, Kehrl JH, Robb RJ
• Int. J. Immunother. III
  Expression of interleukin-2 receptors in normal and neoplastic T cells 1987 Greene WC
• Proceedings of the AACR 1987
  IL-2, IL-2 receptors and human retroviruses 1987 Greene WC
• Expression of human interleukin-2 receptor cDNA in E. coli.
  Biochemical and biophysical research communications 1986 Chanda PK, Chen GF, Baine Y, Leonard WJ, Greene WC, Chang TW, Chang NT
• Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells.
  Molecular and cellular biology 1986 Neckers LM, Bauer S, McGlennen RC, Trepel JB, Rao K, Greene WC
• Characterization of the human interleukin 2 receptor at the DNA, RNA, and protein level.
  Immunobiology 1986 Greene WC
• The human interleukin-2 receptor: analysis of structure and function.
  Immunological reviews 1986 Greene WC, Depper JM, Krönke M, Leonard WJ
• Selective killing of human T-lymphotropic virus-I infected leukemic T-cells by monoclonal anti-interleukin 2 receptor antibody-ricin A chain conjugates: potentiation by ammonium chloride and monensin.
  Cancer research 1986 Krönke M, Schlick E, Waldmann TA, Vitetta ES, Greene WC
• A secreted form of the human interleukin 2 receptor encoded by an "anchor minus" cDNA.
  Journal of immunology (Baltimore, Md. : 1950) 1986 Treiger BF, Leonard WJ, Svetlik P, Rubin LA, Nelson DL, Greene WC
• Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression.
  Science (New York, N.Y.) 1986 Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA
• Only high-affinity receptors for interleukin 2 mediate internalization of ligand.
  Proceedings of the National Academy of Sciences of the United States of America 1986 Weissman AM, Harford JB, Svetlik PB, Leonard WL, Depper JM, Waldmann TA, Greene WC, Klausner RD
• Growth of human T lymphocytes: an analysis of interleukin 2 and its cellular receptor.
  Progress in hematology 1986 Greene WC, Leonard WJ, Depper JM
• In: Greene WC, moderator. The human interleukin-2 receptor: normal and abnormal expression in T cells and in leukemias induced by the human T lymphotropic retroviruses. Ann. Int. Med
  Deregulated interleukin-2 receptor expression in Adult T-cell Leukemia 1986 Greene WC
• In: Marget M, Lang W, Gabler-Sandberger E (Eds.), Proceedings of the IXth International Congress of Infectious and Parasitic Diseases
  The transactivator (tat) gene of HTLV-II activates IL-2 receptor, IL-2, and class II major histocompatibility complex cellular gene expression 1986 Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA
• In: Pincus S, Pisetsky D, Rosenwasser L (Eds.), Biologically based immunomodulators in the therapy of rheumatic diseases
  The human receptor for interleukin-2: characterization, controversies, and expression in rheumatic diseases 1986 Depper JM, Leonard WJ, Greene WC
• The arrangement of immunoglobulin, T cell antigen receptor, and interleukin 2 receptor genes in human lymphoid neoplasms.
  Symposium on Fundamental Cancer Research 1986 Waldmann TA, Korsmeyer SJ, Greene WC
• The human interleukin-2 receptor.
  Annual review of immunology 1986 Greene WC, Leonard WJ
• The human interleukin-2 receptor: role in normal T-cell growth and association with HTLV-I-induced T-cell leukemia.
  Cold Spring Harbor symposia on quantitative biology 1986 Greene WC, Depper JM, Krönke M, Leonard WJ
• Structure of the human interleukin-2 receptor gene.
  Science (New York, N.Y.) 1985 Leonard WJ, Depper JM, Kanehisa M, Krönke M, Peffer NJ, Svetlik PB, Sullivan M, Greene WC
• Monoclonal antibody OKT11A inhibits and recombinant interleukin 2 (IL 2) augments expression of IL 2 receptors at a pretranslational level.
  Journal of immunology (Baltimore, Md. : 1950) 1985 Reed JC, Greene WC, Hoover RG, Nowell PC
• Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia.
  Cancer research 1985 Waldmann TA, Longo DL, Leonard WJ, Depper JM, Thompson CB, Krönke M, Goldman CK, Sharrow S, Bongiovanni K, Greene WC
• Interleukin 2 receptor gene expression in normal human T lymphocytes.
  Proceedings of the National Academy of Sciences of the United States of America 1985 Leonard WJ, Krönke M, Peffer NJ, Depper JM, Greene WC
• Isolation and expression of complementary DNAs encoding the human interleukin 2 receptor.
  Cancer research 1985 Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA
• Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition.
  The New England journal of medicine 1985 Lane HC, Depper JM, Greene WC, Whalen G, Waldmann TA, Fauci AS
• Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells.
  The Journal of experimental medicine 1985 Greene WC, Robb RJ, Svetlik PB, Rusk CM, Depper JM, Leonard WJ
• Localization of the gene encoding the human interleukin-2 receptor on chromosome 10.
  Science (New York, N.Y.) 1985 Leonard WJ, Donlon TA, Lebo RV, Greene WC
• Deregulation of interleukin-2 receptor gene expression in HTLV-I-induced adult T-cell leukemia.
  Science (New York, N.Y.) 1985 Krönke M, Leonard WJ, Depper JM, Greene WC
• Adult T cell leukemia: a potential target for ricin A chain immunotoxins.
  Blood 1985 Krönke M, Depper JM, Leonard WJ, Vitetta ES, Waldmann TA, Greene WC
• Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
  Proceedings of the National Academy of Sciences of the United States of America 1985 Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC
• Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA.
  Journal of immunology (Baltimore, Md. : 1950) 1985 Miller J, Malek TR, Leonard WJ, Greene WC, Shevach EM, Germain RN
• Sequential expression of genes involved in human T lymphocyte growth and differentiation.
  The Journal of experimental medicine 1985 Krönke M, Leonard WJ, Depper JM, Greene WC
• The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor.
  The Journal of biological chemistry 1985 Leonard WJ, Depper JM, Krönke M, Robb RJ, Waldmann TA, Greene WC
• Activators of protein kinase C and 5-azacytidine induce IL-2 receptor expression on human T lymphocytes.
  Journal of cellular biochemistry 1985 Depper JM, Leonard WJ, Drogula CL, Krönke M, Waldmann TA, Greene WC
• Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation.
  Journal of immunology (Baltimore, Md. : 1950) 1985 Reed JC, Robb RJ, Greene WC, Nowell PC
• In: Cancer Cells 3: Growth factors and transformation
  Structure, function, and expression of the receptor for interleukin-2 on normal and malignant lymphocytes 1985 Waldmann TA, Leonard WJ, Depper JM, Kronke M, Kozak R, Greene WC
• In: Feldman M (Ed.), Human T cell clones: An approach to immune regulation
  Interleukin-2 receptors 1985 Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Bongiovani KF, Greene WC.
• In: Feldmann M, Mitchison NA (Eds.), Immune Regulation
  Molecular cloning and expression of cDNAs encoding the human interleukin-2 receptor 1985 Leonard WJ, Depper JM, Crabtee GM, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC
• In: Pattengale PK, Lukes RJ, Taylor CR (Eds.), Lymphoproliferative Diseases: Pathogenesis, Diagnosis, and Therapy
  Molecular analysis of the human interleukin-2 receptor 1985 Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Leonard WJ
• In: Pinchera A, Doria G, Dammacco F, Bargellesi A (Eds.), Monoclonal Antibodies 1984: Biological and Clinical Applications
  Interleukin-2 receptors on lymphocytes 1985 Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Sharrow S, Greene WC
• In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines
  Cyclosporin A inhibits expression of select T-cell activation genes 1985 Kronke M, Depper JM, Leonard WJ, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC
• In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines
  Cloning of cDNAs for the human interleukin-2 receptor and determination of its complete protein sequence 1985 Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC
• In: Sorg P, Schimple A (Eds.), Cellular and molecular biology of lymphokines
  The role of protein kinase C, and effects of 5-azacytidine on regulation on interleukin-2 receptor expression 1985 Depper JM, Leonard WJ, Kronke M, Waldmann TA, Greene WC
• Molecular cloning of cDNA for the human interleukin-2 receptor.
  Haematology and blood transfusion 1985 Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA
• Receptors for T-cell growth factor: structure, function and expression on normal and neoplastic cells.
  Contemporary topics in molecular immunology 1985 Greene WC, Robb RJ
• The human interleukin-2 receptor.
  Journal of cell science. Supplement 1985 Greene WC, Depper JM, Krönke M, Leonard WJ
• Cellular origin of hairy cell leukemia: malignant B cells that express receptors for T cell growth factor.
  Seminars in oncology 1984 Korsmeyer SJ, Greene WC, Waldmann TA
• Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen.
  Journal of immunology (Baltimore, Md. : 1950) 1984 Depper JM, Leonard WJ, Krönke M, Noguchi PD, Cunningham RE, Waldmann TA, Greene WC
• Expression of interleukin 2 receptors on activated human B cells.
  The Journal of experimental medicine 1984 Waldmann TA, Goldman CK, Robb RJ, Depper JM, Leonard WJ, Sharrow SO, Bongiovanni KF, Korsmeyer SJ, Greene WC
• Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells.
  Journal of immunology (Baltimore, Md. : 1950) 1984 Depper JM, Leonard WJ, Krönke M, Waldmann TA, Greene WC
• Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.
  The Journal of experimental medicine 1984 Robb RJ, Greene WC, Rusk CM
• Molecular cloning and expression of cDNAs for the human interleukin-2 receptor.
  Nature 1984 Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik PB, Peffer NJ, Waldmann TA
• Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription.
  Proceedings of the National Academy of Sciences of the United States of America 1984 Krönke M, Leonard WJ, Depper JM, Arya SK, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC
• Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells.
  Journal of immunology (Baltimore, Md. : 1950) 1984 Greene WC, Robb RJ, Depper JM, Leonard WJ, Drogula C, Svetlik PB, Wong-Staal F, Gallo RC, Waldmann TA
• Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor.
  The Journal of clinical investigation 1984 Waldmann TA, Greene WC, Sarin PS, Saxinger C, Blayney DW, Blattner WA, Goldman CK, Bongiovanni K, Sharrow S, Depper JM
• Expression of receptors for interleukin 2: Role in the commitment of T lymphocytes to proliferate.
  Journal of immunology (Baltimore, Md. : 1950) 1984 Lipkowitz S, Greene WC, Rubin AL, Novogrodsky A, Stenzel KH
• In: Greaves M (Ed.), Receptors and Recognition
  A monoclonal antibody to the human receptor for T cell growth factor 1984 Leonard WJ, Depper JM, Waldmann TA, Greene WC
• In: Pick E (Ed.), Lymphokines
  A monoclonal antibody which recognizes the human receptor for T cell growth factor: Functional effects and use as a probe to investigate receptor regulation 1984 Depper JM, Leonard WJ, Waldmann TA, Greene WC
• In: Sasazuki T (Ed.), Immunogenetics: Its application to clinical medicine
  Cell-cell interactions in the human immune response: Analysis of leukemic T calls with immunoregulatory functions 1984 Waldmann TA, Broder S, Greene WC
• Interleukin-2 receptor expression in retrovirus associated adult T-cell leukemia.
  Princess Takamatsu symposia 1984 Waldmann TA, Leonard WJ, Depper JM, Krönke M, Goldman CK, Oh T, Greene WC
• Interleukin-2 receptors on activated malignant and normal B-cells.
  Current topics in microbiology and immunology 1984 Waldmann TA, Goldman CK, Leonard WJ, Depper JM, Robb RJ, Korsmeyer SJ, Greene WC
• Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques.
  The Journal of clinical investigation 1983 Littman BH, Muchmore AV, Steinberg AD, Greene WC
• Characterization of the human receptor for T-cell growth factor.
  Proceedings of the National Academy of Sciences of the United States of America 1983 Leonard WJ, Depper JM, Robb RJ, Waldmann TA, Greene WC
• Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor.
  Nature 1983 Lando Z, Sarin P, Megson M, Greene WC, Waldman TA, Gallo RC, Broder S
• Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen.
  The Journal of experimental medicine 1983 Robb RJ, Greene WC
• Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation.
  Journal of immunology (Baltimore, Md. : 1950) 1983 Depper JM, Leonard WJ, Robb RJ, Waldmann TA, Greene WC
• Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia.
  Proceedings of the National Academy of Sciences of the United States of America 1983 Korsmeyer SJ, Greene WC, Cossman J, Hsu SM, Jensen JP, Neckers LM, Marshall SL, Bakhshi A, Depper JM, Leonard WJ, Jaffe ES, Waldmann TA
• Evidence for an interleukin-independent pathway for human lymphocyte activation.
  Proceedings of the National Academy of Sciences of the United States of America 1983 Koretzky GA, Daniele RP, Greene WC, Nowell PC
• Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen.
  The Journal of experimental medicine 1983 Cossman J, Neckers LM, Leonard WJ, Greene WC
• Construction of human suppressor T cell hybridomas.
  Lymphokine research 1983 Greene WC, Depper JM, Leonard WJ, Fleisher TA, Waldmann TA
• In: Golde DW, Marks PA (Eds.), Normal and Neoplastic Hematopoiesis, UCLA Symposia on Molecular and Cellular Biology
  Hairy cell leukemia: A malignant expansion of B cells that express Tac antigen 1983 Greene WC, Cossman J, Leonard WJ, Bakshi A, Waldmann TA, Korsmeyer SJ
• The role of cell surface lectin--carbohydrate interactions in cellular recognition, cooperation, and regulation.
  The American journal of pediatric hematology/oncology 1983 Blaese RM, Tosato G, Greene WC, Fleisher TA, Muchmore AV
• A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor.
  Nature 1982 Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC
• Production of human suppressor T cell hybridomas.
  Journal of immunology (Baltimore, Md. : 1950) 1982 Greene WC, Fleisher TA, Nelson DL, Waldmann TA
• Characterization of a soluble suppressor of human B cell function produced by a continuous human suppressor T cell line. II. Evidence for suppression through a direct action of CTC-SISS-B on human B cells.
  Journal of immunology (Baltimore, Md. : 1950) 1982 Greene WC, Fleisher TA, Depper JM, Leonard WJ, Stanton GJ, Waldmann TA
• Interferon-mediated inhibition of human polyclonal immunoglobulin synthesis.
  Journal of immunology (Baltimore, Md. : 1950) 1982 Fleisher TA, Attallah AM, Tosato G, Blaese RM, Greene WC
• In: Oppenheim JJ, Cohen S (Eds.), Interleukins, lymphokines, and cytokines
  Monoclonal anti-Tac blocks the action of human interleukin-2 1982 Depper JM, Leonard WJ, Smith KA, Waldmann TA, Greene WC
• Stimulation of immunoglobulin biosynthesis in human B cells by wheat germ agglutinin. I. Evidence that WGA can produce both a positive and negative signal for activation of human lymphocytes.
  Journal of immunology (Baltimore, Md. : 1950) 1981 Greene WC, Goldman CK, Marshall ST, Fleisher TA, Waldmann TA
• Characterization of a soluble suppressor of human B cell immunoglobulin biosynthesis produced by a continuous human suppressor T cell line.
  The Journal of experimental medicine 1981 Fleisher TA, Greene WC, Uchiyama T, Goldman CK, Nelson DL, Blaese RM, Waldmann TA
• Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. I. Characterization of a soluble suppressor T cell proliferation.
  Journal of immunology (Baltimore, Md. : 1950) 1981 Greene WC, Fleisher TA, Waldmann TA
• Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. II. Characterization of a soluble suppressor of B cell immunoglobulin production.
  Journal of immunology (Baltimore, Md. : 1950) 1981 Fleisher TA, Greene WC, Blaese RM, Waldmann TA
• Suppression of human T and B lymphocyte activation by Agaricus bisporus lectin. I. Suggestive evidence for a surface "suppressor" receptor in human lymphocytes.
  Journal of immunology (Baltimore, Md. : 1950) 1981 Greene WC, Fleisher TA, Waldmann TA
• Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin.
  Journal of immunology (Baltimore, Md. : 1950) 1980 Greene WC, Waldmann TA
• In: Cramer H, Schultz J (Eds.), Mechanism of Action
  Cyclic nucleotides in the immune response 1977 Parker CW, Greene WC
• Cytochalasin binding in lymphocytes and polymorphonuclear leukocytes.
  Experimental cell research 1976 Parker CW, Greene WC, MacDonald HH
• Cytochalasin sensitive structures and lymphocyte activation.
  Experimental cell research 1976 Greene WC, Parker CM, Parker CW
• Colchicine-sensitive structures and lymphocyte activation.
  Journal of immunology (Baltimore, Md. : 1950) 1976 Greene WC, Parker CM, Parker CW
• Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal.
  The Journal of biological chemistry 1976 Greene WC, Parker CM, Parker CW
• Calcium and lymphocyte activation.
  Cellular immunology 1976 Greene WC, Parker CM, Parker CW
• Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers.
  Experimental cell research 1976 Atkinson JP, Greene WC, McNearney TA, Parker CW
• In: Eijsvoogel W, Roos D, Zeijlemaker WP (Eds.), Leukocyte membrane determinants regulating immune reactivity
  Calcium ionophore A23187 and lymphocyte activation 1976 Greene WC, Wedner HJ, Parker CW
• Suggestive evidence for both stimulatory and inhibitory domains on human lymphocytes, as indicated by phospholipid turnover studies with wheat germ agglutinin and other lectins.
  Immunological communications 1976 Parker CW, Dankner RE, Falkenhein SF, Greene WC
• A role for cytochalasin-sensitive proteins in the regulation of calcium transport in activated human lymphocytes.
  Biochemical and biophysical research communications 1975 Greene WC, Parker CW
• Concanavalin A-induced histamine release from normal rat mast cells.
  Journal of immunology (Baltimore, Md. : 1950) 1975 Sullivan TJ, Greene WC, Parker CW
• Effect of experimental diabetes mellitus on kidney ribosomal protein synthesis.
  Diabetes 1971 Peterson DT, Greene WC, Reaven GM