Victor Valcour, MD, PhD
Professor
Neurology
School of Medicine

Dr. Valcour is a Professor of Medicine with a shared appointment in the Division of Geriatric Medicine and the Department of Neurology. His work crosses disciplines to research and care for cognitive disorders in aging populations and to understand brain injury in the setting of HIV among all ages, including funded pediatric HIV studies. His clinical work involves consultations for patients with cognitive disorders at the Memory and Aging Center/UCSF.

While much of Dr. Valcour's research is completed at UCSF, he has a large internationa porfolio with many opportunities for junior investigators. Within Southeast Asia, he is Deputy Director of SEARCH/Thailand operating research in acute HIV (within days of infection), pediatric HIV, and markers of dementia in chronic HIV. In Africa, he has partnered with the US Military HIV Research Program to survey cognitive disorders among HIV-infected individuals in Nigeria, Uganda, Kenya, and Tanzania.

Dr. Valcour is broadly involved in mentoring individuals at all levels of training who are interested in clinical research related to cognitive disorders, particularly in association with HIV infection. He has extensive global health experience.

RESEARCH

Dr. Valcour’s research interests have two major emphases. He is currently developing a research program that aims to understand optimal care strategies for elders who develop dementia. Nested within the UCSF Memory and Aging Center, the long-term goal of this program is to provide model care for elders with cognitive disorders.

Dr. Valcour is internationally recognized for research in cognitive disorders related to HIV. He currently operates 3 NIH R01 series grants within 3 novel cohorts: (1) a chronic HIV infected cohort followed since first initiation of cART; (2) an acute HIV cohort of individuals infected for less than one month at enrollment; (3) and a pediatric cohort in Thailand and Cambodia. He is the Deputy Director of SEARCH/Thailand (www.SEARCHThailand.org). He also operates the UCSF HIV Over 60 Cohort focused on understanding cognitive disorders in the older HIV population living in the San Francisco Bay area. New research will survey of cognitive disorders in HIV for individuals living in Uganda, Kenya, Tanzania and Nigeria.

ACADEMIC FOCUS

Dr. Valcour is actively engaged in mentoring individuals wishing to become independent clinical researchers. His research portfolio provides a broad array of local and international projects that can serve as resources for mentored projects. Dr. Valcour serves as an Executive Committee member of the AIDS Research Institute (ARI)

• Impact of respect, equity, and leadership in brain health.
  Frontiers in neurology 2023 Arshad F, Zegarra-Valdivia JA, Prioleau C, Valcour V, Miller BL
• Visual deep learning of unprocessed neuroimaging characterises dementia subtypes and generalises across non-stereotypic samples.
  EBioMedicine 2023 Moguilner S, Whelan R, Adams H, Valcour V, Tagliazucchi E, Ibáñez A
• The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2023 Maestre G, Carrillo M, Kalaria R, Acosta D, Adams L, Adoukonou T, Akinwande K, Akinyemi J, Akinyemi R, Akpa O, Alladi S, Allegri R, Arizaga R, Arshad F, Arulogun O, Babalola D, Baiyewu O, Bak T, …
• The need for a tailored national dementia plan in Ethiopia: A call for action.
  Frontiers in neurology 2023 Ayele BA, Ali S, Anbessie M, Zewde YZ, Yoseph S, Lee S, Valcour V, Miller B
• Immunological, Cognitive, and Psychiatric Outcomes After Initiating Efavirenz- and Dolutegravir-based Antiretroviral Therapy During Acute Human Immunodeficiency Virus Infection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023 Chan P, Yoon B, Colby D, Kroon E, Sacdalan C, Sriplienchan S, Pinyakorn S, Ananworanich J, Valcour V, Vasan S, Hsu D, Phanuphak N, Paul R, Spudich S
• Brain volumetrics differ by Fiebig stage in acute HIV infection.
  AIDS (London, England) 2023 Bolzenius J, Sacdalan C, Ndhlovu LC, Sailasuta N, Trautmann L, Tipsuk S, Crowell TA, Suttichom D, Colby DJ, Phanuphak N, Chan P, Premeaux T, Kroon E, Vasan S, Hsu DC, Valcour V, Ananworanich J, Robb …
• Neurocognition and the Aging Brain in People With HIV: Implications for Screening.
  Topics in antiviral medicine 2022 Chan P, Valcour V
• Classification of Alzheimer's disease and frontotemporal dementia using routine clinical and cognitive measures across multicentric underrepresented samples: A cross sectional observational study.
  Lancet regional health. Americas 2022 Maito MA, Santamaría-García H, Moguilner S, Possin KL, Godoy ME, Avila-Funes JA, Behrens MI, Brusco IL, Bruno MA, Cardona JF, Custodio N, García AM, Javandel S, Lopera F, Matallana DL, Miller B, de …
• Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
  EBioMedicine 2022 Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey…
• Individual Differences in CD4/CD8 T-Cell Ratio Trajectories and Associated Risk Profiles Modeled From Acute HIV Infection.
  Psychosomatic medicine 2022 Paul R, Cho K, Bolzenius J, Sacdalan C, Ndhlovu LC, Trautmann L, Krebs S, Tipsuk S, Crowell TA, Suttichom D, Colby DJ, Premeaux TA, Phanuphak N, Chan P, Kroon E, Vasan S, Hsu D, Carrico A, Valcour V, …
• The Latin American Brain Health Institute, a regional initiative to reduce the scale and impact of dementia.
  Alzheimer's & dementia : the journal of the Alzheimer's Association 2022 Duran-Aniotz C, Sanhueza J, Grinberg LT, Slachevsky A, Valcour V, Robertson I, Lawlor B, Miller B, Ibáñez A
• Cognitive dysfunction following COVID-19 infection.
  Journal of neurovirology 2022 Hadad R, Khoury J, Stanger C, Fisher T, Schneer S, Ben-Hayun R, Possin K, Valcour V, Aharon-Peretz J, Adir Y
• Facilitators and Barriers to Dementia Assessment and Diagnosis: Perspectives From Dementia Experts Within a Global Health Context.
  Frontiers in neurology 2022 Bernstein Sideman A, Al-Rousan T, Tsoy E, Piña Escudero SD, Pintado-Caipa M, Kanjanapong S, Mbakile-Mahlanza L, Okada de Oliveira M, De la Cruz-Puebla M, Zygouris S, Ashour Mohamed A, Ibrahim H, Goode…
• Race, Genetic Admixture, and Cognitive Performance in the Cuban Population.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2022 Llibre-Guerra JJ, Li Y, Allen IE, Llibre-Guerra JC, Rodríguez Salgado AM, Peñalver AI, Almirall Sanchez A, Yokoyama JS, Grinberg L, Valcour V, Miller BL, Llibre-Rodríguez JJ
• Validity of Digital Assessments in Screening for HIV-Related Cognitive Impairment: a Review.
  Current HIV/AIDS reports 2021 Wilson S, Milanini B, Javandel S, Nyamayaro P, Valcour V
• Multi-label, multi-domain learning identifies compounding effects of HIV and cognitive impairment.
  Medical image analysis 2021 Zhang J, Zhao Q, Adeli E, Pfefferbaum A, Sullivan EV, Paul R, Valcour V, Pohl KM
• Central Nervous System Safety During Brief Analytic Treatment Interruption of Antiretroviral Therapy Within 4 Human Immunodeficiency Virus Remission Trials: An Observational Study in Acutely Treated People Living With Human Immunodeficiency Virus.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2021 Hellmuth J, Muccini C, Colby DJ, Kroon E, de Souza M, Crowell TA, Chan P, Sacdalan C, Intasan J, Benjapornpong K, Tipsuk S, Puttamaswin S, Chomchey N, Valcour V, Sarnecki M, Tomaka F, Krebs SJ, Slike …
• Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART.
  PLoS pathogens 2021 Corley MJ, Sacdalan C, Pang APS, Chomchey N, Ratnaratorn N, Valcour V, Kroon E, Cho KS, Belden AC, Colby D, Robb M, Hsu D, Spudich S, Paul R, Vasan S, Ndhlovu LC, SEARCH010/RV254 and SEARCH013/RV304 …
• Cerebrovascular Disease Correlates With Longitudinal Brain Atrophy in Virally Suppressed Older People Living With HIV.
  Journal of acquired immune deficiency syndromes (1999) 2021 Samboju V, Cobigo Y, Paul R, Naasan G, Hillis M, Tsuei T, Javandel S, Valcour V, Milanini B
• Ensemble machine learning classification of daily living abilities among older people with HIV.
  EClinicalMedicine 2021 Paul R, Tsuei T, Cho K, Belden A, Milanini B, Bolzenius J, Javandel S, McBride J, Cysique L, Lesinski S, Valcour V
• Cognitive trajectories after treatment in acute HIV infection.
  AIDS (London, England) 2021 Chan P, Kerr SJ, Kroon E, Colby D, Sacdalan C, Hellmuth J, Reiss P, Vasan S, Ananworanich J, Valcour V, Spudich S, Paul R, RV254/SEARCH 010 Research Team
• Minimal detection of cerebrospinal fluid escape after initiation of antiretroviral therapy in acute HIV-1 infection.
  AIDS (London, England) 2021 Handoko R, Chan P, Jagodzinski L, Pinyakorn S, Ubolyam S, Phanuphak N, Sacdalan C, Kroon E, Dumrongpisutikul N, Paul R, Valcour V, Ananworanich J, Vasan S, Spudich S, SEARCH010/RV254 Study Team
• Clinical and laboratory impact of concomitant syphilis infection during acute HIV.
  HIV medicine 2021 Chan P, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Paul R, Robb M, Valcour V, Ananworanich J, Marra C, Spudich S
• The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science.
  Frontiers in neurology 2021 Ibanez A, Yokoyama JS, Possin KL, Matallana D, Lopera F, Nitrini R, Takada LT, Custodio N, Sosa Ortiz AL, Avila-Funes JA, Behrens MI, Slachevsky A, Myers RM, Cochran JN, Brusco LI, Bruno MA, Brucki …
• Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV.
  JAMA network open 2021 Nir TM, Fouche JP, Ananworanich J, Ances BM, Boban J, Brew BJ, Chaganti JR, Chang L, Ching CRK, Cysique LA, Ernst T, Faskowitz J, Gupta V, Harezlak J, Heaps-Woodruff JM, Hinkin CH, Hoare J, Joska JA, …
• A Brief Digital Cognitive Assessment for Detection of Cognitive Impairment in Cuban Older Adults.
  Journal of Alzheimer's disease : JAD 2021 Rodríguez-Salgado AM, Llibre-Guerra JJ, Tsoy E, Peñalver-Guia AI, Bringas G, Erlhoff SJ, Kramer JH, Allen IE, Valcour V, Miller BL, Llibre-Rodríguez JJ, Possin KL
• Global Perspectives on Brief Cognitive Assessments for Dementia Diagnosis.
  Journal of Alzheimer's disease : JAD 2021 Tsoy E, Sideman AB, Piña Escudero SD, Pintado-Caipa M, Kanjanapong S, Al-Rousan T, Mbakile-Mahlanza L, de Oliveira MO, De la Cruz Puebla M, Zygouris S, Mohamed AA, Ibrahim H, Goode CA, Miller BL, …
• Impact of age on CD4 recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study.
  AIDS research and therapy 2020 Bahemana E, Esber A, Dear N, Ganesan K, Parikh A, Reed D, Maganga L, Khamadi S, Mizinduko M, Lwilla A, Mkondoo D, Mwaisanga G, Somi N, Owouth J, Maswai J, Kiweewa F, Iroezindu M, Ake JA, Crowell TA, …
• Factors Predicting Detrimental Change in Declarative Memory Among Women With HIV: A Study of Heterogeneity in Cognition.
  Frontiers in psychology 2020 Fitzgerald KC, Maki PM, Xu Y, Jin W, Dastgheyb R, Williams DW, Springer G, Anastos K, Gustafson D, Spence AB, Adimora AA, Waldrop D, Vance DE, Bolivar H, Valcour VG, Rubin LH
• Mindfulness-based stress reduction for HIV-associated neurocognitive disorder: Rationale and protocol for a randomized controlled trial in older adults.
  Contemporary clinical trials 2020 Addington EL, Javandel S, De Gruttola V, Paul R, Milanini B, Ances BM, Moskowitz JT, Valcour V
• Determinants of suboptimal CD4+ T cell recovery after antiretroviral therapy initiation in a prospective cohort of acute HIV-1 infection.
  Journal of the International AIDS Society 2020 Handoko R, Colby DJ, Kroon E, Sacdalan C, de Souza M, Pinyakorn S, Prueksakaew P, Munkong C, Ubolyam S, Akapirat S, Chiarella J, Krebs S, Sereti I, Valcour V, Paul R, Michael NL, Phanuphak N, …
• HIV and risk of dementia in older veterans.
  AIDS (London, England) 2020 Bobrow K, Xia F, Hoang T, Valcour V, Yaffe K
• Monocyte and CD4+ T-cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment.
  AIDS (London, England) 2020 Sharma V, Bryant C, Montero M, Creegan M, Slike B, Krebs SJ, Ratto-Kim S, Valcour V, Sithinamsuwan P, Chalermchai T, Eller MA, Bolton DL, SEARCH007/SEARCH011 Study Groups
• Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy.
  Frontiers in immunology 2020 Premeaux TA, Javandel S, Hosaka KRJ, Greene M, Therrien N, Allen IE, Corley MJ, Valcour VG, Ndhlovu LC
• Brief Report: Higher Peripheral Monocyte Activation Markers Are Associated With Smaller Frontal and Temporal Cortical Volumes in Women With HIV.
  Journal of acquired immune deficiency syndromes (1999) 2020 Kamkwalala AR, Wang X, Maki PM, Williams DW, Valcour VG, Damron A, Tien PC, Weber KM, Cohen MH, Sundermann EE, Meyer VJ, Little DM, Xu Y, Rubin LH
• Phyloanatomic characterization of the distinct T cell and monocyte contributions to the peripheral blood HIV population within the host.
  Virus evolution 2020 RifeMagalis B, Strickland SL, Shank SD, Autissier P, Schuetz A, Sithinamsuwan P, Lerdlum S, Fletcher JLK, de Souza M, Ananworanich J, Valcour V, Search007 Study Group, Williams KC, Kosakovsky Pond SL,…
• Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV.
  Frontiers in integrative neuroscience 2020 Rubin LH, Xu Y, Norris PJ, Wang X, Dastgheyb R, Fitzgerald KC, Keating SM, Kaplan RC, Maki PM, Anastos K, Springer G, Benning L, Kassaye S, Gustafson DR, Valcour VG, Williams DW
• Machine-learning classification of neurocognitive performance in children with perinatal HIV initiating de novo antiretroviral therapy.
  AIDS (London, England) 2020 Paul RH, Cho KS, Belden AC, Mellins CA, Malee KM, Robbins RN, Salminen LE, Kerr SJ, Adhikari B, Garcia-Egan PM, Sophonphan J, Aurpibul L, Thongpibul K, Kosalaraksa P, Kanjanavanit S, Ngampiyaskul C, …
• Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection.
  Science translational medicine 2020 Leyre L, Kroon E, Vandergeeten C, Sacdalan C, Colby DJ, Buranapraditkun S, Schuetz A, Chomchey N, de Souza M, Bakeman W, Fromentin R, Pinyakorn S, Akapirat S, Trichavaroj R, Chottanapund S, …
• Regional brain volumetric changes despite 2 years of treatment initiated during acute HIV infection.
  AIDS (London, England) 2020 Kallianpur KJ, Jahanshad N, Sailasuta N, Benjapornpong K, Chan P, Pothisri M, Dumrongpisutikul N, Laws E, Ndhlovu LC, Clifford KM, Paul R, Jagodzinski L, Krebs S, Ananworanich J, Spudich S, Valcour V,…
• Frequency and Predictors of HIV-Related Cognitive Impairment in East Africa: The Africa Cohort Study (AFRICOS).
  Journal of acquired immune deficiency syndromes (1999) 2020 Milanini B, Allen I, Paul R, Bahemana E, Kiweewa F, Nambuya A, Maswai J, Langat R, Owuoth J, Martin S, Possin K, Esber A, Polyak C, Ake JA, Valcour V, AFRICOS study Team
• Plasma inflammatory biomarkers link to diffusion tensor imaging metrics in virally suppressed HIV-infected individuals.
  AIDS (London, England) 2020 Chang K, Premeaux TA, Cobigo Y, Milanini B, Hellmuth J, Rubin LH, Javandel S, Allen I, Ndhlovu LC, Paul R, Valcour V
• Resting-state neural signatures of depressive symptoms in acute HIV.
  Journal of neurovirology 2020 Philippi CL, Reyna L, Nedderman L, Chan P, Samboju V, Chang K, Phanuphak N, Ratnaratorn N, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Robb ML, Ananworanich J, Spudich S, Valcour V, …
• Neuropsychiatric outcomes before and after switching to dolutegravir-based therapy in an acute HIV cohort.
  AIDS research and therapy 2020 Chan P, Goh O, Kroon E, Colby D, Sacdalan C, Pinyakorn S, Prueksakaew P, Reiss P, Ananworanich J, Valcour V, Spudich S, Paul R, RV254/SEARCH 010 Research Team
• Psychosocial Resources and Emotions in Women Living With HIV Who Have Cognitive Impairment: Applying the Socio-Emotional Adaptation Theory.
  Research and theory for nursing practice 2020 Halpin SN, Ge L, Mehta CC, Gustafson D, Robertson KR, Rubin LH, Sharma A, Vance D, Valcour V, Waldrop-Valverde D, Ofotokun I
• Infrequent HIV Infection of Circulating Monocytes during Antiretroviral Therapy.
  Journal of virology 2019 Massanella M, Bakeman W, Sithinamsuwan P, Fletcher JLK, Chomchey N, Tipsuk S, Chalermchai T, Routy JP, Ananworanich J, Valcour VG, Chomont N
• Very Early Initiation of Antiretroviral Therapy During Acute HIV Infection Is Associated With Normalized Levels of Immune Activation Markers in Cerebrospinal Fluid but Not in Plasma.
  The Journal of infectious diseases 2019 Hellmuth J, Slike BM, Sacdalan C, Best J, Kroon E, Phanuphak N, Fletcher JLK, Prueksakaew P, Jagodzinski LL, Valcour V, Robb M, Ananworanich J, Allen IE, Krebs SJ, Spudich S
• Neurosyphilis During Acute HIV Infection: A CNS Immunologic and Virologic Characterization.
  Journal of acquired immune deficiency syndromes (1999) 2019 Chan P, Dumrongpisutikul N, Subra C, Colby DJ, Kroon E, Fletcher J, Sacdalan C, Phanuphak N, Valcour V, Ananworanich J, Trautmann L, Spudich S
• Monocyte activation, HIV, and cognitive performance in East Africa.
  Journal of neurovirology 2019 Muñoz-Nevárez LA, Imp BM, Eller MA, Kiweewa F, Maswai J, Polyak C, Olwenyi OA, Allen IE, Rono E, Milanini B, Kibuuka H, Ake JA, Eller LA, Valcour VG
• Deep Sequencing Reveals Central Nervous System Compartmentalization in Multiple Transmitted/Founder Virus Acute HIV-1 Infection.
  Cells 2019 Tovanabutra S, Sirijatuphat R, Pham PT, Bonar L, Harbolick EA, Bose M, Song H, Chang D, Oropeza C, O'Sullivan AM, Balinang J, Kroon E, Colby DJ, Sacdalan C, Hellmuth J, Chan P, Prueksakaew P, …
• Noninfectious Comorbidity in the African Cohort Study.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Ake JA, Polyak CS, Crowell TA, Kiweewa F, Semwogerere M, Maganga L, Bahemana E, Maswai J, Langat R, Owuoth J, Otieno S, Keshinro B, Esber AL, Liu M, Eller LA, Ganesan K, Parikh AP, Hamm TE, Robb ML, …
• Longitudinal brain atrophy patterns and neuropsychological performance in older adults with HIV-associated neurocognitive disorder compared with early Alzheimer's disease.
  Neurobiology of aging 2019 Milanini B, Samboju V, Cobigo Y, Paul R, Javandel S, Hellmuth J, Allen I, Miller B, Valcour V
• Elevated Depressive Symptoms Are a Stronger Predictor of Executive Dysfunction in HIV-Infected Women Than in Men.
  Journal of acquired immune deficiency syndromes (1999) 2019 Rubin LH, Springer G, Martin EM, Seaberg EC, Sacktor NC, Levine A, Valcour VG, Young MA, Becker JT, Maki PM
• Geriatric Syndromes in Older Adults Living with HIV and Cognitive Impairment.
  Journal of the American Geriatrics Society 2019 Hosaka KRJ, Greene M, Premeaux TA, Javandel S, Allen IE, Ndhlovu LC, Valcour V
• Emotional and behavioral resilience among children with perinatally acquired HIV in Thailand and Cambodia.
  AIDS (London, England) 2019 Malee KM, Kerr S, Paul R, Puthanakit T, Thongpibul K, Kosalaraksa P, Ounchanum P, Kanjanavanit S, Aurpibul L, Ngampiyaskul C, Luesomboon W, Wongsawat J, Vonthanak S, Ly PS, Chettra K, Suwanlerk T, …
• East African HIV care: depression and HIV outcomes.
  Global mental health (Cambridge, England) 2019 Meffert SM, Neylan TC, McCulloch CE, Maganga L, Adamu Y, Kiweewa F, Maswai J, Owuoth J, Polyak CS, Ake JA, Valcour VG
• Mapping abnormal subcortical neurodevelopment in a cohort of Thai children with HIV.
  NeuroImage. Clinical 2019 Wade BSC, Valcour VG, Puthanakit T, Saremi A, Gutman BA, Nir TM, Watson C, Aurpibul L, Kosalaraksa P, Ounchanum P, Kerr S, Dumrongpisutikul N, Visrutaratna P, Srinakarin J, Pothisri M, Narr KL, …
• Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals.
  Journal of neurovirology 2018 Premeaux TA, D'Antoni ML, Abdel-Mohsen M, Pillai SK, Kallianpur KJ, Nakamoto BK, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Gisslén M, Price RW, Valcour V, Ndhlovu LC
• Abnormal Cerebral Perfusion Profile in Older Adults with HIV-Associated Neurocognitive Disorder: Discriminative Power of Arterial Spin-Labeling.
  AJNR. American journal of neuroradiology 2018 Narvid J, McCoy D, Dupont SM, Callen A, Tosun D, Hellmuth J, Valcour V
• Limitations of the International HIV Dementia Scale in the current era.
  AIDS (London, England) 2018 Milanini B, Paul R, Bahemana E, Adamu Y, Kiweewa F, Langat R, Owuoth J, Allen E, Polyak C, Ake J, Valcour V, AFRICOS study Team
• Mixed TDP-43 proteinopathy and tauopathy in frontotemporal lobar degeneration: nine case series.
  Journal of neurology 2018 Kim EJ, Brown JA, Deng J, Hwang JL, Spina S, Miller ZA, DeMay MG, Valcour V, Karydas A, Ramos EM, Coppola G, Miller BL, Rosen HJ, Seeley WW, Grinberg LT
• A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder.
  Neurocase 2018 Hellmuth J, Milanini B, Masliah E, Tartaglia MC, Dunlop MB, Moore DJ, Javandel S, DeVaughn S, Valcour V
• Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities.
  The Journal of infectious diseases 2018 D'Antoni ML, Byron MM, Chan P, Sailasuta N, Sacdalan C, Sithinamsuwan P, Tipsuk S, Pinyakorn S, Kroon E, Slike BM, Krebs SJ, Khadka VS, Chalermchai T, Kallianpur KJ, Robb M, Spudich S, Valcour V, …
• Differences in Cognitive Function Between Women and Men With HIV.
  Journal of acquired immune deficiency syndromes (1999) 2018 Maki PM, Rubin LH, Springer G, Seaberg EC, Sacktor N, Miller EN, Valcour V, Young MA, Becker JT, Martin EM, Neuropsychology Working Groups of the Women's Interagency HIV Study and the Multicenter AIDS…
• Distribution of Human Immunodeficiency Virus (HIV) Ribonucleic Acid in Cerebrospinal Fluid and Blood Is Linked to CD4/CD8 Ratio During Acute HIV.
  The Journal of infectious diseases 2018 Chan P, Patel P, Hellmuth J, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Jagodzinski L, Krebs S, Ananworanich J, Valcour V, Spudich S, RV254/SEARCH 010 Study Team
• Structural and functional brain imaging in acute HIV.
  NeuroImage. Clinical 2018 Samboju V, Philippi CL, Chan P, Cobigo Y, Fletcher JLK, Robb M, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Paul R, Ananworanich J, Spudich S, Valcour V, SEARCH 010/RV254, RV304 …
• Carotid Artery Stiffness and Cognitive Decline Among Women With or at Risk for HIV Infection.
  Journal of acquired immune deficiency syndromes (1999) 2018 Huck DM, Hanna DB, Rubin LH, Maki P, Valcour V, Springer G, Xue X, Lazar J, Hodis HN, Anastos K, Kaplan RC, Kizer JR
• Structural Neuroimaging and Neuropsychologic Signatures in Children With Vertically Acquired HIV.
  The Pediatric infectious disease journal 2018 Paul R, Prasitsuebsai W, Jahanshad N, Puthanakit T, Thompson P, Aurpibul L, Hansudewechakul R, Kosalaraksa P, Kanjanavanit S, Ngampiyaskul C, Luesomboon W, Lerdlum S, Pothisri M, Visrutaratna P, …
• Characterization of Cellular Immune Responses in Thai Individuals With and Without HIV-Associated Neurocognitive Disorders.
  AIDS research and human retroviruses 2018 Ratto-Kim S, Schuetz A, Sithinamsuwan P, Barber J, Hutchings N, Lerdlum S, Fletcher JLK, Phuang-Ngern Y, Chuenarom W, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Sajjaweerawan C, Akapirat …
• Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques.
  Journal of virology 2018 Hsu DC, Sunyakumthorn P, Wegner M, Schuetz A, Silsorn D, Estes JD, Deleage C, Tomusange K, Lakhashe SK, Ruprecht RM, Lombardini E, Im-Erbsin R, Kuncharin Y, Phuang-Ngern Y, Inthawong D, Chuenarom W, …
• Acute Retroviral Syndrome Is Associated With High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, …
• Cognition, Emotional Health, and Immunological Markers in Children With Long-Term Nonprogressive HIV.
  Journal of acquired immune deficiency syndromes (1999) 2018 Paul R, Apornpong T, Prasitsuebsai W, Puthanakit T, Saphonn V, Aurpibul L, Kosalaraksa P, Kanjanavanit S, Luesomboon W, Ngampiyaskul C, Suwanlerk T, Chettra K, Shearer WT, Valcour V, Ananworanich J, …
• HIV-associated cognitive performance and psychomotor impairment in a Thai cohort on long-term cART.
  Journal of virus eradication 2018 Do TC, Kerr SJ, Avihingsanon A, Suksawek S, Klungkang S, Channgam T, Odermatt CC, Maek-A-Nantawat W, Ruxtungtham K, Ananworanich J, Valcour V, Reiss P, Wit FW
• Safety of lumbar puncture procedure in an international research setting during acute HIV infection.
  Journal of virus eradication 2018 Chan P, Hellmuth J, Colby D, Kroon E, Sacdalan C, Fletcher J, Patel P, Pinyakorn S, Valcour V, Ananworanich J, Spudich S
• Depression and Anxiety are Common in Acute HIV Infection and Associate with Plasma Immune Activation.
  AIDS and behavior 2017 Hellmuth J, Colby D, Valcour V, Suttichom D, Spudich S, Ananworanich J, Prueksakaew P, Sailasuta N, Allen I, Jagodzinski LL, Slike B, Ochi D, Paul R, RV254/SEARCH 010 Study Group
• Progressive Brain Atrophy Despite Persistent Viral Suppression in HIV Patients Older Than 60 Years.
  Journal of acquired immune deficiency syndromes (1999) 2017 Clifford KM, Samboju V, Cobigo Y, Milanini B, Marx GA, Hellmuth JM, Rosen HJ, Kramer JH, Allen IE, Valcour VG
• Variability in C-reactive protein is associated with cognitive impairment in women living with and without HIV: a longitudinal study.
  Journal of neurovirology 2017 Rubin LH, Benning L, Keating SM, Norris PJ, Burke-Miller J, Savarese A, Kumanan KN, Awadalla S, Springer G, Anastos K, Young M, Milam J, Valcour VG, Weber KM, Maki PM
• Cognitive trajectories over 4 years among HIV-infected women with optimal viral suppression.
  Neurology 2017 Rubin LH, Maki PM, Springer G, Benning L, Anastos K, Gustafson D, Villacres MC, Jiang X, Adimora AA, Waldrop-Valverde D, Vance DE, Bolivar H, Alden C, Martin EM, Valcour VG, Women's Interagency HIV …
• Perceived and post-traumatic stress are associated with decreased learning, memory, and fluency in HIV-infected women.
  AIDS (London, England) 2017 Rubin LH, Cook JA, Springer G, Weber KM, Cohen MH, Martin EM, Valcour VG, Benning L, Alden C, Milam J, Anastos K, Young MA, Gustafson DR, Sundermann EE, Maki PM
• Differentiating HIV-Associated Neurocognitive Disorders From Alzheimer's Disease: an Emerging Issue in Geriatric NeuroHIV.
  Current HIV/AIDS reports 2017 Milanini B, Valcour V
• High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection.
  Journal of acquired immune deficiency syndromes (1999) 2017 Kessing CF, Spudich S, Valcour V, Cartwright P, Chalermchai T, Fletcher JL, Takata H, Nichols C, Josey BJ, Slike B, Krebs SJ, Sailsuta N, Lerdlum S, Jagodzinski L, Tipsuk S, Suttichom D, Rattanamanee …
• Brief Report: CD14+ Enriched Peripheral Cells Secrete Cytokines Unique to HIV-Associated Neurocognitive Disorders.
  Journal of acquired immune deficiency syndromes (1999) 2017 Agsalda-Garcia MA, Sithinamsuwan P, Valcour VG, Chalermchai T, Tipsuk S, Kuroda J, Nakamura C, Ananworanich J, Zhang G, Schuetz A, Slike BM, Shiramizu B, SEARCH 011 Study Group
• Erratum to: Aging and Neurocognitive Functioning in HIV-Infected Women: a Review of the Literature Involving the Women's Interagency HIV Study.
  Current HIV/AIDS reports 2017 Vance DE, Rubin LH, Valcour V, Waldrop-Valverde D, Maki PM
• Psychiatric symptom burden in older people living with HIV with and without cognitive impairment: the UCSF HIV over 60 cohort study.
  AIDS care 2017 Milanini B, Catella S, Perkovich B, Esmaeili-Firidouni P, Wendelken L, Paul R, Greene M, Ketelle R, Valcour V
• White matter hyperintensities correlate to cognition and fiber tract integrity in older adults with HIV.
  Journal of neurovirology 2017 Watson C, Busovaca E, Foley JM, Allen IE, Schwarz CG, Jahanshad N, Nir TM, Esmaeili-Firidouni P, Milanini B, Rosen H, Carmichael OT, Thompson PM, Valcour VG
• Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.
  AIDS (London, England) 2017 Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S, RV254SEARCH 010, RV304SEARCH 013, and SEARCH 011 Study…
• Aging and Neurocognitive Functioning in HIV-Infected Women: a Review of the Literature Involving the Women's Interagency HIV Study.
  Current HIV/AIDS reports 2016 Vance DE, Rubin LH, Valcour V, Waldrop-Valverde D, Maki PM
• ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60.
  Journal of acquired immune deficiency syndromes (1999) 2016 Wendelken LA, Jahanshad N, Rosen HJ, Busovaca E, Allen I, Coppola G, Adams C, Rankin KP, Milanini B, Clifford K, Wojta K, Nir TM, Gutman BA, Thompson PM, Valcour V
• Neurologic signs and symptoms frequently manifest in acute HIV infection.
  Neurology 2016 Kamtchum-Tatuene J, Wan Sulaiman WA, Lekoubou A, Hellmuth J, Valcour V, Spudich S
• Monocyte Activation Is Associated With Worse Cognitive Performance in HIV-Infected Women With Virologic Suppression.
  The Journal of infectious diseases 2016 Imp BM, Rubin LH, Tien PC, Plankey MW, Golub ET, French AL, Valcour VG
• Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Sereti I, Krebs SJ, Phanuphak N, Fletcher JL, Slike B, Pinyakorn S, O'Connell RJ, Rupert A, Chomont N, Valcour V, Kim JH, Robb ML, Michael NL, Douek DC, Ananworanich J, Utay NS, RV254/SEARCH 010, …
• Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment.
  Scientific reports 2016 Corley MJ, Dye C, D'Antoni ML, Byron MM, Yo KL, Lum-Jones A, Nakamoto B, Valcour V, SahBandar I, Shikuma CM, Ndhlovu LC, Maunakea AK
• Extracting patterns of morphometry distinguishing HIV associated neurodegeneration from mild cognitive impairment via group cardinality constrained classification.
  Human brain mapping 2016 Zhang Y, Kwon D, Esmaeili-Firidouni P, Pfefferbaum A, Sullivan EV, Javitz H, Valcour V, Pohl KM
• Cognitive Impairment and Persistent CNS Injury in Treated HIV.
  Current HIV/AIDS reports 2016 Chan P, Hellmuth J, Spudich S, Valcour V
• Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
  PLoS pathogens 2016 Muir R, Metcalf T, Tardif V, Takata H, Phanuphak N, Kroon E, Colby DJ, Trichavaroj R, Valcour V, Robb ML, Michael NL, Ananworanich J, Trautmann L, Haddad EK, RV254/SEARCH010 RV304/SEARCH 013 Study …
• Liver Fibrosis Linked to Cognitive Performance in HIV and Hepatitis C.
  Journal of acquired immune deficiency syndromes (1999) 2016 Valcour VG, Rubin LH, Obasi MU, Maki PM, Peters MG, Levin S, Crystal HA, Young MA, Mack WJ, Cohen MH, Pierce CB, Adimora AA, Tien PC, Women's Interagency HIV Study Protocol Team
• Sex differences in soluble markers vary before and after the initiation of antiretroviral therapy in chronically HIV-infected individuals.
  AIDS (London, England) 2016 Krebs SJ, Slike BM, Sithinamsuwan P, Allen IE, Chalermchai T, Tipsuk S, Phanuphak N, Jagodzinski L, Kim JH, Ananworanich J, Marovich MA, Valcour VG, SEARCH 011 study team
• Neurologic signs and symptoms frequently manifest in acute HIV infection.
  Neurology 2016 Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich …
• Neuronal-Glia Markers by Magnetic Resonance Spectroscopy in HIV Before and After Combination Antiretroviral Therapy.
  Journal of acquired immune deficiency syndromes (1999) 2016 Sailasuta N, Ananworanich J, Lerdlum S, Sithinamsuwan P, Fletcher JL, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Chalermchai T, Catella S, Busovaca E, Desai A, Paul R, Valcour V, SEARCH …
• Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection.
  Journal of virus eradication 2016 Ananworanich J, Sacdalan CP, Pinyakorn S, Chomont N, de Souza M, Luekasemsuk T, Schuetz A, Krebs SJ, Dewar R, Jagodzinski L, Ubolyam S, Trichavaroj R, Tovanabutra S, Spudich S, Valcour V, Sereti I, …
• Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy.
  Journal of acquired immune deficiency syndromes (1999) 2015 Kore I, Ananworanich J, Valcour V, Fletcher JL, Chalermchai T, Paul R, Reynolds J, Tipsuk S, Ubolyam S, Rattanamanee S, Jagodzinski L, Kim J, Spudich S, RV254/SEARCH 010 Study Group
• Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV.
  PloS one 2015 Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JL, Kroon ED, Jagodzinski LL, Allen IE, Adams CL, Prueksakaew P, Slike BM, Hellmuth JM, Kim JH, Ananworanich J, SEARCH 010/RV 254 …
• Mapping abnormal subcortical brain morphometry in an elderly HIV+ cohort.
  NeuroImage. Clinical 2015 Wade BS, Valcour VG, Wendelken-Riegelhaupt L, Esmaeili-Firidouni P, Joshi SH, Gutman BA, Thompson PM
• Post-traumatic stress is associated with verbal learning, memory, and psychomotor speed in HIV-infected and HIV-uninfected women.
  Journal of neurovirology 2015 Rubin LH, Pyra M, Cook JA, Weber KM, Cohen MH, Martin E, Valcour V, Milam J, Anastos K, Young MA, Alden C, Gustafson DR, Maki PM
• Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-naïve HIV-infected Thais.
  Journal of neuroimmunology 2015 Ndhlovu LC, D'Antoni ML, Ananworanich J, Byron MM, Chalermchai T, Sithinamsuwan P, Tipsuk S, Ho E, Slike BM, Schuetz A, Zhang G, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Valcour V, SEARCH 011 study …
• Brain Imaging and Neurodevelopment in HIV-uninfected Thai Children Born to HIV-infected Mothers.
  The Pediatric infectious disease journal 2015 Jahanshad N, Couture MC, Prasitsuebsai W, Nir TM, Aurpibul L, Thompson PM, Pruksakaew K, Lerdlum S, Visrutaratna P, Catella S, Desai A, Kerr SJ, Puthanakit T, Paul R, Ananworanich J, Valcour VG, …
• Intrinsic network connectivity abnormalities in HIV-infected individuals over age 60.
  Journal of neurovirology 2015 Guha A, Wang L, Tanenbaum A, Esmaeili-Firidouni P, Wendelken LA, Busovaca E, Clifford K, Desai A, Ances BM, Valcour V
• Geriatric Syndromes in Older HIV-Infected Adults.
  Journal of acquired immune deficiency syndromes (1999) 2015 Greene M, Covinsky KE, Valcour V, Miao Y, Madamba J, Lampiris H, Cenzer IS, Martin J, Deeks SG
• Absence of Cerebrospinal Fluid Signs of Neuronal Injury Before and After Immediate Antiretroviral Therapy in Acute HIV Infection.
  The Journal of infectious diseases 2015 Peluso MJ, Valcour V, Ananworanich J, Sithinamsuwan P, Chalermchai T, Fletcher JL, Lerdlum S, Chomchey N, Slike B, Sailasuta N, Gisslén M, Zetterberg H, Spudich S, RV254/SEARCH 010 and SEARCH 011 …
• CNS reservoirs for HIV: implications for eradication.
  Journal of virus eradication 2015 Hellmuth J, Valcour V, Spudich S
• MAPPING ABNORMAL SUBCORTICAL BRAIN MORPHOMETRY IN AN ELDERLY HIV+ COHORT.
  Proceedings. IEEE International Symposium on Biomedical Imaging 2015 Wade BS, Valcour VG, Wendelken-Riegelhaupt L, Esmaeili-Firidouni P, Joshi SH, Wang Y, Thompson PM
• The association of perceived stress and verbal memory is greater in HIV-infected versus HIV-uninfected women.
  Journal of neurovirology 2015 Rubin LH, Cook JA, Weber KM, Cohen MH, Martin E, Valcour V, Milam J, Anastos K, Young MA, Alden C, Gustafson DR, Maki PM
• Subcortical shape and volume abnormalities in an elderly HIV+ cohort.
  Proceedings of SPIE--the International Society for Optical Engineering 2015 Wade BS, Valcour V, Busovaca E, Esmaeili-Firidouni P, Joshi SH, Wang Y, Thompson PM
• Human immunodeficiency virus (HIV) modulates the associations between insulin resistance and cognition in the current combination antiretroviral therapy (cART) era: a study of the Women's Interagency HIV Study (WIHS).
  Journal of neurovirology 2015 Valcour V, Rubin LH, Tien P, Anastos K, Young M, Mack W, Cohen M, Golub ET, Crystal H, Maki PM
• Association between brain volumes and HAND in cART-naïve HIV+ individuals from Thailand.
  Journal of neurovirology 2015 Heaps JM, Sithinamsuwan P, Paul R, Lerdlum S, Pothisri M, Clifford D, Tipsuk S, Catella S, Busovaca E, Fletcher JL, Raudabaugh B, Ratto-Kim S, Valcour V, Ananworanich J, SEARCH 007/011 study groups
• Cognitive function in women with HIV: findings from the Women's Interagency HIV Study.
  Neurology 2014 Maki PM, Rubin LH, Valcour V, Martin E, Crystal H, Young M, Weber KM, Manly J, Richardson J, Alden C, Anastos K
• Acute tubular nephropathy in a patient with acute HIV infection: review of the literature.
  AIDS research and therapy 2014 Ananworanich J, Datta AA, Fletcher JL, Townamchai N, Chomchey N, Kroon E, Sereti I, Valcour V, Kim JH
• Impact of the HIV Tat C30C31S dicysteine substitution on neuropsychological function in patients with clade C disease.
  Journal of neurovirology 2014 Paul RH, Joska JA, Woods C, Seedat S, Engelbrecht S, Hoare J, Heaps J, Valcour V, Ances B, Baker LM, Salminen LE, Stein DJ
• Interactions between ageing and NeuroAIDS.
  Current opinion in HIV and AIDS 2014 Hellmuth J, Milanini B, Valcour V
• The Montreal cognitive assessment to screen for cognitive impairment in HIV patients older than 60 years.
  Journal of acquired immune deficiency syndromes (1999) 2014 Milanini B, Wendelken LA, Esmaeili-Firidouni P, Chartier M, Crouch PC, Valcour V
• HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy.
  AIDS (London, England) 2014 Kallianpur KJ, Valcour VG, Lerdlum S, Busovaca E, Agsalda M, Sithinamsuwan P, Chalermchai T, Fletcher JL, Tipsuk S, Shikuma CM, Shiramizu BT, Ananworanich J, SEARCH 011 study group
• Neurodevelopmental outcomes in HIV-exposed-uninfected children versus those not exposed to HIV.
  AIDS care 2014 Kerr SJ, Puthanakit T, Vibol U, Aurpibul L, Vonthanak S, Kosalaraksa P, Kanjanavanit S, Hansudewechakul R, Wongsawat J, Luesomboon W, Ratanadilok K, Prasitsuebsai W, Pruksakaew K, van der Lugt J, Paul…
• Polypharmacy, drug-drug interactions, and potentially inappropriate medications in older adults with human immunodeficiency virus infection.
  Journal of the American Geriatrics Society 2014 Greene M, Steinman MA, McNicholl IR, Valcour V
• Practice effect and normative data of an HIV-specific neuropsychological testing battery among healthy Thais.
  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 2014 Sithinamsuwan P, Hutchings N, Ananworanich J, Wendelken L, Saengtawan P, Paul R, Chomchey N, Fletcher JL, Chalermchai T, Valcour V
• Anthropometric measures and cognition in middle-aged HIV-infected and uninfected women. The Women's Interagency HIV Study.
  Journal of neurovirology 2013 Gustafson DR, Mielke MM, Tien PC, Valcour V, Cohen M, Anastos K, Liu C, Pearce L, Golub ET, Minkoff H, Crystal HA
• HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients.
  PloS one 2013 Valcour VG, Ananworanich J, Agsalda M, Sailasuta N, Chalermchai T, Schuetz A, Shikuma C, Liang CY, Jirajariyavej S, Sithinamsuwan P, Tipsuk S, Clifford DB, Paul R, Fletcher JL, Marovich MA, Slike BM, …
• Ethnic differences in epidermal nerve fiber density.
  Muscle & nerve 2013 Shikuma CM, McArthur JC, Ebenezer GJ, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Valcour VG, Bennett K, Phanuphak N, SEARCH 014 Protocol Team
• Dementia in the oldest old: a multi-factorial and growing public health issue.
  Alzheimer's research & therapy 2013 Gardner RC, Valcour V, Yaffe K
• HIV, aging, and cognition: emerging issues.
  Topics in antiviral medicine 2013 Valcour VG
• Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study.
  The Pediatric infectious disease journal 2013 Puthanakit T, Ananworanich J, Vonthanak S, Kosalaraksa P, Hansudewechakul R, van der Lugt J, Kerr SJ, Kanjanavanit S, Ngampiyaskul C, Wongsawat J, Luesomboon W, Vibol U, Pruksakaew K, Suwarnlerk T, …
• HIV and recent illicit drug use interact to affect verbal memory in women.
  Journal of acquired immune deficiency syndromes (1999) 2013 Meyer VJ, Rubin LH, Martin E, Weber KM, Cohen MH, Golub ET, Valcour V, Young MA, Crystal H, Anastos K, Aouizerat BE, Milam J, Maki PM
• Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter.
  Neurology 2013 Kallianpur KJ, Shikuma C, Kirk GR, Shiramizu B, Valcour V, Chow D, Souza S, Nakamoto B, Sailasuta N
• Management of human immunodeficiency virus infection in advanced age.
  JAMA 2013 Greene M, Justice AC, Lampiris HW, Valcour V
• Deficits in self-awareness impact the diagnosis of asymptomatic neurocognitive impairment in HIV.
  AIDS research and human retroviruses 2013 Chiao S, Rosen HJ, Nicolas K, Wendelken LA, Alcantar O, Rankin KP, Miller B, Valcour V
• Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND.
  Journal of neurovirology 2013 Chalermchai T, Valcour V, Sithinamsuwan P, Pinyakorn S, Clifford D, Paul RH, Tipsuk S, Fletcher JL, Degruttola V, Ratto-Kim S, Hutchings N, Shikuma C, Ananworanich J, SEARCH 007 and 011 study groups
• Mapping white matter integrity in elderly people with HIV.
  Human brain mapping 2013 Nir TM, Jahanshad N, Busovaca E, Wendelken L, Nicolas K, Thompson PM, Valcour VG
• Global NeuroAIDS roundtable.
  Journal of neurovirology 2013 Joseph J, Achim CL, Boivin MJ, Brew BJ, Clifford DB, Colosi DA, Ellis RJ, Heaton RK, Gallo-Diop A, Grant I, Kanmogne GD, Kumar M, Letendre S, Marcotte TD, Nath A, Pardo CA, Paul RH, Pulliam L, …
• A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine.
  Antiviral therapy 2012 Phanuphak N, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Kerr SJ, Chomchey N, Hongchookiat P, Mathajittiphun P, Pinyakorn S, Rungrojrat P, Praihirunyakit P, Gerschenson M, Phanuphak P, …
• Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection.
  PloS one 2012 Sailasuta N, Ross W, Ananworanich J, Chalermchai T, DeGruttola V, Lerdlum S, Pothisri M, Busovaca E, Ratto-Kim S, Jagodzinski L, Spudich S, Michael N, Kim JH, Valcour V, RV254/SEARCH 010 protocol …
• Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders.
  Journal of clinical and experimental neuropsychology 2012 Heaps J, Valcour V, Chalermchai T, Paul R, Rattanamanee S, Siangphoe U, Sithinamsuwan P, Chairangsaris P, Nidhinandana S, Tipsuk S, Suttichom D, Fletcher J, Shikuma C, Ananworanich J
• Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.
  Antiviral therapy 2012 Shikuma CM, Nakamoto B, Shiramizu B, Liang CY, DeGruttola V, Bennett K, Paul R, Kallianpur K, Chow D, Gavegnano C, Hurwitz SJ, Schinazi RF, Valcour VG
• Neurocognitive impairment in patients randomized to second-line lopinavir/ritonavir-based antiretroviral therapy vs. lopinavir/ritonavir monotherapy.
  Journal of neurovirology 2012 Bunupuradah T, Chetchotisakd P, Jirajariyavej S, Valcour V, Bowonwattanuwong C, Munsakul W, Klinbuayaem V, Prasithsirikul W, Sophonphan J, Mahanontharit A, Hirschel B, Bhakeecheep S, Ruxrungtham K, …
• HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group.
  Journal of acquired immune deficiency syndromes (1999) 2012 High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, Deren S, Effros RB, Gebo K, Goronzy JJ, Justice AC, Landay A, Levin J, Miotti PG, Munk RJ, Nass H, Rinaldo CR, Shlipak MG, Tracy R, …
• Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals.
  Journal of neurovirology 2012 Nakamoto BK, Jahanshad N, McMurtray A, Kallianpur KJ, Chow DC, Valcour VG, Paul RH, Marotz L, Thompson PM, Shikuma CM
• Central nervous system viral invasion and inflammation during acute HIV infection.
  The Journal of infectious diseases 2012 Valcour V, Chalermchai T, Sailasuta N, Marovich M, Lerdlum S, Suttichom D, Suwanwela NC, Jagodzinski L, Michael N, Spudich S, van Griensven F, de Souza M, Kim J, Ananworanich J, RV254/SEARCH 010 Study…
• Impact of HIV and aging on neuropsychological function.
  Journal of neurovirology 2012 Wendelken LA, Valcour V
• Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.
  PloS one 2012 Ananworanich J, Schuetz A, Vandergeeten C, Sereti I, de Souza M, Rerknimitr R, Dewar R, Marovich M, van Griensven F, Sekaly R, Pinyakorn S, Phanuphak N, Trichavaroj R, Rutvisuttinunt W, Chomchey N, …
• Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study.
  Journal of acquired immune deficiency syndromes (1999) 2012 Crystal H, Kleyman I, Anastos K, Lazar J, Cohen M, Liu C, Pearce L, Golub E, Valcour V, Ho A, Strickler H, Peters M, Kovacs A, Holman S, Kreek MJ, Manly J
• Cognitive performance related to HIV-1-infected monocytes.
  The Journal of neuropsychiatry and clinical neurosciences 2012 Kusao I, Shiramizu B, Liang CY, Grove J, Agsalda M, Troelstrup D, Velasco VN, Marshall A, Whitenack N, Shikuma C, Valcour V
• Disrupted brain networks in the aging HIV+ population.
  Brain connectivity 2012 Jahanshad N, Valcour VG, Nir TM, Kohannim O, Busovaca E, Nicolas K, Thompson PM
• Failure to clear intra-monocyte HIV infection linked to persistent neuropsychological testing impairment after first-line combined antiretroviral therapy.
  Journal of neurovirology 2011 Shiramizu B, Ananworanich J, Chalermchai T, Siangphoe U, Troelstrup D, Shikuma C, De Grutolla V, Sithinamsuwan P, Praihirunkit P, Rattanamanee S, Valcour V, SEARCH 001.1 Study Group
• Evaluating cognitive impairment in the clinical setting: practical screening and assessment tools.
  Topics in antiviral medicine 2011 Valcour VG
• The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort.
  World journal of AIDS 2011 Shimizu SM, Chow DC, Valcour V, Masaki K, Nakamoto B, Kallianpur KJ, Shikuma C
• Regional cortical thinning associated with detectable levels of HIV DNA.
  Cerebral cortex (New York, N.Y. : 1991) 2011 Kallianpur KJ, Kirk GR, Sailasuta N, Valcour V, Shiramizu B, Nakamoto BK, Shikuma C
• Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women.
  Journal of neurovirology 2011 Crystal HA, Weedon J, Holman S, Manly J, Valcour V, Cohen M, Anastos K, Liu C, Mack WJ, Golub E, Lazar J, Ho A, Kreek MJ, Kaplan RC
• Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV Study.
  AIDS research and human retroviruses 2011 Valcour V, Maki P, Bacchetti P, Anastos K, Crystal H, Young M, Mack WJ, Cohen M, Golub ET, Tien PC
• Screening for cognitive impairment in human immunodeficiency virus.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011 Valcour V, Paul R, Chiao S, Wendelken LA, Miller B
• Impact of cerebrovascular disease on cognitive function in HIV-infected patients.
  Journal of acquired immune deficiency syndromes (1999) 2011 Nakamoto BK, Valcour VG, Kallianpur K, Liang CY, McMurtray A, Chow D, Kappenburg E, Shikuma CM
• Preventing dementia: is there hope for progress?
  American family physician 2011 Perissinotto CM, Valcour V
• Pathogenesis of HIV in the central nervous system.
  Current HIV/AIDS reports 2011 Valcour V, Sithinamsuwan P, Letendre S, Ances B
• The Effects of Age and HIV on Neuropsychological Performance.
  Journal of the International Neuropsychological Society : JINS 2010 Valcour V, Paul R, Neuhaus J, Shikuma C
• A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women.
  Addiction biology 2010 Crystal HA, Hamon S, Randesi M, Cook J, Anastos K, Lazar J, Liu C, Pearce L, Golub E, Valcour V, Weber KM, Holman S, Ho A, Kreek MJ
• Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa.
  Journal of neurovirology 2010 Joska JA, Combrinck M, Valcour VG, Hoare J, Leisegang F, Mahne AC, Myer L, Stein DJ
• Incident neuropathy in HIV-infected patients on HAART.
  AIDS research and human retroviruses 2010 Nakamoto BK, McMurtray A, Davis J, Valcour V, Watters MR, Shiramizu B, Chow DC, Kallianpur K, Shikuma CM
• HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications.
  Journal of leukocyte biology 2010 Valcour VG, Shiramizu BT, Shikuma CM
• Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohort Study.
  Journal of neurovirology 2010 Pumpradit W, Ananworanich J, Lolak S, Shikuma C, Paul R, Siangphoe U, Chaoniti N, Kaew-On P, Paris R, Ruxrungtham K, Valcour V, Southeast Asia Research Collaboration with Hawaii (SEARCH) 005 Protocol …
• Aging with HIV. Lessons from CROI 2009.
  Positively aware : the monthly journal of the Test Positive Aware Network 2009 Valcour V
• HIV DNA and cognition in a Thai longitudinal HAART initiation cohort: the SEARCH 001 Cohort Study.
  Neurology 2009 Valcour VG, Shiramizu BT, Sithinamsuwan P, Nidhinandana S, Ratto-Kim S, Ananworanich J, Siangphoe U, Kim JH, de Souza M, Degruttola V, Paul RH, Shikuma CM, Southeast Asia Research Collaboration with …
• Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection.
  HIV medicine 2009 Valcour V, Yeh TM, Bartt R, Clifford D, Gerschenson M, Evans SR, Cohen BA, Ebenezer GJ, Hauer P, Millar L, Gould M, Tran P, Shikuma C, Souza S, McArthur JC, AIDS Clinical Trials Group (ACTG) 5157 …
• Amount of HIV DNA in peripheral blood mononuclear cells is proportional to the severity of HIV-1-associated neurocognitive disorders.
  The Journal of neuropsychiatry and clinical neurosciences 2009 Shiramizu B, Williams AE, Shikuma C, Valcour V
• Frequency and characteristics of HIV-associated sensory neuropathy among HIV patients in Bangkok, Thailand.
  Journal of acquired immune deficiency syndromes (1999) 2008 Sithinamsuwan P, Punthanamongkol S, Valcour V, Onsanit S, Nidhinandana S, Thitivichianlert S, Shikuma C
• Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy.
  Journal of neurovirology 2008 Valcour V, Watters MR, Williams AE, Sacktor N, McMurtray A, Shikuma C
• Frequency of apolipoprotein E4 among older compared with younger HIV patients: support for detrimental effect of E4 on survival.
  Proceedings of the National Academy of Sciences of the United States of America 2008 Valcour V, Shiramizu B, Shikuma C
• Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study.
  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2008 McMurtray A, Nakamoto B, Shikuma C, Valcour V
• A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia.
  Nature clinical practice. Neurology 2008 Valcour V, Haman A, Cornes S, Lawall C, Parsa AT, Glaser C, Yagi S, Tihan T, Bhatnagar J, Geschwind M, Vanderbilt Continuing Medical Education online
• Expression of monocyte markers in HIV-1 infected individuals with or without HIV associated dementia and normal controls in Bangkok Thailand.
  Journal of neuroimmunology 2008 Ratto-Kim S, Chuenchitra T, Pulliam L, Paris R, Sukwit S, Gongwon S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Shiramizu BT, de Souza MS, Chitpatima ST, Sun B, Rempel H, Nitayaphan S, …
• Selegiline transdermal system (STS) for HIV-associated cognitive impairment: open-label report of ACTG 5090.
  HIV clinical trials 2007 Evans SR, Yeh TM, Sacktor N, Clifford DB, Simpson D, Miller EN, Ellis RJ, Valcour V, Marra CM, Millar L, Schifitto G, AIDS Clinical Trials Group and the Neurologic AIDS Research Consortium
• Updated research nosology for HIV-associated neurocognitive disorders.
  Neurology 2007 Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, …
• A multicenter trial of selegiline transdermal system for HIV-associated cognitive impairment.
  Neurology 2007 Schifitto G, Zhang J, Evans SR, Sacktor N, Simpson D, Millar LL, Hung VL, Miller EN, Smith E, Ellis RJ, Valcour V, Singer E, Marra CM, Kolson D, Weihe J, Remmel R, Katzenstein D, Clifford DB, ACTG …
• Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study.
  Cerebrovascular diseases (Basel, Switzerland) 2007 McMurtray A, Nakamoto B, Shikuma C, Valcour V
• Correlates of epidermal nerve fiber densities in HIV-associated distal sensory polyneuropathy.
  Neurology 2007 Zhou L, Kitch DW, Evans SR, Hauer P, Raman S, Ebenezer GJ, Gerschenson M, Marra CM, Valcour V, Diaz-Arrastia R, Goodkin K, Millar L, Shriver S, Asmuth DM, Clifford DB, Simpson DM, McArthur JC, NARC …
• Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals.
  Journal of neurovirology 2007 Sacktor N, Skolasky R, Selnes OA, Watters M, Poff P, Shiramizu B, Shikuma C, Valcour V
• Neuropsychological abnormalities in patients with dementia in CRF 01_AE HIV-1 infection.
  Neurology 2007 Valcour VG, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Ratto-Kim S, Apateerapong W, Shiramizu BT, Desouza MS, Chitpatima ST, Watt G, Chuenchitra T, Robertson KR, Paul RH, McArthur JC, Kim JH…
• HIV proviral DNA associated with decreased neuropsychological function.
  The Journal of neuropsychiatry and clinical neurosciences 2007 Shiramizu B, Paul R, Williams A, Shikuma C, Watters M, Grove J, Valcour V
• HIV DNA and dementia in treatment-naïve HIV-1-infected individuals in Bangkok, Thailand.
  International journal of medical sciences 2006 Shiramizu B, Ratto-Kim S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Watt G, deSouza M, Chuenchitra T, Sukwit S, Chitpatima S, Robertson K, Paul R, Shikuma C, Valcour V
• Insulin resistance is associated with cognition among HIV-1-infected patients: the Hawaii Aging With HIV cohort.
  Journal of acquired immune deficiency syndromes (1999) 2006 Valcour VG, Sacktor NC, Paul RH, Watters MR, Selnes OA, Shiramizu BT, Williams AE, Shikuma CM
• Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection--The Hawaii Aging with HIV Cohort.
  Journal of neurovirology 2006 Valcour V, Yee P, Williams AE, Shiramizu B, Watters M, Selnes O, Paul R, Shikuma C, Sacktor N
• HIV infection and dementia in older adults.
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006 Valcour V, Paul R
• Utility of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for dementia in a Japanese-American population.
  Hawaii medical journal 2006 Tokuhara KG, Valcour VG, Masaki KH, Blanchette PL
• Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease.
  The Journal of infectious diseases 2005 Kalayjian RC, Spritzler J, Pu M, Landay A, Pollard RB, Stocker V, Harthi LA, Gross BH, Francis IR, Fiscus SA, Tebas P, Bosch RJ, Valcour V, Lederman MM, Adult AIDS Clinical Trials Group 5015 and 5113 …
• Discordant plasma and cerebral spinal fluid cytokines/chemokines in relation to HIV-1-associated dementia.
  Cellular and molecular biology (Noisy-le-Grand, France) 2005 Killebrew DA, Troelstrup D, Valcour V, Williams A, Aguon J, Sapalo D, Shikuma C, Ratto-Kim S, Shiramizu B
• HIV-associated wasting in the era of highly active antiretroviral therapy: a syndrome of residual HIV infection in monocytes and macrophages?
  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005 Shikuma CM, Valcour VG, Ratto-Kim S, Williams AE, Souza S, Gerschenson M, Day L, Kim JH, Shiramizu B
• Circulating proviral HIV DNA and HIV-associated dementia.
  AIDS (London, England) 2005 Shiramizu B, Gartner S, Williams A, Shikuma C, Ratto-Kim S, Watters M, Aguon J, Valcour V
• Diabetes, insulin resistance, and dementia among HIV-1-infected patients.
  Journal of acquired immune deficiency syndromes (1999) 2005 Valcour VG, Shikuma CM, Shiramizu BT, Williams AE, Watters MR, Poff PW, Grove JS, Selnes OA, Sacktor NC
• Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii Aging with HIV Cohort.
  Journal of neuroimmunology 2004 Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes OA, Grove J, Liu Y, Abdul-Majid KB, Gartner S, Sacktor N
• Higher frequency of dementia in older HIV-1 individuals: the Hawaii Aging with HIV-1 Cohort.
  Neurology 2004 Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes O, Holck P, Grove J, Sacktor N
• HIV-associated dementia, mitochondrial dysfunction, and oxidative stress.
  Mitochondrion 2004 Valcour V, Shiramizu B
• Symptomatic distal sensory polyneuropathy in HIV after age 50.
  Neurology 2004 Watters MR, Poff PW, Shiramizu BT, Holck PS, Fast KM, Shikuma CM, Valcour VG
• Assessment of HIV-1 DNA copies per cell by real-time polymerase chain reaction.
  Frontiers in bioscience : a journal and virtual library 2004 Shiramizu B, Gartner S, Cho M, Liu Y, Pyron N, Valcour V, Shikuma C
• Cognitive impairment in older HIV-1-seropositive individuals: prevalence and potential mechanisms.
  AIDS (London, England) 2004 Valcour VG, Shikuma CM, Watters MR, Sacktor NC
• Tetanus immunity in long-term care facilities.
  Journal of the American Geriatrics Society 2003 Fernandes R, Valcour V, Flynn B, Masaki K, Blanchette P
• Self-reported driving, cognitive status, and physician awareness of cognitive impairment.
  Journal of the American Geriatrics Society 2002 Valcour VG, Masaki KH, Blanchette PL
• The detection of dementia in the primary care setting.
  Archives of internal medicine 2000 Valcour VG, Masaki KH, Curb JD, Blanchette PL
• Spontaneous ecchymoses due to paroxetine administration.
  The American journal of medicine 1998 Cooper TA, Valcour VG, Gibbons RB, O'Brien-Falls K