Victoire Gouirand, PhD
Postdoctoral Scholar
Dermatology
School of Medicine

Publications (16)

Top publication keywords:
Autoimmune DiseasesMethylenetetrahydrofolate Dehydrogenase (NADP)AminohydrolasesT-Lymphocytes, RegulatoryInflammationMultifunctional EnzymesMembrane GlycoproteinsPancreatic NeoplasmsKetone BodiesAutoimmunityOxo-Acid-LyasesImmune Privilege3-Hydroxybutyric AcidProline OxidaseReceptors, Lymphocyte Homing

• Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche.
  Science immunology 2024 Cohen JN, Gouirand V, Macon CE, Lowe MM, Boothby IC, Moreau JM, Gratz IK, Stoecklinger A, Weaver CT, Sharpe AH, Ricardo-Gonzalez RR, Rosenblum MD
• 012 Tissue-specific manipulation of regulatory T cells reveals the skin to be a site of immune tolerance.
  Journal of Investigative Dermatology 2022 J. Cohen, J. Moreau, V. Gouirand, C. Macon, I. Boothby, I. Gratz, A. Stoecklinger, C. Weaver, A. Sharpe, R. Ricardo-Gonzalez, M. Rosenblum
• Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression.
  The EMBO journal 2022 Gouirand V, Gicquel T, Lien EC, Jaune-Pons E, Da Costa Q, Finetti P, Metay E, Duluc C, Mayers JR, Audebert S, Camoin L, Borge L, Rubis M, Leca J, Nigri J, Bertucci F, Dusetti N, Iovanna JL, Tomasini R…
• MTHFD2, metabolic mastermind of CD4+ T cell destiny.
  Science immunology 2022 Gouirand V, Rosenblum MD
• Tregs and inflammation-bring it on!
  Science immunology 2021 Gouirand V, Rosenblum MD

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• Layilin Anchors Regulatory T Cells in Skin.
  Journal of immunology (Baltimore, Md. : 1950) 2021 Mehta P, Gouirand V, Boda DP, Zhang J, Gearty SV, Zirak B, Lowe MM, Clancy S, Boothby I, Mahuron KM, Fries A, Krummel MF, Mankoo P, Chang HW, Liu J, Moreau JM, Scharschmidt TC, Daud A, Kim E, Neuhaus …
• Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation.
  Science immunology 2021 Moreau JM, Dhariwala MO, Gouirand V, Boda DP, Boothby IC, Lowe MM, Cohen JN, Macon CE, Leech JM, Kalekar LA, Scharschmidt TC, Rosenblum MD
• Regulatory T Cells and Inflammatory Mediators in Autoimmune Disease.
  The Journal of investigative dermatology 2021 Gouirand V, Habrylo I, Rosenblum MD
• T-Cell Adhesion in Healthy and Inflamed Skin.
  JID innovations : skin science from molecules to population health 2021 Moreau JM, Gouirand V, Rosenblum MD
• Layilin augments integrin activation to promote antitumor immunity.
  The Journal of experimental medicine 2020 Mahuron KM, Moreau JM, Glasgow JE, Boda DP, Pauli ML, Gouirand V, Panjabi L, Grewal R, Luber JM, Mathur AN, Feldman RM, Shifrut E, Mehta P, Lowe MM, Alvarado MD, Marson A, Singer M, Wells J, Jupp R, …
• Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.
  Cell metabolism 2019 Goossens P, Rodriguez-Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, Ulas T, Papantonopoulou O, Van Eck M, Auphan-Anezin N, Bebien M, Verthuy C, Vu Manh TP, Turner M, Dalod M, Schultze JL, …
• Influence of the Tumor Microenvironment on Cancer Cells Metabolic Reprogramming.
  Frontiers in oncology 2018 Gouirand V, Guillaumond F, Vasseur S
• Fountain of youth of pancreatic cancer cells: the extracellular matrix.
  Cell death discovery 2018 Gouirand V, Vasseur S
• Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions.
  Nature communications 2017 Olivares O, Mayers JR, Gouirand V, Torrence ME, Gicquel T, Borge L, Lac S, Roques J, Lavaut MN, Berthezène P, Rubis M, Secq V, Garcia S, Moutardier V, Lombardo D, Iovanna JL, Tomasini R, Guillaumond F…
• Study of metabolic reprogramming during pancreatic cancer progression: Metabolism of branched chain amino acids.
  Pancreatology 2017 Victoire Gouirand, Q. Da Costa, G. Bidaut, S. Beloribi-Djefaflia, T. Gicquel, J. Roques, J. Iovanna, F. Guillaumond-Marchai, S. Vasseur
• Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
  Proceedings of the National Academy of Sciences of the United States of America 2015 Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O, Lac S, Borge L, Roques J, Gayet O, Pinault M, Guimaraes C, Nigri J, Loncle C, Lavaut MN, Garcia S, Tailleux A, Staels B, Calvo E,…