Velmurugan Jayabal, MBBS, PhD
Specialist
Radiology
School of Medicine

There, he received comprehensive clinical training in epilepsy, focusing his research on innovative electrophysiological biomarkers such as high-frequency oscillations and functional connectivity to pinpoint the epileptogenic zone and forecast outcomes. Additionally, Dr. Jayabal was awarded a Fulbright Fellowship to advance his research during his M.D-Ph.D.

Following his doctoral studies, Dr. Jayabal pursued post-doctoral research at Aix-Marseille University and La Timone Hospital, where he investigated the efficacy of source reconstruction and network retrieval, as well as the relationship between magnetoencephalography (MEG) and intracranial stereoelectroencephalography (SEEG) signals in epilepsy patients.

At UCSF, Dr. Jayabal's work focuses on MEG/EEG imaging of brain activity and functional connectivity, including detection, source localization of epileptiform events, functional mapping, interpretation of neurophysiology findings, and generating MSI reports. He also provides training to staff and students on best practices and interpretation of MEG and EEG data collection, processing, and analysis.

Dr. Jayabal's research primarily revolves around investigating physiological and pathological network and substrate alterations in patients with epilepsy, brain tumors, dementia, and other neurological disorders. A significant portion of his research endeavors centers on utilizing MEG brain imaging to identify biomarkers, improve the localization of epileptogenic zones, and understand the temporospatial profile in patients with neuropsychiatric disorders.

• EEG-based P300 in mesial temporal lobe epilepsy and its correlation with cognitive functions: A case-control study.
  Epilepsy & behavior : E&B 2021 Mukheem Mudabbir MA, Mundlamuri RC, Aravind KR, Narayanan M, Alladi S, Shivashankar N, Kenchaiah R, Asranna A, Viswanathan LG, Bhargava GK, Velmurugan J, Thennarasu K, Rajan J, Kulanthaivelu K, …
• Detection and localization of deep sources in magnetoencephalography: A review
  Current Opinion in Biomedical Engineering 2021 Christian-GeorgeBénar, JayabalVelmurugan, Victor J.López-Madrona, FrancescaPizzo, Jean-MichelBadier
• Magnetic source imaging in presurgical evaluation of paediatric focal drug-resistant epilepsy and its predictive value of surgical outcome in lesional cases: A single-centre experience from South India.
  Seizure 2021 Gautham B, Abdulhak A, Mundlamuri RC, Narayanan M, Jayabal V, Kenchaiah R, Asranna A, Dawn BR, Jitender S, Nagaraj C, Mangalore S, Karthik K, Sadashiva N, Mahadevan A, Rajeswaran J, Kumar K, …
• Content-Based Estimation of Brain MRI Tilt in Three Orthogonal Directions.
  Journal of digital imaging 2021 Prabhu P, Karunakar AK, Sinha S, Mariyappa N, Bhargava GK, Velmurugan J, Anitha H
• Seizure detection and epileptogenic zone localisation on heavily skewed MEG data using RUSBoost machine learning technique.
  The International journal of neuroscience 2020 Bhanot N, Mariyappa N, Anitha H, Bhargava GK, Velmurugan J, Sinha S
• P300 in mesial temporal lobe epilepsy and its correlation with cognition - A MEG based prospective case-control study.
  Epilepsy & behavior : E&B 2020 Mukheem Mudabbir MA, Mundlamuri RC, Mariyappa N, Aravind Kumar R, Velmurugan J, Bhargava GK, Suvarna A, Shivashankar N, Raghavendra K, Asranna A, Thennarasu K, Jamuna R, Rose Dawn B, Saini J, Sinha S
• Magnetoencephalography imaging of high frequency oscillations strengthens presurgical localization and outcome prediction.
  Brain : a journal of neurology 2019 Velmurugan J, Nagarajan SS, Mariyappa N, Mundlamuri RC, Raghavendra K, Bharath RD, Saini J, Arivazhagan A, Rajeswaran J, Mahadevan A, Malla BR, Satishchandra P, Sinha S
• Evaluation of a dual signal subspace projection algorithm in magnetoencephalographic recordings from patients with intractable epilepsy and vagus nerve stimulators.
  NeuroImage 2018 Cai C, Xu J, Velmurugan J, Knowlton R, Sekihara K, Nagarajan SS, Kirsch H
• T115. Magnetoencephalographic imaging of ictal high-frequency oscillations (80–200 Hz) in medically refractory epilepsy: Clinical Neurophysiology
  T115. Magnetoencephalographic imaging of ictal high-frequency oscillations (80–200 Hz) in medically refractory epilepsy: Clinical Neurophysiology 2018 Velmurugan Jayabal, Srikantan Nagarajan, Mariyappa Narayanan, Ravi Shankar, Thennarasu Kandavel, Ravindranadh C. Mundlamuri, Raghavendra Kenchaiah, Rose Dawn Bharath, Jitender Saini, Arivazhagan …
• Association of default mode network (DMN) regions at absence seizure onset unconstrained by their frequency confinement : Epilepsia
  Association of default mode network (DMN) regions at absence seizure onset unconstrained by their frequency confinement : Epilepsia 2017 Sanjib Sinha, Velmurugan Jayabal, N Mariyappa, V Gadad, P Satishchandra, Srikantan Nagarajan
• Source analysis of epileptiform discharges in absence epilepsy using Magnetoencephalography (MEG).
  Epilepsy research 2017 Gadad V, Sinha S, Mariyappa N, Velmurugan J, Chaitanya G, Saini J, Thennarasu K, Satishchandra P
• Magnetoencephalographic imaging of ictal high-frequency oscillations (80-200 Hz) in pharmacologically resistant focal epilepsy.
  Epilepsia 2017 Velmurugan J, Nagarajan SS, Mariyappa N, Ravi SG, Thennarasu K, Mundlamuri RC, Raghavendra K, Bharath RD, Saini J, Arivazhagan A, Rajan J, Mahadevan A, Rao MB, Satishchandra P, Sinha S
• Role of magnetoencephalography and stereo-electroencephalography in the presurgical evaluation in patients with drug-resistant epilepsy.
  Neurology India 2017 Jayabal V, Pillai A, Sinha S, Mariyappa N, Satishchandra P, Gopinath S, Radhakrishnan K
• Source localization of epileptiform discharges in juvenile myoclonic epilepsy (JME) using magnetoencephalography (MEG).
  Epilepsy research 2016 Gadad V, Sinha S, Mariyappa N, Chaithanya G, Jayabal V, Saini J, Thennarasu K, Satishchandra P
• Combined MEG-EEG source localisation in patients with sub-acute sclerosing pan-encephalitis.
  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2016 Velmurugan J, Sinha S, Nagappa M, Mariyappa N, Bindu PS, Ravi GS, Hazra N, Thennarasu K, Ravi V, Taly AB, Satishchandra P
• Ictal Generalized EEG Attenuation (IGEA) and hypopnea in a child with occipital type 1 cortical dysplasia - Is it a biomarker for SUDEP?
  Annals of Indian Academy of Neurology 2015 Chaitanya G, Santosh NS, Velmurugan J, Arivazhagan A, Bharath RD, Mahadevan A, Nagappa M, Bindu PS, Rao MB, Taly AB, Satishchandra P, Sinha S
• Magnetoencephalography recording and analysis.
  Annals of Indian Academy of Neurology 2014 Velmurugan J, Sinha S, Satishchandra P