Uttam Shrestha, PhD
Specialist
Radiology
School of Medicine

Publications (41)

Top publication keywords:
Coronary CirculationHeart TransplantationCardiac-Gated Single-Photon Emission Computer-Assisted TomographyTomography, Emission-Computed, Single-PhotonRubidium RadioisotopesPositron-Emission TomographyOrganotechnetium CompoundsOrganophosphorus CompoundsCoronary Artery DiseaseFeasibility StudiesRadiopharmaceuticalsMyocardiumBlood Flow VelocityMyocardial Perfusion ImagingHeart

• Evaluation of motion correction on myocardial [18F]F-AraG PET uptake using data-driven respiratory gating.
  Medical physics 2026 Kim H, Tang R, Shrestha UM, Chae HD, Levi J, Flavell RR, Seo Y
• Mitochondrial Imaging Detects Early Cardiac Changes Following Cancer Immunotherapy.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2026 Chae HD, Shrestha U, Das M, Vasanawala MS, Behl D, Davar D, Srinivas S, Colevas AD, Sunwoo JB, Del Mar N, Pierini M, Guillen M, Garcia J, Omidvari N, Gupta N, Cabrera H, Blecha J, Cherry SR, …
• Mitochondrial Imaging Detects Early Cardiac Responses to Cancer Immunotherapy.
  medRxiv : the preprint server for health sciences 2025 Chae HD, Shrestha U, Das M, Vasanawala MS, Behl D, Davar D, Srinivas S, Colevas AD, Sunwoo J, Del Mar N, Pierini M, Guillen M, Garcia J, Omidvari N, Gupta N, Cabrera H, Blecha J, Cherry SR, …
• 224eP Systemic mitochondrial alterations in patients with advanced non-small lung cancer revealed by [18F]F-AraG PET imaging.
  Annals of Oncology 2025 J. Levi, U. Shrestha, M. Das, M. Vasanawala, D. Behl, J. Sayre, H. Cabrera, N. Del Mar, M. Gullen, M. Pierini, J. Blecha, H. VanBrocklin, Y. Seo, H-D. Chae
• A Feasibility Study of [18F]F-AraG Positron Emission Tomography (PET) for Cardiac Imaging-Myocardial Viability in Ischemia-Reperfusion Injury Model.
  Molecular imaging and biology 2024 Shrestha UM, Chae HD, Fang Q, Lee RJ, Packiasamy J, Huynh L, Blecha J, Huynh TL, VanBrocklin HF, Levi J, Seo Y

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• Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection.
  Science translational medicine 2024 Peluso MJ, Ryder D, Flavell RR, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez AE, Buitrago M, Tai V, Shrestha U, Lu S, …
• A feasibility study of [18F]F-AraG positron emission tomography (PET) for cardiac imaging - myocardial viability in ischemia-reperfusion injury model.
  Research square 2024 Shrestha U, Chae HD, Fang Q, Lee RJ, Packiasamy J, Huynh L, Blecha J, Huynh TL, VanBrocklin HF, Levi J, Seo Y
• Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19.
  medRxiv : the preprint server for health sciences 2023 Peluso MJ, Ryder D, Flavell R, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez A, Buitrago M, Tai V, Shrestha U, Lu S, …
• Biodiversity: the overlooked source of human health.
  Trends in molecular medicine 2022 Linhares Y, Kaganski A, Agyare C, Kurnaz IA, Neergheen V, Kolodziejczyk B, Kedra M, Wahajuddin M, El-Youssf L, Dela Cruz TE, Baran Y, Pešic M, Shrestha U, Bakiu R, Allard PM, Rybtsov S, Pieri M, …
• Monte Carlo Simulation and Reconstruction: Assessment of Myocardial Perfusion Imaging of Tracer Dynamics With Cardiac Motion Due to Deformation and Respiration Using Gamma Camera With Continuous Acquisition.
  Frontiers in cardiovascular medicine 2022 Huh Y, Shrestha UM, Gullberg GT, Seo Y
• X-ray bi-prism interferometry-A design study of proposed novel hardware.
  Medical physics 2021 Gullberg GT, Shrestha U, Kim SJW, Seo Y, Fuller M
• Novel Methodology for Measuring Regional Myocardial Efficiency.
  IEEE transactions on medical imaging 2021 Gullberg GT, Shrestha UM, Veress AI, Segars WP, Liu J, Ordovas K, Seo Y
• Assessment of late-term progression of cardiac allograft vasculopathy in patients with orthotopic heart transplantation using quantitative cardiac 82Rb PET.
  The international journal of cardiovascular imaging 2020 Shrestha UM, Sciammarella M, Pampaloni MH, Botvinick EH, Gullberg GT, DeMarco T, Seo Y
• Multiresolution spatiotemporal mechanical model of the heart as a prior to constrain the solution for 4D models of the heart.
  Proceedings of SPIE--the International Society for Optical Engineering 2019 Gullberg GT, Veress AI, Shrestha UM, Liu J, Ordovas K, Segars WP, Seo Y
• PET imaging of glucose and fatty acid metabolism for NAFLD patients.
  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2018 Gullberg GT, Shrestha UM, Seo Y
• Tensor Tomography of Dark Field Scatter using X-ray Interferometry with Bi-prisms.
  IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium 2018 Gullberg GT, Fuller M, Shrestha U, Seo Y
• Comparison of sparse domain approaches for 4D SPECT dynamic image reconstruction.
  Medical physics 2018 Mitra D, Abdalah M, Boutchko R, Chang H, Shrestha U, Botvinick E, Seo Y, Gullberg GT
• Dynamic cardiac PET imaging: Technological improvements advancing future cardiac health.
  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2018 Gullberg GT, Shrestha UM, Seo Y
• Tensor Tomography of Dark Field Scatter using X-ray Interferometry with Bi-prisms
  Proceedings IEEE Nuclear Science Symposium and Medical Imaging 2017 Grant T. Gullberg, Michael Fuller, Uttam Shrestha, Youngho Seo
• A combined static-dynamic single-dose imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT.
  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2017 Sciammarella M, Shrestha UM, Seo Y, Gullberg GT, Botvinick EH
• Noninvasive PET quantitative myocardial blood flow with regadenoson for assessing cardiac allograft vasculopathy in orthotopic heart transplantation patients.
  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2017 Pampaloni MH, Shrestha UM, Sciammarella M, Seo Y, Gullberg GT, Botvinick EH
• Myocardial Blood Flow as a Biomarker.
  Biomarkers in Cardiovascular Disease 2016 Uttam Shrestha, Youngho Seo
• Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation.
  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2015 Shrestha U, Sciammarella M, Alhassen F, Yeghiazarians Y, Ellin J, Verdin E, Boyle A, Seo Y, Botvinick EH, Gullberg GT
• Image reconstruction in higher dimensions: myocardial perfusion imaging of tracer dynamics with cardiac motion due to deformation and respiration.
  Physics in medicine and biology 2015 Shrestha UM, Seo Y, Botvinick EH, Gullberg GT
• Myocardial Blood Flow as a Biomarker.
  Biomarkers in Cardiovascular Disease 2015 Uttam Shrestha, Youngho Seo
• Handling Big Data in Medical Imaging: Iterative Reconstruction with Large-Scale Automated Parallel Computation.
  IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium 2014 Lee JH, Yao Y, Shrestha U, Gullberg GT, Seo Y
• Multipinhole collimator with 20 apertures for a brain SPECT application.
  Medical physics 2014 Lee TC, Ellin JR, Huang Q, Shrestha U, Gullberg GT, Seo Y
• Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT.
  IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium 2014 Shrestha U, Botvinick EH, Yeghiazarians Y, Seo Y, Gullberg GT
• The Effect of Magnetic Field on Positron Range and Spatial Resolution in an Integrated Whole-Body Time-Of-Flight PET/MRI System.
  IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium 2014 Huang SY, Savic D, Yang J, Shrestha U, Seo Y
• Liver and Background Removal in Dynamic Cardiac SPECT
  J. Nuc. Med. 2014 M Abdalah, R Boutchko, D Mitra, U Shrestha, Y Seo, E Botvinick, G Gullberg
• Axonal transport: how high microtubule density can compensate for boundary effects in small-caliber axons.
  Biophysical journal 2014 Wortman JC, Shrestha UM, Barry DM, Garcia ML, Gross SP, Yu CC
• Design and performance evaluation of a 20-aperture multipinhole collimator for myocardial perfusion imaging applications.
  Physics in medicine and biology 2013 Bowen JD, Huang Q, Ellin JR, Lee TC, Shrestha U, Gullberg GT, Seo Y
• A RARE CASE OF HYPOGASTRIC OMPHALOCOELE WITH SACRAL MENINGOCOELE.
  Journal of Evolution of Medical and Dental Sciences 2013 Anand Mishra, Shamsher Shrestha, Mandavi Singh, Uttam Shrestha
• Fragmentation, domain formation and atom number fluctuations of a two-species Bose–Einstein condensate in an optical lattice
  New J. Phys. 2012 Uttam Shrestha, Janne Ruostekoski
• Antiferromagnetism in a bosonic mixture of rubidium (Rb87) and potassium (K41)
  Phys. Rev. A 2010 Uttam Shrestha
• Correlated bosons in a one-dimensional optical lattice: Effects of the trapping potential and of quasiperiodic disorder
  Phys. Rev. A 2010 Uttam Shrestha, Michele Modugno
• Pulsating and persistent vector solitons in a Bose-Einstein condensate in a lattice upon phase separation instability.
  Physical review letters 2009 Shrestha U, Javanainen J, Ruostekoski J
• Quantum dynamics of instability-induced pulsations of a Bose-Einstein condensate in an optical lattice
  Phys. Rev. A 2009 Uttam Shrestha, Juha Javanainen, Janne Ruostekoski
• Nonlinear phenomenology from quantum mechanics: soliton in a lattice.
  Physical review letters 2008 Javanainen J, Shrestha U
• Pulsating instability of a Bose-Einstein condensate in an optical lattice.
  Physical review letters 2008 Shrestha U, Kostrun M, Javanainen J
• Collective molecule formation in a degenerate Fermi gas via a Feshbach resonance.
  Physical review letters 2004 Javanainen J, Kostrun M, Zheng Y, Carmichael A, Shrestha U, Meinel PJ, Mackie M, Dannenberg O, Suominen KA