Ursula Lang, MD, PhD
Assistant Professor
Pathology
School of Medicine
Publications (33)
Top publication keywords:
MelanocytesUbiquitin ThiolesteraseKruppel-Like Transcription FactorsNevus, BlueProto-Oncogene ProteinsNevus, Epithelioid and Spindle CellCyclin-Dependent Kinase Inhibitor p21Tumor Suppressor ProteinsTranscriptional ActivationMelanomaSkin NeoplasmsNevus, PigmentedCentrosomeHepatic Stellate CellsCilia
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Epigenetic reprogramming shapes the cellular landscape of schwannoma.
Nature communications 2024 Liu SJ, Casey-Clyde T, Cho NW, Swinderman J, Pekmezci M, Dougherty MC, Foster K, Chen WC, Villanueva-Meyer JE, Swaney DL, Vasudevan HN, Choudhury A, Pak J, Breshears JD, Lang UE, Eaton CD, Hiam-Galvez… -
Painful Mucosal Ulcerations in a Patient With HIV.
JAMA dermatology 2022 Kusari A, Lang UE, Chang AY -
LZTS2: A novel and independent prognostic biomarker for clear cell renal cell carcinoma.
Pathology, research and practice 2022 Peng Y, Greenland NY, Lang UE, Stohr BA -
BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB.
eLife 2021 McNeal AS, Belote RL, Zeng H, Urquijo M, Barker K, Torres R, Curtin M, Shain AH, Andtbacka RH, Holmen S, Lum DH, McCalmont TH, VanBrocklin MW, Grossman D, Wei ML, Lang UE, Judson-Torres RL -
A 21-Year-Old Woman With Joint Pain and Skin Ulceration.
Arthritis care & research 2021 French S, Lang UE, Margaretten M
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Human melanocyte development and melanoma dedifferentiation at single-cell resolution.
Nature cell biology 2021 Belote RL, Le D, Maynard A, Lang UE, Sinclair A, Lohman BK, Planells-Palop V, Baskin L, Tward AD, Darmanis S, Judson-Torres RL -
Association of Facial Pustular Neutrophilic Eruption With Messenger RNA-1273 SARS-CoV-2 Vaccine.
JAMA dermatology 2021 Merrill ED, Kashem SW, Amerson EH, Pincus LB, Lang UE, Shinkai K, Chang AY -
Primary Cilia Are Preserved in Cellular Blue and Atypical Blue Nevi and Lost in Blue Nevus-like Melanoma.
The American journal of surgical pathology 2021 Sheahon KM, Jankowski T, Yeh I, North JP, Pincus LB, LeBoit PE, McCalmont TH, Lang UE -
BAP1-inactivated melanocytic tumors show prominent centrosome amplification and associated loss of primary cilia.
Journal of cutaneous pathology 2021 Ye J, Sheahon KM, LeBoit PE, McCalmont TH, Lang UE -
Herpes simplex virus-2 associated with a large fungating penile mass.
Urology case reports 2021 Bowman MS, Lang UE, Leslie KS, Amend G, Breyer BN -
Meningioma cells express primary cilia but do not transduce ciliary Hedgehog signals.
Acta neuropathologica communications 2020 Findakly S, Choudhury A, Daggubati V, Pekmezci M, Lang UE, Raleigh DR -
Clinical Implications of Primary Cilia in Skin Cancer.
Dermatology and therapy 2020 Choudhury A, Neumann NM, Raleigh DR, Lang UE -
Ciliation Index Is a Useful Diagnostic Tool in Challenging Spitzoid Melanocytic Neoplasms.
The Journal of investigative dermatology 2020 Lang UE, Torres R, Cheung C, Vladar EK, McCalmont TH, Kim J, Judson-Torres RL -
Use of the Ciliation Index to Distinguish Invasive Melanoma From Associated Conventional Melanocytic Nevi.
The American Journal of dermatopathology 2020 Lang UE, Love NR, Cheung C, McCalmont TH, Kim J -
MicroRNA Ratios Distinguish Melanomas from Nevi.
The Journal of investigative dermatology 2019 Torres R, Lang UE, Hejna M, Shelton SJ, Joseph NM, Shain AH, Yeh I, Wei ML, Oldham MC, Bastian BC, Judson-Torres RL -
Depletion of primary cilium in acral melanoma.
Journal of cutaneous pathology 2019 Love NR, Lang UE, Cheung C, Kim J -
Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory.
Cell 2019 Poggio M, Hu T, Pai CC, Chu B, Belair CD, Chang A, Montabana E, Lang UE, Fu Q, Fong L, Blelloch R -
Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation.
Cancer cell 2018 Zeng H, Jorapur A, Shain AH, Lang UE, Torres R, Zhang Y, McNeal AS, Botton T, Lin J, Donne M, Bastian IN, Yu R, North JP, Pincus L, Ruben BS, Joseph NM, Yeh I, Bastian BC, Judson RL -
Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi.
Nature communications 2017 Yeh I, Lang UE, Durieux E, Tee MK, Jorapur A, Shain AH, Haddad V, Pissaloux D, Chen X, Cerroni L, Judson RL, LeBoit PE, McCalmont TH, Bastian BC, de la Fouchardière A -
Molecular Melanoma Diagnosis Update: Gene Fusion, Genomic Hybridization, and Massively Parallel Short-Read Sequencing.
Clinics in laboratory medicine 2017 Lang UE, Yeh I, McCalmont TH -
Loss of primary cilia correlates with cytologic severity in dysplastic melanocytic nevi.
Journal of cutaneous pathology 2015 Lang UE, Cheung C, Vladar EK, Swetter SM, Kim J -
Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis.
Journal of hepatology 2013 Bechmann LP, Vetter D, Ishida J, Hannivoort RA, Lang UE, Kocabayoglu P, Fiel MI, Muñoz U, Patman GL, Ge F, Yakar S, Li X, Agius L, Lee YM, Zhang W, Hui KY, Televantou D, Schwartz GJ, LeRoith D, Berk … -
Reduced hepatic stellate cell expression of Kruppel-like factor 6 tumor suppressor isoforms amplifies fibrosis during acute and chronic rodent liver injury.
Hepatology (Baltimore, Md.) 2012 Ghiassi-Nejad Z, Hernandez-Gea V, Woodrell C, Lang UE, Dumic K, Kwong A, Friedman SL -
GSK3β phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21.
Oncogene 2012 Lang UE, Kocabayoglu P, Cheng GZ, Ghiassi-Nejad Z, Muñoz U, Vetter D, Eckstein DA, Hannivoort RA, Walsh MJ, Friedman SL -
Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene.
Circulation research 2012 Garrido-Martín EM, Blanco FJ, Roquè M, Novensà L, Tarocchi M, Lang UE, Suzuki T, Friedman SL, Botella LM, Bernabéu C -
Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1.
Molecular cancer research : MCR 2012 Muñoz Ú, Puche JE, Hannivoort R, Lang UE, Cohen-Naftaly M, Friedman SL -
Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease.
Hepatology (Baltimore, Md.) 2012 Bechmann LP, Gastaldelli A, Vetter D, Patman GL, Pascoe L, Hannivoort RA, Lee UE, Fiel I, Muñoz U, Ciociaro D, Lee YM, Buzzigoli E, Miele L, Hui KY, Bugianesi E, Burt AD, Day CP, Mari A, Agius L, … -
Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression.
Hepatology (Baltimore, Md.) 2012 Jiao J, Sastre D, Fiel MI, Lee UE, Ghiassi-Nejad Z, Ginhoux F, Vivier E, Friedman SL, Merad M, Aloman C -
A polymorphism that delays fibrosis in hepatitis C promotes alternative splicing of AZIN1, reducing fibrogenesis.
Hepatology (Baltimore, Md.) 2011 Paris AJ, Snapir Z, Christopherson CD, Kwok SY, Lee UE, Ghiassi-Nejad Z, Kocabayoglu P, Sninsky JJ, Llovet JM, Kahana C, Friedman SL -
Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation.
Hepatology (Baltimore, Md.) 2011 Tarocchi M, Hannivoort R, Hoshida Y, Lee UE, Vetter D, Narla G, Villanueva A, Oren M, Llovet JM, Friedman SL -
Mechanisms of hepatic fibrogenesis.
Best practice & research. Clinical gastroenterology 2011 Lee UE, Friedman SL -
Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1.
BMC molecular biology 2010 Garrido-Martin EM, Blanco FJ, Fernandez-L A, Langa C, Vary CP, Lee UE, Friedman SL, Botella LM, Bernabeu C -
Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene.
FEBS letters 2010 Lee UE, Ghiassi-Nejad Z, Paris AJ, Yea S, Narla G, Walsh M, Friedman SL