Tristan Courau, PhD
Specialist
Pathology
School of Medicine

Publications (20)

Top publication keywords:
NeoplasmsTransforming Growth Factor betaGene SilencingImmunotherapyNK Cell Lectin-Like Receptor Subfamily CT-Lymphocytes, RegulatoryImmune ToleranceTumor MicroenvironmentMefloquineColorectal NeoplasmsVascular Endothelial Growth Factor ASpheroids, CellularAntineoplastic Agents, ImmunologicalHistocompatibility Antigens Class ICyclonic Storms

• Cyclone: an accessible pipeline to analyze, evaluate, and optimize multiparametric cytometry data.
  Frontiers in immunology 2023 Patel RK, Jaszczak RG, Im K, Carey ND, Courau T, Bunis DG, Samad B, Avanesyan L, Chew NW, Stenske S, Jespersen JM, Publicover J, Edwards AW, Naser M, Rao AA, Lupin-Jimenez L, Krummel MF, Cooper S, …
• A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
  iScience 2023 Hackney JA, Shivram H, Vander Heiden J, Overall C, Orozco L, Gao X, Kim E, West N, Qamra A, Chang D, Chakrabarti A, Choy DF, Combes AJ, Courau T, Fragiadakis GK, Rao AA, Ray A, Tsui J, Hu K, Kuhn NF, …
• Transcriptional space-time mapping identifies concerted immune and stromal cell patterns and gene programs in wound healing and cancer.
  Cell stem cell 2023 Hu KH, Kuhn NF, Courau T, Tsui J, Samad B, Ha P, Kratz JR, Combes AJ, Krummel MF
• Cyclone: an accessible pipeline to analyze, evaluate and optimize multiparametric cytometry data.
  bioRxiv : the preprint server for biology 2023 Patel RK, Jaszczak RG, Kwok I, Carey ND, Courau T, Bunis D, Samad B, Avanesyan L, Chew NW, Stenske S, Jespersen JM, Publicover J, Edwards A, Naser M, Rao AA, Lupin-Jimenez L, Krummel MF, Cooper S, …
• Correction: Activated dendritic cells modulate proliferation and differentiation of human myoblasts.
  Cell death & disease 2022 Ladislau L, Portilho DM, Courau T, Solares-Pérez A, Negroni E, Lainé J, Klatzmann D, Bonomo A, Allenbach Y, Benveniste O, Riederer I, Savino W, Mouly V, Butler-Browne G, Benjamim CF

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• Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition.
  Gut 2022 Bonnereau J, Courau T, Asesio N, Salfati D, Bouhidel F, Corte H, Hamoudi S, Hammoudi N, Lavolé J, Vivier-Chicoteau J, Chardiny V, Maggiori L, Blery M, Remark R, Bonnafous C, Cattan P, Toubert A, Bhat …
• Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer.
  Cancer cell 2022 Kersten K, Hu KH, Combes AJ, Samad B, Harwin T, Ray A, Rao AA, Cai E, Marchuk K, Artichoker J, Courau T, Shi Q, Belk J, Satpathy AT, Krummel MF
• Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer.
  Cell reports 2022 Laviron M, Petit M, Weber-Delacroix E, Combes AJ, Arkal AR, Barthélémy S, Courau T, Hume DA, Combadière C, Krummel MF, Boissonnas A
• Discovering dominant tumor immune archetypes in a pan-cancer census.
  Cell 2021 Combes AJ, Samad B, Tsui J, Chew NW, Yan P, Reeder GC, Kushnoor D, Shen A, Davidson B, Barczak AJ, Adkisson M, Edwards A, Naser M, Barry KC, Courau T, Hammoudi T, Argüello RJ, Rao AA, Olshen AB, …
• Activating Immune Recognition in Pancreatic Ductal Adenocarcinoma via Autophagy Inhibition, MEK Blockade, and CD40 Agonism.
  Gastroenterology 2021 Jiang H, Courau T, Borison J, Ritchie AJ, Mayer AT, Krummel MF, Collisson EA
• Publisher Correction: Global absence and targeting of protective immune states in severe COVID-19.
  Nature 2021 Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, …
• Global absence and targeting of protective immune states in severe COVID-19.
  Nature 2021 Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, …
• KLRG1 and CD103 Expressions Define Distinct Intestinal Tissue-Resident Memory CD8 T Cell Subsets Modulated in Crohn's Disease.
  Frontiers in immunology 2020 Bottois H, Ngollo M, Hammoudi N, Courau T, Bonnereau J, Chardiny V, Grand C, Gergaud B, Allez M, Le Bourhis L
• Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment.
  Journal for immunotherapy of cancer 2019 Courau T, Bonnereau J, Chicoteau J, Bottois H, Remark R, Assante Miranda L, Toubert A, Blery M, Aparicio T, Allez M, Le Bourhis L
• Role of Chemokine Receptor CCR4 and Regulatory T Cells in Wound Healing of Diabetic Mice.
  The Journal of investigative dermatology 2018 Barros JF, Waclawiak I, Pecli C, Borges PA, Georgii JL, Ramos-Junior ES, Canetti C, Courau T, Klatzmann D, Kunkel SL, Penido C, Canto FB, Benjamim CF
• Activated dendritic cells modulate proliferation and differentiation of human myoblasts.
  Cell death & disease 2018 Ladislau L, Portilho DM, Courau T, Solares-Pérez A, Negroni E, Lainé J, Klatzmann D, Bonomo A, Allenbach Y, Benveniste O, Riederer I, Savino W, Mouly V, Butler-Browne G, Benjamim CF
• TGF-β and VEGF cooperatively control the immunotolerant tumor environment and the efficacy of cancer immunotherapies.
  JCI insight 2016 Courau T, Nehar-Belaid D, Florez L, Levacher B, Vazquez T, Brimaud F, Bellier B, Klatzmann D
• Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.
  Journal of immunology (Baltimore, Md. : 1950) 2015 Nehar-Belaid D, Courau T, Dérian N, Florez L, Ruocco MG, Klatzmann D
• Regulatory T-cell development and function are impaired in mice lacking membrane expression of full length intercellular adhesion molecule-1.
  Immunology 2015 Gottrand G, Courau T, Thomas-Vaslin V, Prevel N, Vazquez T, Ruocco MG, Lambrecht B, Bellier B, Colombo BM, Klatzmann D
• Self-specific memory regulatory T cells protect embryos at implantation in mice.
  Journal of immunology (Baltimore, Md. : 1950) 2013 Chen T, Darrasse-Jèze G, Bergot AS, Courau T, Churlaud G, Valdivia K, Strominger JL, Ruocco MG, Chaouat G, Klatzmann D