Travis Zack, MD, PhD
Clinical Fellow
Medicine
School of Medicine

Publications (26)

Top publication keywords:
Natural Language ProcessingLabor, ObstetricHealth FacilitiesGliomaProtein Phosphatase 2COncogenesArtificial IntelligenceNeoplasmsEducation, MedicalGenomicsResearch PersonnelDNA Copy Number VariationsThrombocytopeniaClinical Decision-MakingGene Dosage

• Predictive Modeling of Drug-Related Adverse Events with Real-World Data: A Case Study of Linezolid Hematologic Outcomes.
  Clinical pharmacology and therapeutics 2024 Patel A, Doernberg SB, Zack T, Butte AJ, Radtke KK
• A comparative study of zero-shot inference with large language models and supervised modeling in breast cancer pathology classification.
  Research square 2024 Sushil M, Zack T, Mandair D, Zheng Z, Wali A, Yu YN, Quan Y, Butte AJ
• Introducing a Comprehensive Score of Systemic Anticancer Treatment Relevance.
  Studies in health technology and informatics 2024 Zack T, Warner JL
• Topic modeling on clinical social work notes for exploring social determinants of health factors.
  JAMIA open 2024 Sun S, Zack T, Williams CYK, Sushil M, Butte AJ
• Assessing the potential of GPT-4 to perpetuate racial and gender biases in health care: a model evaluation study.
  The Lancet. Digital health 2024 Zack T, Lehman E, Suzgun M, Rodriguez JA, Celi LA, Gichoya J, Jurafsky D, Szolovits P, Bates DW, Abdulnour RE, Butte AJ, Alsentzer E

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• Defining incidence and complications of fibrolamellar liver cancer through tiered computational analysis of clinical data.
  NPJ precision oncology 2023 Zack T, Losert KP, Maisel SM, Wild J, Yaqubie A, Herman M, Knox JJ, Mayer RJ, Venook AP, Butte A, O'Neill AF, Abou-Alfa GK, Gordan JD
• A Clinical Reasoning-Encoded Case Library Developed through Natural Language Processing.
  Journal of general internal medicine 2022 Zack T, Dhaliwal G, Geha R, Margaretten M, Murray S, Hong JC
• Structural variants shape driver combinations and outcomes in pediatric high-grade glioma.
  Nature cancer 2022 Dubois FPB, Shapira O, Greenwald NF, Zack T, Wala J, Tsai JW, Crane A, Baguette A, Hadjadj D, Harutyunyan AS, Kumar KH, Blattner-Johnson M, Vogelzang J, Sousa C, Kang KS, Sinai C, Wang DK, Khadka P, …
• PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.
  Nature communications 2022 Khadka P, Reitman ZJ, Lu S, Buchan G, Gionet G, Dubois F, Carvalho DM, Shih J, Zhang S, Greenwald NF, Zack T, Shapira O, Pelton K, Hartley R, Bear H, Georgis Y, Jarmale S, Melanson R, Bonanno K, …
• CovidCounties is an interactive real time tracker of the COVID19 pandemic at the level of US counties.
  Scientific data 2020 Arneson D, Elliott M, Mosenia A, Oskotsky B, Solodar S, Vashisht R, Zack T, Bleicher P, Butte AJ, Rudrapatna VA
• CovidCounties - an interactive, real-time tracker of the COVID-19 pandemic at the level of US counties.
  medRxiv : the preprint server for health sciences 2020 Arneson D, Elliott M, Mosenia A, Oskotsky B, Vashisht R, Zack T, Bleicher P, Butte AJ, Rudrapatna VA
• Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.
  eLife 2017 Paolella BR, Gibson WJ, Urbanski LM, Alberta JA, Zack TI, Bandopadhayay P, Nichols CA, Agarwalla PK, Brown MS, Lamothe R, Yu Y, Choi PS, Obeng EA, Heckl D, Wei G, Wang B, Tsherniak A, Vazquez F, Weir …
• Genomic evolution and chemoresistance in germ-cell tumours.
  Nature 2016 Taylor-Weiner A, Zack T, O'Donnell E, Guerriero JL, Bernard B, Reddy A, Han GC, AlDubayan S, Amin-Mansour A, Schumacher SE, Litchfield K, Turnbull C, Gabriel S, Beroukhim R, Getz G, Carter SL, Hirsch …
• Genomic Heterogeneity and Exceptional Response to Dual Pathway Inhibition in Anaplastic Thyroid Cancer.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Gibson WJ, Ruan DT, Paulson VA, Barletta JA, Hanna GJ, Kraft S, Calles A, Nehs MA, Moore FD, Taylor-Weiner A, Wala JA, Zack TI, Lee TC, Fennessy FM, Alexander EK, Thomas T, Janne PA, Garraway LA, …
• The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis.
  Nature genetics 2016 Gibson WJ, Hoivik EA, Halle MK, Taylor-Weiner A, Cherniack AD, Berg A, Holst F, Zack TI, Werner HM, Staby KM, Rosenberg M, Stefansson IM, Kusonmano K, Chevalier A, Mauland KK, Trovik J, Krakstad C, …
• Characterizing genomic alterations in cancer by complementary functional associations.
  Nature biotechnology 2016 Kim JW, Botvinnik OB, Abudayyeh O, Birger C, Rosenbluh J, Shrestha Y, Abazeed ME, Hammerman PS, DiCara D, Konieczkowski DJ, Johannessen CM, Liberzon A, Alizad-Rahvar AR, Alexe G, Aguirre A, Ghandi M, …
• Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
  The New England journal of medicine 2015 Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, …
• Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.
  Genes & development 2014 Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, Beroukhim R, Marto JA, Vidal M, Gaudet S, Hill DE, …
• Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins.
  Nature genetics 2014 Gong Y, Zack TI, Morris LG, Lin K, Hukkelhoven E, Raheja R, Tan IL, Turcan S, Veeriah S, Meng S, Viale A, Schumacher SE, Palmedo P, Beroukhim R, Chan TA
• Pan-cancer patterns of somatic copy number alteration.
  Nature genetics 2013 Zack TI, Schumacher SE, Carter SL, Cherniack AD, Saksena G, Tabak B, Lawrence MS, Zhsng CZ, Wala J, Mermel CH, Sougnez C, Gabriel SB, Hernandez B, Shen H, Laird PW, Getz G, Meyerson M, Beroukhim R
• Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers.
  PloS one 2013 Raeder MB, Birkeland E, Trovik J, Krakstad C, Shehata S, Schumacher S, Zack TI, Krohn A, Werner HM, Moody SE, Wik E, Stefansson IM, Holst F, Oyan AM, Tamayo P, Mesirov JP, Kalland KH, Akslen LA, Simon…
• Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif.
  Nature communications 2013 Hamilton MP, Rajapakshe K, Hartig SM, Reva B, McLellan MD, Kandoth C, Ding L, Zack TI, Gunaratne PH, Wheeler DA, Coarfa C, McGuire SE
• ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens.
  Genome research 2012 Shao DD, Tsherniak A, Gopal S, Weir BA, Tamayo P, Stransky N, Schumacher SE, Zack TI, Beroukhim R, Garraway LA, Margolin AA, Root DE, Hahn WC, Mesirov JP
• β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
  Cell 2012 Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, …
• Cancer vulnerabilities unveiled by genomic loss.
  Cell 2012 Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn …
• Absolute quantification of somatic DNA alterations in human cancer.
  Nature biotechnology 2012 Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, Getz G