Tommaso Di Ianni, PhD
Assistant Professor
Psychiatry
School of Medicine

Tommaso Di Ianni is an Assistant Professor in the Departments of Psychiatry & Behavioral Sciences and Radiology & Biomedical Imaging. He is the Director of the UCSF Basic Ultrasound Research Program and co-Director of the UCSF Focused Ultrasound in Neuroscience Program. His lab develops ultrasound-based innovations for image-guided treatment of neuropsychiatric disorders. Check our lab website for further information: https://diiannilab.org/.

Awards

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• Stephen I. Katz Early Stage Investigator Research Project Grant, NIH, 2025
• PARC Fellowship, UCSF Pain and Addiction Research Center, 2024
• Dean’s Postdoctoral Fellowship, Stanford University School of Medicine, 2019
• New Investigator Award for Basic Science, American Institute of Ultrasound in Medicine, 2017

Education & Training

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• Postdoc Radiology Stanford University 2023
• MS Electronic Engineering University of Bologna 2014
• BS Electronic Engineering University of Bologna 2011
• PhD Biomedical Engineering Technical University of Denmark 2107

Websites

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• Di Ianni Lab (diiannilab.org)

Grants and Projects

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• Dissecting the circuit-level mechanisms of ultrasound neuromodulation, NIH, 2025-2029
• Precise ultrasound neuromodulation in essential tremor, Focused Ultrasound Foundation, 2024-2026
• Minimally invasive closed-loop neuromodulation via combined focused ultrasound and functional ultrasound imaging, UCSF Weill Institute for Neurosciences and Catalyst Program, 2024-2025

Publications (14)

Top publication keywords:
UltrasonographyWireless TechnologyReceptors, OpioidDrug Delivery SystemsExcitatory Amino Acid AntagonistsUltrasonic WavesWakefulnessKetamineBlood Flow VelocityNanoparticlesSex CharacteristicsRNA, AntisenseNerve NetData CompressionPrefrontal Cortex

• Ketamine-induced static and dynamic functional connectivity changes are modulated by opioid receptors and biological sex in rats.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2025 Grasso V, Tennyson J, Airan RD, Di Ianni T
• Thalamic transcranial ultrasound stimulation in treatment resistant depression.
  Brain stimulation 2024 Fan JM, Woodworth K, Murphy KR, Hinkley L, Cohen JL, Yoshimura J, Choi I, Tremblay-McGaw AG, Mergenthaler J, Good CH, Pellionisz PA, Lee AM, Di Ianni T, Sugrue LP, Krystal AD
• Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology.
  Neuron 2024 Murphy KR, Farrell JS, Bendig J, Mitra A, Luff C, Stelzer IA, Yamaguchi H, Angelakos CC, Choi M, Bian W, DiIanni T, Pujol EM, Matosevich N, Airan R, Gaudillière B, Konofagou EE, Butts-Pauly K, Soltesz…
• Sex dependence of opioid-mediated responses to subanesthetic ketamine in rats.
  Nature communications 2024 Di Ianni T, Ewbank SN, Levinstein MR, Azadian MM, Budinich RC, Michaelides M, Airan RD
• High-throughput ultrasound neuromodulation in awake and freely behaving rats.
  Brain stimulation 2023 Di Ianni T, Morrison KP, Yu B, Murphy KR, de Lecea L, Airan RD

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• Mu Opioid Receptor Activation Mediates (S)-ketamine Reinforcement in Rats: Implications for Abuse Liability.
  Biological psychiatry 2022 Levinstein MR, Carlton ML, Di Ianni T, Ventriglia EN, Rizzo A, Gomez JL, Budinich RC, Shaham Y, Airan RD, Zarate CA, Bonaventura J, Michaelides M
• Deep-fUS: A Deep Learning Platform for Functional Ultrasound Imaging of the Brain Using Sparse Data.
  IEEE transactions on medical imaging 2022 Di Ianni T, Airan RD
• Focused Ultrasound for Noninvasive, Focal Pharmacologic Neurointervention.
  Frontiers in neuroscience 2020 Wang JB, Di Ianni T, Vyas DB, Huang Z, Park S, Hosseini-Nassab N, Aryal M, Airan RD
• Ultrasound/microbubble-mediated targeted delivery of anticancer microRNA-loaded nanoparticles to deep tissues in pigs.
  Journal of controlled release : official journal of the Controlled Release Society 2019 Di Ianni T, Bose RJC, Sukumar UK, Bachawal S, Wang H, Telichko A, Herickhoff C, Robinson E, Baker S, Vilches-Moure JG, Felt SA, Gambhir SS, Paulmurugan R, Dahl JD
• Portable Vector Flow Imaging Compared With Spectral Doppler Ultrasonography.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 2018 Di Ianni T, Hansen KL, Villagomez Hoyos CA, Moshavegh R, Nielsen MB, Jensen JA
• A Vector Flow Imaging Method for Portable Ultrasound Using Synthetic Aperture Sequential Beamforming.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 2017 Di Ianni T, Villagomez Hoyos CA, Ewertsen C, Kjeldsen TK, Mosegaard J, Nielsen MB, Jensen JA
• System-Level Design of an Integrated Receiver Front End for a Wireless Ultrasound Probe.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 2016 Di Ianni T, Hemmsen MC, Llimos Muntal P, Jorgensen IH, Jensen JA
• Compressive sensing of full wave field data for structural health monitoring applications.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 2015 Di Ianni T, De Marchi L, Perelli A, Marzani A
• Model-based compressive sensing for damage localization in Lamb wave inspection.
  IEEE transactions on ultrasonics, ferroelectrics, and frequency control 2013 Perelli A, Di Ianni T, Marzani A, De Marchi L, Masetti G