Tomas Wald, PhD
Specialist
Orofacial Sciences
School of Dentistry

Publications (19)

Top publication keywords:
PotassiumAdenylate Cyclase ToxinMass SpectrometryDental Enamel ProteinsBacterial ToxinsMacrophage-1 AntigenCricetulusExonsDental EnamelCD18 AntigensBordetella pertussisAmino Acid MotifsIntrinsically Disordered ProteinsOrganoidsCD11b Antigen

• Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis.
  The Journal of clinical investigation 2023 Reyes EA, Castillo-Azofeifa D, Rispal J, Wald T, Zwick RK, Palikuqi B, Mujukian A, Rabizadeh S, Gupta AR, Gardner JM, Boffelli D, Gartner ZJ, Klein OD
• A Suite of Mouse Reagents for Studying Amelogenesis.
  bioRxiv : the preprint server for biology 2023 Wald T, Verma A, Cooley V, Marangoni P, Cazares O, Sharir A, Sandoval EJ, Sung D, Najibi H, Drennon TY, Bush JO, Joester D, Klein OD
• Early evolution of enamel matrix proteins is reflected by pleiotropy of physiological functions.
  Scientific reports 2023 Spoutil F, Aranaz-Novaliches G, Prochazkova M, Wald T, Novosadova V, Kasparek P, Osicka R, Reseland JE, Lyngstadaas SP, Tiainen H, Bousova K, Vondrasek J, Sedlacek R, Prochazka J
• A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling.
  Cell stem cell 2023 Castillo-Azofeifa D, Wald T, Reyes EA, Gallagher A, Schanin J, Vlachos S, Lamarche-Vane N, Bomidi C, Blutt S, Estes MK, Nystul T, Klein OD
• SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal.
  Developmental cell 2022 Yu T, Cazares O, Tang AD, Kim HY, Wald T, Verma A, Liu Q, Barcellos-Hoff MH, Floor SN, Jung HS, Brooks AN, Klein OD

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• Inflation-collapse dynamics drive patterning and morphogenesis in intestinal organoids.
  Cell stem cell 2021 Tallapragada NP, Cambra HM, Wald T, Keough Jalbert S, Abraham DM, Klein OD, Klein AM
• Generation of Knockout Gene-Edited Human Intestinal Organoids.
  Methods in molecular biology (Clifton, N.J.) 2020 Rajendra C, Wald T, Barber K, Spence JR, Fattahi F, Klein OD
• A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.
  Nature cell biology 2019 Sharir A, Marangoni P, Zilionis R, Wan M, Wald T, Hu JK, Kawaguchi K, Castillo-Azofeifa D, Epstein L, Harrington K, Pagella P, Mitsiadis T, Siebel CW, Klein AM, Klein OD
• Atoh1+ secretory progenitors possess renewal capacity independent of Lgr5+ cells during colonic regeneration.
  The EMBO journal 2019 Castillo-Azofeifa D, Fazio EN, Nattiv R, Good HJ, Wald T, Pest MA, de Sauvage FJ, Klein OD, Asfaha S
• Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding.
  Emerging microbes & infections 2018 Osickova A, Balashova N, Masin J, Sulc M, Roderova J, Wald T, Brown AC, Koufos E, Chang EH, Giannakakis A, Lally ET, Osicka R
• Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif.
  Proceedings of the National Academy of Sciences of the United States of America 2017 Wald T, Spoutil F, Osickova A, Prochazkova M, Benada O, Kasparek P, Bumba L, Klein OD, Sedlacek R, Sebo P, Prochazka J, Osicka R
• Enamel evolution: Back in time by a molecular manipulation.
  European Microscopy Congress 2016: Proceedings 2016 Tomas Wald, Frantisek Spoutil, Adriana Osickova, Michaela Prochazkova, Oldrich Benada, Petr Kasparek, Ladislav Bumba, Ophir Klein, Radislav Sedlacek, Peter Sebo, Jan Prochazka, Radim Osicka
• Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.
  Molecular cell 2016 Bumba L, Masin J, Macek P, Wald T, Motlova L, Bibova I, Klimova N, Bednarova L, Veverka V, Kachala M, Svergun DI, Barinka C, Sebo P
• Transmembrane segments of complement receptor 3 do not participate in cytotoxic activities but determine receptor structure required for action of Bordetella adenylate cyclase toxin.
  Pathogens and disease 2016 Wald T, Osickova A, Masin J, Liskova PM, Petry-Podgorska I, Matousek T, Sebo P, Osicka R
• The Bordetella pertussis Type III Secretion System Tip Complex Protein Bsp22 Is Not a Protective Antigen and Fails To Elicit Serum Antibody Responses during Infection of Humans and Mice.
  Infection and Immunity 2014 Rodrigo Villarino Romero, Ilona Bibova, Ondrej Cerny, Branislav Vecerek, Tomas Wald, Oldrich Benada, Jana Zavadilova, Radim Osicka, Peter Sebo
• Quantification of potassium levels in cells treated with Bordetella adenylate cyclase toxin.
  Analytical biochemistry 2014 Wald T, Petry-Podgorska I, Fiser R, Matousek T, Dedina J, Osicka R, Sebo P, Masin J
• Intrinsically disordered enamel matrix protein ameloblastin forms ribbon-like supramolecular structures via an N-terminal segment encoded by exon 5.
  The Journal of biological chemistry 2013 Wald T, Osickova A, Sulc M, Benada O, Semeradtova A, Rezabkova L, Veverka V, Bednarova L, Maly J, Macek P, Sebo P, Slaby I, Vondrasek J, Osicka R
• The Bordetella pertussis type III secretion system tip complex protein Bsp22 is not a protective antigen and fails to elicit serum antibody responses during infection of humans and mice.
  Infection and immunity 2013 Villarino Romero R, Bibova I, Cerny O, Vecerek B, Wald T, Benada O, Zavadilova J, Osicka R, Sebo P
• Biophysical characterization of recombinant human ameloblastin.
  European journal of oral sciences 2011 Wald T, Bednárová L, Osicka R, Pachl P, Sulc M, Lyngstadaas SP, Slaby I, Vondrášek J