Tina Bhutani-Jacques, MD
Associate Professor
Dermatology
School of Medicine

My clinical expertise includes the treatment of complex, treatment resistant cases of inflammatory skin diseases using unique combinations of topical agents, systemic treatments, biologics, and phototherapy. I also direct the Dermatology Clinical Research Unit where I utilize my advanced training in clinical research methods to oversee numerous sponsored and investigator-initiated clinical studies and supervise a research team consisting of a post-doctoral research fellow, 3 clinical research coordinators, and 3 medical students. I am currently the PI for 6 clinical trials developing new therapeutics or diagnostics for psoriasis, atopic dermatitis, and alopecia areata.

My research thus far has focused on assessing and improving quality of life and mental health in patients with psoriasis by treating their skin disease effectively. I now would like to expand upon this focus and look for methods to decrease the stress burden of psoriasis and improve patient well-being in the hopes of improving quality of life in a new and unique way. Nutrition, exercise, sleep, social connectedness, and mindfulness are the five pillars known to increase overall wellness in both healthy and diseased patients. Over my career, I hope to look further into each of these aspects and their importance in inflammatory skin disease, starting with a research program focusing on sleep in psoriasis and its impact on disease severity, mental health and cardiometabolic comorbidities.

• The role of gender, race, and ethnicity in psoriasis patients with COVID-19 infection: A cross-sectional study.
  International journal of women's dermatology 2022 Nguyen C, Shwe S, Yale K, Ghigi A, Zheng K, Mesinkovska NA, Bhutani T
• Demographic and Clinical Factors Associated with Patient-Reported Remission in Psoriasis.
  Dermatology and therapy 2022 Gondo G, Hadeler E, Brownstone N, Maverakis E, Merola JF, Armstrong AW, Bhutani T, Bell SJ, Liao W
• Combined Single Cell Transcriptome and Surface Epitope Profiling Identifies Potential Biomarkers of Psoriatic Arthritis and Facilitates Diagnosis via Machine Learning.
  Frontiers in immunology 2022 Liu J, Kumar S, Hong J, Huang ZM, Paez D, Castillo M, Calvo M, Chang HW, Cummins DD, Chung M, Yeroushalmi S, Bartholomew E, Hakimi M, Ye CJ, Bhutani T, Matloubian M, Gensler LS, Liao W
• Evaluation of a Case Series of Patients With Generalized Pustular Psoriasis in the United States.
  JAMA dermatology 2022 Noe MH, Wan MT, Mostaghimi A, Gelfand JM, Pustular Psoriasis in the US Research Group, Agnihothri R, Armstrong AW, Bhutani T, Bridges A, Brownstone N, Butt M, Duffin KPC, Carr C, Creadore A, DeNiro KL…
• Evaluation of a Case Series of Patients With Palmoplantar Pustulosis in the United States.
  JAMA dermatology 2022 Noe MH, Wan MT, Mostaghimi A, Gelfand JM, Pustular Psoriasis in the US Research Group, Agnihothri R, Armstrong AW, Bhutani T, Bridges A, Brownstone N, Butt M, Duffin KPC, Carr C, Creadore A, DeNiro KL…
• The Role of IL-17 Cytokines in Psoriasis.
  ImmunoTargets and therapy 2021 Mosca M, Hong J, Hadeler E, Hakimi M, Liao W, Bhutani T
• Off-label uses of TNF-a inhibitors and IL-12/23 inhibitors in dermatology.
  Dermatology online journal 2021 Hong JJ, Hadeler EK, Mosca ML, Brownstone ND, Bhutani T, Liao WJ
• Innovations in translational research in dermatology: minimally invasive methods for biosample acquisition.
  Dermatology online journal 2021 Hadeler E, Mosca M, Hong J, Brownstone N, Liao W, Bhutani T
• A cross-sectional study of ethnoracial representation in pediatric plaque psoriasis clinical trials.
  Journal of the American Academy of Dermatology 2021 Mosca M, Hong J, Hadeler E, Hakimi M, Brownstone N, Bhutani T, Liao W
• Cultural and biological factors in body dysmorphic disorder in East Asia.
  Dermatology online journal 2021 Hong J, Hadeler E, Mosca M, Brownstone N, Bhutani T, Koo J
• Psoriasis and Cardiometabolic Comorbidities: An Evaluation of the Impact of Systemic Treatments in Randomized Clinical Trials.
  Dermatology and therapy 2021 Mosca M, Hong J, Hadeler E, Hakimi M, Brownstone N, Liao W, Bhutani T
• Perspectives on the Future Development of Mobile Applications for Dermatology Clinical Research.
  Dermatology and therapy 2021 Hadeler E, Hong J, Mosca M, Hakimi M, Brownstone N, Bhutani T, Liao W
• Atypical Presentation of Pityriasis Rubra Pilaris: Challenges in Diagnosis and Management.
  Cutis 2021 Abrouk M, Nakamura M, Zhu TH, Farahnik B, Koo J, Bhutani T
• Racial disparities in clinical trials of biologic treatments for psoriatic arthritis.
  Journal of the American Academy of Dermatology 2021 Shwe S, Nguyen C, Bhutani T
• Dupilumab-Induced Facial Flushing After Alcohol Consumption.
  Cutis 2021 Brownstone ND, Reddy V, Thibodeaux Q, Myers B, Chan S, Liao W, Bhutani T
• Seeing the Treatment of Psoriasis in a New Light: A Novel Medical Device Utilizing Localized Coal Tar and Narrowband UVB for Targeted Treatment of Plaque Psoriasis.
  Journal of drugs in dermatology : JDD 2021 Brownstone ND, Bridges A, Bhutani T, Anderson E, Sugarman J
• Nail Psoriasis: A Review of Effective Therapies and Recommendations for Management.
  Dermatology and therapy 2021 Hadeler E, Mosca M, Hong J, Brownstone N, Bhutani T, Liao W
• Genital and Inverse/Intertriginous Psoriasis: An Updated Review of Therapies and Recommendations for Practical Management.
  Dermatology and therapy 2021 Hong JJ, Mosca ML, Hadeler EK, Brownstone ND, Bhutani T, Liao WJ
• Scalp Psoriasis: A Literature Review of Effective Therapies and Updated Recommendations for Practical Management.
  Dermatology and therapy 2021 Mosca M, Hong J, Hadeler E, Brownstone N, Bhutani T, Liao W
• Biologic Treatments of Psoriasis: An Update for the Clinician.
  Biologics : targets & therapy 2021 Brownstone ND, Hong J, Mosca M, Hadeler E, Liao W, Bhutani T, Koo J
• A common treatment for a rare condition: Narrowband-Ultraviolet B (NB-UVB) phototherapy for the treatment of a recalcitrant acquired port wine stain.
  Photodermatology, photoimmunology & photomedicine 2021 Brownstone N, Bhutani T
• Prescribing Isotretinoin for Transgender Patients: A Call to Action and Recommendations.
  Journal of drugs in dermatology : JDD 2021 Sanchez DP, Brownstone N, Thibodeaux Q, Reddy V, Myers B, Chan S, Bhutani T
• Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer.
  The Journal of allergy and clinical immunology 2020 Liu J, Chang HW, Huang ZM, Nakamura M, Sekhon S, Ahn R, Munoz-Sandoval P, Bhattarai S, Beck KM, Sanchez IM, Yang E, Pauli M, Arron ST, Fung-Leung WP, Munoz E, Liu X, Bhutani T, North J, Fourie AM, …
• Therapies for Psoriasis: Clinical and Economic Comparisons.
  Journal of drugs in dermatology : JDD 2020 Marchetti A, Bhutani T, Lockshin B, Siegel DM, Behringer F
• Sleep, Immunological Memory, and Inflammatory Skin Disease.
  Dermatology (Basel, Switzerland) 2020 Myers B, Reddy V, Chan S, Thibodeaux Q, Brownstone N, Bhutani T
• Impact of Halobetasol Propionate and Tazarotene Lotion 0.01%/0.045% in the Management of Plaque Psoriasis in Adults.
  Clinical, cosmetic and investigational dermatology 2020 Reddy V, Myers B, Yang EJ, Bhutani T
• Novel Coronavirus Disease (COVID-19) and Biologic Therapy for Psoriasis: Successful Recovery in Two Patients After Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
  Dermatology and therapy 2020 Brownstone ND, Thibodeaux QG, Reddy VD, Myers BA, Chan SY, Bhutani T, Liao W
• The gut microbiome in psoriasis and psoriatic arthritis.
  Best practice & research. Clinical rheumatology 2020 Myers B, Brownstone N, Reddy V, Chan S, Thibodeaux Q, Truong A, Bhutani T, Chang HW, Liao W
• Lymphomatoid papulosis successfully managed with excimer laser maintenance therapy.
  JAAD case reports 2020 Reddy V, Thibodeaux Q, Bhutani T, Sugarman JL
• Novel Coronavirus Disease (COVID-19) and Biologic Therapy in Psoriasis: Infection Risk and Patient Counseling in Uncertain Times.
  Dermatology and therapy 2020 Brownstone ND, Thibodeaux QG, Reddy VD, Myers BA, Chan SY, Bhutani T, Liao W
• Treatment of Plaque Psoriasis With an Excimer Laser Utilizing an Optimal Therapeutic UVB Dose Protocol.
  Journal of drugs in dermatology : JDD 2020 Thibodeaux Q, Beck K, Lockshin BN, Bhatia N, Levin E, Koo J, Bhutani T
• Psoriasis Vulgaris Successfully Treated with Goeckerman Treatment at Home: A Patient and Physician's Experience.
  Dermatology and therapy 2020 Reddy V, Thomas S, Thibodeaux Q, Myers B, Bhutani T, Liao W
• Evaluation of a Genetic Risk Score for Diagnosis of Psoriatic Arthritis.
  Journal of psoriasis and psoriatic arthritis 2020 Smith MP, Ly K, Thibodeaux Q, Beck K, Yang E, Sanchez I, Nititham J, Bhutani T, Liao W
• Implementation of an Ultraviolet Phototherapy Service at a National Referral Hospital in Western Kenya: Reflections on Challenges and Lessons Learned.
  Dermatology and therapy 2019 Ly K, Chang AY, Kiprono SK, Jose M, Smith MP, Beck K, Sekhon S, Muraguri I, Mungai M, Coates SJ, Thibodeaux Q, Hulse S, Gualberto M, Jeon C, Nakamura M, Bhutani T, Maurer T, Liao W
• Progressive Hyperpigmented Plaques: Answer.
  The American Journal of dermatopathology 2019 Beck KM, North JP, Bhutani T
• Progressive Hyperpigmented Plaques: Challenge.
  The American Journal of dermatopathology 2019 Beck KM, North JP, Bhutani T
• Beyond the Booth: Excimer Laser for Cutaneous Conditions.
  Dermatologic clinics 2019 Ly K, Smith MP, Thibodeaux QG, Beck KM, Liao W, Bhutani T
• Anti IL-17 in psoriasis.
  Expert review of clinical immunology 2019 Ly K, Smith MP, Thibodeaux Q, Reddy V, Liao W, Bhutani T
• Palmoplantar Pustulosis in Electronic Cigarette Users: A Potential for Concern.
  Dermatology (Basel, Switzerland) 2019 Reddy V, Bhutani T
• Chronic erythema nodosum with koebnerization to plaque psoriasis.
  International journal of women's dermatology 2019 Smith MP, Ly K, Thibodeaux Q, Bhutani T
• Acrodermatitis continua of Hallopeau: clinical perspectives.
  Psoriasis (Auckland, N.Z.) 2019 Smith MP, Ly K, Thibodeaux Q, Bhutani T, Liao W, Beck KM
• Dupilumab for the treatment of severe photodermatitis.
  JAAD case reports 2019 Smith MP, Ly K, Thibodeaux Q, Beck K, Berger T, Khodosh R, Liao W, Bhutani T
• Dupilumab in patients with chronic hepatitis B on concomitant entecavir.
  JAAD case reports 2019 Ly K, Smith MP, Thibodeaux Q, Beck K, Bhutani T, Liao W
• Emerging Methods to Objectively Assess Pruritus in Atopic Dermatitis.
  Dermatology and therapy 2019 Smith MP, Ly K, Thibodeaux Q, Weerasinghe T, Wu JJ, Yosipovitch G, Bhutani T, Liao W
• Home phototherapy for patients with vitiligo: challenges and solutions.
  Clinical, cosmetic and investigational dermatology 2019 Smith MP, Ly K, Thibodeaux Q, Bhutani T, Nakamura M
• Diagnosis and screening of patients with generalized pustular psoriasis.
  Psoriasis (Auckland, N.Z.) 2019 Ly K, Beck KM, Smith MP, Thibodeaux Q, Bhutani T
• Evaluating guselkumab: an anti-IL-23 antibody for the treatment of plaque psoriasis.
  Drug design, development and therapy 2019 Yang EJ, Smith MP, Ly K, Bhutani T
• Factors Influencing Sleep Difficulty and Sleep Quantity in the Citizen Pscientist Psoriatic Cohort.
  Dermatology and therapy 2019 Smith MP, Ly K, Thibodeaux Q, Weerasinghe T, Beck K, Shankle L, Armstrong AW, Boas M, Bridges A, Doris F, Gelfand JM, Lafoy B, Orbai AM, Takeshita J, Truman S, Wan MT, Wu JJ, Siegel MP, Bell SJ, …
• A review of dupilumab in the treatment of atopic diseases.
  Human vaccines & immunotherapeutics 2019 Thibodeaux Q, Smith MP, Ly K, Beck K, Liao W, Bhutani T
• Dupilumab Treatment for Generalized Prurigo Nodularis.
  JAMA dermatology 2019 Beck KM, Yang EJ, Sekhon S, Bhutani T, Liao W
• The impact of pediatric atopic dermatitis on families: A review.
  Pediatric dermatology 2018 Yang EJ, Beck KM, Sekhon S, Bhutani T, Koo J
• A20 and ABIN1 Suppression of a Keratinocyte Inflammatory Program with a Shared Single-Cell Expression Signature in Diverse Human Rashes.
  The Journal of investigative dermatology 2018 Harirchian P, Lee J, Hilz S, Sedgewick AJ, Perez White BE, Kesling MJ, Mully T, Golovato J, Gray M, Mauro TM, Purdom E, Kim EA, Sbitany H, Bhutani T, Vaske CJ, Benz SC, Cho RJ, Cheng JB
• Pharmacy costs of systemic medications for hidradenitis suppurativa in the United States.
  The Journal of dermatological treatment 2018 Yang EJ, Beck KM, Bhutani T, Feldman SR, Shi VY
• Psoriasis risk factors and triggers.
  Cutis 2018 Lee EB, Wu KK, Lee MP, Bhutani T, Wu JJ
• Recent Developments in Atopic Dermatitis.
  Pediatrics 2018 Yang EJ, Sekhon S, Sanchez IM, Beck KM, Bhutani T
• Review of European registries for psoriasis.
  The Journal of dermatological treatment 2018 Amin M, Lee EB, Bhutani T, Wu JJ
• Pharmacy costs of specialty medications for plaque psoriasis in the United States.
  Journal of the American Academy of Dermatology 2018 Yang EJ, Beck KM, Sekhon S, Bhutani T
• Guselkumab for the treatment of moderate-to-severe plaque psoriasis.
  Expert review of clinical pharmacology 2018 Yang EJ, Sanchez IM, Beck K, Sekhon S, Wu JJ, Bhutani T
• Do psoriasis patients engage in vigorous physical activity?
  Cutis 2018 Amin M, Lee EB, Bhutani T, Wu JJ
• Emerging therapies in psoriasis: a systematic review.
  Cutis 2018 Lee EB, Amin M, Bhutani T, Wu JJ
• Neuromodulation in Inflammatory Skin Disease.
  Dermatology and therapy 2018 Yang EJ, Sekhon S, Beck KM, Bhutani T, Koo J
• Psoriasis treatment in HIV-positive patients: a systematic review of systemic immunosuppressive therapies.
  Cutis 2018 Nakamura M, Abrouk M, Farahnik B, Zhu TH, Bhutani T
• A systematic review of active comparator controlled clinical trials in patients with moderate-to-severe psoriasis.
  The Journal of dermatological treatment 2017 No DJ, Amin M, Bhutani T, Wu JJ
• Clinical utility of ixekizumab in the treatment of moderate-to-severe plaque psoriasis.
  Psoriasis (Auckland, N.Z.) 2017 Sekhon S, Jeon C, Nakamura M, Yan D, Afifi L, Bhutani T, Levin E
• Review of IL-17 inhibitors for psoriasis.
  The Journal of dermatological treatment 2017 Amin M, Darji K, No DJ, Bhutani T, Wu JJ
• Generalized pustular psoriasis treated with apremilast in a patient with multiple medical comorbidities.
  JAAD case reports 2017 Jeon C, Nakamura M, Sekhon S, Yan D, Wu JJ, Liao W, Bhutani T
• Monoclonal antibodies inhibiting IL-12, -23, and -17 for the treatment of psoriasis.
  Human vaccines & immunotherapeutics 2017 Jeon C, Sekhon S, Yan D, Afifi L, Nakamura M, Bhutani T
• Review of the mechanism of action of coal tar in psoriasis.
  The Journal of dermatological treatment 2017 Sekhon S, Jeon C, Nakamura M, Afifi L, Yan D, Wu JJ, Liao W, Bhutani T
• Risk of cutaneous squamous cell carcinoma after treatment of basal cell carcinoma with vismodegib.
  Journal of the American Academy of Dermatology 2017 Bhutani T, Abrouk M, Sima CS, Sadetsky N, Hou J, Caro I, Chren MM, Arron ST
• Frequency and Management of Sleep Disturbance in Adults with Atopic Dermatitis: A Systematic Review.
  Dermatology and therapy 2017 Jeon C, Yan D, Nakamura M, Sekhon S, Bhutani T, Berger T, Liao W
• Apremilast treatment of atopic dermatitis and other chronic eczematous dermatoses.
  Journal of the American Academy of Dermatology 2017 Abrouk M, Farahnik B, Zhu TH, Nakamura M, Singh R, Lee K, Lucking SM, Blossom J, Liao W, Koo J, Bhutani T, Shinkai K, Nguyen T
• Update on the Systemic Risks of Superpotent Topical Steroids.
  Journal of drugs in dermatology : JDD 2017 Nakamura M, Abrouk M, Zhu H, Farahnik B, Koo J, Bhutani T
• Guselkumab for the Treatment of Psoriasis: A Review of Phase III Trials.
  Dermatology and therapy 2017 Nakamura M, Lee K, Jeon C, Sekhon S, Afifi L, Yan D, Lee K, Bhutani T
• Beyond monotherapy: a systematic review on creative strategies in topical therapy of psoriasis.
  The Journal of dermatological treatment 2017 Koo K, Jeon C, Bhutani T
• Use of an oral phosphodiesterase-4 inhibitor (apremilast) for the treatment of chronic, severe atopic dermatitis: a case report.
  Dermatology online journal 2017 Farahnik B, Beroukhim K, Nakamura M, Abrouk M, Zhu TH, Singh R, Lee K, Bhutani T, Koo J, Liao W
• Influence of diet on the gut microbiome and implications for human health.
  Journal of translational medicine 2017 Singh RK, Chang HW, Yan D, Lee KM, Ucmak D, Wong K, Abrouk M, Farahnik B, Nakamura M, Zhu TH, Bhutani T, Liao W
• Warfarin-Associated Nonuremic Calciphylaxis.
  JAMA dermatology 2017 Yu WY, Bhutani T, Kornik R, Pincus LB, Mauro T, Rosenblum MD, Fox LP
• Considerations on biologic agents in psoriasis with the new pregnancy lactation labeling rule.
  International journal of women's dermatology 2017 Abrouk M, Beroukhim K, Nakamura M, Zhu TH, Farahnik B, Singh R, Lee K, Koo J, Bhutani T
• Excimer laser for the treatment of psoriasis: safety, efficacy, and patient acceptability.
  Psoriasis (Auckland, N.Z.) 2016 Abrouk M, Levin E, Brodsky M, Gandy JR, Nakamura M, Zhu TH, Farahnik B, Koo J, Bhutani T
• Successful use of a modified Goeckerman regimen in the treatment of chronic severe atopic dermatitis: A prospective pilot study.
  Journal of the American Academy of Dermatology 2016 Farahnik B, Beroukhim K, Danesh M, Nakamura M, Abrouk M, Zhu TH, Singh R, Lee K, Bhutani T, Koo J
• Obsessive-compulsive skin disorders: a novel classification based on degree of insight.
  The Journal of dermatological treatment 2016 Zhu TH, Nakamura M, Farahnik B, Abrouk M, Reichenberg J, Bhutani T, Koo J
• Eczema as an adverse effect of anti-TNFα therapy in psoriasis and other Th1-mediated diseases: a review.
  The Journal of dermatological treatment 2016 Nakamura M, Lee K, Singh R, Zhu TH, Farahnik B, Abrouk M, Koo J, Bhutani T
• Uremic pruritus treated successfully with the Goeckerman Program.
  Dermatology online journal 2016 Nakamura M, Koo J, Bhutani T
• The Patient's Guide to Psoriasis Treatment. Part 1: UVB Phototherapy.
  Dermatology and therapy 2016 Singh RK, Lee KM, Jose MV, Nakamura M, Ucmak D, Farahnik B, Abrouk M, Zhu TH, Bhutani T, Liao W
• The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy.
  Dermatology and therapy 2016 Farahnik B, Nakamura M, Singh RK, Abrouk M, Zhu TH, Lee KM, Jose MV, DaLovisio R, Koo J, Bhutani T, Liao W
• The Patient's Guide to Psoriasis Treatment. Part 3: Biologic Injectables.
  Dermatology and therapy 2016 Abrouk M, Nakamura M, Zhu TH, Farahnik B, Singh RK, Lee KM, Jose MV, Koo J, Bhutani T, Liao W
• The Patient's Guide to Psoriasis Treatment. Part 4: Goeckerman Therapy.
  Dermatology and therapy 2016 Zhu TH, Nakamura M, Farahnik B, Abrouk M, Singh RK, Lee KM, Hulse S, Koo J, Bhutani T, Liao W
• Combining biologic and phototherapy treatments for psoriasis: safety, efficacy, and patient acceptability.
  Psoriasis (Auckland, N.Z.) 2016 Farahnik B, Patel V, Beroukhim K, Zhu TH, Abrouk M, Nakamura M, Singh R, Lee K, Bhutani T, Koo J
• Recent advances in phototherapy for psoriasis.
  F1000Research 2016 Nakamura M, Farahnik B, Bhutani T
• Narrowband UVB-induced iatrogenic polymorphous light eruption: a case and suggestions to overcome this rare complication.
  Dermatology online journal 2016 Nakamura M, Bhutani T, Koo JY
• The Role of the Nervous System in the Pathophysiology of Psoriasis: A Review of Cases of Psoriasis Remission or Improvement Following Denervation Injury.
  American journal of clinical dermatology 2016 Zhu TH, Nakamura M, Farahnik B, Abrouk M, Lee K, Singh R, Gevorgyan A, Koo J, Bhutani T
• Brodalumab for the Treatment of Psoriasis: A Review of Phase III Trials.
  Dermatology and therapy 2016 Farahnik B, Beroukhim K, Abrouk M, Nakamura M, Zhu TH, Singh R, Lee K, Bhutani T, Koo J
• Considerations on biologic agents in psoriasis with the new pregnancy lactation labeling rule.
  International journal of women's dermatology 2016 Abrouk M, Beroukhim K, Nakamura M, Zhu TH, Farahnik B, Singh R, Brodsky M, Lee K, Koo J, Bhutani T
• Anti-IL-17 Agents for Psoriasis: A Review of Phase III Data.
  Journal of drugs in dermatology : JDD 2016 Farahnik B, Beroukhim K, Nakamura M, Abrouk M, Zhu TH, Singh R, Lee K, Bhutani T, Koo J
• Ixekizumab for the Treatment of Psoriasis: A Review of Phase III Trials.
  Dermatology and therapy 2016 Farahnik B, Beroukhim K, Zhu TH, Abrouk M, Nakamura M, Singh R, Lee K, Bhutani T, Koo J