Tilo Thottakara, MD
Postdoctoral Scholar
Medicine
School of Medicine

Publications (8)

Top publication keywords:
Cardiomegaly, Exercise-InducedFibrosisSoccerAdaptor Proteins, Signal TransducingAthletesVentricular Function, RightSwimmingMicroRNAsBicyclingMyocardiumMyocytes, CardiacHeart VentriclesDesminBiomarkersCardiomyopathy, Hypertrophic

• Single-nucleus RNA/ATAC-seq in early-stage HCM models predicts SWI/SNF-activation in mutant-myocytes, and allele-specific differences in fibroblasts.
  bioRxiv : the preprint server for biology 2024 Thottakara T, Padmanabhan A, Tanriverdi T, Thambidurai T, Diaz-Rg JA, Amonkar SR, Olgin JE, Long CS, Roselle Abraham M
• Allele-specific dysregulation of lipid and energy metabolism in early-stage hypertrophic cardiomyopathy.
  Journal of molecular and cellular cardiology plus 2024 Vaniya A, Karlstaedt A, Gulkok D, Thottakara T, Liu Y, Fan S, Eades H, Vakrou S, Fukunaga R, Vernon HJ, Fiehn O, Roselle Abraham M
• Lipid metabolism drives allele-specific early-stage hypertrophic cardiomyopathy.
  bioRxiv : the preprint server for biology 2023 Vaniya A, Karlstaedt A, Gulkok DA, Thottakara T, Liu Y, Fan S, Eades H, Fukunaga R, Vernon HJ, Fiehn O, Roselle Abraham M
• A Novel miRNA Screen Identifies miRNA-4454 as a Candidate Biomarker for Ventricular Fibrosis in Patients with Hypertrophic Cardiomyopathy.
  Biomolecules 2021 Thottakara T, Lund N, Krämer E, Kirchhof P, Carrier L, Patten M
• Cytokine-Mediated Alterations of Human Cardiac Fibroblast's Secretome.
  International journal of molecular sciences 2021 Bräuninger H, Thottakara T, Schön J, Voss S, Dhople V, Warnke S, Scherschel K, Schrage B, Kirchhof P, Blankenberg S, Völker U, Westermann D, Hammer E, Lindner D
• Increased myocardial mass and attenuation of myocardial strain in professional male soccer players and competitive male triathletes.
  The international journal of cardiovascular imaging 2020 Starekova J, Thottakara T, Lund GK, Welsch GH, Brunner FJ, Muellerleile K, Adam G, Regier M, Tahir E
• S100A4 as a Target of the E3-Ligase Asb2β and Its Effect on Engineered Heart Tissue.
  Frontiers in physiology 2018 Braumann S, Thottakara T, Stücker S, Reischmann-Düsener S, Krämer E, Groß J, Hirt MN, Doroudgar S, Carrier L, Friedrich FW
• The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation.
  Journal of molecular and cellular cardiology 2015 Thottakara T, Friedrich FW, Reischmann S, Braumann S, Schlossarek S, Krämer E, Juhr D, Schlüter H, van der Velden J, Münch J, Patten M, Eschenhagen T, Moog-Lutz C, Carrier L