Thomas Hope, MD
Professor
Radiology
School of Medicine

415-221-4810 ext. 22648

Thomas Hope, MD, is the Vice Chair of Clinical Operations and Strategy in the Department of Radiology. He also serves as the Director of Molecular Therapy. He serves as Chief of Nuclear Medicine at the San Francisco VA Medical Center and as chair of the Cancer Center’s Molecular Imaging & Radionuclide Therapy Site Committee.

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In 2007, he received his medical degree from Stanford University School of Medicine and he completed a one-year internship at Kaiser Permanente, San Francisco. From 2008-2012, Dr. Hope completed a residency in Diagnostic Radiology at the University of California, San Francisco, followed by a clinical fellowship in Body MRI and Nuclear Medicine from Stanford Medical Center in 2013.

Dr. Hope’s main research focus is on novel imaging agents and therapies, particularly in prostate cancer and neuroendocrine tumors. He lead the development of Ga-68 PSMA-11, which subsequently led to the approval of this drug by the FDA. He has combined his interest in MR imaging with PET in the simultaneous modality PET/MRI, helping lead the development of the clinical PET/MRI program. Additionally he leads the PRRT (peptide receptor radionuclide therapy) program for neuroendocrine tumors and PSMA Radioligand Therapy at UCSF.

An international leader in PET/MR research and the translation of new molecular imaging agents, Dr. Hope launched the highly successful PSMA prostate program at UCSF and championed the use of multiple new targeted therapies to treat patients with neuroendocrine and other tumors. He current serves as principal investigator on grants from the NIH, the Prostate Cancer Foundation. He is the recipient of numerous accolades in molecular imaging, including the Henkin Fellow and Marc Tetalman Memorial Award from the Society of Nuclear Medicine and Molecular Imaging, the Young Investigator Award from the Prostate Cancer Foundation and the Wylie J. Dodds Research Award from the Society of Abdominal Radiology.

Expertise: Abdominal Imaging and Nuclear Medicine, and Molecular Imaging and Therapeutics

Professional Interests: Novel imaging agents, PET/MR, prostate cancer, neuroendocrine tumor, radioligand therapy

Education and Training:

  • Medical School: Stanford University School of Medicine, California
  • Internship: Kaiser Permanente, San Francisco, California
  • Residency: University of California, San Francisco - Diagnostic Radiology
  • Fellowship: Stanford Medical Center, California - Body MRI and Nuclear Medicine
  • California Medical License
  • American Board of Radiology, Certificate in Diagnostic Radiology
  • American Board of Nuclear Medicine, Certificate in Nuclear Medicine

Awards

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  • Hal O’Brien Rising Star Award Winner, Society of Nuclear Medicine and Molecular Imaging, 2020
  • Theragnostics Investigator Award, North American Neuroendocrine Tumor Society, 2018
  • Young Investigator Award, Prostate Cancer Foundation, 2017
  • Henkin Fellowship, Society of Nuclear Medicine and Molecular Imaging, 2016
  • Marc Tetalman Award, Society of Nuclear Medicine and Molecular Imaging, 2016
  • Wylie J. Dodds Research Award, Society of Abdominal Radiology, 2014
  • Roentgen Resident/Fellow Research Award, Radiological Society of North America, 2012
  • Alexander Margulis Society Outstanding Research Award, University of California, San Francisco, 2012
  • Presidents Circle Research Resident Grant, Radiological Society of North America, 2010
  • W.S. Moore Award Nominee, ISMRM, 2007
  • Trainee Research Prize, Radiological Society of North America, 2006

Interests

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  • MRI techniques
  • Peptide Receptor Radionuclide Therapy
  • PET/MRI
  • PSMA PET and Radioligand Therapy
  • Novel molecular imaging agents

Websites

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Grants and Projects

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Publications (229)

Top publication keywords:
OctreotideMultimodal ImagingNeuroendocrine TumorsEdetic AcidGadolinium DTPAProstate-Specific AntigenGlutamate Carboxypeptidase IIPositron Emission Tomography Computed TomographyOrganometallic CompoundsPositron-Emission TomographyNuclear MedicineReceptors, SomatostatinRadiopharmaceuticalsGallium RadioisotopesProstatic Neoplasms

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