Thierry Jahan, MD
Professor Emeritus
Medicine
School of Medicine

Education & Training

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• Fellowship Hematology/Oncology University of California, San Francisco 06/1994
• Kennamer Fellowship Internal Medicine University of California, Los Angeles 06/1991
• Residency Internal Medicine University of California, Los Angeles 06/1990
• MD George Washington University School of Medicine and Health Sciences 06/1987
• BA Psychology Columbia University 05/1983

Websites

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• Clinical Profile at UCSF Medical Center (ucsfhealth.org)

Publications (59)

Top publication keywords:
Thymus NeoplasmsLung NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsPyridinesNeoplasm StagingPhthalazinesGPI-Linked ProteinsCarcinoma, Large CellSarcomaCarcinoma, Non-Small-Cell LungSMARCB1 ProteinAngiogenesis InhibitorsPleural NeoplasmsMesotheliomaProtein Kinase Inhibitors

• First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma (CheckMate 743): a multicentre, randomised, open-label, phase 3 trial.
  Lancet (London, England) 2021 Baas P, Scherpereel A, Nowak AK, Fujimoto N, Peters S, Tsao AS, Mansfield AS, Popat S, Jahan T, Antonia S, Oulkhouir Y, Bautista Y, Cornelissen R, Greillier L, Grossi F, Kowalski D, Rodríguez-Cid J, …
• Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study.
  The Lancet. Oncology 2020 Gounder M, Schöffski P, Jones RL, Agulnik M, Cote GM, Villalobos VM, Attia S, Chugh R, Chen TW, Jahan T, Loggers ET, Gupta A, Italiano A, Demetri GD, Ratan R, Davis LE, Mir O, Dileo P, Van Tine BA, …
• Evaluation of a National Comprehensive Cancer Network Guidelines-Based Decision Support Tool in Patients With Non-Small Cell Lung Cancer: A Nonrandomized Clinical Trial.
  JAMA network open 2020 Wu SY, Lazar AA, Gubens MA, Blakely CM, Gottschalk AR, Jablons DM, Jahan TM, Wang VEH, Dunbar TL, Wong ML, Chan JW, Guthrie W, Belkora J, Yom SS
• Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing.
  Cell 2020 Maynard A, McCoach CE, Rotow JK, Harris L, Haderk F, Kerr DL, Yu EA, Schenk EL, Tan W, Zee A, Tan M, Gui P, Lea T, Wu W, Urisman A, Jones K, Sit R, Kolli PK, Seeley E, Gesthalter Y, Le DD, Yamauchi KA…
• Clinical Response of Live-Attenuated, Listeria monocytogenes Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Hassan R, Alley E, Kindler H, Antonia S, Jahan T, Honarmand S, Nair N, Whiting CC, Enstrom A, Lemmens E, Tsujikawa T, Kumar S, Choe G, Thomas A, McDougall K, Murphy AL, Jaffee E, Coussens LM, …

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• Incorporation of a Molecular Prognostic Classifier Improves Conventional Non-Small Cell Lung Cancer Staging.
  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2019 Kratz JR, Haro GJ, Cook NR, He J, Van Den Eeden SK, Woodard GA, Gubens MA, Jahan TM, Jones KD, Kim IJ, He B, Jablons DM, Mann MJ
• Distinct attentional function profiles in older adults receiving cancer chemotherapy.
  European journal of oncology nursing : the official journal of European Oncology Nursing Society 2018 Utne I, Løyland B, Grov EK, Rasmussen HL, Torstveit AH, Cooper BA, Mastick J, Mazor M, Wong M, Paul SM, Conley YP, Jahan T, Ritchie C, Levine JD, Miaskowski C
• Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2018 Kindler HL, Ismaila N, Armato SG, Bueno R, Hesdorffer M, Jahan T, Jones CM, Miettinen M, Pass H, Rimner A, Rusch V, Sterman D, Thomas A, Hassan R
• Adjuvant Chemotherapy Guided by Molecular Profiling and Improved Outcomes in Early Stage, Non-Small-Cell Lung Cancer.
  Clinical lung cancer 2017 Woodard GA, Wang SX, Kratz JR, Zoon-Besselink CT, Chiang CY, Gubens MA, Jahan TM, Blakely CM, Jones KD, Mann MJ, Jablons DM
• Inhibiting Histone Deacetylase as a Means to Reverse Resistance to Angiogenesis Inhibitors: Phase I Study of Abexinostat Plus Pazopanib in Advanced Solid Tumor Malignancies.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017 Aggarwal R, Thomas S, Pawlowska N, Bartelink I, Grabowsky J, Jahan T, Cripps A, Harb A, Leng J, Reinert A, Mastroserio I, Truong TG, Ryan CJ, Munster PN
• NCCN Guidelines Insights: Malignant Pleural Mesothelioma, Version 3.2016.
  Journal of the National Comprehensive Cancer Network : JNCCN 2016 Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D'Amico TA, Dilling T, Dobelbower M, Govindan R, Hennon M, Horn L, Jahan TM, Komaki R, Lackner RP, Lanuti…
• NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 4.2016.
  Journal of the National Comprehensive Cancer Network : JNCCN 2016 Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D'Amico TA, Dilling TJ, Dobelbower MC, Govindan R, Hennon M, Horn L, Jahan TM, Komaki R, Lackner RP, …
• Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma.
  Sarcoma 2015 Tinkle CL, Weinberg V, Braunstein SE, Wustrack R, Horvai A, Jahan T, O'Donnell RJ, Gottschalk AR
• Non-Small Cell Lung Cancer, Version 6.2015.
  Journal of the National Comprehensive Cancer Network : JNCCN 2015 Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Dilling TJ, Dobelbower MC, Govindan R, Grannis FW, Horn L, Jahan TM, Komaki R, Krug…
• Non-small cell lung cancer, version 1.2015.
  Journal of the National Comprehensive Cancer Network : JNCCN 2014 Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Dilling TJ, Govindan R, Grannis FW, Horn L, Jahan TM, Komaki R, Kris MG, Krug LM, …
• A phase II, open-label study of ramucirumab in combination with paclitaxel and carboplatin as first-line therapy in patients with stage IIIB/IV non-small-cell lung cancer.
  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2014 Camidge DR, Berge EM, Doebele RC, Ballas MS, Jahan T, Haigentz M, Hoffman D, Spicer J, West H, Lee P, Yang L, Joshi A, Gao L, Yurasov S, Mita A
• Phase II clinical trial of amatuximab, a chimeric antimesothelin antibody with pemetrexed and cisplatin in advanced unresectable pleural mesothelioma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Hassan R, Kindler HL, Jahan T, Bazhenova L, Reck M, Thomas A, Pastan I, Parno J, O'Shannessy DJ, Fatato P, Maltzman JD, Wallin BA
• Prognostic molecular assay might improve identification of patients at risk for recurrence in early-stage non-small-cell lung cancer.
  Clinical lung cancer 2014 Woodard GA, Gubens MA, Jahan TM, Jones KD, Kukreja J, Theodore PR, Cardozo S, Jew G, Clary-Macy C, Jablons DM, Mann MJ
• Divergent management strategies for typical versus atypical carcinoid tumors of the thoracic cavity.
  American journal of clinical oncology 2014 Okoye CC, Jablons DM, Jahan TM, Kukreja J, Cardozo S, Yom SS
• The impact of a fourteen-gene molecular assay on physician treatment decisions in non-small-cell lung cancer.
  International journal of clinical oncology 2014 Dormady S, Broder MS, Putcha GV, Dumanois RH, DeCristofaro AH, Chang E, Billings PR, Jahan T
• Aggressive and minimally invasive surgery for pulmonary metastasis of sarcoma.
  The Journal of thoracic and cardiovascular surgery 2014 Reza J, Sammann A, Jin C, Horvai A, Hudnall M, Jablons DM, Jahan T, Kornak J, Mann MJ
• A novel use of foley catheters to prevent injury to the pelvic viscera during stereotactic radiosurgery for undifferentiated pleomorphic sarcoma of the sacrum.
  The Permanente journal 2014 Maa J, Waterford S, Jahan T, Larson DA, Chou D
• VATS lobectomy facilitates the delivery of adjuvant docetaxel-carboplatin chemotherapy in patients with non-small cell lung cancer.
  Journal of thoracic disease 2013 Zhi X, Gao W, Han B, Yang Y, Li H, Liu D, Wang C, Min G, Long H, Rigas JR, Carey M, Jahan T, Sammann A, Reza J, Wang D, Mann MJ, Jablons DM, He J, China Clinical Trials Consortium
• Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement: report of 2 cases.
  Journal of neurosurgery. Spine 2013 Lau D, Yarlagadda J, Jahan T, Jablons D, Chou D
• Non-small cell lung cancer, version 2.2013.
  Journal of the National Comprehensive Cancer Network : JNCCN 2013 Ettinger DS, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, Grannis FW, Grant SC, Horn L, Jahan TM, Komaki R, Kong FM, Kris MG, Krug LM, Lackner RP, Lennes …
• Thymomas and thymic carcinomas: Clinical Practice Guidelines in Oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2013 Ettinger DS, Riely GJ, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, Grannis FW, Grant SC, Horn L, Jahan TM, Komaki R, Kong FM, Kris MG, Krug LM, Lackner …
• Small cell lung cancer.
  Journal of the National Comprehensive Cancer Network : JNCCN 2013 Kalemkerian GP, Akerley W, Bogner P, Borghaei H, Chow LQ, Downey RJ, Gandhi L, Ganti AK, Govindan R, Grecula JC, Hayman J, Heist RS, Horn L, Jahan T, Koczywas M, Loo BW, Merritt RE, Moran CA, Niell HB…
• Non-small cell lung cancer.
  Journal of the National Comprehensive Cancer Network : JNCCN 2012 Ettinger DS, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Ganti AK, Govindan R, Grannis FW, Horn L, Jahan TM, Jahanzeb M, Kessinger A, Komaki R, Kong FM, Kris MG, …
• Determination of cutpoints for low and high number of symptoms in patients with advanced cancer.
  Journal of palliative medicine 2012 Gilbertson-White S, Aouizerat BE, Jahan T, Paul SM, West C, Schumacher K, Dodd MJ, Rabow M, Abu Raddaha AH, Miaskowski C
• A phase II study of enzastaurin in combination with erlotinib in patients with previously treated advanced non-small cell lung cancer.
  Lung cancer (Amsterdam, Netherlands) 2012 Clément-Duchêne C, Natale RB, Jahan T, Krupitskaya Y, Osarogiagbon R, Sanborn RE, Bernstein ED, Dudek AZ, Latz JE, Shi P, Wakelee HA
• One size does not fit all lung cancer patients.
  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012 Yom SS, Chen CP, Jahan TM, Jablons DM
• Impact of age and comorbidity on non-small-cell lung cancer treatment in older veterans.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012 Wang S, Wong ML, Hamilton N, Davoren JB, Jahan TM, Walter LC
• A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies.
  Lancet (London, England) 2012 Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal MR, Ray MR, Jones…
• Malignant pleural mesothelioma.
  Journal of the National Comprehensive Cancer Network : JNCCN 2012 Ettinger DS, Akerley W, Borghaei H, Chang A, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Ganti AK, Govindan R, Grannis FW, Horn L, Jahan TM, Jahanzeb M, Kessinger A, Komaki R, Kong FM, Kris MG, Krug…
• Vatalanib in malignant mesothelioma: a phase II trial by the Cancer and Leukemia Group B (CALGB 30107).
  Lung cancer (Amsterdam, Netherlands) 2011 Jahan T, Gu L, Kratzke R, Dudek A, Otterson GA, Wang X, Green M, Vokes EE, Kindler HL
• Implications of delayed initiation of radiotherapy: accelerated repopulation after induction chemotherapy for stage III non-small cell lung cancer.
  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011 Chen CP, Weinberg VK, Jahan TM, Jablons DM, Yom SS
• Emerging antiangiogenic therapies for non-small-cell lung cancer.
  Expert review of anticancer therapy 2011 Blakely C, Jahan T
• Small cell lung cancer.
  Journal of the National Comprehensive Cancer Network : JNCCN 2011 Kalemkerian GP, Akerley W, Bogner P, Borghaei H, Chow L, Downey RJ, Gandhi L, Ganti AK, Govindan R, Grecula JC, Hayman J, Heist RS, Horn L, Jahan TM, Koczywas M, Moran CA, Niell HB, O'Malley J, Patel …
• Lung cancer stigma, depression, and quality of life among ever and never smokers.
  European journal of oncology nursing : the official journal of European Oncology Nursing Society 2011 Cataldo JK, Jahan TM, Pongquan VL
• A review of the literature on multiple symptoms, their predictors, and associated outcomes in patients with advanced cancer.
  Palliative & supportive care 2011 Gilbertson-White S, Aouizerat BE, Jahan T, Miaskowski C
• Measuring stigma in people with lung cancer: psychometric testing of the cataldo lung cancer stigma scale.
  Oncology nursing forum 2011 Cataldo JK, Slaughter R, Jahan TM, Pongquan VL, Hwang WJ
• Thymic malignancies.
  Journal of the National Comprehensive Cancer Network : JNCCN 2010 Ettinger DS, Akerley W, Bepler G, Blum MG, Chang A, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, Grannis FW, Jahan T, Johnson DH, Kessinger A, Komaki R, Kong FM, Kris MG, Krug LM, Le QT, …
• Non-small cell lung cancer.
  Journal of the National Comprehensive Cancer Network : JNCCN 2010 Ettinger DS, Akerley W, Bepler G, Blum MG, Chang A, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Ganti AK, Govindan R, Grannis FW, Jahan T, Jahanzeb M, Johnson DH, Kessinger A, Komaki R, Kong FM, …
• Differences in symptom clusters identified using occurrence rates versus symptom severity ratings in patients at the end of radiation therapy.
  Cancer nursing 2009 Kim E, Jahan T, Aouizerat BE, Dodd MJ, Cooper BA, Paul SM, West C, Lee K, Swift PS, Wara W, Miaskowski C
• A phase I study of a 2-day lapatinib chemosensitization pulse preceding nanoparticle albumin-bound Paclitaxel for advanced solid malignancies.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Chien AJ, Illi JA, Ko AH, Korn WM, Fong L, Chen LM, Kashani-Sabet M, Ryan CJ, Rosenberg JE, Dubey S, Small EJ, Jahan TM, Hylton NM, Yeh BM, Huang Y, Koch KM, Moasser MM
• Changes in symptom clusters in patients undergoing radiation therapy.
  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2009 Kim E, Jahan T, Aouizerat BE, Dodd MJ, Cooper BA, Paul SM, West C, Lee K, Swift PS, Wara W, Miaskowski C
• Impact of preoperative chemotherapy on pulmonary function tests in resectable early-stage non-small cell lung cancer.
  Chest 2009 Rivera MP, Detterbeck FC, Socinski MA, Moore DT, Edelman MJ, Jahan TM, Ansari RH, Luketich JD, Peng G, Monberg M, Obasaju CK, Gralla RJ
• A review of the prevalence and impact of multiple symptoms in oncology patients.
  Journal of pain and symptom management 2008 Esther Kim JE, Dodd MJ, Aouizerat BE, Jahan T, Miaskowski C
• Assessing quality of life following neoadjuvant therapy for early stage non-small cell lung cancer (NSCLC): results from a prospective analysis using the Lung Cancer Symptom Scale (LCSS).
  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2008 Gralla RJ, Edelman MJ, Detterbeck FC, Jahan TM, Loesch DM, Limentani SA, Govindan R, Peng G, Monberg MJ, Obasaju CK, Socinski MA
• Non-small cell lung cancer.
  Journal of the National Comprehensive Cancer Network : JNCCN 2008 Ettinger DS, Akerley W, Bepler G, Chang A, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Feigenberg SJ, Figlin RA, Govindan R, Grannis FW, Jahan T, Jahanzeb M, Kessinger A, Komaki R, Kris MG, Langer …
• Small cell lung cancer.
  Journal of the National Comprehensive Cancer Network : JNCCN 2008 Kalemkerian GP, Akerley W, Downey RJ, Ettinger DS, Fossella F, Grecula JC, Jahan T, Johnson BE, Kessinger A, Koczywas M, Langer CJ, Martins R, Niell HB, Pan CC, Ramnath N, Ready N, Robert F, Williams …
• Neoadjuvant chemotherapy with gemcitabine-containing regimens in patients with early-stage non-small cell lung cancer.
  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008 Detterbeck FC, Socinski MA, Gralla RJ, Edelman MJ, Jahan TM, Loesch DM, Limentani SA, Govindan R, Zaman MB, Ye Z, Monberg MJ, Obasaju CK
• Risk of cerebral metastases and neurological death after pathological complete response to neoadjuvant therapy for locally advanced nonsmall-cell lung cancer: clinical implications for the subsequent management of the brain.
  Cancer 2007 Chen AM, Jahan TM, Jablons DM, Garcia J, Larson DA
• Malignant pheochromocytomas and paragangliomas: a phase II study of therapy with high-dose 131I-metaiodobenzylguanidine (131I-MIBG).
  Annals of the New York Academy of Sciences 2006 Fitzgerald PA, Goldsby RE, Huberty JP, Price DC, Hawkins RA, Veatch JJ, Dela Cruz F, Jahan TM, Linker CA, Damon L, Matthay KK
• Non-small cell lung cancer clinical practice guidelines in oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2006 Ettinger DS, Bepler G, Bueno R, Chang A, Chang JY, Chirieac LR, D'Amico TA, Demmy TL, Feigenberg SJ, Grannis FW, Jahan T, Jahanzeb M, Kessinger A, Komaki R, Kris MG, Langer CJ, Le QT, Martins R, …
• Small cell lung cancer clinical practice guidelines in oncology.
  Journal of the National Comprehensive Cancer Network : JNCCN 2006 Johnson BE, Crawford J, Downey RJ, Ettinger DS, Fossella F, Grecula JC, Jahan T, Kalemkerian GP, Kessinger A, Koczywas M, Langer CJ, Martins R, Marymont MH, Niell HB, Ramnath N, Robert F, Williams CC,…
• Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Taron M, Ichinose Y, Rosell R, Mok T, Massuti B, Zamora L, Mate JL, Manegold C, Ono M, Queralt C, Jahan T, Sanchez JJ, Sanchez-Ronco M, Hsue V, Jablons D, Sanchez JM, Moran T
• Unusual thoracic problems in patients with malignancies: case 3. Carcinoid tumor of the thymus.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 Hansen EK, Krieg RM, Azar RJ, Jablons DM, Jahan TM, Zaloudek CJ
• Mechanisms of and potential treatment strategies for metastatic disease in non-small cell lung cancer.
  Seminars in thoracic and cardiovascular surgery 2004 Maslyar DJ, Jahan TM, Jablons DM