Theodore Miclau, MD
Professor
Orthopaedic Surgery
School of Medicine

Education & Training

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• Diversity, Equity, and Inclusion Champion Training University of California 2019

Grants and Projects

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• Mechanisms of Skeletal Stem Cell Dysfunctions in Traumatic Bone Injuries, NIH, 2018-2023
• Understanding the Global Burden of Disease of Skeletal Fractures: the International Orthopaedic Multi-Center Study (INORMUS), NIH, 2020-2022
• A Murine Model of Polytrauma: Understanding the molecular basis of accelerated bone repair with concomitant traumatic brain injury, NIH, 2015-2017
• Functional roles of muscle in bone repair, NIH, 2010-2016
• Biology of stable and non-stable fracture repair, NIH, 2006-2011
• Role of Angiogenesis in Bone Repair, NIH, 2000-2006

Publications (36)

Top publication keywords:
Fractures, UnunitedSpinal FracturesMinimally Invasive Surgical ProceduresLeadershipTibial FracturesMultiple TraumaFracture HealingDeveloping CountriesMusculoskeletal DiseasesBone PlatesFemoral Neck FracturesFractures, BoneFracture Fixation, InternalMusculoskeletal SystemSpinal Cord Injuries

• Open fractures: Current treatment perspective.
  OTA international : the open access journal of orthopaedic trauma 2023 Minehara H, Maruo A, Amadei R, Contini A, Braile A, Kelly M, Jenner L, Schemitsch GW, Schemitsch EH, Miclau T
• A Shifting Paradigm: Transformation of Cartilage to Bone during Bone Repair.
  Journal of dental research 2022 Marcucio RS, Miclau T, Bahney CS
• Leadership development programs for healthcare professionals in low-and middle-income countries: A systematic review.
  The International journal of health planning and management 2022 MacKechnie MC, Miclau TA, Cordero DM, Tahir P, Miclau T
• Appendicular Fracture and Polytrauma Correlate with Outcome of Spinal Cord Injury: A Transforming Research and Clinical Knowledge in Spinal Cord Injury Study.
  Journal of neurotrauma 2022 Miclau TA, Torres-Espin A, Morshed S, Morioka K, Huie JR, El Naga AN, Chou A, Pascual L, Duong-Fernandez X, Kuo YH, Weinstein P, Dhall SS, Bresnahan JC, Beattie MS, Digiorgio A, Ferguson AR, …
• Collagen X Longitudinal Fracture Biomarker Suggests Staged Fixation in Tibial Plateau Fractures Delays Rate of Endochondral Repair.
  Journal of orthopaedic trauma 2022 Working ZM, Peterson D, Lawson M, O'Hara K, Coghlan R, Provencher MT, Friess DM, Johnstone B, Miclau T, Bahney CS

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• Smith-Petersen Versus Watson-Jones Approach Does Not Affect Quality of Open Reduction of Femoral Neck Fracture.
  Journal of orthopaedic trauma 2021 Patterson JT, Ishii K, Tornetta P, Leighton RK, Friess DM, Jones CB, Levine A, Maclean JJ, Miclau T, Mullis BH, Obremskey WT, Ostrum RF, Reid JS, Ruder JA, Saleh A, Schmidt AH, Teague DC, Tsismenakis …
• Cost Minimization Analysis of a Teledermatology Triage System in a Managed Care Setting.
  JAMA dermatology 2021 Zakaria A, Miclau TA, Maurer T, Leslie KS, Amerson E
• Open Tibial Shaft Fractures: Treatment Patterns in Latin America.
  The Journal of bone and joint surgery. American volume 2020 Albright PD, MacKechnie MC, Roberts HJ, Shearer DW, Padilla Rojas LG, Segovia J, Quintero JE, Amadei R, Baldy Dos Reis F, Miclau T, and the ACTUAR Open Tibia Study Group
• Motivations and impact of international rotations in low- and middle-income countries for orthopaedic surgery residents: Are we on the same page?
  American journal of surgery 2020 Roberts HJ, Albright PD, Shearer DW, Won N, MacKechnie MC, Richard Coughlin R, Miclau T, Morshed S, Sabharwal S, COACT Resident Rotation Study Group
• The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union.
  JBJS reviews 2020 Hellwinkel JE, Miclau T, Provencher MT, Bahney CS, Working ZM
• A quantitative serum biomarker of circulating collagen X effectively correlates with endochondral fracture healing.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Working ZM, Morris ER, Chang JC, Coghlan RF, Johnstone B, Miclau T, Horton WA, Bahney CS
• Open Reduction Is Associated With Greater Hazard of Early Reoperation After Internal Fixation of Displaced Femoral Neck Fractures in Adults 18-65 Years.
  Journal of orthopaedic trauma 2020 Patterson JT, Ishii K, Tornetta P, Leighton RK, Friess DM, Jones CB, Levine A, Maclean JJ, Miclau T, Mullis BH, Obremskey WT, Ostrum RF, Reid JS, Ruder JA, Saleh A, Schmidt AH, Teague DC, Tsismenakis …
• Optimizing Patient Function After Musculoskeletal Trauma: An Introduction.
  Injury 2020 Miclau T, Van Lieshout EMM
• The global burden of musculoskeletal injury in low and lower-middle income countries: A systematic literature review.
  OTA international : the open access journal of orthopaedic trauma 2020 Cordero DM, Miclau TA, Paul AV, Morshed S, Miclau T, Martin C, Shearer DW
• Knowledge deficits and barriers to performing soft-tissue coverage procedures: An analysis of participants in an orthopaedic surgical skills training course in Mexico.
  OTA international : the open access journal of orthopaedic trauma 2019 Albright PD, Mackechnie MC, Jackson JH, Chopra A, Holler JT, Flores Biard A, Padilla Rojas LG, Morshed S, Miclau T, Shearer DW, Terry MJ
• Differential fracture response to traumatic brain injury suggests dominance of neuroinflammatory response in polytrauma.
  Scientific reports 2019 Morioka K, Marmor Y, Sacramento JA, Lin A, Shao T, Miclau KR, Clark DR, Beattie MS, Marcucio RS, Miclau T, Ferguson AR, Bresnahan JC, Bahney CS
• Minimally invasive plate osteosynthesis versus conventional open insertion techniques for osteosynthesis.
  Injury 2018 Toogood P, Huang A, Siebuhr K, Miclau T
• Microenvironmental Regulation of Chondrocyte Plasticity in Endochondral Repair-A New Frontier for Developmental Engineering.
  Frontiers in bioengineering and biotechnology 2018 Wong SA, Rivera KO, Miclau T, Alsberg E, Marcucio RS, Bahney CS
• Fracture healing: A review of clinical, imaging and laboratory diagnostic options.
  Injury 2017 Cunningham BP, Brazina S, Morshed S, Miclau T
• Barriers to Clinical Research in Latin America.
  Frontiers in public health 2017 Chomsky-Higgins K, Miclau TA, Mackechnie MC, Aguilar D, Avila JR, Dos Reis FB, Balmaseda R, Barquet A, Ceballos A, Contreras F, Escalante I, Elias N, Vincenti SI, Lozano C, Medina F, Merchan G, …
• Stem Cell Therapies in Orthopaedic Trauma.
  Journal of orthopaedic trauma 2015 Marcucio RS, Nauth A, Giannoudis PV, Bahney C, Piuzzi NS, Muschler G, Miclau T
• The multifaceted role of the vasculature in endochondral fracture repair.
  Frontiers in endocrinology 2015 Bahney CS, Hu DP, Miclau T, Marcucio RS
• Modulation of macrophage activity during fracture repair has differential effects in young adult and elderly mice.
  Journal of orthopaedic trauma 2014 Slade Shantz JA, Yu YY, Andres W, Miclau T, Marcucio R
• Status of road safety and injury burden: North America.
  Journal of orthopaedic trauma 2014 Shearer D, Morshed S, Miclau T
• Acute complications of patients with pelvic fractures after pelvic angiographic embolization.
  Clinical orthopaedics and related research 2013 Matityahu A, Marmor M, Elson JK, Lieber C, Rogalski G, Lin C, Belaye T, Miclau T, Kandemir U
• Beneficial effects of oxygen- and lactate-production in scaffold designs.
  Bone 2013 Marcucio R, Hunt TK, Miclau T
• Creating rigidly stabilized fractures for assessing intramembranous ossification, distraction osteogenesis, or healing of critical sized defects.
  Journal of visualized experiments : JoVE 2012 Yu YY, Bahney C, Hu D, Marcucio RS, Miclau T
• Use of osteobiologics in the management of osteoporotic fractures.
  Journal of orthopaedic trauma 2011 Nauth A, Miclau T, Bhandari M, Schemitsch EH
• Rejuvenation of the inflammatory system stimulates fracture repair in aged mice.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010 Xing Z, Lu C, Hu D, Miclau T, Marcucio RS
• Action of IL-1beta during fracture healing.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2010 Lange J, Sapozhnikova A, Lu C, Hu D, Li X, Miclau T, Marcucio RS
• Gene therapy for fracture healing.
  Journal of orthopaedic trauma 2010 Nauth A, Miclau T, Li R, Schemitsch EH
• Delayed internal fixation of femoral shaft fracture reduces mortality among patients with multisystem trauma.
  The Journal of bone and joint surgery. American volume 2009 Morshed S, Miclau T, Bembom O, Cohen M, Knudson MM, Colford JM
• Qualitative and quantitative assessment of bone fragility and fracture healing using conventional radiography and advanced imaging technologies--focus on wrist fracture.
  Journal of orthopaedic trauma 2008 Firoozabadi R, Morshed S, Engelke K, Prevrhal S, Fierlinger A, Miclau T, Genant HK
• Variability in the assessment of fracture-healing in orthopaedic trauma studies.
  The Journal of bone and joint surgery. American volume 2008 Corrales LA, Morshed S, Bhandari M, Miclau T
• Outcome assessment in clinical trials of fracture-healing.
  The Journal of bone and joint surgery. American volume 2008 Morshed S, Corrales L, Genant H, Miclau T
• What's new in orthopaedic trauma.
  The Journal of bone and joint surgery. American volume 2007 Cole PA, Miclau T, Bhandari M