Thea Mauro, MD
Professor
Dermatology
School of Medicine
Awards
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- Chair, Barrier Function of Mammalian Skin, Gordon Research Conferences, 2011-2013
- Ad Hoc Member, Various Study Sections, NIH, 2010-2021
- Medical Scholar Award, School of Medicine, UCSF, 1987-1988
Education & Training
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- Clin Dir, Plan & Develop SFVA Health Care System 2019
- Serv Chief, Dermatology SFVA Health Care System 2019
- Vice Chair, Assoc Prof, Dermatology UCSF 2019
- Inter Dep Chief of Staff SFVA Health Care System 2018
- Visiting Scientist University of Padova 06/2001
- Inter Serv Chief, Dermatology SFVA Health Care System 06/1999
- Asst Serv Chief, Dermatology SFVA Medical Center 06/1997
- Asst Prof in Res, Dermatology UCSF 06/1997
- Asst Prof in Res, Dermatology UC Davis 06/1992
- Asst Prof, Dermatology UC Davis 06/1991
- Dermatology Instructor Univ of Pennsylvania 06/1989
- Dermatology Residency UC Davis 01/1988
- Physiology Fellowship Univ of Pennsylvania 06/1985
- Internal Medicine Hahnemann Med College 06/1984
- MD Medicine Drexel College of Medicine 06/1983
- AB English Bryn Mawr College 06/1979
- Chief, Mission Bay Derm Lab SFVA Health Care System
- Deputy Chief of Staff SFVA Health Care System
- Professor, Dermatology UCSF
Websites
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- Clinical Profile at UCSF Medical Center (ucsfhealth.org)
- Profile at UCSF Cancer Center (cancer.ucsf.edu)
Grants and Projects
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- Sodium in the Skin and Atopic Dermatitis: The SIS-AD Study, NIH, 2023-2028
- Optimizing Keratinocyte Calcium Signaling Enhances Differentiation in Aged Epidermis, Department of Veterans Affairs, 2023-2027
- The genomic landscape and evolution of cutaneous squamous cell carcinoma, NIH, 2022-2027
- Precision Medicine Approaches to Chronic Inflammatory Skin Disease of Older Veterans, Department of Veterans Affairs, 2023-2027
- Pathogenesis and Therapy of Ichthyosis in Disorders of Lipid Metabolism, NIH, 2012-2024
- Spatial and Temporal Activation in Aged vs. Young Skin, Mt. Zion Health Fund/UCSF, 2022-2024
- Epidermal Skin Barrier and Inflammaging, BAKAR Aging Research Institute (UCSF), 2021-2022
- Full Thickness Skin Models from Human Pluripotent Stem Cells for Identification and Testing Effectiveness of Personalized Therapies in Atopic Dermatitis, Leo Foundation, 2017-2021
- ATP2A2-Regulated Keretinocyted Ca2+ Signaling Mechanisms, NIH, 2004-2020
- Measuring Biomarkers in Skin in Response to Chemical Treatment, Unilever R&D, 2019
- Modeling Lip Barrier Properties, Pfizer Corporation, 2016-2018
- Generation and Characterization of Non-Human Animal Skin Models, VitroLabs, Inc., 2017-2016
- Laboratory for Fluorescence Dynamics, NIH, 1900-2016
- Aging Stratum Corneum pH and Barrier Function, NIH, 2008-2014
- The Lipid and Tight Junction Epidermal Barriers are Interdependent, NIH, 2012-2014
- 2013 Barrier Function of Mammalian Skin Gordon Research Conferences, NIH, 2013-2014
- Barrier Function of Mammalian Skin Gordon Research Conference, NIH, 2011-2012
- Relationship of Keratinocyte Function to Differentiation, NIH, 1988-2010
- Cgmp Channel Isoforms and Keratinocyte Differentiations, NIH, 1997-2003
- Membrane Current Control of Keratinocyte Differentiation, NIH, 1991-1995
Publications (142)
Top publication keywords:
Calcium ChannelsEpidermisCalciumDarier DiseaseReceptors, Calcium-SensingSkin Physiological PhenomenaSarcoplasmic Reticulum Calcium-Transporting ATPasesKeratinocytesPermeabilityPemphigus, Benign FamilialSkin AgingSkinIntermediate Filament ProteinsSodium-Hydrogen ExchangersCalcium Signaling
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Restoring Endoplasmic Reticulum Calcium Stores in Aged Epidermis Improves the Epidermal Calcium Gradient and Enhances FLG Expression.
The Journal of investigative dermatology 2023 Celli A, Pitchford M, Lu N, Mayes AE, Evans RL, Mauro TM -
Link between the skin and autism spectrum disorder.
Frontiers in psychiatry 2023 Man MQ, Yang S, Mauro TM, Zhang G, Zhu T -
Association of Epidermal Biophysical Properties with Obesity and Its Implications.
Skin pharmacology and physiology 2023 Zhu T, Yang S, Mauro TM, Man MQ -
Sodium in the skin: a summary of the physiology and a scoping review of disease associations.
Clinical and experimental dermatology 2023 Chattopadhyay A, Tully J, Shan J, Sheikh S, Ohliger M, Gordon JW, Mauro T, Abuabara K -
Link between obesity and atopic dermatitis: Does obesity predispose to atopic dermatitis, or vice versa?
Experimental dermatology 2023 Yang S, Zhu T, Wakefield JS, Mauro TM, Elias PM, Man MQ
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Skin Barrier Function and Cognition among Older Adults.
The Journal of investigative dermatology 2023 Kim RW, An Y, Zukley L, Ferrucci L, Mauro T, Yaffe K, Resnick SM, Abuabara K -
FLG Deficiency in Mice Alters the Early-Life CD4+ T-Cell Response to Skin Commensal Bacteria.
The Journal of investigative dermatology 2022 Gonzalez JR, Celli A, Weckel A, Dhariwala MO, Merana GR, Ojewumi OT, Okoro J, Dwyer LR, Tran VM, Meyer JM, Mauro TM, Scharschmidt TC -
Skin and bone crosstalk during aging.
Nature aging 2022 Mauro T, Bikle D -
ALOX12B and PNPLA1 Have Distinct Roles in Epidermal Lipid Lamellar Organization.
The Journal of investigative dermatology 2022 Meyer JM, Vávrová K, Radner FPW, Schneider H, Dick A, Mauro TM, Elias PM -
Alterations in epidermal function in type 2 diabetes: Implications for the management of this disease.
Journal of diabetes 2022 Man MQ, Wakefield JS, Mauro TM, Elias PM -
The link between cutaneous inflammation and cognitive impairment.
Journal of the European Academy of Dermatology and Venereology : JEADV 2022 Wen S, Elias PM, Wakefield JS, Mauro TM, Man MQ -
Classification of human chronic inflammatory skin disease based on single-cell immune profiling.
Science immunology 2022 Liu Y, Wang H, Taylor M, Cook C, Martínez-Berdeja A, North JP, Harirchian P, Hailer AA, Zhao Z, Ghadially R, Ricardo-Gonzalez RR, Grekin RC, Mauro TM, Kim E, Choi J, Purdom E, Cho RJ, Cheng JB -
Regulatory Role of Nitric Oxide in Cutaneous Inflammation.
Inflammation 2022 Man MQ, Wakefield JS, Mauro TM, Elias PM -
Epidermal Basement Membrane Substitutes for Bioengineering of Human Epidermal Equivalents.
JID innovations : skin science from molecules to population health 2021 Kolundzic N, Khurana P, Crumrine D, Celli A, Mauro TM, Ilic D -
Role of nitric oxide in regulating epidermal permeability barrier function.
Experimental dermatology 2021 Man MQ, Wakefield JS, Mauro TM, Elias PM -
Ode to Salt: Commentary on "Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity".
The Journal of investigative dermatology 2021 Mauro TM -
Decreased Calcium-Sensing Receptor Expression Controls Calcium Signaling and Cell-To-Cell Adhesion Defects in Aged Skin.
The Journal of investigative dermatology 2021 Celli A, Tu CL, Lee E, Bikle DD, Mauro TM -
Unbound Corneocyte Lipid Envelopes in 12R-Lipoxygenase Deficiency Support a Specific Role in Lipid-Protein Cross-Linking.
The American journal of pathology 2021 Meyer JM, Crumrine D, Schneider H, Dick A, Schmuth M, Gruber R, Radner FPW, Grond S, Wakefield JS, Mauro TM, Elias PM -
CERKL is upregulated in cutaneous squamous cell carcinoma and maintains cellular sphingolipids and resistance to oxidative stress.
The British journal of dermatology 2021 Meyer JM, Lee E, Celli A, Park K, Cho R, Lambert W, Pitchford M, Gordon M, Tsai K, Cleaver J, Arron ST, Mauro TM -
CERKL is Upregulated in Cutaneous Squamous Cell Carcinoma and Maintains Cellular Sphingolipids and Resistance to Oxidative Stress.
The British journal of dermatology 2020 Meyer JM, Lee E, Celli A, Park K, Cho R, Lambert W, Pitchford M, Gordon M, Tsai K, Cleaver J, Arron ST, Mauro TM -
Mutations in 3β-hydroxysteroid-δ8, δ7-isomerase paradoxically benefit epidermal permeability barrier homeostasis in mice.
Experimental dermatology 2020 Dang E, Man G, Lee D, Crumrine DA, Mauro TM, Elias PM, Man MQ -
Markers for Ca++ -induced terminal differentiation of keratinocytes in vitro under defined conditions.
Experimental dermatology 2020 Jeriha J, Kolundzic N, Khurana P, Gordon M, Celli A, Mauro TM, Ilic D -
Inducible nitric oxide synthase is required for epidermal permeability barrier homeostasis in mice.
Experimental dermatology 2020 Dang E, Man G, Zhang J, Lee D, Mauro TM, Elias PM, Man MQ -
Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes.
ACS nano 2020 Huang X, Shi X, Hansen ME, Setiady I, Nemeth CL, Celli A, Huang B, Mauro T, Koval M, Desai TA -
Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation.
iScience 2020 Liu Y, Cook C, Sedgewick AJ, Zhang S, Fassett MS, Ricardo-Gonzalez RR, Harirchian P, Kashem SW, Hanakawa S, Leistico JR, North JP, Taylor MA, Zhang W, Man MQ, Charruyer A, Beliakova-Bethell N, Benz SC… -
Perspective and Consensus Opinion: Good Practices for Using Organotypic Skin and Epidermal Equivalents in Experimental Dermatology Research.
The Journal of investigative dermatology 2020 van den Bogaard E, Ilic D, Dubrac S, Tomic-Canic M, Bouwstra J, Celli A, Mauro T, 2019 Barrier Function of Mammalian Skin Gordon Research Conference, Waterville Valley, New Hampshire -
Aging-associated alterations in epidermal function and their clinical significance.
Aging 2020 Wang Z, Man MQ, Li T, Elias PM, Mauro TM -
Ischemic Fasciitis Mimicking A Lipoma.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2020 Saeed L, Bahrani E, Lauw MIS, Tabatabai ZL, Arron ST, Mauro TM -
Botulinum toxin type A suppresses pro-fibrotic effects via the JNK signaling pathway in hypertrophic scar fibroblasts.
Archives of dermatological research 2019 Park GS, An MK, Yoon JH, Park SS, Koh SH, Mauro TM, Cho EB, Park EJ, Kim KH, Kim KJ -
Induced pluripotent stem cell line heterozygous for p.R501X mutation in filaggrin: KCLi003-A.
Stem cell research 2019 Kolundzic N, Khurana P, Devito L, Jeriha J, Marx J, Hobbs C, Wong XFCC, Common JEA, Liovic M, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D -
The pathological role of Wnt5a in psoriasis and psoriatic arthritis.
Journal of cellular and molecular medicine 2019 Tian F, Mauro TM, Li Z -
Induced pluripotent stem cell line heterozygous for p.R2447X mutation in filaggrin: KCLi002-A.
Stem cell research 2019 Kolundzic N, Khurana P, Devito L, Donne M, Hobbs C, Jeriha J, Wong XFCC, Common JAE, Lane EB, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D -
Topical applications of an emollient reduce circulating pro-inflammatory cytokine levels in chronically aged humans: a pilot clinical study.
Journal of the European Academy of Dermatology and Venereology : JEADV 2019 Ye L, Mauro TM, Dang E, Wang G, Hu LZ, Yu C, Jeong S, Feingold K, Elias PM, Lv CZ, Man MQ -
A20 and ABIN1 Suppression of a Keratinocyte Inflammatory Program with a Shared Single-Cell Expression Signature in Diverse Human Rashes.
The Journal of investigative dermatology 2018 Harirchian P, Lee J, Hilz S, Sedgewick AJ, Perez White BE, Kesling MJ, Mully T, Golovato J, Gray M, Mauro TM, Purdom E, Kim EA, Sbitany H, Bhutani T, Vaske CJ, Benz SC, Cho RJ, Cheng JB -
Mutations in Recessive Congenital Ichthyoses Illuminate the Origin and Functions of the Corneocyte Lipid Envelope.
The Journal of investigative dermatology 2018 Crumrine D, Khnykin D, Krieg P, Man MQ, Celli A, Mauro TM, Wakefield JS, Menon G, Mauldin E, Miner JH, Lin MH, Brash AR, Sprecher E, Radner FPW, Choate K, Roop D, Uchida Y, Gruber R, Schmuth M, Elias … -
Calcium-Sensing Receptor Regulates Epidermal Intracellular Ca2+ Signaling and Re-Epithelialization after Wounding.
The Journal of investigative dermatology 2018 Tu CL, Celli A, Mauro T, Chang W -
Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution.
Cell reports 2018 Cheng JB, Sedgewick AJ, Finnegan AI, Harirchian P, Lee J, Kwon S, Fassett MS, Golovato J, Gray M, Ghadially R, Liao W, Perez White BE, Mauro TM, Mully T, Kim EA, Sbitany H, Neuhaus IM, Grekin RC, Yu … -
A data mining paradigm for identifying key factors in biological processes using gene expression data.
Scientific reports 2018 Li J, Zheng L, Uchiyama A, Bin L, Mauro TM, Elias PM, Pawelczyk T, Sakowicz-Burkiewicz M, Trzeciak M, Leung DYM, Morasso MI, Yu P -
Mohs Micrographic Surgery in the Veterans Health Administration.
Federal practitioner : for the health care professionals of the VA, DoD, and PHS 2018 Tam A, Yuan JT, Mauro TM, Dellavalle RP, Arron ST -
Warfarin-Associated Nonuremic Calciphylaxis.
JAMA dermatology 2017 Yu WY, Bhutani T, Kornik R, Pincus LB, Mauro T, Rosenblum MD, Fox LP -
Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum Inflammatory Cytokines.
The Journal of investigative dermatology 2017 Hu L, Mauro TM, Dang E, Man G, Zhang J, Lee D, Wang G, Feingold KR, Elias PM, Man MQ -
Voriconazole exposure regulates distinct cell-cycle and terminal differentiation pathways in primary human keratinocytes.
The British journal of dermatology 2017 Mansh M, Ing L, Dimon M, Celli A, Mauro TM, Arron ST -
Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin.
Stem cells and development 2016 Petrova A, Capalbo A, Jacquet L, Hazelwood-Smith S, Dafou D, Hobbs C, Arno M, Farcomeni A, Devito L, Badraiq H, Simpson M, McGrath JA, Di WL, Cheng JB, Mauro TM, Ilic D -
Endoplasmic Reticulum Calcium Regulates Epidermal Barrier Response and Desmosomal Structure.
The Journal of investigative dermatology 2016 Celli A, Crumrine D, Meyer JM, Mauro TM -
Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production.
Journal of dermatological science 2015 Jeong SK, Kim YI, Shin KO, Kim BW, Lee SH, Jeon JE, Kim HJ, Lee YM, Mauro TM, Elias PM, Uchida Y, Park K -
Altered epidermal lipid processing and calcium distribution in the KID syndrome mouse model Cx26S17F.
FEBS letters 2015 Bosen F, Celli A, Crumrine D, vom Dorp K, Ebel P, Jastrow H, Dörmann P, Winterhager E, Mauro T, Willecke K -
UVB induces epidermal 11β-hydroxysteroid dehydrogenase type 1 activity in vivo.
Experimental dermatology 2015 Tiganescu A, Hupe M, Jiang YJ, Celli A, Uchida Y, Mauro TM, Bikle DD, Elias PM, Holleran WM -
Nanotopography facilitates in vivo transdermal delivery of high molecular weight therapeutics through an integrin-dependent mechanism.
Nano letters 2015 Walsh L, Ryu J, Bock S, Koval M, Mauro T, Ross R, Desai T -
Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency.
The American journal of pathology 2015 Gruber R, Sugarman JL, Crumrine D, Hupe M, Mauro TM, Mauldin EA, Thyssen JP, Brandner JM, Hennies HC, Schmuth M, Elias PM -
Lowered humidity produces human epidermal equivalents with enhanced barrier properties.
Tissue engineering. Part C, Methods 2015 Sun R, Celli A, Crumrine D, Hupe M, Adame LC, Pennypacker SD, Park K, Uchida Y, Feingold KR, Elias PM, Ilic D, Mauro TM -
Topical hesperidin enhances epidermal function in an aged murine model.
The Journal of investigative dermatology 2014 Man G, Mauro TM, Zhai Y, Kim PL, Cheung C, Hupe M, Crumrine D, Elias PM, Man MQ -
Topical hesperidin prevents glucocorticoid-induced abnormalities in epidermal barrier function in murine skin.
Experimental dermatology 2014 Man G, Mauro TM, Kim PL, Hupe M, Zhai Y, Sun R, Crumrine D, Cheung C, Nuno-Gonzalez A, Elias PM, Man MQ -
Endoplasmic reticulum calcium, stress, and cell-to-cell adhesion.
The Journal of investigative dermatology 2014 Mauro T -
Ibrutinib rash in a patient with 17p del chronic lymphocytic leukemia.
American journal of hematology 2014 Mannis G, Wu D, Dea T, Mauro T, Hsu G -
Calcium, Orai1, and epidermal proliferation.
The Journal of investigative dermatology 2014 Bikle DD, Mauro TM -
3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells.
Stem cell reports 2014 Petrova A, Celli A, Jacquet L, Dafou D, Crumrine D, Hupe M, Arno M, Hobbs C, Cvoro A, Karagiannis P, Devito L, Sun R, Adame LC, Vaughan R, McGrath JA, Mauro TM, Ilic D -
Basis for enhanced barrier function of pigmented skin.
The Journal of investigative dermatology 2014 Man MQ, Lin TK, Santiago JL, Celli A, Zhong L, Huang ZM, Roelandt T, Hupe M, Sundberg JP, Silva KA, Crumrine D, Martin-Ezquerra G, Trullas C, Sun R, Wakefield JS, Wei ML, Feingold KR, Mauro TM, Elias … -
Increased glucocorticoid activation during mouse skin wound healing.
The Journal of endocrinology 2014 Tiganescu A, Hupe M, Uchida Y, Mauro T, Elias PM, Holleran WM -
Comparison of publication trends in dermatology among Japan, South Korea and Mainland China.
BMC dermatology 2014 Man H, Xin S, Bi W, Lv C, Mauro TM, Elias PM, Man MQ -
sPLA2 and the epidermal barrier.
Biochimica et biophysica acta 2013 Ilic D, Bollinger JM, Gelb M, Mauro TM -
Ten-year publication trends in dermatology in mainland China.
International journal of dermatology 2013 Xin S, Mauro JA, Mauro TM, Elias PM, Man MQ -
Local blockade of glucocorticoid activation reverses stress- and glucocorticoid-induced delays in cutaneous wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2013 Youm JK, Park K, Uchida Y, Chan A, Mauro TM, Holleran WM, Elias PM -
Topical apigenin improves epidermal permeability barrier homoeostasis in normal murine skin by divergent mechanisms.
Experimental dermatology 2013 Hou M, Sun R, Hupe M, Kim PL, Park K, Crumrine D, Lin TK, Santiago JL, Mauro TM, Elias PM, Man MQ -
Systemic retinoids in the management of ichthyoses and related skin types.
Dermatologic therapy 2013 Digiovanna JJ, Mauro T, Milstone LM, Schmuth M, Toro JR -
Topical apigenin alleviates cutaneous inflammation in murine models.
Evidence-based complementary and alternative medicine : eCAM 2012 Man MQ, Hupe M, Sun R, Man G, Mauro TM, Elias PM -
Overexpression of calcium-permeable glutamate receptors in glioblastoma derived brain tumor initiating cells.
PloS one 2012 Oh MC, Kim JM, Safaee M, Kaur G, Sun MZ, Kaur R, Celli A, Mauro TM, Parsa AT -
Tight junction properties change during epidermis development.
Experimental dermatology 2012 Celli A, Zhai Y, Jiang YJ, Crumrine D, Elias PM, Feingold KR, Mauro TM -
SERCA2-controlled Ca²+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: a therapeutic target for Darier's disease.
The Journal of investigative dermatology 2012 Celli A, Mackenzie DS, Zhai Y, Tu CL, Bikle DD, Holleran WM, Uchida Y, Mauro TM -
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2011 Wang NJ, Sanborn Z, Arnett KL, Bayston LJ, Liao W, Proby CM, Leigh IM, Collisson EA, Gordon PB, Jakkula L, Pennypacker S, Zou Y, Sharma M, North JP, Vemula SS, Mauro TM, Neuhaus IM, Leboit PE, Hur JS,… -
Regulation of cathelicidin antimicrobial peptide expression by an endoplasmic reticulum (ER) stress signaling, vitamin D receptor-independent pathway.
The Journal of biological chemistry 2011 Park K, Elias PM, Oda Y, Mackenzie D, Mauro T, Holleran WM, Uchida Y -
Temporal dissection of tumorigenesis in primary cancers.
Cancer discovery 2011 Durinck S, Ho C, Wang NJ, Liao W, Jakkula LR, Collisson EA, Pons J, Chan SW, Lam ET, Chu C, Park K, Hong SW, Hur JS, Huh N, Neuhaus IM, Yu SS, Grekin RC, Mauro TM, Cleaver JE, Kwok PY, LeBoit PE, Getz… -
Acidification in the epidermis and the role of secretory phospholipases.
Dermato-endocrinology 2011 Chan A, Mauro T -
A topical Chinese herbal mixture improves epidermal permeability barrier function in normal murine skin.
Experimental dermatology 2011 Man M, Hupe M, Mackenzie D, Kim H, Oda Y, Crumrine D, Lee SH, Martin-Ezquerra G, Trullas C, Mauro TM, Feingold KR, Elias PM, Man MQ -
Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis.
Archives of dermatological research 2010 Behne MJ, Sanchez S, Barry NP, Kirschner N, Meyer W, Mauro TM, Moll I, Gratton E -
Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis.
The British journal of dermatology 2010 Celli A, Mackenzie DS, Crumrine DS, Tu CL, Hupe M, Bikle DD, Elias PM, Mauro TM -
Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification?
The Journal of investigative dermatology 2010 Fluhr JW, Elias PM, Man MQ, Hupe M, Selden C, Sundberg JP, Tschachler E, Eckhart L, Mauro TM, Feingold KR -
The epidermal Ca(2+) gradient: Measurement using the phasor representation of fluorescent lifetime imaging.
Biophysical journal 2010 Celli A, Sanchez S, Behne M, Hazlett T, Gratton E, Mauro T -
Epidermal barrier dysfunction in non-atopic HIV: evidence for an "inside-to-outside" pathogenesis.
The Journal of investigative dermatology 2009 Gunathilake R, Schmuth M, Scharschmidt TC, Gruber R, Grabher D, Leslie KS, Maurer TA, Mauro TM, Elias PM -
Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators.
The Journal of allergy and clinical immunology 2009 Hatano Y, Man MQ, Uchida Y, Crumrine D, Mauro TM, Feingold KR, Elias PM, Holleran WM -
Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes.
The Journal of investigative dermatology 2009 Hachem JP, Roelandt T, Schürer N, Pu X, Fluhr J, Giddelo C, Man MQ, Crumrine D, Roseeuw D, Feingold KR, Mauro T, Elias PM -
Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.
The Journal of allergy and clinical immunology 2009 Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM -
Akt2 and SGK3 are both determinants of postnatal hair follicle development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 Mauro TM, McCormick JA, Wang J, Boini KM, Ray L, Monks B, Birnbaum MJ, Lang F, Pearce D -
Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.
The Journal of investigative dermatology 2009 Hatano Y, Man MQ, Uchida Y, Crumrine D, Scharschmidt TC, Kim EG, Mauro TM, Feingold KR, Elias PM, Holleran WM -
pH-regulated mechanisms account for pigment-type differences in epidermal barrier function.
The Journal of investigative dermatology 2009 Gunathilake R, Schurer NY, Shoo BA, Celli A, Hachem JP, Crumrine D, Sirimanna G, Feingold KR, Mauro TM, Elias PM -
Topical peroxisome proliferator activated receptor activators accelerate postnatal stratum corneum acidification.
The Journal of investigative dermatology 2008 Fluhr JW, Man MQ, Hachem JP, Crumrine D, Mauro TM, Elias PM, Feingold KR -
Acute modulations in permeability barrier function regulate epidermal cornification: role of caspase-14 and the protease-activated receptor type 2.
The American journal of pathology 2007 Demerjian M, Hachem JP, Tschachler E, Denecker G, Declercq W, Vandenabeele P, Mauro T, Hupe M, Crumrine D, Roelandt T, Houben E, Elias PM, Feingold KR -
Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice.
The Journal of clinical investigation 2007 Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, Elias PM -
Stratum corneum acidification is impaired in moderately aged human and murine skin.
The Journal of investigative dermatology 2007 Choi EH, Man MQ, Xu P, Xin S, Liu Z, Crumrine DA, Jiang YJ, Fluhr JW, Feingold KR, Elias PM, Mauro TM -
Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization.
The American journal of pathology 2007 Ilic D, Mao-Qiang M, Crumrine D, Dolganov G, Larocque N, Xu P, Demerjian M, Brown BE, Lim ST, Ossovskaya V, Schlaepfer DD, Fisher SJ, Feingold KR, Elias PM, Mauro TM -
CaR talk: the calcium receptor finds new places to park.
The Journal of investigative dermatology 2007 Mauro TM -
Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation.
The Journal of investigative dermatology 2007 Aberg KM, Racz E, Behne MJ, Mauro TM -
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007 Bianco SD, Peng JB, Takanaga H, Suzuki Y, Crescenzi A, Kos CH, Zhuang L, Freeman MR, Gouveia CH, Wu J, Luo H, Mauro T, Brown EM, Hediger MA -
Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function.
American journal of physiology. Regulatory, integrative and comparative physiology 2006 Choi EH, Demerjian M, Crumrine D, Brown BE, Mauro T, Elias PM, Feingold KR -
Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome.
The Journal of investigative dermatology 2006 Hachem JP, Wagberg F, Schmuth M, Crumrine D, Lissens W, Jayakumar A, Houben E, Mauro TM, Leonardsson G, Brattsand M, Egelrud T, Roseeuw D, Clayman GL, Feingold KR, Williams ML, Elias PM -
Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model.
Experimental dermatology 2006 Demerjian M, Man MQ, Choi EH, Brown BE, Crumrine D, Chang S, Mauro T, Elias PM, Feingold KR -
Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK.
Oncogene 2006 Essayem S, Kovacic-Milivojevic B, Baumbusch C, McDonagh S, Dolganov G, Howerton K, Larocque N, Mauro T, Ramirez A, Ramos DM, Fisher SJ, Jorcano JL, Beggs HE, Reichardt LF, Ilic D -
Activity of the hSPCA1 Golgi Ca2+ pump is essential for Ca2+-mediated Ca2+ response and cell viability in Darier disease.
Journal of cell science 2006 Foggia L, Aronchik I, Aberg K, Brown B, Hovnanian A, Mauro TM -
Extracellular pH Controls NHE1 expression in epidermis and keratinocytes: implications for barrier repair.
The Journal of investigative dermatology 2005 Hachem JP, Behne M, Aronchik I, Demerjian M, Feingold KR, Elias PM, Mauro TM -
Sarcoidosis associated with pegylated interferon alfa and ribavirin treatment for chronic hepatitis C: a case report and review of the literature.
Archives of dermatology 2005 Hurst EA, Mauro T -
Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy.
AIDS (London, England) 2004 Mafong DD, Lee GA, Yu S, Tien P, Mauro T, Grunfeld C -
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development.
Molecular biology of the cell 2004 McCormick JA, Feng Y, Dawson K, Behne MJ, Yu B, Wang J, Wyatt AW, Henke G, Grahammer F, Mauro TM, Lang F, Pearce D -
Functional consequences of a neutral pH in neonatal rat stratum corneum.
The Journal of investigative dermatology 2004 Fluhr JW, Mao-Qiang M, Brown BE, Hachem JP, Moskowitz DG, Demerjian M, Haftek M, Serre G, Crumrine D, Mauro TM, Elias PM, Feingold KR -
Analysis: blood glucose monitoring: making the possible practical.
Diabetes technology & therapeutics 2004 Mauro T -
Stratum corneum acidification in neonatal skin: secretory phospholipase A2 and the sodium/hydrogen antiporter-1 acidify neonatal rat stratum corneum.
The Journal of investigative dermatology 2004 Fluhr JW, Behne MJ, Brown BE, Moskowitz DG, Selden C, Mao-Qiang M, Mauro TM, Elias PM, Feingold KR -
Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes.
The Journal of investigative dermatology 2003 Aronchik I, Behne MJ, Leypoldt L, Crumrine D, Epstein E, Ikeda S, Mizoguchi M, Bench G, Pozzan T, Mauro T -
Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.
The Journal of investigative dermatology 2003 Behne MJ, Tu CL, Aronchik I, Epstein E, Bench G, Bikle DD, Pozzan T, Mauro TM -
'The discovery channel': CRAC'king the code of calcium influx.
The Journal of investigative dermatology 2003 Mauro T -
Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function.
The Journal of investigative dermatology 2003 Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RW, Gratton E, Feingold K, Holleran WM, Elias PM, Mauro TM -
Defective cyclic guanosine monophosphate-gated calcium channels and the pathogenesis of psoriasis.
Acta dermato-venereologica 2003 McKenzie RC, Oda Y, Szepietowski JC, Behne MJ, Mauro T -
NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging.
The Journal of biological chemistry 2002 Behne MJ, Meyer JW, Hanson KM, Barry NP, Murata S, Crumrine D, Clegg RW, Gratton E, Holleran WM, Elias PM, Mauro TM -
Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation.
Journal of cellular physiology 2002 Komuves L, Oda Y, Tu CL, Chang WH, Ho-Pao CL, Mauro T, Bikle DD -
The ENaC channel is required for normal epidermal differentiation.
The Journal of investigative dermatology 2002 Mauro T, Guitard M, Behne M, Oda Y, Crumrine D, Komuves L, Rassner U, Elias PM, Hummler E -
Treatment of an ulcerated hemangioma with recombinant platelet-derived growth factor.
Archives of dermatology 2002 Sugarman JL, Mauro TM, Frieden IJ -
Changes in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiation.
Developmental dynamics : an official publication of the American Association of Anatomists 2000 Kömüves LG, Shen WF, Kwong A, Stelnicki E, Rozenfeld S, Oda Y, Blink A, Krishnan K, Lau B, Mauro T, Largman C -
The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation.
The Journal of biological chemistry 2000 Oda Y, Tu CL, Chang W, Crumrine D, Kömüves L, Mauro T, Elias PM, Bikle DD -
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.
Nature genetics 2000 Hu Z, Bonifas JM, Beech J, Bench G, Shigihara T, Ogawa H, Ikeda S, Mauro T, Epstein EH -
Epithelial sodium channels are upregulated during epidermal differentiation.
The Journal of investigative dermatology 1999 Oda Y, Imanzahrai A, Kwong A, Kömüves L, Elias PM, Largman C, Mauro T -
Acute barrier perturbation abolishes the Ca2+ and K+ gradients in murine epidermis: quantitative measurement using PIXE.
The Journal of investigative dermatology 1998 Mauro T, Bench G, Sidderas-Haddad E, Feingold K, Elias P, Cullander C -
The secretory granular cell: the outermost granular cell as a specialized secretory cell.
The journal of investigative dermatology. Symposium proceedings 1998 Elias PM, Cullander C, Mauro T, Rassner U, Kömüves L, Brown BE, Menon GK -
Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing.
Archives of dermatological research 1998 Mauro T, Holleran WM, Grayson S, Gao WN, Man MQ, Kriehuber E, Behne M, Feingold KR, Elias PM -
Formation of the epidermal calcium gradient coincides with key milestones of barrier ontogenesis in the rodent.
The Journal of investigative dermatology 1998 Elias PM, Nau P, Hanley K, Cullander C, Crumrine D, Bench G, Sideras-Haddad E, Mauro T, Williams ML, Feingold KR -
Alternatively spliced forms of the cGMP-gated channel in human keratinocytes.
FEBS letters 1997 Oda Y, Timpe LC, McKenzie RC, Sauder DN, Largman C, Mauro T -
Keratinocyte K+ channels mediate Ca2+-induced differentiation.
The Journal of investigative dermatology 1997 Mauro T, Dixon DB, Komuves L, Hanley K, Pappone PA -
Calcium and potassium inhibit barrier recovery after disruption, independent of the type of insult in hairless mice.
Experimental dermatology 1997 Mao-Qiang M, Mauro T, Bench G, Warren R, Elias PM, Feingold KR -
Activation of keratinocyte nicotinic cholinergic receptors stimulates calcium influx and enhances cell differentiation.
The Journal of investigative dermatology 1996 Grando SA, Horton RM, Mauro TM, Kist DA, Lee TX, Dahl MV -
Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor.
The Journal of clinical investigation 1996 Bikle DD, Ratnam A, Mauro T, Harris J, Pillai S -
Disseminated cutaneous Cryptococcus clinically mimicking basal cell carcinoma.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 1995 Murakawa GJ, Mauro TM, Egbert B -
Treatment of leg ulcers with cultured epithelial autografts: clinical study and case reports.
Ostomy/wound management 1995 Límová M, Mauro T -
Amiloride blocks a keratinocyte nonspecific cation channel and inhibits Ca(++)-induced keratinocyte differentiation.
The Journal of investigative dermatology 1995 Mauro T, Dixon DB, Hanley K, Isseroff RR, Pappone PA -
Treatment of pyoderma gangrenosum with cultured keratinocyte autografts.
The Journal of dermatologic surgery and oncology 1994 Límová M, Mauro T -
A role for ions in barrier recovery after acute perturbation.
The Journal of investigative dermatology 1994 Lee SH, Elias PM, Feingold KR, Mauro T -
Mal de Meleda in a Laotian family.
International journal of dermatology 1993 Chotzen VA, Starr JC, Mauro TM -
Ion channels are linked to differentiation in keratinocytes.
The Journal of membrane biology 1993 Mauro TM, Isseroff RR, Lasarow R, Pappone PA -
Acrodermatitis enteropathica in a patient with the acquired immunodeficiency syndrome.
Archives of dermatology 1992 Reichel M, Mauro TM, Ziboh VA, Huntley AC, Fletcher MP -
Autologous skin grafts for leg ulcers.
The Western journal of medicine 1992 Mauro TM -
Urticaria and hepatitis C.
Lancet (London, England) 1990 Reichel M, Mauro TM -
Extracellular calcium affects the membrane currents of cultured human keratinocytes.
Journal of cellular physiology 1990 Mauro TM, Pappone PA, Isseroff RR -
Establishment of a human cutaneous T-cell lymphoma in C.B-17 SCID mice.
The Journal of investigative dermatology 1990 Charley MR, Tharp M, Locker J, Deng JS, Goslen JB, Mauro T, McCoy P, Abell E, Jegasothy B -
Linear granuloma annulare.
Journal of the American Academy of Dermatology 1989 Harpster EF, Mauro T, Barr RJ -
Effects of TPA on short-circuit current across frog skin.
The American journal of physiology 1987 Mauro T, O'Brien TG, Civan MM -
Effects of tumor promoters on sodium ion transport across frog skin.
The American journal of physiology 1985 Civan MM, Rubenstein D, Mauro T, O'Brien TG -
Postcapillary pH disequilibrium after gas exchange in isolated perfused liver.
Journal of applied physiology: respiratory, environmental and exercise physiology 1979 O'Brasky JE, Mauro T, Crandall ED