Tao Li, PhD
Specialist
Pediatrics
School of Medicine

Publications (11)

Top publication keywords:
Long-Term Synaptic DepressionDrosophilaReceptors, G-Protein-CoupledPhosphatidylserinesMembrane ProteinsSynaptosomesN-Ethylmaleimide-Sensitive ProteinsLimoninsAlternative SplicingNeuronsCell Adhesion Molecules, NeuronalSynapsesVesicular Glutamate Transport Protein 2Drosophila ProteinsMicroglia

• A cross-species proteomic map reveals neoteny of human synapse development.
  Nature 2023 Wang L, Pang K, Zhou L, Cebrián-Silla A, González-Granero S, Wang S, Bi Q, White ML, Ho B, Li J, Li T, Perez Y, Huang EJ, Winkler EA, Paredes MF, Kovner R, Sestan N, Pollen AA, Liu P, Li J, Piao X, …
• GPR56 S4 variant is required for microglia-mediated synaptic pruning.
  Glia 2022 Li T, Luo R, Schmidt R, D'Alessandro N, Kishore P, Zhu B, Yu D, Piao X
• Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits.
  Science advances 2022 Yu D, Li T, Delpech JC, Zhu B, Kishore P, Koshi T, Luo R, Pratt KJB, Popova G, Nowakowski TJ, Villeda SA, Piao X
• Phospholipid-flippase chaperone CDC50A is required for synapse maintenance by regulating phosphatidylserine exposure.
  The EMBO journal 2021 Li T, Yu D, Oak HC, Zhu B, Wang L, Jiang X, Molday RS, Kriegstein A, Piao X
• Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids.
  Cell stem cell 2021 Popova G, Soliman SS, Kim CN, Keefe MG, Hennick KM, Jain S, Li T, Tejera D, Shin D, Chhun BB, McGinnis CS, Speir M, Gartner ZJ, Mehta SB, Haeussler M, Hengen KB, Ransohoff RR, Piao X, Nowakowski TJ

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• A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding.
  The EMBO journal 2020 Li T, Chiou B, Gilman CK, Luo R, Koshi T, Yu D, Oak HC, Giera S, Johnson-Venkatesh E, Muthukumar AK, Stevens B, Umemori H, Piao X
• GAIN domain-mediated cleavage is required for activation of G protein-coupled receptor 56 (GPR56) by its natural ligands and a small-molecule agonist.
  The Journal of biological chemistry 2019 Zhu B, Luo R, Jin P, Li T, Oak HC, Giera S, Monk KR, Lak P, Shoichet BK, Piao X
• Adhesion G Protein-Coupled Receptors as Drug Targets for Neurological Diseases.
  Trends in pharmacological sciences 2019 Folts CJ, Giera S, Li T, Piao X
• Neurexin Restricts Axonal Branching in Columns by Promoting Ephrin Clustering.
  Developmental cell 2017 Liu L, Tian Y, Zhang XY, Zhang X, Li T, Xie W, Han J
• The Neurexin/N-Ethylmaleimide-sensitive Factor (NSF) Interaction Regulates Short Term Synaptic Depression.
  The Journal of biological chemistry 2015 Li T, Tian Y, Li Q, Chen H, Lv H, Xie W, Han J
• Neurexin regulates visual function via mediating retinoid transport to promote rhodopsin maturation.
  Neuron 2013 Tian Y, Li T, Sun M, Wan D, Li Q, Li P, Zhang ZC, Han J, Xie W