Tamara Alliston, PhD
Professor
Orthopaedic Surgery
School of Medicine

In particular, we study the mechanobiology of TGFβ in the skeleton. To answer these questions we combine molecular, cellular, physiologic, bioengineering, and materials science approaches. This interdisciplinary approach will advance the development of therapies that can prevent skeletal disease and improve the speed and success of skeletal tissue regeneration.

• Spatial control of perilacunar canalicular remodeling during lactation.
  Scientific reports 2024 Sieverts M, Yee C, Nemani M, Parkinson DY, Alliston T, Acevedo C
• Effect of Passaging on Bovine Chondrocyte Gene Expression and Engineered Cartilage Production.
  Tissue engineering. Part A 2024 Lindberg ED, Kaya S, Jamali AA, Alliston T, O'Connell GD
• Aging impairs the osteocytic regulation of collagen integrity and bone quality.
  Bone research 2024 Schurman CA, Kaya S, Dole N, Luna NMM, Castillo N, Potter R, Rose JP, Bons J, King CD, Burton JB, Schilling B, Melov S, Tang S, Schaible E, Alliston T
• Abstract C036: Restoration of T effector cells function by targeting senescent cancer-associated fibroblast in tumor microenvironment of stroma-rich cancers.
  Cancer Research 2024 Yao Wang, Hara Apostolopoulou, Arjun Sanyal, Hong Sun, Cynthia Sieland, Kavya Gupta, Jiayu Ye, David Gibbs, Paul Wong, Ntranos Vasilis, Sui Huang, James Gardner, Ajay Maker, Thea Tlsty, Anil Bhushan, …
• Priming chondrocytes during expansion alters cell behavior and improves matrix production in 3D culture.
  Osteoarthritis and cartilage 2023 Lindberg ED, Wu T, Cotner KL, Glazer A, Jamali AA, Sohn LL, Alliston T, O'Connell GD
• Deep learning models to map osteocyte networks can successfully distinguish between young and aged bone.
  bioRxiv : the preprint server for biology 2023 Vetter SD, Schurman CA, Alliston T, Slabaugh GG, Verbruggen SW
• Type 2 diabetes impairs annulus fibrosus fiber deformation and rotation under disc compression in the University of California Davis type 2 diabetes mellitus (UCD-T2DM) rat model.
  PNAS nexus 2023 Rosenberg JL, Schaible E, Bostrom A, Lazar AA, Graham JL, Stanhope KL, Ritchie RO, Alliston TN, Lotz JC, Havel PJ, Acevedo C, Fields AJ
• Genetic and Gene Expression Resources for Osteoporosis and Bone Biology Research.
  Current osteoporosis reports 2023 Kaya S, Alliston T, Evans DS
• Deep coverage and quantification of the bone proteome provides enhanced opportunities for new discoveries in skeletal biology and disease.
  PloS one 2023 Rose JP, Schurman CA, King CD, Bons J, Patel SK, Burton JB, O'Broin A, Alliston T, Schilling B
• Senescence and Inflammation: Summary of a Gerontological Society of America and National Institute on Aging-Sponsored Symposium.
  The journals of gerontology. Series A, Biological sciences and medical sciences 2023 Zhang X, Tyrrell DJ, Alliston T, Schilling B, Yousefzadeh MJ, Schafer MJ
• miR181a/b-1 controls osteocyte metabolism and mechanical properties independently of bone morphology.
  Bone 2023 Yoon J, Kaya S, Matsumae G, Dole N, Alliston T
• The Multifaceted Effects of Osteocytic TGFβ Signaling on the Skeletal and Extraskeletal Functions of Bone.
  Current osteoporosis reports 2023 Carroll M, Alliston T, Dole N
• Zoledronic acid improves bone quality and muscle function in a high bone turnover state.
  bioRxiv : the preprint server for biology 2023 Trivedi T, Manaa M, John S, Reiken S, Murthy S, Pagnotti GM, Dole NS, She Y, Suresh S, Hain BA, Regan J, Ofer R, Wright L, Robling A, Cao X, Alliston T, Marks AR, Waning DL, Mohammad KS, Guise TA
• Molecular and Cellular Crosstalk between Bone and Brain: Accessing Bidirectional Neural and Musculoskeletal Signaling during Aging and Disease.
  Journal of bone metabolism 2023 Schurman CA, Burton JB, Rose J, Ellerby LM, Alliston T, Schilling B
• Bone-cartilage crosstalk informed by aging mouse bone transcriptomics and human osteoarthritis genome-wide association studies.
  Bone reports 2022 Kaya S, Bailey KN, Schurman CA, Evans DS, Alliston T
• Osteocyte Control of Bone Quality and Fragility in Skeletal Aging.
  The FASEB Journal 2022 Tamara Alliston
• At the Crux of Joint Crosstalk: TGFβ Signaling in the Synovial Joint.
  Current rheumatology reports 2022 Bailey KN, Alliston T
• Prioritization of Genes Relevant to Bone Fragility Through the Unbiased Integration of Aging Mouse Bone Transcriptomics and Human GWAS Analyses.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022 Kaya S, Schurman CA, Dole NS, Evans DS, Alliston T
• Mechanosensitive miR-100 coordinates TGFβ and Wnt signaling in osteocytes during fluid shear stress.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Dole NS, Yoon J, Monteiro DA, Yang J, Mazur CM, Kaya S, Belair CD, Alliston T
• Disrupted osteocyte connectivity and pericellular fluid flow in bone with aging and defective TGF-β signaling.
  Proceedings of the National Academy of Sciences of the United States of America 2021 Schurman CA, Verbruggen SW, Alliston T
• Altered canalicular remodeling associated with femur fracture in mice.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2021 Emami AJ, Sebastian A, Lin YY, Yee CS, Osipov B, Loots GG, Alliston T, Christiansen BA
• Osteocyte-Specific TGFß Signaling Mitigates Obesity-Induced Deregulated Energy Metabolism and Compromised Bone Quality.
  Journal of the Endocrine Society 2021 Neha S Dole, Cristal Yee, Tamara Alliston
• Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Monteiro DA, Dole NS, Campos JL, Kaya S, Schurman CA, Belair CD, Alliston T
• Mechanosensitive Control of Articular Cartilage and Subchondral Bone Homeostasis in Mice Requires Osteocytic Transforming Growth Factor β Signaling.
  Arthritis & rheumatology (Hoboken, N.J.) 2021 Bailey KN, Nguyen J, Yee CS, Dole NS, Dang A, Alliston T
• Assessment of Osteocytes: Techniques for Studying Morphological and Molecular Changes Associated with Perilacunar/Canalicular Remodeling of the Bone Matrix.
  Methods in molecular biology (Clifton, N.J.) 2021 Dole NS, Yee CS, Schurman CA, Dallas SL, Alliston T
• A comparison of alendronate to varying magnitude PEMF in mitigating bone loss and altering bone remodeling in skeletally mature osteoporotic rats.
  Bone 2020 Androjna C, Yee CS, White CR, Waldorff EI, Ryaby JT, Zborowski M, Alliston T, Midura RJ
• Quantitative and qualitative bone imaging: A review of synchrotron radiation microtomography analysis in bone research.
  Journal of the mechanical behavior of biomedical materials 2020 Obata Y, Bale HA, Barnard HS, Parkinson DY, Alliston T, Acevedo C
• TGFβ Regulation of Perilacunar/Canalicular Remodeling Is Sexually Dimorphic.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2020 Dole NS, Yee CS, Mazur CM, Acevedo C, Alliston T
• OR29-04 TGFß Regulates Bone Perilacunar/Canalicular Remodeling in a Sexually Dimorphic Manner.
  Journal of the Endocrine Society 2020 Neha Dole, Tamara Alliston
• The importance of diversity, equity, and inclusion in orthopedic research.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Alliston T, Foucher KC, Frederick B, Hernandez CJ, Iatridis JC, Kozloff KM, Lewis KJ, Liu XS, Mercer DM, Ochia R, Queen RM, Rimnac CM, van der Meulen MCH, Westendorf JJ
• Cartilage/Bone Crosstalk in Joint Health and Disease.
  Osteoarthritis and Cartilage 2020 T. Alliston
• Biologically Regulated Marrow Stimulation by Blocking TGF-β1 With Losartan Oral Administration Results in Hyaline-like Cartilage Repair: A Rabbit Osteochondral Defect Model.
  The American journal of sports medicine 2020 Utsunomiya H, Gao X, Deng Z, Cheng H, Nakama G, Scibetta AC, Ravuri SK, Goldman JL, Lowe WR, Rodkey WG, Alliston T, Philippon MJ, Huard J
• CYLD, a mechanosensitive deubiquitinase, regulates TGFβ signaling in load-induced bone formation.
  Bone 2019 Nguyen J, Massoumi R, Alliston T
• Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis.
  Bone research 2019 Mazur CM, Woo JJ, Yee CS, Fields AJ, Acevedo C, Bailey KN, Kaya S, Fowler TW, Lotz JC, Dang A, Kuo AC, Vail TP, Alliston T
• Investigating Osteocytic Perilacunar/Canalicular Remodeling.
  Current osteoporosis reports 2019 Yee CS, Schurman CA, White CR, Alliston T
• Improvement of Cartilage Repair With Biologically Regulated Marrow Stimulation by Blocking TGF-ß1 in A Rabbit Osteochondral Defect Model.
  Orthopaedic Journal of Sports Medicine 2019 Hajime Utsunomiya, Xueqin Gao, Zhenhan Deng, Haizi Cheng, Alex Scibetta, Sudheer Ravuri, Walter R. Lowe, Marc J. Philippon, Tamara Alliston, Johnny Huard
• Bone Quality Sleuths: Uncovering Tissue-Level Mechanisms of Bone Fragility in Human Type 2 Diabetes.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2019 Alliston T, Schafer A
• Chronic kidney disease and aging differentially diminish bone material and microarchitecture in C57Bl/6 mice.
  Bone 2019 Heveran CM, Schurman CA, Acevedo C, Livingston EW, Howe D, Schaible EG, Hunt HB, Rauff A, Donnelly E, Carpenter RD, Levi M, Lau AG, Bateman TA, Alliston T, King KB, Ferguson VL
• T1ρ-based fibril-reinforced poroviscoelastic constitutive relation of human articular cartilage using inverse finite element technology.
  Quantitative imaging in medicine and surgery 2019 Wan C, Ge L, Souza RB, Tang SY, Alliston T, Hao Z, Li X
• Glucocorticoids cause mandibular bone fragility and suppress osteocyte perilacunar-canalicular remodeling.
  Bone reports 2018 Alemi AS, Mazur CM, Fowler TW, Woo JJ, Knott PD, Alliston T
• Bone marrow lesions in osteoarthritis: What lies beneath.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2018 Alliston T, Hernandez CJ, Findlay DM, Felson DT, Kennedy OD
• Treatment with anti-Sclerostin antibody to stimulate mandibular bone formation.
  Head & neck 2018 Tamplen M, Fowler T, Markey J, Knott PD, Suva LJ, Alliston T
• Contributions of Material Properties and Structure to Increased Bone Fragility for a Given Bone Mass in the UCD-T2DM Rat Model of Type 2 Diabetes.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2018 Acevedo C, Sylvia M, Schaible E, Graham JL, Stanhope KL, Metz LN, Gludovatz B, Schwartz AV, Ritchie RO, Alliston TN, Havel PJ, Fields AJ
• Fatigue as the missing link between bone fragility and fracture.
  Nature biomedical engineering 2018 Acevedo C, Stadelmann VA, Pioletti DP, Alliston T, Ritchie RO
• A modular approach to creating large engineered cartilage surfaces.
  Journal of biomechanics 2017 Ford AC, Chui WF, Zeng AY, Nandy A, Liebenberg E, Carraro C, Kazakia G, Alliston T, O'Connell GD
• Osteocyte-Intrinsic TGF-β Signaling Regulates Bone Quality through Perilacunar/Canalicular Remodeling.
  Cell reports 2017 Dole NS, Mazur CM, Acevedo C, Lopez JP, Monteiro DA, Fowler TW, Gludovatz B, Walsh F, Regan JN, Messina S, Evans DS, Lang TF, Zhang B, Ritchie RO, Mohammad KS, Alliston T
• Dynamic imaging demonstrates that pulsed electromagnetic fields (PEMF) suppress IL-6 transcription in bovine nucleus pulposus cells.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2017 Tang X, Alliston T, Coughlin D, Miller S, Zhang N, Waldorff EI, Ryaby JT, Lotz JC
• Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis.
  Scientific reports 2017 Fowler TW, Acevedo C, Mazur CM, Hall-Glenn F, Fields AJ, Bale HA, Ritchie RO, Lotz JC, Vail TP, Alliston T
• Smad4 regulates growth plate matrix production and chondrocyte polarity.
  Biology open 2017 Whitaker AT, Berthet E, Cantu A, Laird DJ, Alliston T
• Effects of cell type and configuration on anabolic and catabolic activity in 3D co-culture of mesenchymal stem cells and nucleus pulposus cells.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2016 Ouyang A, Cerchiari AE, Tang X, Liebenberg E, Alliston T, Gartner ZJ, Lotz JC
• Parallel mechanisms suppress cochlear bone remodeling to protect hearing.
  Bone 2016 Jáuregui EJ, Akil O, Acevedo C, Hall-Glenn F, Tsai BS, Bale HA, Liebenberg E, Humphrey MB, Ritchie RO, Lustig LR, Alliston T
• Mechanobiology of TGFβ signaling in the skeleton.
  Matrix biology : journal of the International Society for Matrix Biology 2016 Rys JP, Monteiro DA, Alliston T
• Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension.
  eLife 2015 Rys JP, DuFort CC, Monteiro DA, Baird MA, Oses-Prieto JA, Chand S, Burlingame AL, Davidson MW, Alliston TN
• Correlating high-resolution magic angle spinning NMR spectroscopy and gene analysis in osteoarthritic cartilage.
  NMR in biomedicine 2015 Tufts L, Shet Vishnudas K, Fu E, Kurhanewicz J, Ries M, Alliston T, Li X
• Pulsed Electromagnetic Fields (PEMF) Inhibit Matrix Metalloproteinase-13 Expression in Human Annulus Fibrosus Cells.
  The Spine Journal 2014 Xinyan Tang, Rachel Willardson, Dezba Coughlin, Tamara Alliston, Jeffrey C. Lotz
• Calluses flex their muscles to align bone fragments during fracture repair.
  Developmental cell 2014 Nguyen J, Alliston T
• Biological regulation of bone quality.
  Current osteoporosis reports 2014 Alliston T
• How tough is brittle bone? Investigating osteogenesis imperfecta in mouse bone.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 Carriero A, Zimmermann EA, Paluszny A, Tang SY, Bale H, Busse B, Alliston T, Kazakia G, Ritchie RO, Shefelbine SJ
• Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia.
  PloS one 2014 Akil O, Hall-Glenn F, Chang J, Li A, Chang W, Lustig LR, Alliston T, Hsiao EC
• Ligand-independent and tissue-selective androgen receptor inhibition by pyrvinium.
  ACS chemical biology 2014 Lim M, Otto-Duessel M, He M, Su L, Nguyen D, Chin E, Alliston T, Jones JO
• Evolution of a developmental mechanism: Species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis.
  Developmental biology 2013 Hall J, Jheon AH, Ealba EL, Eames BF, Butcher KD, Mak SS, Ladher R, Alliston T, Schneider RA
• Development of a porous poly(DL-lactic acid-co-glycolic acid)-based scaffold for mastoid air-cell regeneration.
  The Laryngoscope 2013 Gould TW, Birchall JP, Mallick AS, Alliston T, Lustig LR, Shakesheff KM, Rahman CV
• Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2013 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M
• Accumulation of exogenous activated TGF-β in the superficial zone of articular cartilage.
  Biophysical journal 2013 Albro MB, Nims RJ, Cigan AD, Yeroushalmi KJ, Alliston T, Hung CT, Ateshian GA
• Regulation of postnatal bone homeostasis by TGFβ.
  BoneKEy reports 2013 Tang SY, Alliston T
• Load regulates bone formation and Sclerostin expression through a TGFβ-dependent mechanism.
  PloS one 2013 Nguyen J, Tang SY, Nguyen D, Alliston T
• Prolonged alendronate treatment prevents the decline in serum TGF-β1 levels and reduces cortical bone strength in long-term estrogen deficiency rat model.
  Bone 2012 Jia J, Yao W, Amugongo S, Shahnazari M, Dai W, Lay YA, Olvera D, Zimmermann EA, Ritchie RO, Li CS, Alliston T, Lane NE
• Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis.
  Arthritis and rheumatism 2012 Chen CG, Thuillier D, Chin EN, Alliston T
• Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance.
  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012 Tang SY, Herber RP, Ho SP, Alliston T
• Smad3 Modulates Tendon Gene Expression and Interacts with Key Tendon Transcription Factors Not a clinical study.
  The Journal Of Hand Surgery 2012 Mohana Amirtharajah, Ellora Berthet, Carol Chen, Tamara Alliston
• ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiation.
  Molecular biology of the cell 2012 Allen JL, Cooke ME, Alliston T
• 150 QUANTITATIVE AND HISTOPATHOLOGICAL ANALYSIS OF OSTEO-ARTHRITIC CARTILAGE USING MRI, HRMAS SPECTROSCOPY AND IMMUNO-HISTOCHEMISTRY.
  Osteoarthritis and Cartilage 2011 K. Shet, F. Liang, T. Alliston, H. Yoshihara, J. Kurhanewicz, M. Ries, A. Horvai, X. Li
• Characterization of the effects of x-ray irradiation on the hierarchical structure and mechanical properties of human cortical bone.
  Biomaterials 2011 Barth HD, Zimmermann EA, Schaible E, Tang SY, Alliston T, Ritchie RO
• Age-related changes in the plasticity and toughness of human cortical bone at multiple length scales.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Zimmermann EA, Schaible E, Bale H, Barth HD, Tang SY, Reichert P, Busse B, Alliston T, Ager JW, Ritchie RO
• TGFß and Runx2 calibration of bone extracellular matrix quality for tissue-specific function.
  BoneKEy Reports 2011 Tamara Alliston, Jolie Chang
• Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy.
  Osteoarthritis and cartilage 2011 Cooke ME, Allon AA, Cheng T, Kuo AC, Kim HT, Vail TP, Marcucio RS, Schneider RA, Lotz JC, Alliston T
• Local tissue properties of human osteoarthritic cartilage correlate with magnetic resonance T(1) rho relaxation times.
  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2011 Tang SY, Souza RB, Ries M, Hansma PK, Alliston T, Li X
• The use of polyacrylamide gels for mechanical calibration of cartilage--a combined nanoindentation and unconfined compression study.
  Journal of the mechanical behavior of biomedical materials 2011 Li C, Allen J, Alliston T, Pruitt LA
• Examination of Bone Ossification Markers in Cochlear Development.
  The Laryngoscope 2011 Jolie Chang, Kristin Butcher, Omar Akil, Rich Schneider, Lawrence Lustig, Tamara Alliston
• Changes in cortical bone response to high-fat diet from adolescence to adulthood in mice.
  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2010 Ionova-Martin SS, Wade JM, Tang S, Shahnazari M, Ager JW, Lane NE, Yao W, Alliston T, Vaisse C, Ritchie RO
• Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-β and Runx2 in bone is required for hearing.
  EMBO reports 2010 Chang JL, Brauer DS, Johnson J, Chen CG, Akil O, Balooch G, Humphrey MB, Chin EN, Porter AE, Butcher K, Ritchie RO, Schneider RA, Lalwani A, Derynck R, Marshall GW, Marshall SJ, Lustig L, Alliston T
• In situ Materials Characterization using the Tissue Diagnostic Instrument.
  Polymer testing 2010 Tang SY, Mathews P, Randall C, Yurtsev E, Fields K, Wong A, Kuo A, Alliston T, Hansma P
• Osteopontin deficiency increases bone fragility but preserves bone mass.
  Bone 2010 Thurner PJ, Chen CG, Ionova-Martin S, Sun L, Harman A, Porter A, Ager JW, Ritchie RO, Alliston T
• Chondroitin sulfate and growth factor signaling in the skeleton: Possible links to MPS VI.
  Journal of pediatric rehabilitation medicine 2010 Alliston T
• Tissue Interactions in Long Bone Development.
  Bone and Development 2010 Céline Colnot, Tamara Alliston
• Reduced size-independent mechanical properties of cortical bone in high-fat diet-induced obesity.
  Bone 2009 Ionova-Martin SS, Do SH, Barth HD, Szadkowska M, Porter AE, Ager JW, Ager JW, Alliston T, Vaisse C, Ritchie RO
• TGF-beta and bone matrix material properties.
  Bone 2009 T. Alliston
• The tissue diagnostic instrument.
  The Review of scientific instruments 2009 Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, Mellbovsky L, Peña MJ, Diez-Ferrer O, Mathews P, …
• A tense situation: forcing tumour progression.
  Nature reviews. Cancer 2009 Butcher DT, Alliston T, Weaver VM
• Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.
  PloS one 2008 Mohammad KS, Chen CG, Balooch G, Stebbins E, McKenna CR, Davis H, Niewolna M, Peng XH, Nguyen DH, Ionova-Martin SS, Bracey JW, Hogue WR, Wong DH, Ritchie RO, Suva LJ, Derynck R, Guise TA, Alliston T
• Chapter 53 Transforming Growth Factor-ß.
  Principles of Bone Biology 2008 Sarah L. Dallas, Tamara Alliston, Lynda F. Bonewald
• Elevated TGF-beta2 signaling in dentin results in sex related enamel defects.
  Archives of oral biology 2007 Saeki K, Hilton JF, Alliston T, Habelitz S, Marshall SJ, Marshall GW, Denbesten P
• TGF-beta regulation of osteoblast differentiation and bone matrix properties.
  Journal of musculoskeletal & neuronal interactions 2006 Alliston T
• Smads In Mesenchymal Differentiation.
  Smad Signal Transduction 2006 Rik Derynck, Lisa Choy, Tamara Alliston
• TGF-beta regulates the mechanical properties and composition of bone matrix.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Balooch G, Balooch M, Nalla RK, Schilling S, Filvaroff EH, Marshall GW, Marshall SJ, Ritchie RO, Derynck R, Alliston T
• Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.
  The EMBO journal 2005 Kang JS, Alliston T, Delston R, Derynck R
• Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1.
  The Journal of biological chemistry 2005 Alliston T, Ko TC, Cao Y, Liang YY, Feng XH, Chang C, Derynck R
• Transforming growth factor-beta 1 regulation of collagenase-3 expression in osteoblastic cells by cross-talk between the Smad and MAPK signaling pathways and their components, Smad2 and Runx2.
  The Journal of biological chemistry 2004 Selvamurugan N, Kwok S, Alliston T, Reiss M, Partridge NC
• Medicine: interfering with bone remodelling.
  Nature 2002 Alliston T, Derynck R
• TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation.
  The EMBO journal 2001 Alliston T, Choy L, Ducy P, Karsenty G, Derynck R
• Expression and Localization of Serum/Glucocorticoid-Induced Kinase in the Rat Ovary: Relation to Follicular Growth and Differentiation1.
  Endocrinology 2000 Tamara N. Alliston, Ignacio J. Gonzalez-Robayna, Patricia Buse, Gary L. Firestone, JoAnne S. Richards
• Expression and localization of serum/glucocorticoid-induced kinase in the rat ovary: relation to follicular growth and differentiation.
  Endocrinology 2000 Alliston TN, Gonzalez-Robayna IJ, Buse P, Firestone GL, Richards JS
• Functional and subcellular changes in the A-kinase-signaling pathway: relation to aromatase and Sgk expression during the transition of granulosa cells to luteal cells.
  Molecular endocrinology (Baltimore, Md.) 1999 Gonzalez-Robayna IJ, Alliston TN, Buse P, Firestone GL, Richards JS
• Molecular mechanisms of ovulation and luteinization.
  Molecular and cellular endocrinology 1998 Richards JS, Russell DL, Robker RL, Dajee M, Alliston TN
• Follicle stimulating hormone-regulated expression of serum/glucocorticoid-inducible kinase in rat ovarian granulosa cells: a functional role for the Sp1 family in promoter activity.
  Molecular endocrinology (Baltimore, Md.) 1997 Alliston TN, Maiyar AC, Buse P, Firestone GL, Richards JS
• Ovarian cell differentiation: a cascade of multiple hormones, cellular signals, and regulated genes.
  Recent progress in hormone research 1995 Richards JS, Fitzpatrick SL, Clemens JW, Morris JK, Alliston T, Sirois J