Sumita Bhardwaj
Staff Research Associate IV
Institute for Neurodegenerative Diseases
School of Medicine

Publications (9)

Top publication keywords:
Mutant ProteinsCreutzfeldt-Jakob SyndromeBrainThiazolesPrionsAmidesEncephalopathy, Bovine SpongiformPrion DiseasesDrug DiscoveryPrPSc ProteinsPrion ProteinsArvicolinaeGerstmann-Straussler-Scheinker DiseaseDrug ResistanceWasting Disease, Chronic

• Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.
  Journal of virology 2016 Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB
• Towards authentic transgenic mouse models of heritable PrP prion diseases.
  Acta neuropathologica 2016 Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB
• Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.
  The Journal of pharmacology and experimental therapeutics 2016 Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB
• Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation.
  Annals of neurology 2015 Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB
• Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
  The Journal of pharmacology and experimental therapeutics 2015 Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB

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• Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice.
  The Journal of infectious diseases 2015 Berry D, Giles K, Oehler A, Bhardwaj S, DeArmond SJ, Prusiner SB
• Drug resistance confounding prion therapeutics.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K
• Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB
• Protease-resistant prions selectively decrease Shadoo protein.
  PLoS pathogens 2011 Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB