Steven Seyedin, MD
Assistant Professor
Radiation Oncology
School of Medicine

Awards

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• Prostate Cancer Research Pilot Award, UCSF, 2024-2025

Publications (38)

Top publication keywords:
Poly(ADP-ribose) PolymerasesKiller Cells, NaturalNeoplasm StagingRadioimmunotherapyImmunotherapy, AdoptiveNeoplasm Recurrence, LocalLymph Node ExcisionEsophageal NeoplasmsCarcinoma, Non-Small-Cell LungChemoradiotherapyEsophagectomyRadiotherapyLymph NodesProstatectomyPoly(ADP-ribose) Polymerase Inhibitors

• Observation of acute toxicity events in lung cancer patients treated concurrently with a tyrosine kinase inhibitor.
  Cancer treatment and research communications 2025 Harada GK, Ku E, Munjal A, Yeakel J, Juma S, Maxim P, Seyedin S, Nagasaka M, Chen A, Harris J
• A Predictive Nomogram for Development of Lymph Node Metastasis in Muscle-Invasive Bladder Cancer Following Neoadjuvant Therapy.
  Advances in radiation oncology 2024 Harada GK, Seyedin SN, Heutlinger O, Azizi A, Hsu A, Rezazadeh A, Daneshvar M, Gin GE, Uchio EM, Giannico GA, Harris JP, Simon AB, Kuo JV, Mar N
• Socioeconomic Barriers to Receiving Early Salvage Radiotherapy for Locally Advanced Prostate Adenocarcinoma: A Retrospective Single-Center Study.
  Cureus 2024 Heutlinger O, Azizi A, Harada G, Harris JP, Daneshvar M, Gin G, Uchio E, Mar N, Rezazadeh A, Seyedin SN
• Use of Radiation Therapy for Ataxia-Telangiectasia Mutated (ATM)-Mutation Metastatic Renal Cell Carcinoma: A Case Report.
  Cureus 2024 Seyedin SN, Harada G, Garemanian E, Rafizadeh D, Kaakour D, Dwabe S, Daneshvar M, Mar N
• The Impact of Local Control on Overall Survival after Y-90 Selective Internal Radiotherapy of Liver Metastases in Oligometastatic Cancer: A Retrospective Analysis.
  Cancers 2024 Yeakel J, Seyedin SN, Harada G, Hagopian G, Mahmood S, Bennett R, Harris JP, Abbott EM, Lindner S, Dayyani F, Sehgal V, Kuo JV, Abi-Jaoudeh N

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• Integrating Overall Survival and Tumor Control Probability Models to Predict Local Progression After Brain Metastasis Radiosurgery.
  Advances in radiation oncology 2024 Simon AB, Quezada J, Mohyeldin A, Harris J, Shi M, Seyedin S, Sehgal V, Chen AM
• A Pilot Study of Pembrolizumab Combined With Stereotactic Ablative Radiotherapy for Patients With Advanced or Metastatic Sarcoma.
  Cancer control : journal of the Moffitt Cancer Center 2024 Harris JP, Park J, Ku E, Seyedin S, Stitzlein R, Goldin A, Chen WP, McLaren C, Chen AM, Chow W
• Therapy With Metronomic Cyclophosphamide (mCyc) for Previously-Treated Metastatic Castrate-Resistant Prostate Cancer (mCRPC).
  Clinical genitourinary cancer 2023 Mar N, Dwabe S, Baranda MN, Zarrabi KK, Eturi A, Gulati S, Parikh M, Seyedin SN, Kalebasty AR
• The Correlation Between Lymphocyte Nadir and Radiation Therapy for Soft Tissue Sarcoma: Defining Key Dosimetric Parameters and Outlining Clinical Significance.
  Advances in radiation oncology 2023 Ku E, Harada G, Chiao E, Rao P, Hosseinian S, Seyedin S, Healy E, Maxim P, Chow W, Stitzlein R, Limoli C, Harris J
• Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients.
  Biosensors & bioelectronics 2023 Poellmann MJ, Bu J, Liu S, Wang AZ, Seyedin SN, Chandrasekharan C, Hong H, Kim Y, Caster JM, Hong S
• Combination of Pembrolizumab and Stereotactic Body Radiation Therapy in Recurrent Metastatic Penile Squamous Cell Carcinoma: A Case Study.
  Biomedicines 2022 Kaakour D, Seyedin S, Houshyar R, Mar N
• The potential of biology-guided radiation therapy in thoracic cancer: A preliminary treatment planning study.
  Frontiers in oncology 2022 Seyedin SN, Bassalow R, Mawlawi OR, Turner LM, Patel RR, Mazin SR, Oderinde OM, Voronenko Y, Wages CA, Olcott PD, Chang JY, Balter PA, Welsh JW
• A phase Ib feasibility trial of response adapted neoadjuvant therapy in gastric cancer (RANT-GC).
  Future oncology (London, England) 2022 Dayyani F, Smith BR, Nguyen NT, Daly S, Hinojosa MW, Seyedin SN, Kuo J, Samarasena JB, Lee JG, Taylor TH, Cho MT, Senthil M
• Controversies in Lung Cancer: Heterogeneity in Treatment Recommendations for Stage III NSCLC According to Disease Burden and Oncogenic Driver Alterations.
  Clinical lung cancer 2022 Harris JP, Fujimoto DK, Nagasaka M, Ku E, Harada G, Keshava H, Mahtabifard A, Longoria J, Patel N, Seyedin S, Simon A, Chen A
• A Recursive Partitioning Analysis Demonstrating Risk Subsets for 8-Year Biochemical Relapse After Margin-Positive Radical Prostatectomy Without Adjuvant Hormone or Radiation Therapy.
  Advances in radiation oncology 2021 Seyedin SN, Watkins JM, Mayo Z, Snow AN, Laszewski M, Russo JK, Mott SL, Tracy CR, Smith MC, Buatti JM, Caster JM
• The Role of Definitive Radiation and Surgery in Metastatic Esophageal Cancer: An NCDB Investigation.
  The Annals of thoracic surgery 2020 Seyedin SN, Parekh KR, Ginader T, Caster JM
• The Effect of Concurrent Stereotactic Body Radiation and Anti-PD-1 Therapy for Recurrent Metastatic Sarcoma.
  Radiation research 2020 Callaghan CM, Seyedin SN, Mohiuddin IH, Hawkes KL, Petronek MS, Anderson CM, Buatti JM, Milhem MM, Monga V, Allen BG
• Safety and Efficacy of Stereotactic Body Radiation Therapy for Locoregional Recurrences After Prior Chemoradiation for Advanced Esophageal Carcinoma.
  Frontiers in oncology 2020 Seyedin SN, Gannon MK, Plichta KA, Abushahin L, Berg DJ, Arshava EV, Parekh KR, Keech JC, Caster JM, Welsh JW, Allen BG
• Local management of preinvasive and clinical T1-3 penile cancer: utilization of diverse treatment modalities.
  Future oncology (London, England) 2020 Menon H, Patel RR, Ludmir EB, Muralidhar V, Cushman TR, Amini A, Seyedin SN, Nguyen PL, Verma V
• Management and outcomes of primary anorectal melanoma in the United States.
  Future oncology (London, England) 2020 Menon H, Patel RR, Cushman TR, Amini A, Seyedin SN, Adams AC, Lin C, Verma V
• Combination Therapy with Radiation and PARP Inhibition Enhances Responsiveness to Anti-PD-1 Therapy in Colorectal Tumor Models.
  International journal of radiation oncology, biology, physics 2020 Seyedin SN, Hasibuzzaman MM, Pham V, Petronek MS, Callaghan C, Kalen AL, Mapuskar KA, Mott SL, Spitz DR, Allen BG, Caster JM
• Deep segmentation networks predict survival of non-small cell lung cancer.
  Scientific reports 2019 Baek S, He Y, Allen BG, Buatti JM, Smith BJ, Tong L, Sun Z, Wu J, Diehn M, Loo BW, Plichta KA, Seyedin SN, Gannon M, Cabel KR, Kim Y, Wu X
• Results of a Phase 1/2 Trial of Chemoradiotherapy With Simultaneous Integrated Boost of Radiotherapy Dose in Unresectable Locally Advanced Esophageal Cancer.
  JAMA oncology 2019 Chen D, Menon H, Verma V, Seyedin SN, Ajani JA, Hofstetter WL, Nguyen QN, Chang JY, Gomez DR, Amini A, Swisher SG, Blum MA, Younes AI, Barsoumian HB, Erasmus JJ, Lee JH, Bhutani MS, Hess KR, Minsky BD…
• First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Allen BG, Bodeker KL, Smith MC, Monga V, Sandhu S, Hohl R, Carlisle T, Brown H, Hollenbeck N, Vollstedt S, Greenlee JD, Howard MA, Mapuskar KA, Seyedin SN, Caster JM, Jones KA, Cullen JJ, Berg D, …
• Optimizing Advances in Nanoparticle Delivery for Cancer Immunotherapy.
  Advanced drug delivery reviews 2019 Caster JM, Callaghan C, Seyedin SN, Henderson K, Sun B, Wang AZ
• Clinical Utility of Pretreatment and 3-Month 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Standardized Uptake Value in Predicting and Assessing Recurrence in T3-T4 Laryngeal Carcinoma Treated With Definitive Radiation.
  The Annals of otology, rhinology, and laryngology 2019 Mayo Z, Seyedin SN, Mallak N, Mott SL, Menda Y, Graham M, Anderson C
• Cutaneous malignant melanoma of the oral cavity following skin graft reconstruction: Case report.
  Head & neck 2018 Mayo Z, Seyedin S, Marquardt M, Mohiuddin I, Milhem M, Liu V, Pagedar N, Anderson C
• Is More Always Better? An Assessment of the Impact of Lymph Node Yield on Outcome for Clinically Localized Prostate Cancer with Low/Intermediate Risk Pathology (pT2-3a/pN0) Managed with Prostatectomy Alone.
  Pathology oncology research : POR 2017 Seyedin SN, Mitchell DL, Mott SL, Russo JK, Tracy CR, Snow AN, Parkhurst JR, Smith MC, Buatti JM, Watkins JM
• Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation.
  Translational lung cancer research 2017 Schoenhals JE, Seyedin SN, Anderson C, Brooks ED, Li YR, Younes AI, Niknam S, Li A, Barsoumian HB, Cortez MA, Welsh JW
• Local Control and Toxicity of a Simultaneous Integrated Boost for Dose Escalation in Locally Advanced Esophageal Cancer: Interim Results from a Prospective Phase I/II Trial.
  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 Welsh JW, Seyedin SN, Allen PK, Hofstetter WL, Ajani JA, Chang JY, Gomez DR, Amini A, Swisher SG, Blum MA, Younes AI, Nguyen QN, Minsky BD, Erasmus JJ, Lee JH, Bhutani M, Komaki RU
• Preclinical Rationale and Clinical Considerations for Radiotherapy Plus Immunotherapy: Going Beyond Local Control.
  Cancer journal (Sudbury, Mass.) 2016 Schoenhals JE, Seyedin SN, Tang C, Cortez MA, Niknam S, Tsouko E, Chang JY, Hahn SM, Welsh JW
• Strategies for combining immunotherapy with radiation for anticancer therapy.
  Immunotherapy 2015 Seyedin SN, Schoenhals JE, Lee DA, Cortez MA, Wang X, Niknam S, Tang C, Hong DS, Naing A, Sharma P, Allison JP, Chang JY, Gomez DR, Heymach JV, Komaki RU, Cooper LJ, Welsh JW
• Author's view: radiation and immunotherapy as systemic therapy for solid tumors.
  Oncoimmunology 2015 Seyedin SN, Tang C, Welsh JW
• Galectin-1 and immune suppression during radiotherapy.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2014 Welsh JW, Seyedin SN, Cortez MA, Maity A, Hahn SM
• Combining radiation and immunotherapy: a new systemic therapy for solid tumors?
  Cancer immunology research 2014 Tang C, Wang X, Soh H, Seyedin S, Cortez MA, Krishnan S, Massarelli E, Hong D, Naing A, Diab A, Gomez D, Ye H, Heymach J, Komaki R, Allison JP, Sharma P, Welsh JW
• Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.
  PloS one 2010 Wang J, Taherbhoy AM, Hunt HW, Seyedin SN, Miller DW, Miller DJ, Huang DT, Schulman BA
• Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
  Molecular cell 2009 Zhuang M, Calabrese MF, Liu J, Waddell MB, Nourse A, Hammel M, Miller DJ, Walden H, Duda DM, Seyedin SN, Hoggard T, Harper JW, White KP, Schulman BA
• The mechanism of ATP-dependent primer-template recognition by a clamp loader complex.
  Cell 2009 Simonetta KR, Kazmirski SL, Goedken ER, Cantor AJ, Kelch BA, McNally R, Seyedin SN, Makino DL, O'Donnell M, Kuriyan J