Steven Rosen, PhD
Professor Emeritus
Anatomy
School of Medicine
Grants and Projects
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- Bio-Organic Biomedical Mass Spectrometry Resource, NIH, 1982-2015
- Mucosal Immune Barrier in Infection and Immunity, NIH, 2002-2014
- Sulfotransferases in the Synthesis of L-Selectin Ligands, NIH, 1999-2012
- Cell Surface Lectins and Intercellular Adhesion, NIH, 1977-2012
- Role of Heparan Sulfate-Degrading Sulfatases in Pancreatic Adenocarcinomas, NIH, 2006-2009
- Interactions of Lymphocytes, Cytokines and Airway Cells, NIH, 1996-2006
- Cell Surface Lectins and Intercellular Adhesion, NIH, 1977-2006
- Conference: Molecular Mechanism of Leukocyte Trafficking, NIH, 2002-2003
- Molecular Mechanisms of Leukocyte Trafficking, NIH, 1998-1999
- L-selectin in Leukocyte Myelin Interactions, NIH, 1994-1998
Publications (183)
Top publication keywords:
Endothelium, VascularVenulesHeparitin SulfateL-SelectinSulfotransferasesCell Adhesion MoleculesLymphocytesEndotheliumEndothelium, LymphaticCell AdhesionSulfatasesReceptors, Lymphocyte HomingAntigens, SurfaceLymph NodesMucins
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Pembrolizumab plus vorinostat induces responses in patients with Hodgkin lymphoma refractory to prior PD-1 blockade.
Blood 2023 Mei M, Chen L, Godfrey J, Song J, Egelston C, Puverel S, Budde LE, Armenian S, Nikolaenko L, Nwangwu M, Guo W, Gao L, Lee P, Chen R, Daniels S, Kennedy N, Peters L, Zain J, Rosen S, Forman S, … -
Leflunomide Confers Rapid Recovery from COVID-19 and is Coupled with Temporal Immunologic Changes.
Journal of immunological sciences 2023 Dona AA, Sanchez JF, Palmer JM, Synold TW, Chiuppesi F, Thomas S, Caserta E, Singer M, Tandoh T, Chowdhury A, Krishnan A, Rosenzweig M, Diamond DJ, Rosen S, Pichiorri F, Dadwal S -
Response-adapted anti-PD-1-based salvage therapy for Hodgkin lymphoma with nivolumab alone or in combination with ICE.
Blood 2022 Mei MG, Lee HJ, Palmer JM, Chen R, Tsai NC, Chen L, McBride K, Smith DL, Melgar I, Song JY, Bonjoc KJ, Armenian S, Nwangwu M, Lee PP, Zain J, Nikolaenko L, Popplewell L, Nademanee A, Chaudhry A, Rosen… -
Sulfatase 2 (SULF2) Monoclonal Antibody 5D5 Suppresses Human Cholangiocarcinoma Xenograft Growth Through Regulation of a SULF2-Platelet-Derived Growth Factor Receptor Beta-Yes-Associated Protein Signaling Axis.
Hepatology (Baltimore, Md.) 2021 Luo X, Campbell NA, He L, O'Brien DR, Singer MS, Lemjabbar-Alaoui H, Ahn KS, Smoot R, Torbenson MS, Rosen SD, Roberts LR -
CD84 is a regulator of the immunosuppressive microenvironment in multiple myeloma.
JCI insight 2021 Lewinsky H, Gunes EG, David K, Radomir L, Kramer MP, Pellegrino B, Perpinial M, Chen J, He TF, Mansour AG, Teng KY, Bhattacharya S, Caserta E, Troadec E, Lee P, Feng M, Keats J, Krishnan A, Rosenzweig…
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Early Targeting of L-Selectin on Leukocytes Promotes Recovery after Spinal Cord Injury, Implicating Novel Mechanisms of Pathogenesis.
eNeuro 2018 McCreedy DA, Lee S, Sontag CJ, Weinstein P, Olivas AD, Martinez AF, Fandel TM, Trivedi A, Lowell CA, Rosen SD, Noble-Haeusslein LJ -
Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck.
Oncotarget 2016 Flowers SA, Zhou X, Wu J, Wang Y, Makambi K, Kallakury BV, Singer MS, Rosen SD, Davidson B, Goldman R -
SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis.
Clinica chimica acta; international journal of clinical chemistry 2014 Singer MS, Phillips JJ, Lemjabbar-Alaoui H, Wang YQ, Wu J, Goldman R, Rosen SD -
High endothelial venules through a transcriptomics lens.
Nature immunology 2014 Rosen SD, Daneman R -
Leukotriene B4 amplifies eosinophil accumulation in response to nematodes.
The Journal of experimental medicine 2014 Patnode ML, Bando JK, Krummel MF, Locksley RM, Rosen SD -
The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.
PloS one 2013 Maltseva I, Chan M, Kalus I, Dierks T, Rosen SD -
Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.
The Journal of biological chemistry 2013 Patnode ML, Cheng CW, Chou CC, Singer MS, Elin MS, Uchimura K, Crocker PR, Khoo KH, Rosen SD -
Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.
Cellular microbiology 2013 Kim JH, Chan C, Elwell C, Singer MS, Dierks T, Lemjabbar-Alaoui H, Rosen SD, Engel JN -
KSGal6ST generates galactose-6-O-sulfate in high endothelial venules but does not contribute to L-selectin-dependent lymphocyte homing.
Glycobiology 2012 Patnode ML, Yu SY, Cheng CW, Ho MY, Tegesjö L, Sakuma K, Uchimura K, Khoo KH, Kannagi R, Rosen SD -
SULF2 expression by immunohistochemistry and overall survival in oesophageal cancer: a cohort study.
BMJ open 2012 Lui NS, van Zante A, Rosen SD, Jablons DM, Lemjabbar-Alaoui H -
Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells.
Journal of immunology (Baltimore, Md. : 1950) 2012 Zhang Y, Chen YC, Krummel MF, Rosen SD -
Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma.
The Journal of clinical investigation 2012 Phillips JJ, Huillard E, Robinson AE, Ward A, Lum DH, Polley MY, Rosen SD, Rowitch DH, Werb Z -
Prevention of both neutrophil and monocyte recruitment promotes recovery after spinal cord injury.
Journal of neurotrauma 2011 Lee SM, Rosen S, Weinstein P, van Rooijen N, Noble-Haeusslein LJ -
Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs.
The American journal of pathology 2010 Arata-Kawai H, Singer MS, Bistrup A, Zante Av, Wang YQ, Ito Y, Bao X, Hemmerich S, Fukuda M, Rosen SD -
Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate.
Expert opinion on therapeutic targets 2010 Rosen SD, Lemjabbar-Alaoui H -
Use of a phage display antibody to measure the enzymatic activity of the Sulfs.
Methods in enzymology 2010 Uchimura K, Lemjabbar-Alaoui H, van Kuppevelt TH, Rosen SD -
Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.
Oncogene 2009 Lemjabbar-Alaoui H, van Zante A, Singer MS, Xue Q, Wang YQ, Tsay D, He B, Jablons DM, Rosen SD -
Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88.
Glycobiology 2009 Hossain MM, Hosono-Fukao T, Tang R, Sugaya N, van Kuppevelt TH, Jenniskens GJ, Kimata K, Rosen SD, Uchimura K -
"Home sweet home" for lymphocytes.
Blood 2009 Rosen SD, Arata-Kawai H -
Functional consequences of the subdomain organization of the sulfs.
The Journal of biological chemistry 2009 Tang R, Rosen SD -
Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins.
Journal of immunology (Baltimore, Md. : 1950) 2008 Kerr SC, Fieger CB, Snapp KR, Rosen SD -
Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.
Nature immunology 2008 Kanda H, Newton R, Klein R, Morita Y, Gunn MD, Rosen SD -
Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells.
PloS one 2007 Nawroth R, van Zante A, Cervantes S, McManus M, Hebrok M, Rosen SD -
Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs.
Nature immunology 2007 Veerman KM, Williams MJ, Uchimura K, Singer MS, Merzaban JS, Naus S, Carlow DA, Owen P, Rivera-Nieves J, Rosen SD, Ziltener HJ -
Rolling on N-linked glycans: a new way to present L-selectin binding sites.
Nature immunology 2007 Alon R, Rosen S -
Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.
Molecular and cellular biology 2006 Lum DH, Tan J, Rosen SD, Werb Z -
Sulfated L-selectin ligands as a therapeutic target in chronic inflammation.
Trends in immunology 2006 Uchimura K, Rosen SD -
Homing in on L-selectin.
Journal of immunology (Baltimore, Md. : 1950) 2006 Rosen SD -
Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis.
BMC immunology 2006 Yang J, Rosen SD, Bendele P, Hemmerich S -
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.
BMC biochemistry 2006 Uchimura K, Morimoto-Tomita M, Bistrup A, Li J, Lyon M, Gallagher J, Werb Z, Rosen SD -
Measuring the activities of the Sulfs: two novel heparin/heparan sulfate endosulfatases.
Methods in enzymology 2006 Uchimura K, Morimoto-Tomita M, Rosen SD -
Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.
Neoplasia (New York, N.Y.) 2005 Morimoto-Tomita M, Uchimura K, Bistrup A, Lum DH, Egeblad M, Boudreau N, Werb Z, Rosen SD -
A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules.
Nature immunology 2005 Uchimura K, Gauguet JM, Singer MS, Tsay D, Kannagi R, Muramatsu T, von Andrian UH, Rosen SD -
Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase.
Glycobiology 2005 Saad OM, Ebel H, Uchimura K, Rosen SD, Bertozzi CR, Leary JA -
A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.
BMC immunology 2005 Pablos JL, Santiago B, Tsay D, Singer MS, Palao G, Galindo M, Rosen SD -
Therapeutic targeting of endothelial ligands for L-selectin (PNAd) in a sheep model of asthma.
The American journal of pathology 2005 Rosen SD, Tsay D, Singer MS, Hemmerich S, Abraham WM -
Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes.
Blood 2004 Gauguet JM, Rosen SD, Marth JD, von Andrian UH -
N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing.
The Journal of biological chemistry 2004 Uchimura K, Kadomatsu K, El-Fasakhany FM, Singer MS, Izawa M, Kannagi R, Takeda N, Rosen SD, Muramatsu T -
Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope.
The American journal of pathology 2004 Bistrup A, Tsay D, Shenoy P, Singer MS, Bangia N, Luther SA, Cyster JG, Ruddle NH, Rosen SD -
Differential gene expression profile of human tonsil high endothelial cells: implications for lymphocyte trafficking.
Journal of leukocyte biology 2004 Palmeri D, Zuo FR, Rosen SD, Hemmerich S -
Experimental Medicine
Novel extracellular sulfatases regulate the signaling by heparin-binding growth factors 2004 Tomita-Morimoto M, Uchimura K, Rosen SD -
Ligands for L-selectin: homing, inflammation, and beyond.
Annual review of immunology 2004 Rosen SD -
Lymphocyte-HEV interactions in lymph nodes of a sulfotransferase-deficient mouse.
The Journal of experimental medicine 2003 van Zante A, Gauguet JM, Bistrup A, Tsay D, von Andrian UH, Rosen SD -
Low force decelerates L-selectin dissociation from P-selectin glycoprotein ligand-1 and endoglycan.
The Journal of biological chemistry 2003 Sarangapani KK, Yago T, Klopocki AG, Lawrence MB, Fieger CB, Rosen SD, McEver RP, Zhu C -
The use of flow cytometry to assess neutrophil infiltration in the injured murine spinal cord.
Journal of neuroscience methods 2003 Tjoa T, Strausbaugh HJ, Maida N, Dazin PF, Rosen SD, Noble-Haeusslein LJ -
Endoglycan, a member of the CD34 family, functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x.
The Journal of biological chemistry 2003 Fieger CB, Sassetti CM, Rosen SD -
Sulphated endothelial ligands for L-selectin in lymphocyte homing and inflammation.
Biochemical Society transactions 2003 van Zante A, Rosen SD -
Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface.
Science (New York, N.Y.) 2003 Genbacev OD, Prakobphol A, Foulk RA, Krtolica AR, Ilic D, Singer MS, Yang ZQ, Kiessling LL, Rosen SD, Fisher SJ -
Trends in Glycoscience and Glycotechnology
Novel extracellular sulfatases: potential roles in cancer 2003 Morimoto-Tomita M, Uchimura K, Rosen SD -
Activities and expression pattern of the carbohydrate sulfotransferase GlcNAc6ST-3 (I-GlcNAc6ST): functional implications.
Glycobiology 2002 Lee JK, Bistrup A, van Zante A, Rosen SD -
Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.
The Journal of biological chemistry 2002 Morimoto-Tomita M, Uchimura K, Werb Z, Hemmerich S, Rosen SD -
Handbook of Glycosyltransferases and Related Genes, Taniguchi N, Honke K, Fukuda M, editors
High Endothelial Cell N-Acetylglucamine 6-O-Sulfotranferase 2002 Bistrup A, Rosen SD -
P-selectin mediates the adhesion of sickle erythrocytes to the endothelium.
Blood 2001 Matsui NM, Borsig L, Rosen SD, Yaghmai M, Varki A, Embury SH -
Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes.
Immunity 2001 Hemmerich S, Bistrup A, Singer MS, van Zante A, Lee JK, Tsay D, Peters M, Carminati JL, Brennan TJ, Carver-Moore K, Leviten M, Fuentes ME, Ruddle NH, Rosen SD -
Polymerized liposome assemblies: bifunctional macromolecular selectin inhibitors mimicking physiological selectin ligands.
Biochemistry 2001 Bruehl RE, Dasgupta F, Katsumoto TR, Tan JH, Bertozzi CR, Spevak W, Ahn DJ, Rosen SD, Nagy JO -
A potential role for annexin 1 as a physiologic mediator of glucocorticoid-induced L-selectin shedding from myeloid cells.
Journal of immunology (Baltimore, Md. : 1950) 2001 Strausbaugh HJ, Rosen SD -
Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.
Glycobiology 2001 Hemmerich S, Lee JK, Bhakta S, Bistrup A, Ruddle NR, Rosen SD -
Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5).
The Journal of biological chemistry 2000 Bhakta S, Bartes A, Bowman KG, Kao WM, Polsky I, Lee JK, Cook BN, Bruehl RE, Rosen SD, Bertozzi CR, Hemmerich S -
Minimal sulfated carbohydrates for recognition by L-selectin and the MECA-79 antibody.
The Journal of biological chemistry 2000 Bruehl RE, Bertozzi CR, Rosen SD -
Carbohydrate sulfotransferases in lymphocyte homing.
Glycobiology 2000 Hemmerich S, Rosen SD -
Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells.
The Journal of biological chemistry 2000 Palmeri D, van Zante A, Huang CC, Hemmerich S, Rosen SD -
Identification of endoglycan, a member of the CD34/podocalyxin family of sialomucins.
The Journal of biological chemistry 2000 Sassetti C, Van Zante A, Rosen SD -
Sulfation of a high endothelial venule-expressed ligand for L-selectin. Effects on tethering and rolling of lymphocytes.
The Journal of experimental medicine 1999 Tangemann K, Bistrup A, Hemmerich S, Rosen SD -
Endothelial ligands for L-selectin: from lymphocyte recirculation to allograft rejection.
The American journal of pathology 1999 Rosen SD -
Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue.
Biochemical and biophysical research communications 1999 Lee JK, Bhakta S, Rosen SD, Hemmerich S -
Painful stimulation suppresses joint inflammation by inducing shedding of L-selectin from neutrophils.
Nature medicine 1999 Strausbaugh HJ, Green PG, Lo E, Tangemann K, Reichling DB, Rosen SD, Levine JD -
Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation.
European journal of immunology 1999 Papadopoulos EJ, Sassetti C, Saeki H, Yamada N, Kawamura T, Fitzhugh DJ, Saraf MA, Schall T, Blauvelt A, Rosen SD, Hwang ST -
Separate oligosaccharide determinants mediate interactions of the low-molecular-weight salivary mucin with neutrophils and bacteria.
Biochemistry 1999 Prakobphol A, Tangemann K, Rosen SD, Hoover CI, Leffler H, Fisher SJ -
Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.
The Journal of cell biology 1999 Bistrup A, Bhakta S, Lee JK, Belov YY, Gunn MD, Zuo FR, Huang CC, Kannagi R, Rosen SD, Hemmerich S -
Guidebook to the Extracellular Matrix and Adhesion Proteins, Kreis T, Vale R, editors
The selectins 1999 Rosen SD -
Oligosaccharides in Chemistry and Biology, Ernst B, Sinay P, Hart G, editors
Carbohydrate sulfotransferases 1999 Rosen SD, Bistrup A, Hemmerich S -
A high endothelial cell-derived chemokine induces rapid, efficient, and subset-selective arrest of rolling T lymphocytes on a reconstituted endothelial substrate.
Journal of immunology (Baltimore, Md. : 1950) 1998 Tangemann K, Gunn MD, Giblin P, Rosen SD -
Identification of an N-acetylglucosamine-6-0-sulfotransferase activity specific to lymphoid tissue: an enzyme with a possible role in lymphocyte homing.
Chemistry & biology 1998 Bowman KG, Hemmerich S, Bhakta S, Singer MS, Bistrup A, Rosen SD, Bertozzi CR -
Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34.
The Journal of experimental medicine 1998 Sassetti C, Tangemann K, Singer MS, Kershaw DB, Rosen SD -
Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity.
Biochemistry 1998 Prakobphol A, Thomsson KA, Hansson GC, Rosen SD, Singer MS, Phillips NJ, Medzihradszky KF, Burlingame AL, Leffler H, Fisher SJ -
Affinity and kinetic analysis of L-selectin (CD62L) binding to glycosylation-dependent cell-adhesion molecule-1.
The Journal of biological chemistry 1998 Nicholson MW, Barclay AN, Singer MS, Rosen SD, van der Merwe PA -
A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998 Gunn MD, Tangemann K, Tam C, Cyster JG, Rosen SD, Williams LT -
GlyCAM-1 supports leukocyte rolling in flow: evidence for a greater dynamic stability of L-selectin rolling of lymphocytes than of neutrophils.
Cell adhesion and communication 1998 Dwir O, Shimron F, Chen C, Singer MS, Rosen SD, Alon R -
Ligation of L-selectin on T lymphocytes activates beta1 integrins and promotes adhesion to fibronectin.
Journal of immunology (Baltimore, Md. : 1950) 1997 Giblin PA, Hwang ST, Katsumoto TR, Rosen SD -
High-endothelial-venule ligands for L-selectin: identification and functions.
Biochemical Society transactions 1997 Rosen SD, Hwang ST, Giblin PA, Singer MS -
An ELISA for selectins based on binding to a physiological ligand.
Journal of immunological methods 1997 Bertozzi CR, Singer MS, Rosen SD -
L-selectin-carbohydrate interactions: relevant modifications of the Lewis x trisaccharide.
Biochemistry 1996 Sanders WJ, Katsumoto TR, Bertozzi CR, Rosen SD, Kiessling LL -
GlyCAM-1, a physiologic ligand for L-selectin, activates beta 2 integrins on naive peripheral lymphocytes.
The Journal of experimental medicine 1996 Hwang ST, Singer MS, Giblin PA, Yednock TA, Bacon KB, Simon SI, Rosen SD -
Purification and quantification of L-selectin-reactive GlyCAM-1 from mouse serum.
Journal of immunological methods 1996 Singer MS, Rosen SD -
Two selectins converge on sulphate. Leukocyte adhesion.
Current biology : CB 1996 Rosen SD, Bertozzi CR -
Calcium-dependent lectin activity with novel distribution on thymocyte subsets.
European journal of immunology 1996 Mallett S, Rosen SD, Hyun W -
Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice.
The Journal of clinical investigation 1996 Onrust SV, Hartl PM, Rosen SD, Hanahan D -
Tin-mediated phosphorylation: synthesis and selectin binding of a phospho Lewis a analog
Tetrahedron letters 1996 Manning DD, Bertozzi CR, Rosen SD -
Sulfated disaccharide inhibitors of L-selectin: deriving structural leads from a physiological selectin ligand.
Biochemistry 1995 Bertozzi CR, Fukuda S, Rosen SD -
Biosynthesis of GlyCAM-1, a mucin-like ligand for L-selectin.
The Journal of biological chemistry 1995 Crommie D, Rosen SD -
Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin.
The Journal of biological chemistry 1995 Hemmerich S, Leffler H, Rosen SD -
The L-selectin counter-receptor in porcine lymph nodes.
Biochemical Society transactions 1995 Whyte A, Wooding P, Nayeem N, Watson SR, Rosen SD, Binns RM -
Cellular and Molecular Mechanisms, Prevention, and Treatment, Gallo L editor
A Lectin-like receptor involved in normal lymphocyte recirculation and inflammatory leukocyte trafficking 1995 Rosen SD -
Selectin-saccharide interactions: revealing structure-function relationships with chemical synthesis
J. Organic Chem 1995 Manning DD, Bertozzi CR, Pohl NL, Rosen SD, Kiessling LL -
Localization of ligands for L-selectin in mouse peripheral lymph node high endothelial cells by colloidal gold conjugates.
Blood 1994 Kikuta A, Rosen SD -
Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain.
Immunity 1994 Daniels BF, Nakamura MC, Rosen SD, Yokoyama WM, Seaman WE -
Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody.
The Journal of experimental medicine 1994 Hemmerich S, Butcher EC, Rosen SD -
The selectins and their ligands.
Current opinion in cell biology 1994 Rosen SD, Bertozzi CR -
Myelin localization of a central nervous system ligand for L-selectin.
Journal of neuroimmunology 1994 Huang K, Kikuta A, Rosen SD -
6'-sulfated sialyl Lewis x is a major capping group of GlyCAM-1.
Biochemistry 1994 Hemmerich S, Rosen SD -
Identification of the sulfated monosaccharides of GlyCAM-1, an endothelial-derived ligand for L-selectin.
Biochemistry 1994 Hemmerich S, Bertozzi CR, Leffler H, Rosen SD -
Ligands for L-selectin: where and how many?
Research in immunology 1993 Rosen SD -
Binding of L-selectin to the vascular sialomucin CD34.
Science (New York, N.Y.) 1993 Baumheter S, Singer MS, Henzel W, Hemmerich S, Renz M, Rosen SD, Lasky LA -
Robert Feulgen Lecture 1993. L-selectin and its biological ligands.
Histochemistry 1993 Rosen SD -
Cell surface lectins in the immune system.
Seminars in immunology 1993 Rosen SD -
Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin.
Nature 1993 Imai Y, Lasky LA, Rosen SD -
Direct demonstration of heterogeneous, sulfated O-linked carbohydrate chains on an endothelial ligand for L-selectin.
Glycoconjugate journal 1993 Imai Y, Rosen SD -
Structure and Function of Molecules Involved in Leukocyte Adhesion, Lipsky P, Rothlein R, Kishimoto K, Faines R, Smith CW, editors
L-selectin as a mediator of leukocyte binding to myelinated tracts of the central nervous system: possible pathophysiologic significance 1993 Rosen SD, Huang K -
Further characterization of the interaction between L-selectin and its endothelial ligands.
Glycobiology 1992 Imai Y, Lasky LA, Rosen SD -
An endothelial ligand for L-selectin is a novel mucin-like molecule.
Cell 1992 Lasky LA, Singer MS, Dowbenko D, Imai Y, Henzel WJ, Grimley C, Fennie C, Gillett N, Watson SR, Rosen SD -
Glycosylation-dependent cell adhesion molecule 1: a novel mucin-like adhesion ligand for L-selectin.
Cold Spring Harbor symposia on quantitative biology 1992 Lasky LA, Singer MS, Dowbenko D, Imai Y, Henzel W, Fennie C, Watson S, Rosen SD -
Guidebook to the Extracellular Matrix and Adhesion Proteins Guidebook to the Extracellular Matrix and Adhesion Proteins, Kreis T, Vale R, editors
The selectins 1992 Rosen SD -
Inflammation- Basic Principles and Clinical Correlates, Gallin J, Goldstein I, Snyderman R, editors
The LEC-CAMs: carbohydrate-binding adhesion molecules of the immune system 1992 Lasky LA, Rosen SD -
Trends in glycoscience and glycotechnology
L-selectin, a lectin-like leukocyte adhesion receptor 1992 Rosen SD, Imai Y, Singer MS -
A lymphocyte homing receptor (L-selectin) mediates the in vitro attachment of lymphocytes to myelinated tracts of the central nervous system.
The Journal of clinical investigation 1991 Huang K, Geoffroy JS, Singer MS, Rosen SD -
The complement binding-like domains of the murine homing receptor facilitate lectin activity.
The Journal of cell biology 1991 Watson SR, Imai Y, Fennie C, Geoffrey J, Singer M, Rosen SD, Lasky LA -
Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo.
Blood 1991 Ley K, Gaehtgens P, Fennie C, Singer MS, Lasky LA, Rosen SD -
Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.
The Journal of cell biology 1991 Imai Y, Singer MS, Fennie C, Lasky LA, Rosen SD -
Requirement for sialic acid on the endothelial ligand of a lymphocyte homing receptor.
The Journal of cell biology 1990 True DD, Singer MS, Lasky LA, Rosen SD -
Requirement for sialic acid on neutrophils in a GMP-140 (PADGEM) mediated adhesive interaction with activated platelets.
Biochemical and biophysical research communications 1990 Corral L, Singer MS, Macher BA, Rosen SD -
The LEC-CAMs: an emerging family of cell-cell adhesion receptors based upon carbohydrate recognition.
American journal of respiratory cell and molecular biology 1990 Rosen SD -
Direct demonstration of the lectin activity of gp90MEL, a lymphocyte homing receptor.
The Journal of cell biology 1990 Imai Y, True DD, Singer MS, Rosen SD -
A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules.
The Journal of cell biology 1990 Watson SR, Imai Y, Fennie C, Geoffroy JS, Rosen SD, Lasky LA -
UCLA Symposia on Molecular and Cellular Biology, Welply JK, Jaworksi E, editors
A lymphocyte homing receptor is a lectin, a member of the emerging LEC-CAM family 1990 Rosen SD, Geoffroy JS, Lasky LA, Singer MS, Stachel S, Stoolman LM, True DD, Yednock TA -
Demonstration that a lectin-like receptor (gp90MEL) directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes.
The Journal of cell biology 1989 Geoffroy JS, Rosen SD -
Lymphocyte homing: progress and prospects.
Current opinion in cell biology 1989 Rosen SD -
Cloning of a lymphocyte homing receptor reveals a lectin domain.
Cell 1989 Lasky LA, Singer MS, Yednock TA, Dowbenko D, Fennie C, Rodriguez H, Nguyen T, Stachel S, Rosen SD -
Intravenously injected sialidase inactivates attachment sites for lymphocytes on high endothelial venules.
Journal of immunology (Baltimore, Md. : 1950) 1989 Rosen SD, Chi SI, True DD, Singer MS, Yednock TA -
Lymphocyte homing.
Advances in immunology 1989 Yednock TA, Rosen SD -
Progress in Immunology, Melchers F, editor
A lymphocyte homing receptor, a member of an emerging class of cell adhesion molecules 1989 Rosen SD -
Basement-membrane components associated with the extracellular matrix of the lymph node.
Cell and tissue research 1988 Kramer RH, Rosen SD, McDonald KA -
Proceedings of the Japanese-German Symposium on Sialic Acids , Schauer R, Yamakawa T, editors
In vivo desialylation of high endothelial venules inactivates attachment sites for blood borne lymphocytes 1988 Rosen SD, Chi SI, True DD, Singer MS, Yednock TA -
The Cell Surface, Mediator of Developmental Processes, Subtelny S, Wessells NK, editors
Use of teratocarcinoma cells as a model system for studying the cell surface during early mammalian development 1988 Martin GR, Grabel LB, Rosen SD -
Homing receptors on human and rodent lymphocytes--evidence for a conserved carbohydrate-binding specificity.
Blood 1987 Stoolman LM, Yednock TA, Rosen SD -
Phosphomannosyl-derivatized beads detect a receptor involved in lymphocyte homing.
The Journal of cell biology 1987 Yednock TA, Stoolman LM, Rosen SD -
Receptors involved in lymphocyte homing: relationship between a carbohydrate-binding receptor and the MEL-14 antigen.
The Journal of cell biology 1987 Yednock TA, Butcher EC, Stoolman LM, Rosen SD -
Lymphocyte attachment to high endothelial venules during recirculation: a possible role for carbohydrates as recognition determinants.
Molecular and cellular biochemistry 1986 Rosen SD, Yednock TA -
Microbial Lectins and Agglutinins , Mirelman D, editor
Lectins from cellular slime molds 1986 Rosen SD, True DD -
Vertebrate Lectins, Olden K, Parent JP, editors
Potential role of cell surface lectin in lymphocyte recirculation. 1986 Rosen SD, Stoolman LM -
Involvement of sialic acid on endothelial cells in organ-specific lymphocyte recirculation.
Science (New York, N.Y.) 1985 Rosen SD, Singer MS, Yednock TA, Stoolman LM -
Isolation of a teratocarcinoma stem cell lectin implicated in intercellular adhesion.
FEBS letters 1985 Grabel LB, Singer MS, Martin GR, Rosen SD -
Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules.
The Journal of cell biology 1984 Stoolman LM, Tenforde TS, Rosen SD -
Teratocarcinoma stem cell adhesion: the role of divalent cations and a cell surface lectin.
The Journal of cell biology 1983 Grabel LB, Singer MS, Martin GR, Rosen SD -
Reversible disruption of cultured endothelial monolayers by sulphated fucans.
Journal of cell science 1983 Glabe CG, Yednock T, Rosen SD -
Preparation and properties of fluorescent polysaccharides.
Analytical biochemistry 1983 Glabe CG, Harty PK, Rosen SD -
Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation.
The Journal of cell biology 1983 Stoolman LM, Rosen SD -
Cold Spring Harbor Conference on Cell Proliferation
The role of carbohydrates in the intercellular adhesion and differentiation of teratocarcinoma stem cells 1983 Grabel LB, Rosen SD, Singer MS, Martin GR -
Carbohydrate specificity of sea urchin sperm bindin: a cell surface lectin mediating sperm-egg adhesion.
The Journal of cell biology 1982 Glabe CG, Grabel LB, Vacquier VD, Rosen SD -
Identification and purification of an endogenous receptor for the lectin pallidin from Polysphondylium pallidum.
The Journal of cell biology 1982 Drake DK, Rosen SD -
Keystone Symposium on Cellular Recognition
The pallidin-receptor system in the intercellular adhesion of the cellular slime mold, Polysphondylium pallidum 1982 Drake DK, Rosen SD -
Keystone Symposium on Cellular Recognition, WA Frazier and L Glaser, editors
Teratocarcinoma stem cell lectin: characterization and proposed function. In: Keystone Symposium on Cellular Recognition 1982 Grabel LB, Martin GR, Rosen SD -
Slime mold lectins.
International review of cytology 1982 Bartles JR, Frazier WA, Rosen SD -
Teratocarcinoma and Embryonic Cell Interactions, Muramatsu T, Gachelin G, Moscona AA, Ikawa Y editors
Specificity and proposed role in intercellular adhesion of a teratocarcinoma stem cell surface lectin 1982 Martin GR, Rosen SD, Grabel LB -
A fucan specific lectin on teratocarcinoma stem cells.
Biochemical and biophysical research communications 1981 Grabel LB, Glabe CG, Singer MS, Martin GR, Rosen SD -
Specific rosette formation between fibroblasts and erythrocytes.
Journal of cell science 1981 Rosen SD, Singer MS, Glabe CG, Grabel LB -
Distribution and variation of hemagglutinating activity in the hemolymph of Biomphalaria glabrata.
Journal of invertebrate pathology 1981 Jeong KH, Sussman S, Rosen SD, Lie KJ, Heyneman D -
Purification and characterization of multiple species (isolectins) of a slime mold lectin implicated in intercellular adhesion.
The Journal of biological chemistry 1979 Rosen SD, Kaur J, Clark DL, Pardos BT, Frazier WA -
Teratocarcinoma stem cells have a cell surface carbohydrate-binding component implicated in cell-cell adhesion.
Cell 1979 Grabel LB, Rosen SD, Martin GR -
American Zoologist
Intercellular adhesion in the cellular slime mold 1979 Rosen SD, Kaur J -
Dictyostelium discoideum agglutinins (discoidins I and II).
Methods in enzymology 1978 Barondes SH, Rosen SD, Frazier WA, Simpson DL, Haywood PL -
Polysphondylium pallidum agglutinin (pallidin).
Methods in enzymology 1978 Barondes SH, Simpson DL, Rosen SD, Haywood PL -
Specificity in Embryological Interactions, Garrod DR, editor
Cell adhesion in the cellular slime molds 1978 Rosen SD, Barondes SH -
Intercellular adhesion in the cellular slime mold Polysphondylium pallidum inhibited by interaction of asialofetuin or specific univalent antibody with endogenous cell surface lectin.
Developmental biology 1977 Rosen SD, Chang CM, Barondes SH -
Cell surface location of an endogenous lectin and its receptor in Polysphondylium pallidum.
Experimental cell research 1977 Chang CM, Rosen SD, Barondes SH -
Inhibition of intercellular adhesion in a cellular slime mould by univalent antibody against a cell-surface lectin.
Nature 1976 Rosen SD, Haywood PL, Barondes SH -
Neuronal Recognition, SH Barondes, editor
Cell surface carbohydrate-binding proteins and the mediation of intercellular adhesion 1976 Barondes SH, Rosen SD -
Surface Membrane Receptors, Bradshaw R, Frazier WA, Merrell RC, Gottlieb D, Angeletti R, editors
Multiple lectins in two species of cellular slime molds 1976 Frazier WA, Rosen SD, Reitherman RW, Barondes SH -
Surface Membrane Receptors, Bradshaw R, Frazier WA, Merrell RC, Gottlieb D, Angeletti RA, editors
Cellular recognition in slime molds: evidence for its mediation by cell surface, species-specific lectins and complementary oligosaccharides 1976 Barondes SH, Rosen SD -
Pallidin. Purification and characterization of a carbohydrate-binding protein from Polysphondylium pallidum implicated in intercellular adhesion.
Biochimica et biophysica acta 1975 Simpson DL, Rosen SD, Barondes SH -
Purification and comparison of two developmentally regulated lectins from Dictyostelium discoideum. Discoidin I and II.
The Journal of biological chemistry 1975 Frazier WA, Rosen SD, Reitherman RW, Barondes SH -
Cell surface location of discoidin, a developmentally regulated carbohydrate-binding protein from Dictyostelium discoideum.
Experimental cell research 1975 Chang CM, Reitherman RW, Rosen SD, Barondes SH -
Distinct lectin activities from six species of cellular slime molds.
Experimental cell research 1975 Rosen SD, Reitherman RW, Barondes SH -
Cell surface species-specific high affinity receptors for discoidin: developmental regulation in Dictyostelium discoideum.
Proceedings of the National Academy of Sciences of the United States of America 1975 Reitherman RW, Rosen SD, Frasier WA, Barondes SH -
Carbohydrate-binding protein from Polysphondylium pallidum implicated in intercellular adhesion.
Nature 1974 Rosen SD, Simpson DL, Rose JE, Barondes SH -
Discoidin, a developmentally regulated carbohydrate-binding protein from Dictyostelium discoideum. Purification and characterization.
Biochemistry 1974 Simpson DL, Rosen SD, Barondes SH -
Lectin purification using formalinised erythrocytes as a general affinity adsorbant.
Nature 1974 Reitherman RW, Rosen SD, Barondes SH -
Developmentally regulated, carbohydrate-binding protein in Dictyostelium discoideum.
Proceedings of the National Academy of Sciences of the United States of America 1973 Rosen SD, Kafka JA, Simpson DL, Barondes SH -
Dynamics of Degeneration and Growth in Neurons
Agglutinins of formalinized erythrocytes: changes in activity with development of Dictyostelium discoideum and embryonic chick brain 1973 Barondes SH, Rosen SD, Simpson DL, Kafka JA