Stephen Hulley, MD
Professor Emeritus
Epidemiology & Biostatistics
School of Medicine

Grants and Projects

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• Traineeships in AIDS Prevention Studies, NIH, 1989-2024
• Data Coordinating Center for VEST and PREDICTS, NIH, 2007-2012
• Ucsf Clinical Research Curriculum Award, NIH, 1999-2010
• UCSF: Clinical Research Careers Program (RMI), NIH, 2004-2009
• Multidisciplinary Clinical Research Careers Program(RMI), NIH, 2004-2009
• Clinical Research Training Program, NIH, 1999-2005
• MEDICINE OR SURGERY?(MS?), NIH, 1996-2003
• Center for Aids Prevention Studies (Caps), NIH, 1900-2002
• Preventive Cardiology Academic Award, NIH, 1990-1996
• Hiv Risk and Infection among Alcoholics Seeking Therapy, NIH, 1990-1995
• Dental Clinical Epidemiology Program, NIH, 1987-1994
• Small Instrumentation Grant, NIH, 1991-1992
• Diuretics, Hypertension, and Arrhythmias Clinical Trial, NIH, 1986-1992
• Percutaneous Cardiac Mapping and Ablation Registry, NIH, 1986-1992
• Serum Fatty Acids &Incidence of Coronary Heart Disease, NIH, 1983-1987
• Systolic Hypertension in the Elderly - Ii, NIH, 1980-1987

Publications (55)

Top publication keywords:
Estrogens, Conjugated (USP)Estrogen Replacement TherapyMedroxyprogesterone AcetateCoronary DiseaseThromboembolismHormone Replacement TherapyCoronary Artery DiseaseDefibrillatorsCardiovascular DiseasesHypercholesterolemiaPostmenopauseGuideline AdherenceCalcinosisEstrogensDeath, Sudden, Cardiac

• Impact of wearable cardioverter-defibrillator compliance on outcomes in the VEST trial: As-treated and per-protocol analyses.
  Journal of cardiovascular electrophysiology 2020 Olgin JE, Lee BK, Vittinghoff E, Morin DP, Zweibel S, Rashba E, Chung EH, Borggrefe M, Hulley S, Lin F, Hue TF, Pletcher MJ
• Wearable Cardioverter-Defibrillator after Myocardial Infarction.
  The New England journal of medicine 2018 Olgin JE, Pletcher MJ, Vittinghoff E, Wranicz J, Malik R, Morin DP, Zweibel S, Buxton AE, Elayi CS, Chung EH, Rashba E, Borggrefe M, Hue TF, Maguire C, Lin F, Simon JA, Hulley S, Lee BK, VEST …
• Association of 10-year and lifetime predicted cardiovascular disease risk with subclinical atherosclerosis in South Asians: findings from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study.
  Journal of the American Heart Association 2014 Kandula NR, Kanaya AM, Liu K, Lee JY, Herrington D, Hulley SB, Persell SD, Lloyd-Jones DM, Huffman MD
• Mediators of Atherosclerosis in South Asians Living in America (MASALA) study: objectives, methods, and cohort description.
  Clinical cardiology 2013 Kanaya AM, Kandula N, Herrington D, Budoff MJ, Hulley S, Vittinghoff E, Liu K
• Re: Childhood lipid screening: evidence and conflicts.
  Pediatrics 2013 Newman TB, Pletcher MJ, Hulley SB

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• Overly aggressive new guidelines for lipid screening in children: evidence of a broken process.
  Pediatrics 2012 Newman TB, Pletcher MJ, Hulley SB
• Risk factor and prediction modeling for sudden cardiac death in women with coronary artery disease.
  Archives of internal medicine 2011 Deo R, Vittinghoff E, Lin F, Tseng ZH, Hulley SB, Shlipak MG
• Statin therapy in young adults: ready for prime time?
  Journal of the American College of Cardiology 2010 Pletcher MJ, Hulley SB
• Nonoptimal lipids commonly present in young adults and coronary calcium later in life: the CARDIA (Coronary Artery Risk Development in Young Adults) study.
  Annals of internal medicine 2010 Pletcher MJ, Bibbins-Domingo K, Liu K, Sidney S, Lin F, Vittinghoff E, Hulley SB
• Racial differences in atrial fibrillation prevalence and left atrial size.
  The American journal of medicine 2010 Marcus GM, Olgin JE, Whooley M, Vittinghoff E, Stone KL, Mehra R, Hulley SB, Schiller NB
• Cross-sectional and longitudinal associations between objectively measured sleep duration and body mass index: the CARDIA Sleep Study.
  American journal of epidemiology 2009 Lauderdale DS, Knutson KL, Rathouz PJ, Yan LL, Hulley SB, Liu K
• Postmenopausal hormone treatment.
  JAMA 2009 Hulley S, Grady D
• Association between sleep and blood pressure in midlife: the CARDIA sleep study.
  Archives of internal medicine 2009 Knutson KL, Van Cauter E, Rathouz PJ, Yan LL, Hulley SB, Liu K, Lauderdale DS
• Racial differences in incident heart failure among young adults.
  The New England journal of medicine 2009 Bibbins-Domingo K, Pletcher MJ, Lin F, Vittinghoff E, Gardin JM, Arynchyn A, Lewis CE, Williams OD, Hulley SB
• Prehypertension during young adulthood and coronary calcium later in life.
  Annals of internal medicine 2008 Pletcher MJ, Bibbins-Domingo K, Lewis CE, Wei GS, Sidney S, Carr JJ, Vittinghoff E, McCulloch CE, Hulley SB
• Kidney dysfunction and sudden cardiac death among women with coronary heart disease.
  Hypertension (Dallas, Tex. : 1979) 2008 Deo R, Lin F, Vittinghoff E, Tseng ZH, Hulley SB, Shlipak MG
• Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.
  Heart rhythm 2008 Tseng ZH, Aouizerat BE, Pawlikowska L, Vittinghoff E, Lin F, Whiteman D, Poon A, Herrington D, Howard TD, Varosy PD, Hulley SB, Malloy M, Kane J, Kwok PY, Olgin JE
• Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment.
  Circulation 2008 Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, Saad M, Williams PT, Taylor KD, Yang H, Nickerson DA, Rotter JI
• Early adult risk factor levels and subsequent coronary artery calcification: the CARDIA Study.
  Journal of the American College of Cardiology 2007 Loria CM, Liu K, Lewis CE, Hulley SB, Sidney S, Schreiner PJ, Williams OD, Bild DE, Detrano R
• Marijuana use, diet, body mass index, and cardiovascular risk factors (from the CARDIA study).
  The American journal of cardiology 2006 Rodondi N, Pletcher MJ, Liu K, Hulley SB, Sidney S, Coronary Artery Risk Development in Young Adults (CARDIA) Study
• Objectively measured sleep characteristics among early-middle-aged adults: the CARDIA study.
  American journal of epidemiology 2006 Lauderdale DS, Knutson KL, Yan LL, Rathouz PJ, Hulley SB, Sidney S, Liu K
• Incidence and antecedents of nonmedical prescription opioid use in four US communities. The Coronary Artery Risk Development in Young Adults (CARDIA) prospective cohort study.
  Drug and alcohol dependence 2006 Pletcher MJ, Kertesz SG, Sidney S, Kiefe CI, Hulley SB
• C-reactive protein concentration and incident hypertension in young adults: the CARDIA study.
  Archives of internal medicine 2006 Lakoski SG, Herrington DM, Siscovick DM, Hulley SB
• Randomized trial of medical treatment versus hysterectomy for abnormal uterine bleeding: resource use in the Medicine or Surgery (Ms) trial.
  American journal of obstetrics and gynecology 2006 Showstack J, Lin F, Learman LA, Vittinghoff E, Kuppermann M, Varner RE, Summitt RL, McNeeley SG, Richter H, Hulley S, Washington AE, Ms Research Group
• Phenotypic predictors of response to simvastatin therapy among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study.
  The American journal of cardiology 2006 Simon JA, Lin F, Hulley SB, Blanche PJ, Waters D, Shiboski S, Rotter JI, Nickerson DA, Yang H, Saad M, Krauss RM
• Aspirin use for the primary prevention of coronary heart disease in older adults.
  The American journal of medicine 2005 Rodondi N, Vittinghoff E, Cornuz J, Butler J, Ding J, Satterfield S, Newman AB, Harris TB, Hulley SB, Bauer DC, Health, Aging, and Body Composition Study research group
• Cocaine and coronary calcification in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study.
  American heart journal 2005 Pletcher MJ, Kiefe CI, Sidney S, Carr JJ, Lewis CE, Hulley SB
• Postmenopausal hormone therapy: does it cause incontinence?
  Obstetrics and gynecology 2005 Steinauer JE, Waetjen LE, Vittinghoff E, Subak LL, Hulley SB, Grady D, Lin F, Brown JS
• Sexual activity and function in postmenopausal women with heart disease.
  Obstetrics and gynecology 2005 Addis IB, Ireland CC, Vittinghoff E, Lin F, Stuenkel CA, Hulley S
• Sexual functioning after total compared with supracervical hysterectomy: a randomized trial.
  Obstetrics and gynecology 2005 Kuppermann M, Summitt RL, Varner RE, McNeeley SG, Goodman-Gruen D, Learman LA, Ireland CC, Vittinghoff E, Lin F, Richter HE, Showstack J, Hulley SB, Washington AE, Total or Supracervical Hysterectomy …
• Impaired fasting glucose and cardiovascular outcomes in postmenopausal women with coronary artery disease.
  Annals of internal medicine 2005 Kanaya AM, Herrington D, Vittinghoff E, Lin F, Bittner V, Cauley JA, Hulley S, Barrett-Connor E
• Alcohol consumption, binge drinking, and early coronary calcification: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) Study.
  American journal of epidemiology 2005 Pletcher MJ, Varosy P, Kiefe CI, Lewis CE, Sidney S, Hulley SB
• Causes and demographic, medical, lifestyle and psychosocial predictors of premature mortality: the CARDIA study.
  Social science & medicine (1982) 2005 Iribarren C, Jacobs DR, Kiefe CI, Lewis CE, Matthews KA, Roseman JM, Hulley SB
• Effect of hormone therapy on mortality rates among women with heart failure and coronary artery disease.
  The American journal of cardiology 2005 Bibbins-Domingo K, Lin F, Vittinghoff E, Barrett-Connor E, Hulley SB, Grady D, Shlipak MG
• Predictors of heart failure among women with coronary disease.
  Circulation 2004 Bibbins-Domingo K, Lin F, Vittinghoff E, Barrett-Connor E, Hulley SB, Grady D, Shlipak MG
• Hysterectomy versus expanded medical treatment for abnormal uterine bleeding: clinical outcomes in the medicine or surgery trial.
  Obstetrics and gynecology 2004 Learman LA, Summitt RL, Varner RE, Richter HE, Lin F, Ireland CC, Kuppermann M, Vittinghoff E, Showstack J, Washington AE, Hulley SB, Medicine or Surgery Research Group
• Physical and sexual function in women with chronic kidney disease.
  American journal of kidney diseases : the official journal of the National Kidney Foundation 2004 Kurella M, Ireland C, Hlatky MA, Shlipak MG, Yaffe K, Hulley SB, Chertow GM
• Resource use for total and supracervical hysterectomies: results of a randomized trial.
  Obstetrics and gynecology 2004 Showstack J, Kuppermann M, Lin F, Vittinghoff E, Varner RE, Summitt RL, McNeeley SG, Learman LA, Richter H, Hulley S, Washington AE
• The WHI estrogen-alone trial--do things look any better?
  JAMA 2004 Hulley SB, Grady D
• Effect of hysterectomy vs medical treatment on health-related quality of life and sexual functioning: the medicine or surgery (Ms) randomized trial.
  JAMA 2004 Kuppermann M, Varner RE, Summitt RL, Learman LA, Ireland C, Vittinghoff E, Stewart AL, Lin F, Richter HE, Showstack J, Hulley SB, Washington AE, Ms Research Group
• Relation of ascorbic acid to coronary artery calcium: the Coronary Artery Risk Development in Young Adults Study.
  American journal of epidemiology 2004 Simon JA, Murtaugh MA, Gross MD, Loria CM, Hulley SB, Jacobs DR
• Medicine or Surgery (Ms): a randomized clinical trial comparing hysterectomy and medical treatment in premenopausal women with abnormal uterine bleeding.
  Controlled clinical trials 2004 Varner RE, Ireland CC, Summitt RL, Richter HE, Learman LA, Vittinghoff E, Kuppermann M, Washington E, Hulley SB, Ms Research Group
• Lipid changes on hormone therapy and coronary heart disease events in the Heart and Estrogen/progestin Replacement Study (HERS).
  American heart journal 2003 Shlipak MG, Chaput LA, Vittinghoff E, Lin F, Bittner V, Knopp RH, Hulley SB, Heart and Estrogen/progestin Replacement Study Investigators
• A randomized comparison of total or supracervical hysterectomy: surgical complications and clinical outcomes.
  Obstetrics and gynecology 2003 Learman LA, Summitt RL, Varner RE, McNeeley SG, Goodman-Gruen D, Richter HE, Lin F, Showstack J, Ireland CC, Vittinghoff E, Hulley SB, Washington AE, Total or Supracervical Hysterectomy (TOSH) …
• Fracture and the risk of coronary events in women with heart disease.
  The American journal of medicine 2003 Varosy PD, Shlipak MG, Vittinghoff E, Black DM, Herrington D, Hulley SB, Browner WS, Heart and Estrogen/Progestin Replacement Study(HERS) Investigators
• Positional change in blood pressure and 8-year risk of hypertension: the CARDIA Study.
  Mayo Clinic proceedings 2003 Thomas RJ, Liu K, Jacobs DR, Bild DE, Kiefe CI, Hulley SB
• Risk factors and secondary prevention in women with heart disease: the Heart and Estrogen/progestin Replacement Study.
  Annals of internal medicine 2003 Vittinghoff E, Shlipak MG, Varosy PD, Furberg CD, Ireland CC, Khan SS, Blumenthal R, Barrett-Connor E, Hulley S, Heart and Estrogen/progestin Replacement Study Research Group
• Depressive symptoms, unemployment, and loss of income: The CARDIA Study.
  Archives of internal medicine 2002 Whooley MA, Kiefe CI, Chesney MA, Markovitz JH, Matthews K, Hulley SB, CARDIA Study
• Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II).
  JAMA 2002 Grady D, Herrington D, Bittner V, Blumenthal R, Davidson M, Hlatky M, Hsia J, Hulley S, Herd A, Khan S, Newby LK, Waters D, Vittinghoff E, Wenger N, HERS Research Group
• Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II).
  JAMA 2002 Hulley S, Furberg C, Barrett-Connor E, Cauley J, Grady D, Haskell W, Knopp R, Lowery M, Satterfield S, Schrott H, Vittinghoff E, Hunninghake D, HERS Research Group
• Aircraft cabin air recirculation and symptoms of the common cold.
  JAMA 2002 Zitter JN, Mazonson PD, Miller DP, Hulley SB, Balmes JR
• Factor V Leiden, hormone replacement therapy, and risk of venous thromboembolic events in women with coronary disease.
  Arteriosclerosis, thrombosis, and vascular biology 2002 Herrington DM, Vittinghoff E, Howard TD, Major DA, Owen J, Reboussin DM, Bowden D, Bittner V, Simon JA, Grady D, Hulley SB
• Absence of risk factor change in young adults after family heart attack or stroke: the CARDIA Study.
  American journal of preventive medicine 2002 Kip KE, McCreath HE, Roseman JM, Hulley SB, Schreiner PJ
• Subgroup interactions in the Heart and Estrogen/Progestin Replacement Study: lessons learned.
  Circulation 2002 Furberg CD, Vittinghoff E, Davidson M, Herrington DM, Simon JA, Wenger NK, Hulley S
• Estrogens should not be initiated for the secondary prevention of coronary artery disease: a debate.
  The Canadian journal of cardiology 2000 Hulley S