Stephen Bent, MD
Professor Emeritus
Medicine
School of Medicine

Dr. Bent has also served as the principal investigator or co-investigator of several other large randomized controlled trials, including a study of a Chinese herbal remedy used to treat fatigue in the elderly and an internet-based study examining the efficacy of the herbs valerian (for sleep) and kava (for anxiety). Recently, Dr. Bent has conducted clinical trials of complementary and alternative therapies in children with autism, including studies of omega-3 fatty acids, methyl B12, sulforaphane, and vitamin D. Dr. Bent was also the Principal Investigator of the first-ever fully internet-based randomized controlled trial of a pharmaceutical drug and the first internet-based trial of a treatment (omega-3 fatty acids) conducted in children with autism. He plans to further develop internet-based technology to speed the testing of promising new therapies. Dr. Bent is an expert in evidence-based medicine and ambulatory care, and has coauthored textbooks in both areas.

• Association of Social and Behavioral Risk Factors With Mortality Among US Veterans With COVID-19.
  JAMA network open 2021 Kelly JD, Bravata DM, Bent S, Wray CM, Leonard SJ, Boscardin WJ, Myers LJ, Keyhani S
• A telehealth-based randomized controlled trial: A model for outpatient trials of off-label medications during the COVID-19 pandemic.
  Clinical trials (London, England) 2021 Keyhani S, Kelly JD, Bent S, Boscardin WJ, Shlipak MG, Leonard S, Abraham A, Lum E, Lau N, Austin C, Oldenburg CE, Zillich A, Lopez L, Zhang Y, Lietman T, Bravata DM
• The association between anxiety and academic performance in children with reading disorder: A longitudinal cohort study.
  Dyslexia (Chichester, England) 2021 Hossain B, Bent S, Hendren R
• Feasibility of universal screening for postpartum mood and anxiety disorders among caregivers of infants hospitalized in NICUs: a systematic review.
  Journal of perinatology : official journal of the California Perinatal Association 2021 Murthy S, Haeusslein L, Bent S, Fitelson E, Franck LS, Mangurian C
• Diagnosis of Achilles' Tendon Rupture during a Virtual Examination.
  The New England journal of medicine 2021 Bent S, O'Malley MJ
• Improving Social Knowledge and Skills among Adolescents with Autism: Systematic Review and Meta-Analysis of UCLA PEERS® for Adolescents.
  Journal of autism and developmental disorders 2021 Zheng S, Kim H, Salzman E, Ankenman K, Bent S
• Implementing an established musculoskeletal educational curriculum in a new context: a study of effectiveness and feasibility.
  Medical education online 2020 Pearson M, Barker AM, Battistone MJ, Bent S, Odden K, O'Brien B
• Optimal management of esophageal cancer in Africa: A systemic review of treatment strategies.
  International journal of cancer 2020 Buckle GC, Mahapatra R, Mwachiro M, Akoko L, Mmbaga EJ, White RE, Bent S, Van Loon K
• Quality of Life Among School-Age Children With Autism: The Oak Hill School Outcomes Study.
  Seminars in pediatric neurology 2020 Bent S, Wahlberg J, Chen Y, Widjaja F, McDonald MG, Hendren RL
• Breast Cancer Screening in Women With Schizophrenia: A Systematic Review and Meta-Analysis.
  Psychiatric services (Washington, D.C.) 2019 Hwong A, Wang K, Bent S, Mangurian C
• Population health interventions to improve colorectal cancer screening by fecal immunochemical tests: A systematic review.
  Preventive medicine 2018 Issaka RB, Avila P, Whitaker E, Bent S, Somsouk M
• Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli.
  Molecular autism 2018 Bent S, Lawton B, Warren T, Widjaja F, Dang K, Fahey JW, Cornblatt B, Kinchen JM, Delucchi K, Hendren RL
• Integrating Autism Care through a School-Based Intervention Model: A Pilot Study.
  Journal of clinical medicine 2017 Dang K, Bent S, Lawton B, Warren T, Widjaja F, McDonald MG, Breard M, O'Keefe W, Hendren RL
• Anticoagulation for the treatment of venous thromboembolism in patients with brain metastases: a meta-analysis and systematic review.
  Journal of thrombosis and thrombolysis 2017 Hunter BD, Minichiello T, Bent S
• Open-Label Trial of Vitamin D3 Supplementation in Children with Autism Spectrum Disorder.
  Journal of alternative and complementary medicine (New York, N.Y.) 2017 Bent S, Ailarov A, Dang KT, Widjaja F, Lawton BL, Hendren RL
• Examining Clinics for Children with Autism: The Autism Translating To Treatment Study.
  Journal of alternative and complementary medicine (New York, N.Y.) 2017 Bent S, Dang K, Widjaja F, Lawton B, Nazneen N, Hendren RL
• Randomized, Placebo-Controlled Trial of Methyl B12 for Children with Autism.
  Journal of child and adolescent psychopharmacology 2016 Hendren RL, James SJ, Widjaja F, Lawton B, Rosenblatt A, Bent S
• The Impact of Clinical Decision Rules on Computed Tomography Use and Yield for Pulmonary Embolism: A Systematic Review and Meta-analysis.
  Annals of emergency medicine 2015 Wang RC, Bent S, Weber E, Neilson J, Smith-Bindman R, Fahimi J
• Complementary and alternative treatments for autism part 1: evidence-supported treatments.
  AMA journal of ethics 2015 Bent S, Hendren RL
• Internet-based, randomized, controlled trial of omega-3 fatty acids for hyperactivity in autism.
  Journal of the American Academy of Child and Adolescent Psychiatry 2014 Bent S, Hendren RL, Zandi T, Law K, Choi JE, Widjaja F, Kalb L, Nestle J, Law P
• Brief report: Hyperbaric oxygen therapy (HBOT) in children with autism spectrum disorder: a clinical trial.
  Journal of autism and developmental disorders 2012 Bent S, Bertoglio K, Ashwood P, Nemeth E, Hendren RL
• Procalcitonin-guided antibiotic therapy for chronic obstructive pulmonary disease exacerbations.
  Expert review of anti-infective therapy 2011 Tokman S, Schuetz P, Bent S
• A pilot randomized controlled trial of omega-3 fatty acids for autism spectrum disorder.
  Journal of autism and developmental disorders 2011 Bent S, Bertoglio K, Ashwood P, Bostrom A, Hendren RL
• Improving the prediction of response to therapy in autism.
  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2010 Bent S, Hendren RL
• The impact of a "low-intensity" versus "high-intensity" medical intensive care unit on patient outcomes in critically ill veterans.
  Journal of intensive care medicine 2010 Singer JP, Kohlwes J, Bent S, Zimmerman L, Eisner MD
• Why change is needed in research examining dietary supplements.
  Clinical pharmacology and therapeutics 2010 Tsourounis C, Bent S
• The prognosis and treatment of acquired hemophilia: a systematic review and meta-analysis.
  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2009 Bitting RL, Bent S, Li Y, Kohlwes J
• Gender as a risk factor for advanced neoplasia and colorectal cancer: a systematic review and meta-analysis.
  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2009 Nguyen SP, Bent S, Chen YH, Terdiman JP
• Antibiotic and anti-inflammatory use and the risk of prostate cancer.
  BMC research notes 2009 Daniels NA, Chen YH, Bent S
• Omega-3 fatty acids for autistic spectrum disorder: a systematic review.
  Journal of autism and developmental disorders 2009 Bent S, Bertoglio K, Hendren RL
• The relation of alpha-linolenic acid to the risk of prostate cancer: a systematic review and meta-analysis.
  The American journal of clinical nutrition 2009 Simon JA, Chen YH, Bent S
• Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarin.
  Journal of general internal medicine 2009 Kangelaris KN, Bent S, Nussbaum RL, Garcia DA, Tice JA
• Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical Center.
  Journal of general internal medicine 2008 Bent S
• Initial experience with a group presentation of study results to research participants.
  Trials 2008 Avins AL, Bent S, Padula A, Staccone S, Badua E, Goldberg H
• A detailed safety assessment of a saw palmetto extract.
  Complementary therapies in medicine 2008 Avins AL, Bent S, Staccone S, Badua E, Padula A, Goldberg H, Neuhaus J, Hudes E, Shinohara K, Kane C
• Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysis.
  The American journal of medicine 2007 Li JZ, Winston LG, Moore DH, Bent S
• Does this adult patient have septic arthritis?
  JAMA 2007 Margaretten ME, Kohlwes J, Moore D, Bent S
• Valerian for sleep: a systematic review and meta-analysis.
  The American journal of medicine 2006 Bent S, Padula A, Moore D, Patterson M, Mehling W
• Saw palmetto and lower urinary tract symptoms: what is the latest evidence?
  Current urology reports 2006 Avins AL, Bent S
• The PRIME curriculum. Clinical research training during residency.
  Journal of general internal medicine 2006 Kohlwes RJ, Shunk RL, Avins A, Garber J, Bent S, Shlipak MG
• Brief communication: Better ways to question patients about adverse medical events: a randomized, controlled trial.
  Annals of internal medicine 2006 Bent S, Padula A, Avins AL
• Saw palmetto for benign prostatic hyperplasia.
  The New England journal of medicine 2006 Bent S, Kane C, Shinohara K, Neuhaus J, Hudes ES, Goldberg H, Avins AL
• An internet-based randomized, placebo-controlled trial of kava and valerian for anxiety and insomnia.
  Medicine 2005 Jacobs BP, Bent S, Tice JA, Blackwell T, Cummings SR
• Spontaneous bleeding associated with ginkgo biloba: a case report and systematic review of the literature: a case report and systematic review of the literature.
  Journal of general internal medicine 2005 Bent S, Goldberg H, Padula A, Avins AL
• Use of an embedded N-of-1 trial to improve adherence and increase information from a clinical study.
  Contemporary clinical trials 2005 Avins AL, Bent S, Neuhaus JM
• N-acetylcysteine for the prevention of contrast-induced nephropathy. A systematic review and meta-analysis.
  Journal of general internal medicine 2005 Liu R, Nair D, Ix J, Moore DH, Bent S
• Safety and efficacy of citrus aurantium for weight loss.
  The American journal of cardiology 2004 Bent S, Padula A, Neuhaus J
• Systematic review: computed tomography and ultrasonography to detect acute appendicitis in adults and adolescents.
  Annals of internal medicine 2004 Terasawa T, Blackmore CC, Bent S, Kohlwes RJ
• The use of systematic reviews and meta-analyses in infection control and hospital epidemiology.
  American journal of infection control 2004 Bent S, Shojania KG, Saint S
• Commonly used herbal medicines in the United States: a review.
  The American journal of medicine 2004 Bent S, Ko R
• A randomized controlled trial of a Chinese herbal remedy to increase energy, memory, sexual function, and quality of life in elderly adults in Beijing, China.
  The American journal of medicine 2003 Bent S, Xu L, Lui LY, Nevitt M, Schneider E, Tian G, Guo S, Cummings S
• Test characteristics of alpha-fetoprotein for detecting hepatocellular carcinoma in patients with hepatitis C. A systematic review and critical analysis.
  Annals of internal medicine 2003 Gupta S, Bent S, Kohlwes J
• The relative safety of ephedra compared with other herbal products.
  Annals of internal medicine 2003 Bent S, Tiedt TN, Odden MC, Shlipak MG
• The optimal use of diagnostic testing in women with acute uncomplicated cystitis.
  The American journal of medicine 2002 Bent S, Saint S
• Does this woman have an acute uncomplicated urinary tract infection?
  JAMA 2002 Bent S, Nallamothu BK, Simel DL, Fihn SD, Saint S
• An evidence-based review of the 10 most commonly used herbs.
  The Western journal of medicine 1999 Mar C, Bent S
• Antibiotics in acute bronchitis: a meta-analysis.
  The American journal of medicine 1999 Bent S, Saint S, Vittinghoff E, Grady D
• Commentary: Adulterants in herbal products: dangerous and deceitful.
  The Western journal of medicine 1999 Bent S
• Antibiotics in chronic obstructive pulmonary disease exacerbations. A meta-analysis.
  JAMA 1995 Saint S, Bent S, Vittinghoff E, Grady D