Stathis Gennatas, MBBS, PhD
Assistant Professor
Epidemiology & Biostatistics
School of Medicine

Education & Training

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• Diversity, Equity, and Inclusion Champion Training University of California 2022
• PhD Neuroscience University of Pennsylvania 06/2017
• MBBS Medicine Imperial College London 06/2008

Interests

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• Psychiatry
• Neuroimaging
• software design
• machine learning
• imaging informatics
• Biomedical Informatics
• Neurology
• clinical informatics
• data science
• Precision Medicine
• clinical decision support
• big data
• data visualization
• artificial intelligence

Websites

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• Lab Site (lambdamd.org)
• rtemis Machine Learning (rtemis.org)

Publications (44)

Top publication keywords:
Medical InformaticsBlindnessAirway ExtubationAlgorithmsVisual PathwaysMeningiomaElectronic Health RecordsAcute-On-Chronic Liver FailureExpert SystemsGray MatterCatechol O-MethyltransferasePostoperative CareMachine LearningPreoperative CareIntensive Care Units, Pediatric

• A Trypanosoma cruzi trans-sialidase peptide demonstrates high serological prevalence among infected populations across endemic regions.
  The Journal of clinical investigation 2026 Kortbawi HM, Marczak RJ, Rajan JV, Bulaong NL, Pak JE, Wu W, Wang G, Mitchell A, Saxena A, Maheshwari A, Leone RA, Fleischmann CJ, Kelly EA, Teal E, Townsend RL, Stramer SL, Okamoto EE, Sherbuk JE, …
• Methods for Addressing Missingness in Electronic Health Record Data for Clinical Prediction Models: Comparative Evaluation.
  JMIR medical informatics 2025 Digitale J, Franzon D, Pletcher MJ, McCulloch CE, Gennatas ED
• Expert-augmented machine learning for predicting extubation readiness in the pediatric intensive care unit.
  BMC medical informatics and decision making 2025 Digitale J, Franzon D, Ge J, McCulloch C, Pletcher MJ, Gennatas ED
• A Trypanosoma cruzi Trans-Sialidase Peptide Demonstrates High Serological Prevalence Among Infected Populations Across Endemic Regions of Latin America.
  medRxiv : the preprint server for health sciences 2025 Kortbawi HM, Marczak RJ, Rajan JV, Bulaong NL, Pak JE, Wu W, Wang G, Mitchell A, Saxena A, Maheshwari A, Fleischmann CJ, Kelly EA, Teal E, Townsend RL, Stramer SL, Okamoto EE, Sherbuk JE, Clark EH, …
• Tumor Morphology for Prediction of Poor Responses Early in Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter Retrospective Study.
  Tomography (Ann Arbor, Mich.) 2024 Li W, Le NN, Nadkarni R, Onishi N, Wilmes LJ, Gibbs JE, Price ER, Joe BN, Mukhtar RA, Gennatas ED, Kornak J, Magbanua MJM, Van't Veer LJ, LeStage B, Esserman LJ, Hylton NM

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• Development and Validation of Prediction Models for the Diagnosis of Autism Spectrum Disorder in a Korean General Population.
  JAACAP open 2024 Kim H, Leventhal BL, Koh YJ, Gennatas ED, Kim YS
• Gray matter correlates of attention-deficit hyperactivity disorder in boys versus girls with sensory processing dysfunction.
  Imaging neuroscience (Cambridge, Mass.) 2024 Gennatas ED, Wren-Jarvis J, Powers R, Lazerwitz MC, Bourla I, Cai LT, Choi HL, Chu R, Trimarchi KJ, Garcia RD, Marco EJ, Mukherjee P
• Predicting the Effect of Proton Beam Therapy Technology on Pulmonary Toxicities for Patients With Locally Advanced Lung Cancer Enrolled in the Proton Collaborative Group Prospective Clinical Trial.
  International journal of radiation oncology, biology, physics 2023 Valdes G, Scholey J, Nano TF, Gennatas ED, Mohindra P, Mohammed N, Zeng J, Kotecha R, Rosen LR, Chang J, Tsai HK, Urbanic JJ, Vargas CE, Yu NY, Ungar LH, Eaton E, Simone CB
• Predictors of All-Cause 30-Day Readmissions in Patients with Heart Failure at an Urban Safety Net Hospital: The Importance of Social Determinants of Health and Mental Health.
  American journal of medicine open 2023 Steverson AB, Marano PJ, Chen C, Ma Y, Stern RJ, Feng J, Gennatas ED, Marks JD, Durstenfeld MS, Davis JD, Hsue PY, Zier LS
• Predicting post-liver transplant outcomes in patients with acute-on-chronic liver failure using Expert-Augmented Machine Learning.
  American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2023 Ge J, Digitale JC, Fenton C, McCulloch CE, Lai JC, Pletcher MJ, Gennatas ED
• Association of SARS-CoV-2 nucleocapsid viral antigen and the receptor for advanced glycation end products with development of severe disease in patients presenting to the emergency department with COVID-19.
  Frontiers in immunology 2023 Matthay ZA, Fields AT, Wick KD, Jones C, Lane HC, Herrera K, Nuñez-Garcia B, Gennatas E, Hendrickson CM, Kornblith AE, Matthay MA, Kornblith LZ, COVID-19 Associated Coagulopathy Inflammation …
• Representational Gradient Boosting: Backpropagation in the Space of Functions.
  IEEE transactions on pattern analysis and machine intelligence 2022 Valdes G, Friedman JH, Jiang F, Gennatas ED
• The Conditional Super Learner.
  IEEE transactions on pattern analysis and machine intelligence 2022 Valdes G, Interian Y, Gennatas E, Van der Laan M
• Underinsurance And Multiple Surgical Treatments for Kidney Stones.
  Urology 2022 Bayne D, Hicks CR, Srirangapatanam S, Armas-Phan M, Maru J, Gennatas E, Allen IE, Seligman H, Stoller M, Suskind A, Chi TL
• Serine, N-acetylaspartate differentiate adolescents with juvenile idiopathic arthritis compared with healthy controls: a metabolomics cross-sectional study.
  Pediatric rheumatology online journal 2022 Lewis KA, Osier N, Carrasco R, Chiou J, Carter P, Garcia A, Flowers E, Gennatas ED, Nguyen C, Rana A, Brown SA, Tiziani S
• Effectiveness of Adding a Mask Recommendation to Other Public Health Measures.
  Annals of internal medicine 2021 Spinelli MA, Glidden DV, Gennatas ED, Rutherford GW, Gandhi M
• Importance of non-pharmaceutical interventions in lowering the viral inoculum to reduce susceptibility to infection by SARS-CoV-2 and potentially disease severity.
  The Lancet. Infectious diseases 2021 Spinelli MA, Glidden DV, Gennatas ED, Bielecki M, Beyrer C, Rutherford G, Chambers H, Goosby E, Gandhi M
• Structural and Functional Brain Parameters Related to Cognitive Performance Across Development: Replication and Extension of the Parieto-Frontal Integration Theory in a Single Sample.
  Cerebral cortex (New York, N.Y. : 1991) 2021 Gur RC, Butler ER, Moore TM, Rosen AFG, Ruparel K, Satterthwaite TD, Roalf DR, Gennatas ED, Bilker WB, Shinohara RT, Port A, Elliott MA, Verma R, Davatzikos C, Wolf DH, Detre JA, Gur RE
• Reply to Nock and Nielsen: On the work of Nock and Nielsen and its relationship to the additive tree.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Valdes G, Luna JM, Gennatas ED, Ungar LH, Eaton E, Diffenderfer ES, Jensen ST, Simone CB, Friedman JH, Solberg TD
• Expert-augmented machine learning.
  Proceedings of the National Academy of Sciences of the United States of America 2020 Gennatas ED, Friedman JH, Ungar LH, Pirracchio R, Eaton E, Reichmann LG, Interian Y, Luna JM, Simone CB, Auerbach A, Delgado E, van der Laan MJ, Solberg TD, Valdes G
• Building more accurate decision trees with the additive tree.
  Proceedings of the National Academy of Sciences of the United States of America 2019 Luna JM, Gennatas ED, Ungar LH, Eaton E, Diffenderfer ES, Jensen ST, Simone CB, Friedman JH, Solberg TD, Valdes G
• Integrated models incorporating radiologic and radiomic features predict meningioma grade, local failure, and overall survival.
  Neuro-oncology advances 2019 Morin O, Chen WC, Nassiri F, Susko M, Magill ST, Vasudevan HN, Wu A, Vallières M, Gennatas ED, Valdes G, Pekmezci M, Alcaide-Leon P, Choudhury A, Interian Y, Mortezavi S, Turgutlu K, Bush NAO, Solberg…
• Dopamine receptor D4 (DRD4) polymorphisms with reduced functional potency intensify atrophy in syndrome-specific sites of frontotemporal dementia.
  NeuroImage. Clinical 2019 Butler PM, Chiong W, Perry DC, Miller ZA, Gennatas ED, Brown JA, Pasquini L, Karydas A, Dokuru D, Coppola G, Sturm VE, Boxer AL, Gorno-Tempini ML, Rosen HJ, Kramer JH, Miller BL, Seeley WW
• Preoperative and postoperative prediction of long-term meningioma outcomes.
  PloS one 2018 Gennatas ED, Wu A, Braunstein SE, Morin O, Chen WC, Magill ST, Gopinath C, Villaneueva-Meyer JE, Perry A, McDermott MW, Solberg TD, Valdes G, Raleigh DR
• Deep nets vs expert designed features in medical physics: An IMRT QA case study.
  Medical physics 2018 Interian Y, Rideout V, Kearney VP, Gennatas E, Morin O, Cheung J, Solberg T, Valdes G
• Quantitative assessment of structural image quality.
  NeuroImage 2017 Rosen AFG, Roalf DR, Ruparel K, Blake J, Seelaus K, Villa LP, Ciric R, Cook PA, Davatzikos C, Elliott MA, Garcia de La Garza A, Gennatas ED, Quarmley M, Schmitt JE, Shinohara RT, Tisdall MD, Craddock …
• Sex differences in estimated brain metabolism in relation to body growth through adolescence.
  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2017 Vandekar SN, Shou H, Satterthwaite TD, Shinohara RT, Merikangas AK, Roalf DR, Ruparel K, Rosen A, Gennatas ED, Elliott MA, Davatzikos C, Gur RC, Gur RE, Detre JA
• Age-Related Effects and Sex Differences in Gray Matter Density, Volume, Mass, and Cortical Thickness from Childhood to Young Adulthood.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Gennatas ED, Avants BB, Wolf DH, Satterthwaite TD, Ruparel K, Ciric R, Hakonarson H, Gur RE, Gur RC
• Patterns of Individual Variation in Visual Pathway Structure and Function in the Sighted and Blind.
  PloS one 2016 Aguirre GK, Datta R, Benson NC, Prasad S, Jacobson SG, Cideciyan AV, Bridge H, Watkins KE, Butt OH, Dain AS, Brandes L, Gennatas ED
• Elevated Amygdala Perfusion Mediates Developmental Sex Differences in Trait Anxiety.
  Biological psychiatry 2016 Kaczkurkin AN, Moore TM, Ruparel K, Ciric R, Calkins ME, Shinohara RT, Elliott MA, Hopson R, Roalf DR, Vandekar SN, Gennatas ED, Wolf DH, Scott JC, Pine DS, Leibenluft E, Detre JA, Foa EB, Gur RE, Gur…
• Dominant hemisphere lateralization of cortical parasympathetic control as revealed by frontotemporal dementia.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Guo CC, Sturm VE, Zhou J, Gennatas ED, Trujillo AJ, Hua AY, Crawford R, Stables L, Kramer JH, Rankin K, Levenson RW, Rosen HJ, Miller BL, Seeley WW
• Common and Dissociable Mechanisms of Executive System Dysfunction Across Psychiatric Disorders in Youth.
  The American journal of psychiatry 2016 Shanmugan S, Wolf DH, Calkins ME, Moore TM, Ruparel K, Hopson RD, Vandekar SN, Roalf DR, Elliott MA, Jackson C, Gennatas ED, Leibenluft E, Pine DS, Shinohara RT, Hakonarson H, Gur RC, Gur RE, …
• The impact of quality assurance assessment on diffusion tensor imaging outcomes in a large-scale population-based cohort.
  NeuroImage 2015 Roalf DR, Quarmley M, Elliott MA, Satterthwaite TD, Vandekar SN, Ruparel K, Gennatas ED, Calkins ME, Moore TM, Hopson R, Prabhakaran K, Jackson CT, Verma R, Hakonarson H, Gur RC, Gur RE
• Connectome-wide network analysis of youth with Psychosis-Spectrum symptoms.
  Molecular psychiatry 2015 Satterthwaite TD, Vandekar SN, Wolf DH, Bassett DS, Ruparel K, Shehzad Z, Craddock RC, Shinohara RT, Moore TM, Gennatas ED, Jackson C, Roalf DR, Milham MP, Calkins ME, Hakonarson H, Gur RC, Gur RE
• Impact of puberty on the evolution of cerebral perfusion during adolescence.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Satterthwaite TD, Shinohara RT, Wolf DH, Hopson RD, Elliott MA, Vandekar SN, Ruparel K, Calkins ME, Roalf DR, Gennatas ED, Jackson C, Erus G, Prabhakaran K, Davatzikos C, Detre JA, Hakonarson H, Gur …
• Linked Sex Differences in Cognition and Functional Connectivity in Youth.
  Cerebral cortex (New York, N.Y. : 1991) 2014 Satterthwaite TD, Wolf DH, Roalf DR, Ruparel K, Erus G, Vandekar S, Gennatas ED, Elliott MA, Smith A, Hakonarson H, Verma R, Davatzikos C, Gur RE, Gur RC
• Functional maturation of the executive system during adolescence.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Satterthwaite TD, Wolf DH, Erus G, Ruparel K, Elliott MA, Gennatas ED, Hopson R, Jackson C, Prabhakaran K, Bilker WB, Calkins ME, Loughead J, Smith A, Roalf DR, Hakonarson H, Verma R, Davatzikos C, …
• Heterogeneous impact of motion on fundamental patterns of developmental changes in functional connectivity during youth.
  NeuroImage 2013 Satterthwaite TD, Wolf DH, Ruparel K, Erus G, Elliott MA, Eickhoff SB, Gennatas ED, Jackson C, Prabhakaran K, Smith A, Hakonarson H, Verma R, Davatzikos C, Gur RE, Gur RC
• Intrinsic connectivity network disruption in progressive supranuclear palsy.
  Annals of neurology 2013 Gardner RC, Boxer AL, Trujillo A, Mirsky JB, Guo CC, Gennatas ED, Heuer HW, Fine E, Zhou J, Kramer JH, Miller BL, Seeley WW
• COMT Val158Met genotype influences neurodegeneration within dopamine-innervated brain structures.
  Neurology 2012 Gennatas ED, Cholfin JA, Zhou J, Crawford RK, Sasaki DA, Karydas A, Boxer AL, Bonasera SJ, Rankin KP, Gorno-Tempini ML, Rosen HJ, Kramer JH, Weiner M, Miller BL, Seeley WW
• Predicting regional neurodegeneration from the healthy brain functional connectome.
  Neuron 2012 Zhou J, Gennatas ED, Kramer JH, Miller BL, Seeley WW
• TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia.
  Neurology 2010 Rohrer JD, Geser F, Zhou J, Gennatas ED, Sidhu M, Trojanowski JQ, Dearmond SJ, Miller BL, Seeley WW
• Network-level structural covariance in the developing brain.
  Proceedings of the National Academy of Sciences of the United States of America 2010 Zielinski BA, Gennatas ED, Zhou J, Seeley WW
• Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease.
  Brain : a journal of neurology 2010 Zhou J, Greicius MD, Gennatas ED, Growdon ME, Jang JY, Rabinovici GD, Kramer JH, Weiner M, Miller BL, Seeley WW