Stanley Prusiner, MD
Professor
Neurology
School of Medicine

Dr. Prusiner’s contributions to scientific research have been internationally recognized with numerous prizes including the Richard Lounsbery Award, the Albert Lasker Award and the Nobel Prize.

Editor of 11 books and more than 500 research articles, Dr. Prusiner holds 50 issued or allowed United States patents, all of which are assigned to the University of California.

He is a member of the National Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences and the American Philosophical Society, and is a foreign member of the Royal Society, London

Dr. Prusiner received his undergraduate and medical training at the University of Pennsylvania and his postgraduate clinical training at UCSF.

• Viroids, Satellite RNAs and Prions: Folding of Nucleic Acids and Misfolding of Proteins.
  Viruses 2024 Steger G, Riesner D, Prusiner SB
• Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments.
  Nature communications 2023 Merz GE, Chalkley MJ, Tan SK, Tse E, Lee J, Prusiner SB, Paras NA, DeGrado WF, Southworth DR
• Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions.
  Proceedings of the National Academy of Sciences of the United States of America 2023 Condello C, Ayers JI, Dalgard CL, Garcia Garcia MM, Rivera BM, Seeley WW, Perl DP, Prusiner SB
• Aβ and Tau Prions Causing Alzheimer's Disease.
  Methods in molecular biology (Clifton, N.J.) 2023 Condello C, Merz GE, Aoyagi A, DeGrado WF, Prusiner SB
• Aβ and tau prions feature in the neuropathogenesis of Down syndrome.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Condello C, Maxwell AM, Castillo E, Aoyagi A, Graff C, Ingelsson M, Lannfelt L, Bird TD, Keene CD, Seeley WW, Perl DP, Head E, Prusiner SB
• Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein.
  Acta neuropathologica 2022 Holec SAM, Lee J, Oehler A, Ooi FK, Mordes DA, Olson SH, Prusiner SB, Woerman AL
• Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics.
  Nature machine intelligence 2022 Wong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJ
• Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy.
  Proceedings of the National Academy of Sciences of the United States of America 2022 Ayers JI, Lee J, Monteiro O, Woerman AL, Lazar AA, Condello C, Paras NA, Prusiner SB
• How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders.
  International journal of molecular sciences 2021 Carlson GA, Prusiner SB
• Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent.
  Organic letters 2021 Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J
• Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components.
  Neuron 2021 Lester E, Ooi FK, Bakkar N, Ayers J, Woerman AL, Wheeler J, Bowser R, Carlson GA, Prusiner SB, Parker R
• Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles.
  ACS omega 2021 Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J
• Prion biology: implications for Alzheimer's disease therapeutics.
  The Lancet. Neurology 2020 Condello C, DeGrado WF, Prusiner SB
• Expanding spectrum of prion diseases.
  Emerging topics in life sciences 2020 Ayers JI, Paras NA, Prusiner SB
• Prion protein - mediator of toxicity in multiple proteinopathies.
  Nature reviews. Neurology 2020 Ayers JI, Prusiner SB
• Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy.
  PLoS pathogens 2020 Woerman AL, Patel S, Kazmi SA, Oehler A, Lee J, Mordes DA, Olson SH, Prusiner SB
• Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.
  ACS medicinal chemistry letters 2020 Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras…
• Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein.
  Acta neuropathologica communications 2019 Krejciova Z, Carlson GA, Giles K, Prusiner SB
• Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain.
  Science translational medicine 2019 Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, DeGrado WF, Prusiner SB
• Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines.
  Acta neuropathologica 2019 Woerman AL, Oehler A, Kazmi SA, Lee J, Halliday GM, Middleton LT, Gentleman SM, Mordes DA, Spina S, Grinberg LT, Olson SH, Prusiner SB
• α-Synuclein: Multiple System Atrophy Prions.
  Cold Spring Harbor perspectives in medicine 2018 Woerman AL, Watts JC, Aoyagi A, Giles K, Middleton LT, Prusiner SB
• Citations must default to the online publication date.
  Nature 2018 Keller M, Prusiner S
• β-Amyloid Prions and the Pathobiology of Alzheimer's Disease.
  Cold Spring Harbor perspectives in medicine 2018 Watts JC, Prusiner SB
• A long-lived Aβ oligomer resistant to fibrillization.
  Biopolymers 2018 Nick M, Wu Y, Schmidt NW, Prusiner SB, Stöhr J, DeGrado WF
• Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.
  Proceedings of the National Academy of Sciences of the United States of America 2018 Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB
• Familial Parkinson's point mutation abolishes multiple system atrophy prion replication.
  Proceedings of the National Academy of Sciences of the United States of America 2017 Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB
• Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 2017 Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB
• Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines.
  JAMA neurology 2017 Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB
• A novel vector for transgenesis in the rat CNS.
  Acta neuropathologica communications 2017 Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB
• Experimental Models of Inherited PrP Prion Diseases.
  Cold Spring Harbor perspectives in medicine 2017 Watts JC, Prusiner SB
• MSA prions exhibit remarkable stability and resistance to inactivation.
  Acta neuropathologica 2017 Woerman AL, Kazmi SA, Patel S, Freyman Y, Oehler A, Aoyagi A, Mordes DA, Halliday GM, Middleton LT, Gentleman SM, Olson SH, Prusiner SB
• Bioassays and Inactivation of Prions.
  Cold Spring Harbor perspectives in biology 2017 Giles K, Woerman AL, Berry DB, Prusiner SB
• A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
  Nature chemistry 2017 Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF
• Developing Therapeutics for PrP Prion Diseases.
  Cold Spring Harbor perspectives in medicine 2017 Giles K, Olson SH, Prusiner SB
• Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB
• Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.
  Journal of virology 2016 Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB
• Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study.
  Journal of the American Chemical Society 2016 Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stöhr J, Hong M
• FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice.
  Proceedings of the National Academy of Sciences of the United States of America 2016 Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M
• Towards authentic transgenic mouse models of heritable PrP prion diseases.
  Acta neuropathologica 2016 Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB
• Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.
  The Journal of pharmacology and experimental therapeutics 2016 Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB
• Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism.
  Proceedings of the National Academy of Sciences of the United States of America 2015 Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, Grinberg LT, Giles K
• Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation.
  Annals of neurology 2015 Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB
• Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering.
  Biophysical journal 2015 Carter L, Kim SJ, Schneidman-Duhovny D, Stöhr J, Poncet-Montange G, Weiss TM, Tsuruta H, Prusiner SB, Sali A
• Propagation of prions causing synucleinopathies in cultured cells.
  Proceedings of the National Academy of Sciences of the United States of America 2015 Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K…
• Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
  The Journal of pharmacology and experimental therapeutics 2015 Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB
• Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice.
  The Journal of infectious diseases 2015 Berry D, Giles K, Oehler A, Bhardwaj S, DeArmond SJ, Prusiner SB
• Structural studies of truncated forms of the prion protein PrP.
  Biophysical journal 2015 Wan W, Wille H, Stöhr J, Kendall A, Bian W, McDonald M, Tiggelaar S, Watts JC, Prusiner SB, Stubbs G
• Mechanism of scrapie prion precipitation with phosphotungstate anions.
  ACS chemical biology 2015 Levine DJ, Stöhr J, Falese LE, Ollesch J, Wille H, Prusiner SB, Long JR
• Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB
• Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients.
  Proceedings of the National Academy of Sciences of the United States of America 2014 Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB
• Mouse models for studying the formation and propagation of prions.
  The Journal of biological chemistry 2014 Watts JC, Prusiner SB
• Evidence that bank vole PrP is a universal acceptor for prions.
  PLoS pathogens 2014 Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB
• Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells.
  Bioorganic & medicinal chemistry 2014 Silber BM, Gever JR, Rao S, Li Z, Renslo AR, Widjaja K, Wong C, Giles K, Freyman Y, Elepano M, Irwin JJ, Jacobson MP, Prusiner SB
• Transmission of multiple system atrophy prions to transgenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, DeArmond SJ, Prusiner SB
• Drug resistance confounding prion therapeutics.
  Proceedings of the National Academy of Sciences of the United States of America 2013 Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K
• Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease.
  Neurology 2013 Geschwind MD, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, Possin KL, Dearmond SJ, Prusiner…
• Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells.
  Bioorganic & medicinal chemistry 2013 Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB
• A high-throughput screening assay for determining cellular levels of total tau protein.
  Current Alzheimer research 2013 Dehdashti SJ, Zheng W, Gever JR, Wilhelm R, Nguyen DT, Sittampalam G, McKew JC, Austin CP, Prusiner SB
• Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice.
  The Journal of pharmacology and experimental therapeutics 2013 Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB
• Optimization of Arylamides as Novel, Potent and Brain-penetrant Antiprion Lead Compounds.
  ACS medicinal chemistry letters 2013 Li Z, Rao S, Gever JR, Widjaja K, Prusiner SB, Silber BM
• Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo.
  Neurobiology of aging 2013 Godsave SF, Wille H, Pierson J, Prusiner SB, Peters PJ
• Discovery and Preliminary SAR of Arylpiperazines as Novel, Brainpenetrant Antiprion Compounds.
  ACS medicinal chemistry letters 2013 Li Z, Gever J, Rao S, Widjaja K, Prusiner SB, Silber BM
• 2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease.
  ChemMedChem 2013 Li Z, Silber BM, Rao S, Gever JR, Bryant C, Gallardo-Godoy A, Dolghih E, Widjaja K, Elepano M, Jacobson MP, Prusiner SB, Renslo AR
• Convergent replication of mouse synthetic prion strains.
  The American journal of pathology 2013 Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB
• Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice.
  Pharmaceutical research 2013 Silber BM, Rao S, Fife KL, Gallardo-Godoy A, Renslo AR, Dalvie DK, Giles K, Freyman Y, Elepano M, Gever JR, Li Z, Jacobson MP, Huang Y, Benet LZ, Prusiner SB
• Biology and genetics of prions causing neurodegeneration.
  Annual review of genetics 2013 Prusiner SB
• Chimeric elk/mouse prion proteins in transgenic mice.
  The Journal of general virology 2012 Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB
• Novel epitopes identified by anti-PrP monoclonal antibodies produced following immunization of Prnp0/0 Balb/cJ mice with purified scrapie prions.
  Hybridoma (2005) 2012 Stanker LH, Scotcher MC, Lin A, McGarvey J, Prusiner SB, Hnasko R
• Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter.
  PloS one 2012 Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB
• Cell biology. A unifying role for prions in neurodegenerative diseases.
  Science (New York, N.Y.) 2012 Prusiner SB
• Purified and synthetic Alzheimer's amyloid beta (Aβ) prions.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K
• Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold.
  Biophysical journal 2012 Wan W, Wille H, Stöhr J, Baxa U, Prusiner SB, Stubbs G
• Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling.
  Analytical chemistry 2012 Guan S, Price JC, Ghaemmaghami S, Prusiner SB, Burlingame AL
• Identification of I137M and other mutations that modulate incubation periods for two human prion strains.
  Journal of virology 2012 Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB
• Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 2012 Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB
• Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.
  Molecular therapy. Nucleic acids 2012 Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB
• Salivary prions in sheep and deer.
  Prion 2012 Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB
• Prion uptake in the gut: identification of the first uptake and replication sites.
  PLoS pathogens 2011 Kujala P, Raymond CR, Romeijn M, Godsave SF, van Kasteren SI, Wille H, Prusiner SB, Mabbott NA, Peters PJ
• Spontaneous generation of anchorless prions in transgenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K
• Protease-resistant prions selectively decrease Shadoo protein.
  PLoS pathogens 2011 Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB
• De novo generation of prion strains.
  Nature reviews. Microbiology 2011 Colby DW, Prusiner SB
• A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling.
  Molecular & cellular proteomics : MCP 2011 Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL
• Conformational transformation and selection of synthetic prion strains.
  Journal of molecular biology 2011 Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB
• Conserved properties of human and bovine prion strains on transmission to guinea pigs.
  Laboratory investigation; a journal of technical methods and pathology 2011 Safar JG, Giles K, Lessard P, Letessier F, Patel S, Serban A, Dearmond SJ, Prusiner SB
• A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets.
  The Journal of biological chemistry 2011 Poncet-Montange G, St Martin SJ, Bogatova OV, Prusiner SB, Shoichet BK, Ghaemmaghami S
• Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease.
  Proceedings of the National Academy of Sciences of the United States of America 2011 Watts JC, Giles K, Grillo SK, Lemus A, DeArmond SJ, Prusiner SB
• 2-Aminothiazoles as therapeutic leads for prion diseases.
  Journal of medicinal chemistry 2011 Gallardo-Godoy A, Gever J, Fife KL, Silber BM, Prusiner SB, Renslo AR
• Prions.
  Cold Spring Harbor perspectives in biology 2011 Colby DW, Prusiner SB
• Analysis of proteome dynamics in the mouse brain.
  Proceedings of the National Academy of Sciences of the United States of America 2010 Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S
• Human prion strain selection in transgenic mice.
  Annals of neurology 2010 Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB
• Conformation-dependent high-affinity monoclonal antibodies to prion proteins.
  Journal of immunology (Baltimore, Md. : 1950) 2010 Stanker LH, Serban AV, Cleveland E, Hnasko R, Lemus A, Safar J, DeArmond SJ, Prusiner SB
• Colloid formation by drugs in simulated intestinal fluid.
  Journal of medicinal chemistry 2010 Doak AK, Wille H, Prusiner SB, Shoichet BK
• Generation of antisera to purified prions in lipid rafts.
  Prion 2010 Hnasko R, Serban AV, Carlson G, Prusiner SB, Stanker LH
• Protease-sensitive synthetic prions.
  PLoS pathogens 2010 Colby DW, Wain R, Baskakov IV, Legname G, Palmer CG, Nguyen HO, Lemus A, Cohen FE, DeArmond SJ, Prusiner SB
• Discovery of 2-aminothiazoles as potent antiprion compounds.
  Journal of virology 2009 Ghaemmaghami S, May BC, Renslo AR, Prusiner SB
• Chemical induction of misfolded prion protein conformers in cell culture.
  The Journal of biological chemistry 2009 Ghaemmaghami S, Ullman J, Ahn M, St Martin S, Prusiner SB
• Continuous quinacrine treatment results in the formation of drug-resistant prions.
  PLoS pathogens 2009 Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB
• Design and construction of diverse mammalian prion strains.
  Proceedings of the National Academy of Sciences of the United States of America 2009 Colby DW, Giles K, Legname G, Wille H, Baskakov IV, DeArmond SJ, Prusiner SB
• Natural and synthetic prion structure from X-ray fiber diffraction.
  Proceedings of the National Academy of Sciences of the United States of America 2009 Wille H, Bian W, McDonald M, Kendall A, Colby DW, Bloch L, Ollesch J, Borovinskiy AL, Cohen FE, Prusiner SB, Stubbs G
• Asymptomatic deer excrete infectious prions in faeces.
  Nature 2009 Tamgüney G, Miller MW, Wolfe LL, Sirochman TM, Glidden DV, Palmer C, Lemus A, DeArmond SJ, Prusiner SB
• Prion proteins with pathogenic and protective mutations show similar structure and dynamics.
  Biochemistry 2009 Bae SH, Legname G, Serban A, Prusiner SB, Wright PE, Dyson HJ
• Measuring prions by bioluminescence imaging.
  Proceedings of the National Academy of Sciences of the United States of America 2009 Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB
• Is Parkinson's disease a prion disorder?
  Proceedings of the National Academy of Sciences of the United States of America 2009 Olanow CW, Prusiner SB
• Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease.
  Laboratory investigation; a journal of technical methods and pathology 2009 Choi EM, Geschwind MD, Deering C, Pomeroy K, Kuo A, Miller BL, Safar JG, Prusiner SB
• Development of antibody fragments for immunotherapy of prion diseases.
  The Biochemical journal 2009 Campana V, Zentilin L, Mirabile I, Kranjc A, Casanova P, Giacca M, Prusiner SB, Legname G, Zurzolo C
• Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein.
  The Journal of general virology 2009 Tamgüney G, Miller MW, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB
• Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 2009 Wille H, Shanmugam M, Murugesu M, Ollesch J, Stubbs G, Long JR, Safar JG, Prusiner SB
• Cryo-immunogold electron microscopy for prions: toward identification of a conversion site.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Godsave SF, Wille H, Kujala P, Latawiec D, DeArmond SJ, Serban A, Prusiner SB, Peters PJ
• Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation.
  PLoS pathogens 2008 Giles K, Glidden DV, Beckwith R, Seoanes R, Peretz D, DeArmond SJ, Prusiner SB
• A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.
  Proceedings of the National Academy of Sciences of the United States of America 2008 Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ
• Genes contributing to prion pathogenesis.
  The Journal of general virology 2008 Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz…
• Transmission and detection of prions in feces.
  The Journal of infectious diseases 2008 Safar JG, Lessard P, Tamgüney G, Freyman Y, Deering C, Letessier F, Dearmond SJ, Prusiner SB
• Mechanisms of prion protein assembly into amyloid.
  Proceedings of the National Academy of Sciences of the United States of America 2008 Stöhr J, Weinmann N, Wille H, Kaimann T, Nagel-Steger L, Birkmann E, Panza G, Prusiner SB, Eigen M, Riesner D
• Small-molecule aggregates inhibit amyloid polymerization.
  Nature chemical biology 2008 Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK
• Prion detection by an amyloid seeding assay.
  Proceedings of the National Academy of Sciences of the United States of America 2007 Colby DW, Zhang Q, Wang S, Groth D, Legname G, Riesner D, Prusiner SB
• Cell division modulates prion accumulation in cultured cells.
  Proceedings of the National Academy of Sciences of the United States of America 2007 Ghaemmaghami S, Phuan PW, Perkins B, Ullman J, May BC, Cohen FE, Prusiner SB
• Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation.
  The Journal of biological chemistry 2007 Müller H, Stitz L, Wille H, Prusiner SB, Riesner D
• Electron crystallography of the scrapie prion protein complexed with heavy metals.
  Archives of biochemistry and biophysics 2007 Wille H, Govaerts C, Borovinskiy A, Latawiec D, Downing KH, Cohen FE, Prusiner SB
• Polio and Nobel prizes: looking back 50 years.
  Annals of neurology 2007 Norrby E, Prusiner SB
• Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds.
  The Journal of general virology 2007 Phuan PW, Zorn JA, Safar J, Giles K, Prusiner SB, Cohen FE, May BCH
• Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells.
  Molecular medicine (Cambridge, Mass.) 2007 Karpuj MV, Giles K, Gelibter-Niv S, Scott MR, Lingappa VR, Szoka FC, Peretz D, Denetclaw W, Prusiner SB
• Transgenic mouse brains for the evaluation and quality control of BSE tests.
  Biological chemistry 2007 Philipp WJ, Groth D, Giles K, Vodrazka P, Schimmel H, Feyssaguet M, Toomik R, Schacher P, Osman AA, Lachmann I, Wear A, Arsac JN, Prusiner SB
• Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites.
  Journal of molecular biology 2007 King DJ, Safar JG, Legname G, Prusiner SB
• Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.
  Journal of medicinal chemistry 2007 May BC, Zorn JA, Witkop J, Sherrill J, Wallace AC, Legname G, Prusiner SB, Cohen FE
• Developmental expression of PrP in the post-implantation embryo.
  Brain research 2006 Tremblay P, Bouzamondo-Bernstein E, Heinrich C, Prusiner SB, DeArmond SJ
• Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Legname G, Nguyen HO, Peretz D, Cohen FE, DeArmond SJ, Prusiner SB
• Transmission of elk and deer prions to transgenic mice.
  Journal of virology 2006 Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB
• Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.
  NeuroImage 2006 Boy J, Leergaard TB, Schmidt T, Odeh F, Bichelmeier U, Nuber S, Holzmann C, Wree A, Prusiner SB, Bujard H, Riess O, Bjaalie JG
• Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells.
  Bioorganic & medicinal chemistry letters 2006 May BC, Witkop J, Sherrill J, Anderson MO, Madrid PB, Zorn JA, Prusiner SB, Cohen FE, Guy RK
• Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation.
  Journal of molecular biology 2006 Luginbühl B, Kanyo Z, Jones RM, Fletterick RJ, Prusiner SB, Cohen FE, Williamson RA, Burton DR, Plückthun A
• Human prions and plasma lipoproteins.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Safar JG, Wille H, Geschwind MD, Deering C, Latawiec D, Serban A, King DJ, Legname G, Weisgraber KH, Mahley RW, Miller BL, Dearmond SJ, Prusiner SB
• Copper induces conformational changes in the N-terminal part of cell-surface PrPC.
  Archives of virology 2006 Leclerc E, Serban H, Prusiner SB, Burton DR, Williamson RA
• Changes in neuropeptide expression in mice infected with prions.
  Neurobiology of aging 2006 Diez M, Groth D, DeArmond SJ, Prusiner SB, Hökfelt T
• Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein.
  Drug metabolism and disposition: the biological fate of chemicals 2006 Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET
• Prion infection of mouse neurospheres.
  Proceedings of the National Academy of Sciences of the United States of America 2006 Giri RK, Young R, Pitstick R, DeArmond SJ, Prusiner SB, Carlson GA
• Discovering DNA encodes heredity and prions are infectious proteins.
  Annual review of genetics 2006 Prusiner SB, McCarty M
• Inactivation of prions by acidic sodium dodecyl sulfate.
  Journal of virology 2006 Peretz D, Supattapone S, Giles K, Vergara J, Freyman Y, Lessard P, Safar JG, Glidden DV, McCulloch C, Nguyen HO, Scott M, Dearmond SJ, Prusiner SB
• Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro.
  Journal of neurochemistry 2005 Kanaani J, Prusiner SB, Diacovo J, Baekkeskov S, Legname G
• Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L).
  Solid state nuclear magnetic resonance 2005 Lim KH, Nguyen TN, Damo SM, Mazur T, Ball HL, Prusiner SB, Pines A, Wemmer DE
• Selective precipitation of prions by polyoxometalate complexes.
  Journal of the American Chemical Society 2005 Lee IS, Long JR, Prusiner SB, Safar JG
• Prion clearance in bigenic mice.
  The Journal of general virology 2005 Safar JG, DeArmond SJ, Kociuba K, Deering C, Didorenko S, Bouzamondo-Bernstein E, Prusiner SB, Tremblay P
• Search for a prion-specific nucleic acid.
  Journal of virology 2005 Safar JG, Kellings K, Serban A, Groth D, Cleaver JE, Prusiner SB, Riesner D
• Assembly of natural and recombinant prion protein into fibrils.
  Biological chemistry 2005 Leffers KW, Wille H, Stöhr J, Junger E, Prusiner SB, Riesner D
• Transmission barriers for bovine, ovine, and human prions in transgenic mice.
  Journal of virology 2005 Scott MR, Peretz D, Nguyen HO, Dearmond SJ, Prusiner SB
• Diagnosis of human prion disease.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Safar JG, Geschwind MD, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, Dearmond SJ, Prusiner SB
• Strain-specified characteristics of mouse synthetic prions.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Legname G, Nguyen HO, Baskakov IV, Cohen FE, Dearmond SJ, Prusiner SB
• Notch-1 activation and dendritic atrophy in prion disease.
  Proceedings of the National Academy of Sciences of the United States of America 2005 Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ
• Oxidation of methionine residues in the prion protein by hydrogen peroxide.
  Archives of biochemistry and biophysics 2004 Requena JR, Dimitrova MN, Legname G, Teijeira S, Prusiner SB, Levine RL
• Pharmacokinetics of quinacrine in the treatment of prion disease.
  BMC infectious diseases 2004 Yung L, Huang Y, Lessard P, Legname G, Lin ET, Baldwin M, Prusiner SB, Ryou C, Guglielmo BJ
• Immunoglobulins in urine of hamsters with scrapie.
  The Journal of biological chemistry 2004 Serban A, Legname G, Hansen K, Kovaleva N, Prusiner SB
• The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system.
  Journal of neuropathology and experimental neurology 2004 Bouzamondo-Bernstein E, Hopkins SD, Spilman P, Uyehara-Lock J, Deering C, Safar J, Prusiner SB, Ralston HJ, DeArmond SJ
• Synthetic mammalian prions.
  Science (New York, N.Y.) 2004 Legname G, Baskakov IV, Nguyen HO, Riesner D, Cohen FE, DeArmond SJ, Prusiner SB
• Detecting mad cow disease.
  Scientific American 2004 Prusiner SB
• Evidence for assembly of prions with left-handed beta-helices into trimers.
  Proceedings of the National Academy of Sciences of the United States of America 2004 Govaerts C, Wille H, Prusiner SB, Cohen FE
• Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.
  Nature biotechnology 2004 Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA
• Prions: so many fibers, so little infectivity.
  Trends in biochemical sciences 2004 May BC, Govaerts C, Prusiner SB, Cohen FE
• The peculiar nature of unfolding of the human prion protein.
  Protein science : a publication of the Protein Society 2004 Baskakov IV, Legname G, Gryczynski Z, Prusiner SB
• Mutant PrPSc conformers induced by a synthetic peptide and several prion strains.
  Journal of virology 2004 Tremblay P, Ball HL, Kaneko K, Groth D, Hegde RS, Cohen FE, DeArmond SJ, Prusiner SB, Safar JG
• When sporadic disease is not sporadic: the potential for genetic etiology.
  Archives of neurology 2004 Goldman JS, Miller BL, Safar J, de Tourreil S, Martindale JL, Prusiner SB, Geschwind MD
• Early evidence that a protease-resistant protein is an active component of the infectious prion.
  Cell 2004 Prusiner SB
• Trafficking of prion proteins through a caveolae-mediated endosomal pathway.
  The Journal of cell biology 2003 Peters PJ, Mironov A, Peretz D, van Donselaar E, Leclerc E, Erpel S, DeArmond SJ, Burton DR, Williamson RA, Vey M, Prusiner SB
• Cytosolic prion protein in neurons.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Mironov A, Latawiec D, Wille H, Bouzamondo-Bernstein E, Legname G, Williamson RA, Burton D, DeArmond SJ, Prusiner SB, Peters PJ
• Copper coordination in the full-length, recombinant prion protein.
  Biochemistry 2003 Burns CS, Aronoff-Spencer E, Legname G, Prusiner SB, Antholine WE, Gerfen GJ, Peisach J, Millhauser GL
• Differential inhibition of prion propagation by enantiomers of quinacrine.
  Laboratory investigation; a journal of technical methods and pathology 2003 Ryou C, Legname G, Peretz D, Craig JC, Baldwin MA, Prusiner SB
• Cooperative binding of dominant-negative prion protein to kringle domains.
  Journal of molecular biology 2003 Ryou C, Prusiner SB, Legname G
• Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene.
  Proceedings of the National Academy of Sciences of the United States of America 2003 Korth C, Kaneko K, Groth D, Heye N, Telling G, Mastrianni J, Parchi P, Gambetti P, Will R, Ironside J, Heinrich C, Tremblay P, DeArmond SJ, Prusiner SB
• Potent inhibition of scrapie prion replication in cultured cells by bis-acridines.
  Proceedings of the National Academy of Sciences of the United States of America 2003 May BC, Fafarman AT, Hong SB, Rogers M, Deady LW, Prusiner SB, Cohen FE
• Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment.
  Clinics in laboratory medicine 2003 DeArmond SJ, Prusiner SB
• Conformation of PrP(C) on the cell surface as probed by antibodies.
  Journal of molecular biology 2003 Leclerc E, Peretz D, Ball H, Solforosi L, Legname G, Safar J, Serban A, Prusiner SB, Burton DR, Williamson RA
• The PrP-like protein Doppel binds copper.
  The Journal of biological chemistry 2002 Qin K, Coomaraswamy J, Mastrangelo P, Yang Y, Lugowski S, Petromilli C, Prusiner SB, Fraser PE, Goldberg JM, Chakrabartty A, Westaway D
• Historical essay. Discovering the cause of AIDS.
  Science (New York, N.Y.) 2002 Prusiner SB
• Prion and doppel proteins bind to granule cells of the cerebellum.
  Proceedings of the National Academy of Sciences of the United States of America 2002 Legname G, Nelken P, Guan Z, Kanyo ZF, DeArmond SJ, Prusiner SB
• Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice.
  Nature biotechnology 2002 Safar JG, Scott M, Monaghan J, Deering C, Didorenko S, Vergara J, Ball H, Legname G, Leclerc E, Solforosi L, Serban H, Groth D, Burton DR, Prusiner SB, Williamson RA
• Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?
  Biochemistry 2002 Kuwata K, Li H, Yamada H, Legname G, Prusiner SB, Akasaka K, James TL
• Dominant-negative inhibition of prion replication in transgenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 2002 Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, DeArmond SJ, Cohen FE, Prusiner SB, Wallace AC
• A change in the conformation of prions accompanies the emergence of a new prion strain.
  Neuron 2002 Peretz D, Williamson RA, Legname G, Matsunaga Y, Vergara J, Burton DR, DeArmond SJ, Prusiner SB, Scott MR
• Pathway complexity of prion protein assembly into amyloid.
  The Journal of biological chemistry 2002 Baskakov IV, Legname G, Baldwin MA, Prusiner SB, Cohen FE
• Prions in skeletal muscle.
  Proceedings of the National Academy of Sciences of the United States of America 2002 Bosque PJ, Ryou C, Telling G, Peretz D, Legname G, DeArmond SJ, Prusiner SB
• Structural studies of the scrapie prion protein by electron crystallography.
  Proceedings of the National Academy of Sciences of the United States of America 2002 Wille H, Michelitsch MD, Guenebaut V, Supattapone S, Serban A, Cohen FE, Agard DA, Prusiner SB
• Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation.
  Journal of molecular biology 2002 Nicholson EM, Mo H, Prusiner SB, Cohen FE, Marqusee S
• Inherited prion disease caused by the V210I mutation: transmission to transgenic mice.
  Neurology 2001 Mastrianni JA, Capellari S, Telling GC, Han D, Bosque P, Prusiner SB, DeArmond SJ
• Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein.
  Journal of molecular biology 2001 Schmitt-Ulms G, Legname G, Baldwin MA, Ball HL, Bradon N, Bosque PJ, Crossin KL, Edelman GM, DeArmond SJ, Cohen FE, Prusiner SB
• Doppel-induced cerebellar degeneration in transgenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P
• Engineering the prion protein using chemical synthesis.
  The journal of peptide research : official journal of the American Peptide Society 2001 Ball HL, King DS, Cohen FE, Prusiner SB, Baldwin MA
• Huntington disease phenocopy is a familial prion disease.
  American journal of human genetics 2001 Moore RC, Xiang F, Monaghan J, Han D, Zhang Z, Edström L, Anvret M, Prusiner SB
• Induction of distinct [URE3] yeast prion strains.
  Molecular and cellular biology 2001 Schlumpberger M, Prusiner SB, Herskowitz I
• Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Laws DD, Bitter HM, Liu K, Ball HL, Kaneko K, Wille H, Cohen FE, Prusiner SB, Pines A, Wemmer DE
• Antibodies inhibit prion propagation and clear cell cultures of prion infectivity.
  Nature 2001 Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB
• Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Korth C, May BC, Cohen FE, Prusiner SB
• Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH.
  Proteins 2001 Matsunaga Y, Peretz D, Williamson A, Burton D, Mehlhorn I, Groth D, Cohen FE, Prusiner SB, Baldwin MA
• Decreased MK-801 binding in discrete hippocampal regions of prion-infected mice.
  Neurobiology of disease 2001 Diez M, DeArmond SJ, Groth D, Prusiner SB, Hökfelt T
• Copper-catalyzed oxidation of the recombinant SHa(29-231) prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Requena JR, Groth D, Legname G, Stadtman ER, Prusiner SB, Levine RL
• Shattuck lecture--neurodegenerative diseases and prions.
  The New England journal of medicine 2001 Prusiner SB
• Folding of prion protein to its native alpha-helical conformation is under kinetic control.
  The Journal of biological chemistry 2001 Baskakov IV, Legname G, Prusiner SB, Cohen FE
• Prion glycoprotein: structure, dynamics, and roles for the sugars.
  Biochemistry 2001 Rudd PM, Wormald MR, Wing DR, Prusiner SB, Dwek RA
• Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form.
  The EMBO journal 2001 Leclerc E, Peretz D, Ball H, Sakurai H, Legname G, Serban A, Prusiner SB, Burton DR, Williamson RA
• A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice.
  Molecular and cellular biology 2001 Supattapone S, Bouzamondo E, Ball HL, Wille H, Nguyen HO, Cohen FE, DeArmond SJ, Prusiner SB, Scott M
• Branched polyamines cure prion-infected neuroblastoma cells.
  Journal of virology 2001 Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka FC, Cohen FE, Prusiner SB, Scott MR
• Conformational propagation with prion-like characteristics in a simple model of protein folding.
  Protein science : a publication of the Protein Society 2001 Harrison PM, Chan HS, Prusiner SB, Cohen FE
• Strain-specified relative conformational stability of the scrapie prion protein.
  Protein science : a publication of the Protein Society 2001 Peretz D, Scott MR, Groth D, Williamson RA, Burton DR, Cohen FE, Prusiner SB
• Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form.
  Biological chemistry 2001 Jansen K, Schäfer O, Birkmann E, Post K, Serban H, Prusiner SB, Riesner D
• Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics.
  Biochemistry 2001 Viles JH, Donne D, Kroon G, Prusiner SB, Cohen FE, Dyson HJ, Wright PE
• Two different neurodegenerative diseases caused by proteins with similar structures.
  Proceedings of the National Academy of Sciences of the United States of America 2001 Mo H, Moore RC, Cohen FE, Westaway D, Prusiner SB, Wright PE, Dyson HJ
• Identification of two prion protein regions that modify scrapie incubation time.
  Journal of virology 2001 Supattapone S, Muramoto T, Legname G, Mehlhorn I, Cohen FE, DeArmond SJ, Prusiner SB, Scott MR
• Affinity-tagged miniprion derivatives spontaneously adopt protease-resistant conformations.
  Journal of virology 2000 Supattapone S, Nguyen HO, Muramoto T, Cohen FE, DeArmond SJ, Prusiner SB, Scott M
• Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy.
  Biochemistry 2000 Aronoff-Spencer E, Burns CS, Avdievich NI, Gerfen GJ, Peisach J, Antholine WE, Ball HL, Cohen FE, Prusiner SB, Millhauser GL
• Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains.
  The Journal of general virology 2000 Korth C, Kaneko K, Prusiner SB
• Quantitative trait loci affecting prion incubation time in mice.
  Genomics 2000 Stephenson DA, Chiotti K, Ebeling C, Groth D, DeArmond SJ, Prusiner SB, Carlson GA
• Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.
  The Journal of biological chemistry 2000 Silverman GL, Qin K, Moore RC, Yang Y, Mastrangelo P, Tremblay P, Prusiner SB, Cohen FE, Westaway D
• Selective neuronal vulnerability during experimental scrapie infection: insights from an ultrastructural investigation.
  Brain research 2000 Bouzamondo E, Milroy AM, Ralston HJ, Prusiner SB, DeArmond SJ
• Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions.
  Journal of molecular biology 2000 Inouye H, Bond J, Baldwin MA, Ball HL, Prusiner SB, Kirschner DA
• Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein.
  Journal of structural biology 2000 Wille H, Prusiner SB, Cohen FE
• Mimicking dominant negative inhibition of prion replication through structure-based drug design.
  Proceedings of the National Academy of Sciences of the United States of America 2000 Perrier V, Wallace AC, Kaneko K, Safar J, Prusiner SB, Cohen FE
• Cultured cell sublines highly susceptible to prion infection.
  Journal of virology 2000 Bosque PJ, Prusiner SB
• Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein.
  Journal of virology 2000 Zulianello L, Kaneko K, Scott M, Erpel S, Han D, Cohen FE, Prusiner SB
• Self-assembly of recombinant prion protein of 106 residues.
  Biochemistry 2000 Baskakov IV, Aagaard C, Mehlhorn I, Wille H, Groth D, Baldwin MA, Prusiner SB, Cohen FE
• The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein.
  Protein science : a publication of the Protein Society 2000 Schlumpberger M, Wille H, Baldwin MA, Butler DA, Herskowitz I, Prusiner SB
• Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry.
  Protein science : a publication of the Protein Society 2000 Whittal RM, Ball HL, Cohen FE, Burlingame AL, Prusiner SB, Baldwin MA
• A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice.
  Journal of molecular biology 2000 Kaneko K, Ball HL, Wille H, Zhang H, Groth D, Torchia M, Tremblay P, Safar J, Prusiner SB, DeArmond SJ, Baldwin MA, Cohen FE
• Quantitative traits of prion strains are enciphered in the conformation of the prion protein.
  Archives of virology. Supplementum 2000 Safar J, Cohen FE, Prusiner SB
• Transgenic models of prion disease.
  Archives of virology. Supplementum 2000 Scott MR, Supattapone S, Nguyen HO, DeArmond SJ, Prusiner SB
• Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans.
  Proceedings of the National Academy of Sciences of the United States of America 1999 Scott MR, Will R, Ironside J, Nguyen HO, Tremblay P, DeArmond SJ, Prusiner SB
• Transmissible and genetic prion diseases share a common pathway of neurodegeneration.
  Nature 1999 Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB, Lingappa VR
• Elimination of prions by branched polyamines and implications for therapeutics.
  Proceedings of the National Academy of Sciences of the United States of America 1999 Supattapone S, Nguyen HO, Cohen FE, Prusiner SB, Scott MR
• Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie.
  Journal of neuropathology and experimental neurology 1999 Tatzelt J, Groth DF, Torchia M, Prusiner SB, DeArmond SJ
• Glycosylation differences between the normal and pathogenic prion protein isoforms.
  Proceedings of the National Academy of Sciences of the United States of America 1999 Rudd PM, Endo T, Colominas C, Groth D, Wheeler SF, Harvey DJ, Wormald MR, Serban H, Prusiner SB, Kobata A, Dwek RA
• Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.
  Journal of molecular biology 1999 Kanyo ZF, Pan KM, Williamson RA, Burton DR, Prusiner SB, Fletterick RJ, Cohen FE
• Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.
  Journal of molecular biology 1999 Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, Cohen FE, Prusiner SB, …
• A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.
  Laboratory investigation; a journal of technical methods and pathology 1999 Nishida N, Tremblay P, Sugimoto T, Shigematsu K, Shirabe S, Petromilli C, Erpel SP, Nakaoke R, Atarashi R, Houtani T, Torchia M, Sakaguchi S, DeArmond SJ, Prusiner SB, Katamine S
• Prion protein conformation in a patient with sporadic fatal insomnia.
  The New England journal of medicine 1999 Mastrianni JA, Nixon R, Layzer R, Telling GC, Han D, DeArmond SJ, Prusiner SB
• Solution structure of Syrian hamster prion protein rPrP(90-231).
  Biochemistry 1999 Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL
• Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice.
  Cell 1999 Supattapone S, Bosque P, Muramoto T, Wille H, Aagaard C, Peretz D, Nguyen HO, Heinrich C, Torchia M, Safar J, Cohen FE, DeArmond SJ, Prusiner SB, Scott M
• Copper binding to the prion protein: structural implications of four identical cooperative binding sites.
  Proceedings of the National Academy of Sciences of the United States of America 1999 Viles JH, Cohen FE, Prusiner SB, Goodin DB, Wright PE, Dyson HJ
• Thermodynamics of model prions and its implications for the problem of prion protein folding.
  Journal of molecular biology 1999 Harrison PM, Chan HS, Prusiner SB, Cohen FE
• Ultrastructural studies on scrapie prion protein crystals obtained from reverse micellar solutions.
  Biophysical journal 1999 Wille H, Prusiner SB
• Prions.
  Proceedings of the National Academy of Sciences of the United States of America 1998 Prusiner SB
• Mapping the prion protein using recombinant antibodies.
  Journal of virology 1998 Williamson RA, Peretz D, Pinilla C, Ball H, Bastidas RB, Rozenshteyn R, Houghten RA, Prusiner SB, Burton DR
• Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation.
  Biological chemistry 1998 Post K, Pitschke M, Schäfer O, Wille H, Appel TR, Kirsch D, Mehlhorn I, Serban H, Prusiner SB, Riesner D
• Doxycycline control of prion protein transgene expression modulates prion disease in mice.
  Proceedings of the National Academy of Sciences of the United States of America 1998 Tremblay P, Meiner Z, Galou M, Heinrich C, Petromilli C, Lisse T, Cayetano J, Torchia M, Mobley W, Bujard H, DeArmond SJ, Prusiner SB
• Complete genomic sequence and analysis of the prion protein gene region from three mammalian species.
  Genome research 1998 Lee IY, Westaway D, Smit AF, Wang K, Seto J, Chen L, Acharya C, Ankener M, Baskin D, Cooper C, Yao H, Prusiner SB, Hood LE
• Eight prion strains have PrP(Sc) molecules with different conformations.
  Nature medicine 1998 Safar J, Wille H, Itri V, Groth D, Serban H, Torchia M, Cohen FE, Prusiner SB
• The three-dimensional structure of prion protein: implications for prion disease.
  Biochemical Society transactions 1998 Baldwin MA, James TL, Cohen FE, Prusiner SB
• The prion diseases.
  Brain pathology (Zurich, Switzerland) 1998 Prusiner SB
• Prion protein selectively binds copper(II) ions.
  Biochemistry 1998 Stöckel J, Safar J, Wallace AC, Cohen FE, Prusiner SB
• Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system.
  Brain research. Brain research reviews 1998 Hökfelt T, Broberger C, Zhang X, Diez M, Kopp J, Xu Z, Landry M, Bao L, Schalling M, Koistinaho J, DeArmond SJ, Prusiner S, Gong J, Walsh JH
• Prion protein biology.
  Cell 1998 Prusiner SB, Scott MR, DeArmond SJ, Cohen FE
• A transmembrane form of the prion protein in neurodegenerative disease.
  Science (New York, N.Y.) 1998 Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR
• Changes in the localization of brain prion proteins during scrapie infection.
  Neurology 1998 DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB
• Molecular studies of prion diseases.
  Progress in brain research 1998 Safar J, Prusiner SB
• Pathologic conformations of prion proteins.
  Annual review of biochemistry 1998 Cohen FE, Prusiner SB
• Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Scott MR, Safar J, Telling G, Nguyen O, Groth D, Torchia M, Koehler R, Tremblay P, Walther D, Cohen FE, DeArmond SJ, Prusiner SB
• Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Donne DG, Viles JH, Groth D, Mehlhorn I, James TL, Cohen FE, Prusiner SB, Wright PE, Dyson HJ
• Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system.
  Protein engineering 1997 Blochberger TC, Cooper C, Peretz D, Tatzelt J, Griffith OH, Baldwin MA, Prusiner SB
• Propagation of prion strains through specific conformers of the prion protein.
  Journal of virology 1997 Scott MR, Groth D, Tatzelt J, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB
• Selective neuronal targeting in prion disease.
  Neuron 1997 DeArmond SJ, Sánchez H, Yehiely F, Qiu Y, Ninchak-Casey A, Daggett V, Camerino AP, Cayetano J, Rogers M, Groth D, Torchia M, Tremblay P, Scott MR, Cohen FE, Prusiner SB
• Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Diez M, Koistinaho J, Dearmond SJ, Groth D, Prusiner SB, Hökfelt T
• A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.
  Journal of virology 1997 Schätzl HM, Laszlo L, Holtzman DM, Tatzelt J, DeArmond SJ, Weiner RI, Mobley WC, Prusiner SB
• A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform.
  Journal of molecular biology 1997 Peretz D, Williamson RA, Matsunaga Y, Serban H, Pinilla C, Bastidas RB, Rozenshteyn R, James TL, Houghten RA, Cohen FE, Prusiner SB, Burton DR
• Prion diseases and the BSE crisis.
  Science (New York, N.Y.) 1997 Prusiner SB
• Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Kaneko K, Zulianello L, Scott M, Cooper CM, Wallace AC, James TL, Cohen FE, Prusiner SB
• Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform.
  Proceedings of the National Academy of Sciences of the United States of America 1997 James TL, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE
• Molecular properties of complexes formed between the prion protein and synthetic peptides.
  Journal of molecular biology 1997 Kaneko K, Wille H, Mehlhorn I, Zhang H, Ball H, Cohen FE, Baldwin MA, Prusiner SB
• Familial Creutzfeldt-Jakob disease. Codon 200 prion disease in Libyan Jews.
  Medicine 1997 Meiner Z, Gabizon R, Prusiner SB
• Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix.
  Nature medicine 1997 Muramoto T, DeArmond SJ, Scott M, Telling GC, Cohen FE, Prusiner SB
• Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR.
  Chemistry & biology 1997 Lundberg KM, Stenland CJ, Cohen FE, Prusiner SB, Millhauser GL
• N-terminally tagged prion protein supports prion propagation in transgenic mice.
  Protein science : a publication of the Protein Society 1997 Telling GC, Tremblay P, Torchia M, Dearmond SJ, Cohen FE, Prusiner SB
• Physical studies of conformational plasticity in a recombinant prion protein.
  Biochemistry 1997 Zhang H, Stockel J, Mehlhorn I, Groth D, Baldwin MA, Prusiner SB, James TL, Cohen FE
• COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform.
  Proceedings of the National Academy of Sciences of the United States of America 1997 Kaneko K, Vey M, Scott M, Pilkuhn S, Cohen FE, Prusiner SB
• Failure to transmit disease from gray tremor mutant mice.
  Journal of virology 1997 Carlson GA, Banks S, Lund D, Reichert C, Groth D, Torchia M, Dearmond SJ, Prusiner SB
• The prion folding problem.
  Current opinion in structural biology 1997 Harrison PM, Bamborough P, Daggett V, Prusiner SB, Cohen FE
• Prion protein gene variation among primates.
  Journal of molecular biology 1997 Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB
• Genetics of prions.
  Annual review of genetics 1997 Prusiner SB, Scott MR
• Identification of candidate proteins binding to prion protein.
  Neurobiology of disease 1997 Yehiely F, Bamborough P, Da Costa M, Perry BJ, Thinakaran G, Cohen FE, Carlson GA, Prusiner SB
• Recombinant scrapie-like prion protein of 106 amino acids is soluble.
  Proceedings of the National Academy of Sciences of the United States of America 1996 Muramoto T, Scott M, Cohen FE, Prusiner SB
• Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity.
  Science (New York, N.Y.) 1996 Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, Gabizon R, Mastrianni J, Lugaresi E, Gambetti P, Prusiner SB
• Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains.
  Proceedings of the National Academy of Sciences of the United States of America 1996 Vey M, Pilkuhn S, Wille H, Nixon R, DeArmond SJ, Smart EJ, Anderson RG, Taraboulos A, Prusiner SB
• Chemical chaperones interfere with the formation of scrapie prion protein.
  The EMBO journal 1996 Tatzelt J, Prusiner SB, Welch WJ
• Molecular biology and pathogenesis of prion diseases.
  Trends in biochemical sciences 1996 Prusiner SB
• Mutation of the prion protein gene at codon 208 in familial Creutzfeldt-Jakob disease.
  Neurology 1996 Mastrianni JA, Iannicola C, Myers RM, DeArmond S, Prusiner SB
• Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release.
  Neurology 1996 Wong K, Qiu Y, Hyun W, Nixon R, VanCleff J, Sanchez-Salazar J, Prusiner SB, DeArmond SJ
• Prion biology and diseases--laughing cannibals, mad cows, and scientific heresy.
  Medicinal research reviews 1996 Prusiner SB
• Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice.
  Neuroreport 1996 Diez M, Koistinaho J, DeArmond SJ, Camerino AP, Groth D, Caytano JC, Prusiner SB, Hökfelt T
• Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein.
  Neurology 1996 Tatzelt J, Maeda N, Pekny M, Yang SL, Betsholtz C, Eliasson C, Cayetano J, Camerino AP, DeArmond SJ, Prusiner SB
• Solid-state NMR studies of the prion protein H1 fragment.
  Protein science : a publication of the Protein Society 1996 Heller J, Kolbert AC, Larsen R, Ernst M, Bekker T, Baldwin M, Prusiner SB, Pines A, Wemmer DE
• Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice.
  Genes & development 1996 Telling GC, Haga T, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB
• Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 1996 Williamson RA, Peretz D, Smorodinsky N, Bastidas R, Serban H, Mehlhorn I, DeArmond SJ, Prusiner SB, Burton DR
• Separation of scrapie prion infectivity from PrP amyloid polymers.
  Journal of molecular biology 1996 Wille H, Zhang GF, Baldwin MA, Cohen FE, Prusiner SB
• High-level expression and characterization of a purified 142-residue polypeptide of the prion protein.
  Biochemistry 1996 Mehlhorn I, Groth D, Stöckel J, Moffat B, Reilly D, Yansura D, Willett WS, Baldwin M, Fletterick R, Cohen FE, Vandlen R, Henner D, Prusiner SB
• Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
  Proceedings of the National Academy of Sciences of the United States of America 1996 Lledo PM, Tremblay P, DeArmond SJ, Prusiner SB, Nicoll RA
• Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.
  Journal of virology 1996 Riesner D, Kellings K, Post K, Wille H, Serban H, Groth D, Baldwin MA, Prusiner SB
• Abnormal plasma membrane properties and functions in prion-infected cell lines.
  Cold Spring Harbor symposia on quantitative biology 1996 DeArmond SJ, Qiu Y, Wong K, Nixon R, Hyun W, Prusiner SB, Mobley WC
• Human prion diseases and neurodegeneration.
  Current topics in microbiology and immunology 1996 Prusiner SB
• Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease.
  Nature medicine 1996 Gabizon R, Telling G, Meiner Z, Halimi M, Kahana I, Prusiner SB
• Lipid composition in scrapie-infected mouse brain: prion infection increases the levels of dolichyl phosphate and ubiquinone.
  Journal of neurochemistry 1996 Guan Z, Söderberg M, Sindelar P, Prusiner SB, Kristensson K, Dallner G
• Molecular biology and genetics of prion diseases.
  Cold Spring Harbor symposia on quantitative biology 1996 Prusiner SB
• Prion protein amyloid: separation of scrapie infectivity from PrP polymers.
  Ciba Foundation symposium 1996 Wille H, Baldwin MA, Cohen FE, DeArmond SJ, Prusiner SB
• Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations.
  Cold Spring Harbor symposia on quantitative biology 1996 Bamborough P, Wille H, Telling GC, Yehiely F, Prusiner SB, Cohen FE
• Scrapie prions: a three-dimensional model of an infectious fragment.
  Folding & design 1996 Huang Z, Prusiner SB, Cohen FE
• Structures of prion proteins and conformational models for prion diseases.
  Current topics in microbiology and immunology 1996 Huang Z, Prusiner SB, Cohen FE
• Transgenetics and gene targeting in studies of prion diseases.
  Current topics in microbiology and immunology 1996 Scott MR, Telling GC, Prusiner SB
• Transgenetics and neuropathology of prion diseases.
  Current topics in microbiology and immunology 1996 DeArmond SJ, Prusiner SB
• Transgenetics of prion diseases.
  Current topics in microbiology and immunology 1996 Prusiner SB
• Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
  Proceedings of the National Academy of Sciences of the United States of America 1995 Kaneko K, Peretz D, Pan KM, Blochberger TC, Wille H, Gabizon R, Griffith OH, Cohen FE, Baldwin MA, Prusiner SB
• Prion disease (PrP-A117V) presenting with ataxia instead of dementia.
  Neurology 1995 Mastrianni JA, Curtis MT, Oberholtzer JC, Da Costa MM, DeArmond S, Prusiner SB, Garbern JY
• Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein.
  Cell 1995 Telling GC, Scott M, Mastrianni J, Gabizon R, Torchia M, Cohen FE, DeArmond SJ, Prusiner SB
• Scanning for mutations in the human prion protein open reading frame by temporal temperature gradient gel electrophoresis.
  Electrophoresis 1995 Wiese U, Wulfert M, Prusiner SB, Riesner D
• X-ray diffraction of scrapie prion rods and PrP peptides.
  Journal of molecular biology 1995 Nguyen JT, Inouye H, Baldwin MA, Fletterick RJ, Cohen FE, Prusiner SB, Kirschner DA
• Complete penetrance of Creutzfeldt-Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein gene.
  Molecular medicine (Cambridge, Mass.) 1995 Spudich S, Mastrianni JA, Wrensch M, Gabizon R, Meiner Z, Kahana I, Rosenmann H, Kahana E, Prusiner SB
• Prion protein isoforms, a convergence of biological and structural investigations.
  The Journal of biological chemistry 1995 Baldwin MA, Cohen FE, Prusiner SB
• Conformational transitions in peptides containing two putative alpha-helices of the prion protein.
  Journal of molecular biology 1995 Zhang H, Kaneko K, Nguyen JT, Livshits TL, Baldwin MA, Cohen FE, James TL, Prusiner SB
• Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster.
  Mechanisms of development 1995 Raeber AJ, Muramoto T, Kornberg TB, Prusiner SB
• Molecular genetics and biophysics of prions.
  Uirusu 1995 Prusiner SB
• Theoretical studies of sequence effects on the conformational properties of a fragment of the prion protein: implications for scrapie formation.
  Chemistry & biology 1995 Kazmirski SL, Alonso DO, Cohen FE, Prusiner SB, Daggett V
• Prion protein peptides induce alpha-helix to beta-sheet conformational transitions.
  Biochemistry 1995 Nguyen J, Baldwin MA, Cohen FE, Prusiner SB
• Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform.
  The Journal of cell biology 1995 Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, Prusiner SB, Avraham D
• Etiology and pathogenesis of prion diseases.
  The American journal of pathology 1995 DeArmond SJ, Prusiner SB
• On safari with PrP: prion diseases of animals.
  Trends in microbiology 1995 Westaway D, Carlson GA, Prusiner SB
• Scrapie prions selectively modify the stress response in neuroblastoma cells.
  Proceedings of the National Academy of Sciences of the United States of America 1995 Tatzelt J, Zuo J, Voellmy R, Scott M, Hartl U, Prusiner SB, Welch WJ
• Prion protein gene variation among primates.
  Journal of molecular biology 1995 Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB
• Prion protein transgenes and the neuropathology in prion diseases.
  Brain pathology (Zurich, Switzerland) 1995 DeArmond SJ, Prusiner SB
• The prion diseases.
  Scientific American 1995 Prusiner SB
• Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones.
  Neurobiology of disease 1994 Jefferys JG, Empson RM, Whittington MA, Prusiner SB
• Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Telling GC, Scott M, Hsiao KK, Foster D, Yang SL, Torchia M, Sidle KC, Collinge J, DeArmond SJ, Prusiner SB
• Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Hsiao KK, Groth D, Scott M, Yang SL, Serban H, Rapp D, Foster D, Torchia M, Dearmond SJ, Prusiner SB
• Neurodegeneration in humans caused by prions.
  The Western journal of medicine 1994 Prusiner SB
• Proposed three-dimensional structure for the cellular prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Huang Z, Gabriel JM, Baldwin MA, Fletterick RJ, Prusiner SB, Cohen FE
• Structure and polymorphism of the mouse prion protein gene.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Westaway D, Cooper C, Turner S, Da Costa M, Carlson GA, Prusiner SB
• Determinants of carboxyl-terminal domain translocation during prion protein biogenesis.
  The Journal of biological chemistry 1994 De Fea KA, Nakahara DH, Calayag MC, Yost CS, Mirels LF, Prusiner SB, Lingappa VR
• Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Carlson GA, Ebeling C, Yang SL, Telling G, Torchia M, Groth D, Westaway D, DeArmond SJ, Prusiner SB
• Inherited prion diseases.
  Proceedings of the National Academy of Sciences of the United States of America 1994 Prusiner SB
• Structural clues to prion replication.
  Science (New York, N.Y.) 1994 Cohen FE, Pan KM, Huang Z, Baldwin M, Fletterick RJ, Prusiner SB
• Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie.
  Genes & development 1994 Westaway D, Zuliani V, Cooper CM, Da Costa M, Neuman S, Jenny AL, Detwiler L, Prusiner SB
• Human prion diseases.
  Annals of neurology 1994 Prusiner SB, Hsiao KK
• Genetics of prion diseases and prion diversity in mice.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994 Carlson GA, DeArmond SJ, Torchia M, Westaway D, Prusiner SB
• Molecular biology and genetics of prion diseases.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994 Prusiner SB
• Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994 Gabizon R, Rosenman H, Meiner Z, Kahana I, Kahana E, Shugart Y, Ott J, Prusiner SB
• Nucleic acids in prion preparations: unspecific background or essential component?
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994 Kellings K, Prusiner SB, Riesner D
• The neuropathological phenotype in transgenic mice expressing different prion protein constructs.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1994 DeArmond SJ, Yang SL, Cayetano-Canlas J, Groth D, Prusiner SB
• Biosynthesis of the prion proteins in scrapie-infected cells in culture.
  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 1994 Taraboulos A, Scott M, Semenov A, Avrahami D, Prusiner SB
• Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in zitter rats.
  Neuroscience letters 1994 Gomi H, Ikeda T, Kunieda T, Itohara S, Prusiner SB, Yamanouchi K
• Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins.
  Cell 1994 Westaway D, DeArmond SJ, Cayetano-Canlas J, Groth D, Foster D, Yang SL, Torchia M, Carlson GA, Prusiner SB
• A national strategy for development of effective methods for the prevention and treatment of Alzheimer's disease and related neurodegenerative disorders.
  Neurobiology of aging 1994 Prusiner SB
• Biology and genetics of prion diseases.
  Annual review of microbiology 1994 Prusiner SB
• Detecting prion protein gene mutations by denaturing gradient gel electrophoresis.
  Human mutation 1994 Fink JK, Peacock ML, Warren JT, Roses AD, Prusiner SB
• Prion diseases and neurodegeneration.
  Annual review of neuroscience 1994 Prusiner SB, DeArmond SJ
• Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
  Proceedings of the National Academy of Sciences of the United States of America 1993 Prusiner SB, Groth D, Serban A, Koehler R, Foster D, Torchia M, Burton D, Yang SL, DeArmond SJ
• Genetic and infectious prion diseases.
  Archives of neurology 1993 Prusiner SB
• Scrapie prions alter receptor-mediated calcium responses in cultured cells.
  Neurology 1993 Kristensson K, Feuerstein B, Taraboulos A, Hyun WC, Prusiner SB, DeArmond SJ
• The neurochemistry of prion diseases.
  Journal of neurochemistry 1993 DeArmond SJ, Prusiner SB
• Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD).
  American journal of human genetics 1993 Gabizon R, Rosenmann H, Meiner Z, Kahana I, Kahana E, Shugart Y, Ott J, Prusiner SB
• Transgenetics and cell biology of prion diseases: investigations of PrPSc synthesis and diversity.
  British medical bulletin 1993 Prusiner SB
• Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor.
  Glycobiology 1993 Borchelt DR, Rogers M, Stahl N, Telling G, Prusiner SB
• Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform.
  Proceedings of the National Academy of Sciences of the United States of America 1993 DeArmond SJ, Yang SL, Lee A, Bowler R, Taraboulos A, Groth D, Prusiner SB
• Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.
  Cell 1993 Scott M, Groth D, Foster D, Torchia M, Yang SL, DeArmond SJ, Prusiner SB
• Biology of prion diseases.
  Journal of acquired immune deficiency syndromes 1993 Prusiner SB
• Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells.
  Proceedings of the National Academy of Sciences of the United States of America 1993 Rogers M, Yehiely F, Scott M, Prusiner SB
• Attempts to restore scrapie prion infectivity after exposure to protein denaturants.
  Proceedings of the National Academy of Sciences of the United States of America 1993 Prusiner SB, Groth D, Serban A, Stahl N, Gabizon R
• Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse.
  Genetics 1993 Carlson GA, Ebeling C, Torchia M, Westaway D, Prusiner SB
• Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.
  Biochemistry 1993 Stahl N, Baldwin MA, Teplow DB, Hood L, Gibson BW, Burlingame AL, Prusiner SB
• Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy.
  The Journal of infectious diseases 1993 Prusiner SB, Füzi M, Scott M, Serban D, Serban H, Taraboulos A, Gabriel JM, Wells GA, Wilesmith JW, Bradley R
• Transgenetic investigations of prion diseases of humans and animals.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1993 Prusiner SB
• Analysis of nucleic acids in purified scrapie prion preparations.
  Archives of virology. Supplementum 1993 Kellings K, Meyer N, Mirenda C, Prusiner SB, Riesner D
• Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity.
  Proceedings of the National Academy of Sciences of the United States of America 1993 Gasset M, Baldwin MA, Fletterick RJ, Prusiner SB
• Prion encephalopathies of animals and humans.
  Developments in biological standardization 1993 Prusiner SB
• Prions and nucleic acids: search for "residual" nucleic acids and screening for mutations in the PrP-gene.
  Developments in biological standardization 1993 Riesner D, Kellings K, Wiese U, Wulfert M, Mirenda C, Prusiner SB
• Chemistry and biology of prions.
  Biochemistry 1992 Prusiner SB
• Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.
  Proceedings of the National Academy of Sciences of the United States of America 1992 Gasset M, Baldwin MA, Lloyd DH, Gabriel JM, Holtzman DM, Cohen F, Fletterick R, Prusiner SB
• Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems.
  Journal of virology 1992 Raeber AJ, Borchelt DR, Scott M, Prusiner SB
• Molecular cloning of a candidate chicken prion protein.
  Proceedings of the National Academy of Sciences of the United States of America 1992 Gabriel JM, Oesch B, Kretzschmar H, Scott M, Prusiner SB
• Molecular cloning of a mink prion protein gene.
  The Journal of general virology 1992 Kretzschmar HA, Neumann M, Riethmüller G, Prusiner SB
• Natural and experimental prion diseases of humans and animals.
  Current opinion in neurobiology 1992 Prusiner SB
• Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred.
  Proceedings of the National Academy of Sciences of the United States of America 1992 Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F
• Purification and properties of the cellular prion protein from Syrian hamster brain.
  Protein science : a publication of the Protein Society 1992 Pan KM, Stahl N, Prusiner SB
• Evidence for synthesis of scrapie prion proteins in the endocytic pathway.
  The Journal of biological chemistry 1992 Borchelt DR, Taraboulos A, Prusiner SB
• Regional mapping of prion proteins in brain.
  Proceedings of the National Academy of Sciences of the United States of America 1992 Taraboulos A, Jendroska K, Serban D, Yang SL, DeArmond SJ, Prusiner SB
• Chimeric prion protein expression in cultured cells and transgenic mice.
  Protein science : a publication of the Protein Society 1992 Scott MR, Köhler R, Foster D, Prusiner SB
• Synthesis and trafficking of prion proteins in cultured cells.
  Molecular biology of the cell 1992 Taraboulos A, Raeber AJ, Borchelt DR, Serban D, Prusiner SB
• Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease.
  Neurology 1992 Meiner Z, Halimi M, Polakiewicz RD, Prusiner SB, Gabizon R
• Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters.
  Genes & development 1992 Hecker R, Taraboulos A, Scott M, Pan KM, Yang SL, Torchia M, Jendroska K, DeArmond SJ, Prusiner SB
• Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid.
  Biochemistry 1992 Stahl N, Baldwin MA, Hecker R, Pan KM, Burlingame AL, Prusiner SB
• Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein.
  Nature 1992 Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, Prusiner SB, Aguet M, Weissmann C
• Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis.
  The Journal of general virology 1992 Kellings K, Meyer N, Mirenda C, Prusiner SB, Riesner D
• Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene.
  Nature genetics 1992 Dlouhy SR, Hsiao K, Farlow MR, Foroud T, Conneally PM, Johnson P, Prusiner SB, Hodes ME, Ghetti B
• Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles.
  Nature genetics 1992 Hsiao K, Dlouhy SR, Farlow MR, Cass C, Da Costa M, Conneally PM, Hodes ME, Ghetti B, Prusiner SB
• Prion protein mutation at codon 102 in an Italian family with Gerstmann-Sträussler-Scheinker syndrome.
  Neurology 1992 Kretzschmar HA, Kufer P, Riethmüller G, DeArmond S, Prusiner SB, Schiffer D
• Molecular biology and genetics of neurodegenerative diseases caused by prions.
  Advances in virus research 1992 Prusiner SB
• Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells.
  Laboratory investigation; a journal of technical methods and pathology 1991 McKinley MP, Taraboulos A, Kenaga L, Serban D, Stieber A, DeArmond SJ, Prusiner SB, Gonatas N
• Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system.
  Journal of immunology (Baltimore, Md. : 1950) 1991 Rogers M, Serban D, Gyuris T, Scott M, Torchia T, Prusiner SB
• Prions and prion proteins.
  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991 Stahl N, Prusiner SB
• Electrospray mass spectrometry of the glycosylinositol phospholipid of the scrapie prion protein.
  Cell biology international reports 1991 Stahl N, Baldwin MA, Prusiner SB
• Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity.
  Neurology 1991 Jendroska K, Heinzel FP, Torchia M, Stowring L, Kretzschmar HA, Kon A, Stern A, Prusiner SB, DeArmond SJ
• Molecular biology and pathology of scrapie and the prion diseases of humans.
  Brain pathology (Zurich, Switzerland) 1991 Prusiner SB, DeArmond SJ
• Molecular biology of prion diseases.
  Science (New York, N.Y.) 1991 Prusiner SB
• A prion protein variant in a family with the telencephalic form of Gerstmann-Sträussler-Scheinker syndrome.
  Neurology 1991 Hsiao KK, Cass C, Schellenberg GD, Bird T, Devine-Gage E, Wisniewski H, Prusiner SB
• Infectious and genetic manifestations of prion diseases.
  Molecular plant-microbe interactions : MPMI 1991 Prusiner SB, Westaway D
• Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease.
  The New England journal of medicine 1991 Hsiao K, Meiner Z, Kahana E, Cass C, Kahana I, Avrahami D, Scarlato G, Abramsky O, Prusiner SB, Gabizon R
• Molecular biology and genetics of prions--implications for sheep scrapie, "mad cows" and the BSE epidemic. Historical background.
  The Cornell veterinarian 1991 Prusiner SB, Torchia M, Westaway D
• Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.
  The EMBO journal 1991 Tagliavini F, Prelli F, Ghiso J, Bugiani O, Serban D, Prusiner SB, Farlow MR, Ghetti B, Frangione B
• Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis.
  Journal of virology 1991 McKinley MP, Meyer RK, Kenaga L, Rahbar F, Cotter R, Serban A, Prusiner SB
• Genetics of prion infections.
  Trends in genetics : TIG 1991 Carlson GA, Hsiao K, Oesch B, Westaway D, Prusiner SB
• Acceleration of scrapie in trisomy 16----diploid aggregation chimeras.
  Annals of neurology 1991 Epstein CJ, Foster DB, DeArmond SJ, Prusiner SB
• Molecular biology and transgenetics of prion diseases.
  Critical reviews in biochemistry and molecular biology 1991 Prusiner SB
• Molecular biology of prions causing infectious and genetic encephalopathies of humans as well as scrapie of sheep and BSE of cattle.
  Developments in biological standardization 1991 Prusiner SB
• Molecular genetics and transgenic model of Gertsmann-Sträussler-Scheinker disease.
  Alzheimer disease and associated disorders 1991 Hsiao K, Prusiner SB
• Novel properties and biology of scrapie prions.
  Current topics in microbiology and immunology 1991 Prusiner SB
• Prion biology and diseases.
  Harvey lectures 1991 Prusiner SB
• Prion protein genes: evolutionary and functional aspects.
  Current topics in microbiology and immunology 1991 Oesch B, Westaway D, Prusiner SB
• Search for a putative scrapie genome in purified prion fractions reveals a paucity of nucleic acids.
  The Journal of general virology 1991 Meyer N, Rosenbaum V, Schmidt B, Gilles K, Mirenda C, Groth D, Prusiner SB, Riesner D
• Spontaneous neurodegeneration in transgenic mice with prion protein codon 101 proline----leucine substitution.
  Annals of the New York Academy of Sciences 1991 Hsiao K, Scott M, Foster D, DeArmond SJ, Groth D, Serban H, Prusiner SB
• Ultrastructural studies of prions.
  Current topics in microbiology and immunology 1991 McKinley MP, Prusiner SB
• Spontaneous neurodegeneration in transgenic mice with mutant prion protein.
  Science (New York, N.Y.) 1990 Hsiao KK, Scott M, Foster D, Groth DF, DeArmond SJ, Prusiner SB
• Inherited human prion diseases.
  Neurology 1990 Hsiao K, Prusiner SB
• Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.
  Cell 1990 Prusiner SB, Scott M, Foster D, Pan KM, Groth D, Mirenda C, Torchia M, Yang SL, Serban D, Carlson GA
• Permethylation and tandem mass spectrometry of oligosaccharides having free hexosamine: analysis of the glycoinositol phospholipid anchor glycan from the scrapie prion protein.
  Analytical biochemistry 1990 Baldwin MA, Stahl N, Reinders LG, Gibson BW, Prusiner SB, Burlingame AL
• Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation.
  Proceedings of the National Academy of Sciences of the United States of America 1990 Taraboulos A, Rogers M, Borchelt DR, McKinley MP, Scott M, Serban D, Prusiner SB
• Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie.
  Laboratory investigation; a journal of technical methods and pathology 1990 Snow AD, Wight TN, Nochlin D, Koike Y, Kimata K, DeArmond SJ, Prusiner SB
• Novel structure and genetics of prions causing neurodegeneration in humans and animals.
  Biologicals : journal of the International Association of Biological Standardization 1990 Prusiner SB
• Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein.
  Biochemistry 1990 Stahl N, Baldwin MA, Burlingame AL, Prusiner SB
• Intracellular accumulation of the cellular prion protein after mutagenesis of its Asn-linked glycosylation sites.
  Glycobiology 1990 Rogers M, Taraboulos A, Scott M, Groth D, Prusiner SB
• Link between scrapie and BSE?
  Nature 1990 Westaway D, Prusiner SB
• Identification of cellular proteins binding to the scrapie prion protein.
  Biochemistry 1990 Oesch B, Teplow DB, Stahl N, Serban D, Hood LE, Prusiner SB
• Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C.
  Biochemistry 1990 Stahl N, Borchelt DR, Prusiner SB
• Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells.
  The Journal of cell biology 1990 Taraboulos A, Serban D, Prusiner SB
• Unusual topogenic sequence directs prion protein biogenesis.
  Science (New York, N.Y.) 1990 Lopez CD, Yost CS, Prusiner SB, Myers RM, Lingappa VR
• DNA length polymorphism 5' to the myelin basic protein gene is associated with multiple sclerosis.
  Annals of neurology 1990 Boylan KB, Takahashi N, Paty DW, Sadovnick AD, Diamond M, Hood LE, Prusiner SB
• Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells.
  The Journal of cell biology 1990 Borchelt DR, Scott M, Taraboulos A, Stahl N, Prusiner SB
• Three hamster species with different scrapie incubation times and neuropathological features encode distinct prion proteins.
  Molecular and cellular biology 1990 Lowenstein DH, Butler DA, Westaway D, McKinley MP, DeArmond SJ, Prusiner SB
• Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein.
  Nature 1990 Yost CS, Lopez CD, Prusiner SB, Myers RM, Lingappa VR
• Prion liposomes.
  The Biochemical journal 1990 Gabizon R, Prusiner SB
• Nerve growth factor induces gene expression of the prion protein and beta-amyloid protein precursor in the developing hamster central nervous system.
  Progress in brain research 1990 McKinley MP, Longo FM, Valletta JS, Rahbar F, Neve RL, Prusiner SB, Mobley WC
• Prion diseases of the central nervous system.
  Monographs in pathology 1990 Prusiner SB, DeArmond SJ
• Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins.
  Neurology 1990 Serban D, Taraboulos A, DeArmond SJ, Prusiner SB
• Repetitive DNA (TGGA)n 5' to the human myelin basic protein gene: a new form of oligonucleotide repetitive sequence showing length polymorphism.
  Genomics 1990 Boylan KB, Ayres TM, Popko B, Takahashi N, Hood LE, Prusiner SB
• Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.
  Cell 1989 Scott M, Foster D, Mirenda C, Serban D, Coufal F, Wälchli M, Torchia M, Groth D, Carlson G, DeArmond SJ, Westaway D, Prusiner SB
• Diversity of oligosaccharide structures linked to asparagines of the scrapie prion protein.
  Biochemistry 1989 Endo T, Groth D, Prusiner SB, Kobata A
• Acceleration of scrapie in neonatal Syrian hamsters.
  Neurology 1989 McKinley MP, DeArmond SJ, Torchia M, Mobley WC, Prusiner SB
• Primary structure of prion protein may modify scrapie isolate properties.
  Proceedings of the National Academy of Sciences of the United States of America 1989 Carlson GA, Westaway D, DeArmond SJ, Peterson-Torchia M, Prusiner SB
• Unraveling prion diseases through molecular genetics.
  Trends in neurosciences 1989 Westaway D, Carlson GA, Prusiner SB
• Creutzfeldt-Jakob disease and scrapie prions.
  Alzheimer disease and associated disorders 1989 Prusiner SB
• Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome.
  Nature 1989 Hsiao K, Baker HF, Crow TJ, Poulter M, Owen F, Terwilliger JD, Westaway D, Ott J, Prusiner SB
• Insertion in prion protein gene in familial Creutzfeldt-Jakob disease.
  Lancet (London, England) 1989 Owen F, Poulter M, Lofthouse R, Collinge J, Crow TJ, Risby D, Baker HF, Ridley RM, Hsiao K, Prusiner SB
• Immunoaffinity purification and neutralization of scrapie prions.
  Progress in clinical and biological research 1989 Gabizon R, McKinley MP, Groth D, Westaway D, DeArmond SJ, Carlson GA, Prusiner SB
• PrPSc in scrapie-infected hamster brain is spatially and temporally related to histopathology and infectivity titer.
  Progress in clinical and biological research 1989 De Armond SJ, Gonzales M, Mobley WC, Kon AA, Stern A, Prusiner H, Prusiner SB
• Scrapie prions.
  Annual review of microbiology 1989 Prusiner SB
• Sulfated glycosaminoglycans in amyloid plaques of prion diseases.
  Acta neuropathologica 1989 Snow AD, Kisilevsky R, Willmer J, Prusiner SB, DeArmond SJ
• Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time.
  Molecular and cellular biology 1988 Carlson GA, Goodman PA, Lovett M, Taylor BA, Marshall ST, Peterson-Torchia M, Westaway D, Prusiner SB
• Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain.
  Proceedings of the National Academy of Sciences of the United States of America 1988 Mobley WC, Neve RL, Prusiner SB, McKinley MP
• CNS amyloid proteins in neurodegenerative diseases.
  Neurology 1988 Roberts GW, Lofthouse R, Allsop D, Landon M, Kidd M, Prusiner SB, Crow TJ
• Immunoaffinity purification and neutralization of scrapie prion infectivity.
  Proceedings of the National Academy of Sciences of the United States of America 1988 Gabizon R, McKinley MP, Groth D, Prusiner SB
• Purification and properties of the cellular and scrapie hamster prion proteins.
  European journal of biochemistry 1988 Turk E, Teplow DB, Hood LE, Prusiner SB
• Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da.
  Virology 1988 Bellinger-Kawahara CG, Kempner E, Groth D, Gabizon R, Prusiner SB
• Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins.
  Journal of virology 1988 Butler DA, Scott MR, Bockman JM, Borchelt DR, Taraboulos A, Hsiao KK, Kingsbury DT, Prusiner SB
• Properties of scrapie prion protein liposomes.
  The Journal of biological chemistry 1988 Gabizon R, McKinley MP, Groth DF, Kenaga L, Prusiner SB
• Prion protein gene expression in cultured cells.
  Protein engineering 1988 Scott MR, Butler DA, Bredesen DE, Wälchli M, Hsiao KK, Prusiner SB
• Characterization of prion proteins with monospecific antisera to synthetic peptides.
  Journal of immunology (Baltimore, Md. : 1950) 1988 Barry RA, Vincent MT, Kent SB, Hood LE, Prusiner SB
• Developmental regulation of prion protein mRNA in brain.
  Ciba Foundation symposium 1988 McKinley MP, Lingappa VR, Prusiner SB
• Genetic control of prion incubation period in mice.
  Ciba Foundation symposium 1988 Carlson GA, Westaway D, Goodman PA, Peterson M, Marshall ST, Prusiner SB
• Molecular structure, biology, and genetics of prions.
  Advances in virus research 1988 Prusiner SB
• Novel mechanisms of degeneration of the central nervous system--prion structure and biology.
  Ciba Foundation symposium 1988 Prusiner SB, Stahl N, DeArmond SJ
• Properties of scrapie prion proteins in liposomes and amyloid rods.
  Ciba Foundation symposium 1988 Gabizon R, McKinley MP, Prusiner SB
• Search for a scrapie-specific nucleic acid: a progress report.
  Ciba Foundation symposium 1988 Oesch B, Groth DF, Prusiner SB, Weissmann C
• Prions and neurodegenerative diseases.
  The New England journal of medicine 1987 Prusiner SB
• Evidence for a secretory form of the cellular prion protein.
  Biochemistry 1987 Hay B, Prusiner SB, Lingappa VR
• Immuno-gold localization of prion filaments in scrapie-infected hamster brains.
  Laboratory investigation; a journal of technical methods and pathology 1987 Wiley CA, Burrola PG, Buchmeier MJ, Wooddell MK, Barry RA, Prusiner SB, Lampert PW
• The burden of proof in linking AIDS to scrapie.
  Nature 1987 Braun MJ, Gonda MA, George DG, Bazan JF, Fletterick RJ, Prusiner SB
• Distinct prion proteins in short and long scrapie incubation period mice.
  Cell 1987 Westaway D, Goodman PA, Mirenda CA, McKinley MP, Carlson GA, Prusiner SB
• Scrapie prion protein contains a phosphatidylinositol glycolipid.
  Cell 1987 Stahl N, Borchelt DR, Hsiao K, Prusiner SB
• Purified scrapie prions resist inactivation by procedures that hydrolyze, modify, or shear nucleic acids.
  Virology 1987 Bellinger-Kawahara C, Diener TO, McKinley MP, Groth DF, Smith DR, Prusiner SB
• Changes in the localization of brain prion proteins during scrapie infection.
  Neurology 1987 DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB
• Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.
  Laboratory investigation; a journal of technical methods and pathology 1987 Kitamoto T, Ogomori K, Tateishi J, Prusiner SB
• Scrapie infection diminishes spines and increases varicosities of dendrites in hamsters: a quantitative Golgi analysis.
  Journal of neuropathology and experimental neurology 1987 Hogan RN, Baringer JR, Prusiner SB
• Immunoblotting of Creutzfeldt-Jakob disease prion proteins: host species-specific epitopes.
  Annals of neurology 1987 Bockman JM, Prusiner SB, Tateishi J, Kingsbury DT
• Purified prion proteins and scrapie infectivity copartition into liposomes.
  Proceedings of the National Academy of Sciences of the United States of America 1987 Gabizon R, McKinley MP, Prusiner SB
• DNA length polymorphism located 5' to the human myelin basic protein gene.
  American journal of human genetics 1987 Boylan KB, Takahashi N, Diamond M, Hood LE, Prusiner SB
• Developmental expression of prion protein gene in brain.
  Developmental biology 1987 McKinley MP, Hay B, Lingappa VR, Lieberburg I, Prusiner SB
• Prion diseases and central nervous system degeneration.
  Clinical research 1987 Prusiner SB
• Prions causing nervous system degeneration.
  Laboratory investigation; a journal of technical methods and pathology 1987 Prusiner SB, DeArmond SJ
• AIDS virus and scrapie protein genes.
  Nature 1987 Fernando Bazan J, Fletterick RJ, Prusiner SB
• Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035].
  Molecular and cellular biology 1987 Hay B, Barry RA, Lieberburg I, Prusiner SB, Lingappa VR
• Predicted secondary structure and membrane topology of the scrapie prion protein.
  Protein engineering 1987 Bazan JF, Fletterick RJ, McKinley MP, Prusiner SB
• On the biology of prions.
  Acta neuropathologica 1987 Prusiner SB, Gabizon R, McKinley MP
• Prions causing degenerative neurological diseases.
  Annual review of medicine 1987 Prusiner SB
• Purified scrapie prions resist inactivation by UV irradiation.
  Journal of virology 1987 Bellinger-Kawahara C, Cleaver JE, Diener TO, Prusiner SB
• Prions are novel infectious pathogens causing scrapie and Creutzfeldt-Jakob disease.
  BioEssays : news and reviews in molecular, cellular and developmental biology 1986 Prusiner SB
• Prion-protein immunoreactivity in human transmissible dementias.
  The New England journal of medicine 1986 Roberts GW, Lofthouse R, Brown R, Crow TJ, Barry RA, Prusiner SB
• Vasoactive intestinal peptide stimulates cyclic AMP metabolism in choroid plexus epithelial cells.
  Brain research 1986 Crook RB, Prusiner SB
• Monoclonal antibodies to the cellular and scrapie prion proteins.
  The Journal of infectious diseases 1986 Barry RA, Prusiner SB
• Linkage of prion protein and scrapie incubation time genes.
  Cell 1986 Carlson GA, Kingsbury DT, Goodman PA, Coleman S, Marshall ST, DeArmond S, Westaway D, Prusiner SB
• Amyloid plaques in Creutzfeldt-Jakob disease stain with prion protein antibodies.
  Annals of neurology 1986 Kitamoto T, Tateishi J, Tashima T, Takeshita I, Barry RA, DeArmond SJ, Prusiner SB
• Molecular cloning of a human prion protein cDNA.
  DNA (Mary Ann Liebert, Inc.) 1986 Kretzschmar HA, Stowring LE, Westaway D, Stubblebine WH, Prusiner SB, Dearmond SJ
• Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene.
  Cell 1986 Basler K, Oesch B, Scott M, Westaway D, Wälchli M, Groth DF, McKinley MP, Prusiner SB, Weissmann C
• Molecular characteristics of prion rods purified from scrapie-infected hamster brains.
  The Journal of infectious diseases 1986 McKinley MP, Braunfeld MB, Bellinger CG, Prusiner SB
• Scrapie and cellular prion proteins share polypeptide epitopes.
  The Journal of infectious diseases 1986 Barry RA, Kent SB, McKinley MP, Meyer RK, DeArmond SJ, Hood LE, Prusiner SB
• Separation and properties of cellular and scrapie prion proteins.
  Proceedings of the National Academy of Sciences of the United States of America 1986 Meyer RK, McKinley MP, Bowman KA, Braunfeld MB, Barry RA, Prusiner SB
• Conservation of the cellular gene encoding the scrapie prion protein.
  Nucleic acids research 1986 Westaway D, Prusiner SB
• H2 histamine receptors on the epithelial cells of choroid plexus.
  Journal of neurochemistry 1986 Crook RB, Farber MB, Prusiner SB
• Biology and structure of scrapie prions.
  International review of neurobiology 1986 McKinley MP, Prusiner SB
• Replication of scrapie prions in hamster eyes precedes retinal degeneration.
  Ophthalmic research 1986 Hogan RN, Bowman KA, Baringer JR, Prusiner SB
• Scrapie prion proteins are synthesized in neurons.
  The American journal of pathology 1986 Kretzschmar HA, Prusiner SB, Stowring LE, DeArmond SJ
• Transmission of scrapie in hamsters.
  The Journal of infectious diseases 1985 Prusiner SB, Cochran SP, Alpers MP
• A microangiopathic syndrome of encephalopathy, hearing loss, and retinal arteriolar occlusions.
  Neurology 1985 Monteiro ML, Swanson RA, Coppeto JR, Cuneo RA, DeArmond SJ, Prusiner SB
• Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons.
  Cell 1985 Takahashi N, Roach A, Teplow DB, Prusiner SB, Hood L
• Antibodies to the scrapie protein decorate prion rods.
  Journal of immunology (Baltimore, Md. : 1950) 1985 Barry RA, McKinley MP, Bendheim PE, Lewis GK, DeArmond SJ, Prusiner SB
• Identification of prion amyloid filaments in scrapie-infected brain.
  Cell 1985 DeArmond SJ, McKinley MP, Barry RA, Braunfeld MB, McColloch JR, Prusiner SB
• Scrapie PrP 27-30 is a sialoglycoprotein.
  Journal of virology 1985 Bolton DC, Meyer RK, Prusiner SB
• Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants.
  Proceedings of the National Academy of Sciences of the United States of America 1985 Bendheim PE, Bockman JM, McKinley MP, Kingsbury DT, Prusiner SB
• Creutzfeldt-Jakob disease prion proteins in human brains.
  The New England journal of medicine 1985 Bockman JM, Kingsbury DT, McKinley MP, Bendheim PE, Prusiner SB
• Prions--infectious pathogens causing the spongiform encephalopathies.
  CRC critical reviews in clinical neurobiology 1985 Prusiner SB, Kingsbury DT
• Scrapie and Creutzfeldt-Jakob disease prions.
  Microbiological sciences 1985 Prusiner SB, Barry RA, McKinley MP, Bellinger CG, Meyer RK, DeArmond SJ, Kingsbury DT
• Scrapie prions, brain amyloid, and senile dementia.
  Current topics in cellular regulation 1985 Prusiner SB
• Molecular characteristics of the major scrapie prion protein.
  Biochemistry 1984 Bolton DC, McKinley MP, Prusiner SB
• Bitemporal hypometabolism in Creutzfeldt-Jakob disease measured by positron emission tomography with [18F]-2-fluorodeoxyglucose.
  Journal of computer assisted tomography 1984 Friedland RP, Prusiner SB, Jagust WJ, Budinger TF, Davis RL
• Prions.
  Scientific American 1984 Prusiner SB
• Antibodies to a scrapie prion protein.
  Nature 1984 Bendheim PE, Barry RA, DeArmond SJ, Stites DP, Prusiner SB
• Purification and structural studies of a major scrapie prion protein.
  Cell 1984 Prusiner SB, Groth DF, Bolton DC, Kent SB, Hood LE
• Some speculations about prions, amyloid, and Alzheimer's disease.
  The New England journal of medicine 1984 Prusiner SB
• Hormones and neurotransmitters control cyclic AMP metabolism in choroid plexus epithelial cells.
  Journal of neurochemistry 1984 Crook RB, Farber MB, Prusiner SB
• Prions: novel infectious pathogens.
  Advances in virus research 1984 Prusiner SB
• Retinal degeneration in experimental Creutzfeldt-Jakob disease.
  Laboratory investigation; a journal of technical methods and pathology 1983 Hogan RN, Kingsbury DT, Baringer JR, Prusiner SB
• Scrapie prions aggregate to form amyloid-like birefringent rods.
  Cell 1983 Prusiner SB, McKinley MP, Bowman KA, Bolton DC, Bendheim PE, Groth DF, Glenner GG
• A protease-resistant protein is a structural component of the scrapie prion.
  Cell 1983 McKinley MP, Bolton DC, Prusiner SB
• Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice.
  Cell 1983 Roach A, Boylan K, Horvath S, Prusiner SB, Hood LE
• Replication of the scrapie agent in hamster brain precedes neuronal vacuolation.
  Journal of neuropathology and experimental neurology 1983 Baringer JR, Bowman KA, Prusiner SB
• Genetic control of scrapie and Creutzfeldt-Jakob disease in mice.
  Journal of immunology (Baltimore, Md. : 1950) 1983 Kingsbury DT, Kasper KC, Stites DP, Watson JD, Hogan RN, Prusiner SB
• Resistance of the scrapie agent to inactivation by psoralens.
  Photochemistry and photobiology 1983 McKinley MP, Masiarz FR, Isaacs ST, Hearst JE, Prusiner SB
• Identification of a protein that purifies with the scrapie prion.
  Science (New York, N.Y.) 1982 Bolton DC, McKinley MP, Prusiner SB
• Further purification and characterization of scrapie prions.
  Biochemistry 1982 Prusiner SB, Bolton DC, Groth DF, Bowman KA, Cochran SP, McKinley MP
• Immunological studies of scrapie infection.
  Journal of neuroimmunology 1982 Kasper KC, Stites DP, Bowman KA, Panitch H, Prusiner SB
• Viroids and prions.
  Proceedings of the National Academy of Sciences of the United States of America 1982 Diener TO, McKinley MP, Prusiner SB
• Research on scrapie.
  Lancet (London, England) 1982 Prusiner SB
• Kuru with incubation periods exceeding two decades.
  Annals of neurology 1982 Prusiner SB, Gajdusek C, Alpers MP
• Novel proteinaceous infectious particles cause scrapie.
  Science (New York, N.Y.) 1982 Prusiner SB
• Measurement of the scrapie agent using an incubation time interval assay.
  Annals of neurology 1982 Prusiner SB, Cochran SP, Groth DF, Downey DE, Bowman KA, Martinez HM
• Reversible chemical modification of the scrapie agent.
  Science (New York, N.Y.) 1981 McKinley MP, Masiarz FR, Prusiner SB
• Scrapie agent contains a hydrophobic protein.
  Proceedings of the National Academy of Sciences of the United States of America 1981 Prusiner SB, McKinley MP, Groth DF, Bowman KA, Mock NI, Cochran SP, Masiarz FR
• Culture and characterization of epithelial cells from bovine choroid plexus.
  Journal of neurochemistry 1981 Crook RB, Kasagami H, Prusiner SB
• Membrane populations of bovine choroid plexus: separation by density gradient centrifugation in modified colloidal silica.
  Journal of neurochemistry 1981 Mamelok RD, Macrae DR, Benet LZ, Prusiner SB
• Thiocyanate and hydroxyl ions inactivate the scrapie agent.
  Proceedings of the National Academy of Sciences of the United States of America 1981 Prusiner SB, Groth DF, McKinley MP, Cochran SP, Bowman KA, Kasper KC
• Scrapie-associated particles in postsynaptic processes. Further ultrastructural studies.
  Journal of neuropathology and experimental neurology 1981 Baringer JR, Prusiner SB, Wong JS
• Kinetics of D-glucose transport into renal membrane vesicles: measurements using a vacuum manifold apparatus.
  Journal of biochemical and biophysical methods 1981 Mamelok RD, Macrae DR, Hittelman K, Hoefer JP, Prusiner SB
• Determination of scrapie agent titer from incubation period measurements in hamsters.
  Advances in experimental medicine and biology 1981 Prusiner SB, Cochran SP, Downey DE, Groth DF
• Disorders of glutamate metabolism and neurological dysfunction.
  Annual review of medicine 1981 Prusiner SB
• Progressive retinal degeneration in scrapie-infected hamsters: a light and electron microscopic analysis.
  Laboratory investigation; a journal of technical methods and pathology 1981 Hogan RN, Baringer JR, Prusiner SB
• Toward development of assays for scrapie-specific antibodies.
  Advances in experimental medicine and biology 1981 Kasper KC, Bowman K, Stites DP, Prusiner SB
• Brain tissue from persons dying of Creutzfeldt-Jakob disease causes scrapie-like encephalopathy in goats.
  Annals of neurology 1980 Hadlow WJ, Prusiner SB, Kennedy RC, Race RE
• Gel electrophoresis and glass permeation chromatography of the hamster scrapie agent after enzymatic digestion and detergent extraction.
  Biochemistry 1980 Prusiner SB, Groth DF, Cochran SP, McKinley MP, Masiarz FR
• Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent.
  Biochemistry 1980 Prusiner SB, Groth DF, Cochran SP, Masiarz FR, McKinley MP, Martinez HM
• Biohazards of investigations on the transmissible spongiform encephalopathies.
  Reviews of infectious diseases 1980 Chatigny MA, Prusiner SB
• Experimental scrapie in the mouse: electrophoretic and sedimentation properties of the partially purified agent.
  Journal of neurochemistry 1980 Prusiner SB, Garfin DE, Cochran SP, McKinley MP, Groth DF, Hadlow WJ, Race RE, Eklund CM
• Separation of membrane-bound gamma-glutamyl transpeptidase from brush border transport and enzyme activities.
  Biochemistry 1980 Mamelok RD, Groth DF, Prusiner SB
• Electrophoretic properties of the scrapie agent in agarose gels.
  Proceedings of the National Academy of Sciences of the United States of America 1980 Prusiner SB, Groth DF, Bildstein C, Masiarz FR, McKinley MP, Cochran SP
• Slow viruses: molecular properties of the agents causing scrapie in mice and hamsters.
  Progress in clinical and biological research 1980 Prusiner SB, Cochran SP, Baringer JR, Groth D, Masiarz F, McKinley M, Bildstein C, Garfin D, Hadlow WJ, Race RE, Eklund CM
• Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge.
  Applied and environmental microbiology 1979 Chatigny MA, Dunn S, Ishimaru K, Eagleson JA, Prusiner SB
• Partial purification and evidence for multiple molecular forms of the scrapie agent.
  Biochemistry 1978 Prusiner SB, Hadlow WJ, Garfin DE, Cochran SP, Baringer JR, Race RE, Eklund CM
• Sedimentation characteristics of the scrapie agent from murine spleen and brain.
  Biochemistry 1978 Prusiner SB, Hadlow WJ, Eklund CM, Race RE, Cochran SP
• Experimental scrapie in mice: ultrastructural observations.
  Annals of neurology 1978 Baringer JR, Prusiner SB
• Mitogen stimulation of splenocytes from mice infected with scrapie agent.
  The Journal of infectious diseases 1978 Garfin DE, Stites DP, Perlman JD, Cochran SP, Prusiner SB
• Preservation by freezing of glucose and alanine transport into kidney membrane vesicles.
  Analytical biochemistry 1978 Hittelman K, Mamelok RD, Prusiner SB
• Modulation of gamma-glutamyl transpeptidase activity from bovine choroid plexus.
  Journal of neurochemistry 1978 Prusiner PE, Prusiner SB
• Partial purification and kinetics of gamma-glutamyl transpeptidase from bovine choroid plexus.
  Journal of neurochemistry 1978 Prusiner PE, Prusiner SB
• Suppression of polyclonal B cell activation in scrapie-infected C3H/HeJ mice.
  Journal of immunology (Baltimore, Md. : 1950) 1978 Garfin DE, Stites DP, Zitnik LA, Prusiner SB
• An approach to the isolation of biological particles using sedimentation analysis.
  The Journal of biological chemistry 1978 Prusiner SB
• Evidence for hydrophobic domains on the surface of the scrapie agent.
  Transactions of the American Neurological Association 1978 Prusiner SB, Garfin DE, Cochran SP, Baringer JR, Hadlow WJ, Eklund CM, Race RE
• Sedimentation properties of the scrapie agent.
  Proceedings of the National Academy of Sciences of the United States of America 1977 Prusiner SB, Hadlow WJ, Eklund CM, Race RE
• Comparative studies on membranes from bovine choroid plexus and rat kidney cortex.
  Life sciences 1977 Kirk G, Prusiner SB
• Carotidynia.
  Neurology 1977 Raskin NH, Prusiner S
• A novel mechanism for group translocation: substrate-product reutilization by gamma-glutamyl transpeptidase in peptide and amino acid transport.
  Journal of cellular physiology 1976 Prusiner S, Doak CW, Kirk G
• Regulation of glutaminase B in Escherichia coli. I. Purification, properties, and cold lability.
  The Journal of biological chemistry 1976 Prusiner S, Davis JN, Stadtman ER
• Regulation of glutaminase B in Escherichia coli. II. Modulaltion of activity by carbosylate and borate ions.
  The Journal of biological chemistry 1976 Prusiner S, Stadtman ER
• Regulation of glutaminase B in Escherichia coli. III. Control by nucleotides and divalent cations.
  The Journal of biological chemistry 1976 Prusiner S, Stadtman ER
• Regulation of glutaminase levels in Escherichia coli.
  Journal of bacteriology 1975 Prusiner S
• Regulation of glutamine synthetase from Bacillus subtilis by divalent cations, feedback inhibitors, and L-glutamine.
  The Journal of biological chemistry 1974 Deuel TF, Prusiner S
• Stain for glutaminase activity.
  Analytical biochemistry 1973 Davis JN, Prusiner S
• Adenosine 3':5'-cyclic monophosphate control of the enzymes of glutamine metabolism in Escherichia coli.
  Proceedings of the National Academy of Sciences of the United States of America 1972 Prusiner S, Miller RE, Valentine RC
• On the regulation of glutaminase in E. coli: metabolite control.
  Biochemical and biophysical research communications 1971 Prusiner S, Stadtman ER
• Vacuum manifold for rapid assay of enzymes using radioactive tracers and ion exchange chromatography.
  The Review of scientific instruments 1971 Prusiner SB, Milner LS, Long CW, Myers ML
• A rapid radioactive assay for glutamine synthetase, glutaminase, asparagine synthetase, and asparaginase.
  Analytical biochemistry 1970 Prusiner S, Milner L
• Metabolic control in isolated brown fat cells.
  Lipids 1970 Lindberg O, Prusiner SB, Cannon B, Ching TM, Eisenhardt RH
• Spectroscopic evidence for the control of respiration prior to phosphorylation in hamster brown fat cells.
  The Journal of biological chemistry 1970 Prusiner S
• Control of metabolism in brown adipose tissue.
  Lipids 1970 Williamson JR, Prusiner S, Olson MS, Fukami M
• [Energetic disturbance of cation transport as a cause of intracellular brain edema].
  Acta neurochirurgica 1970 Reulen HJ, Steude U, Brendel W, Hilber C, Prusiner S
• Hypothermic protection against cerebral edema of ischemia.
  Archives of neurology 1968 Prusiner S, Wolfson SK
• Oxidative metabolism in cells isolated from brown adipose tissue. 2. Catecholamine regulated respiratory control.
  European journal of biochemistry 1968 Prusiner SB, Cannon B, Ching TM, Lindberg O
• Thermodynamic cosiderations of mammalian thermogenesis.
  Nature 1968 Prusiner S, Poe M
• Oxidative metabolism in cells isolated from brown adipose tissue. 1. Catecholamine and fatty acid stimulation of respiration.
  European journal of biochemistry 1968 Prusiner SB, Cannon B, Lindberg O
• The regulation of oxidative metabolism of isolated brown fat cells.
  Biochemical and biophysical research communications 1968 Prusiner SB, Eisenhardt RH, Rylander E, Lindberg O
• Pyridine nucleotide changes during thermogenesis in brown fat tissue in vivo.
  Archives of biochemistry and biophysics 1968 Prusiner S, Williamson JR, Chance B, Paddle BM
• Relationship of acidemia to cerebral edema.
  Archives of surgery (Chicago, Ill. : 1960) 1965 Prusiner SB, Moskovitz PA, Wolfson SK