Srividhya Swaminathan, PhD
Postdoctoral Scholar
Pediatrics
School of Medicine

Education & Training

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• Ph.D Immunology The University of Queensland 2024
• M.Tech Biotechnology Vellore Institute of Technology 2018
• B.Tech Biotechnology SASTRA University 2016

Interests

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• Infectious diseases
• Immunology
• Virology
• Vaccines
• Maternal-Fetal Health
• T cells
• Immunotherapy

Websites

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• Prahl Lab (prahllab.ucsf.edu)

Publications (8)

Top publication keywords:
Sequence AlignmentHLA AntigensEpitopes, T-LymphocyteAmino Acid SequenceCD8-Positive T-LymphocytesAntibodies, NeutralizingSpike Glycoprotein, CoronavirusAntibodies, ViralEpitope MappingCross ReactionsImmunotherapy, AdoptiveImmunodominant EpitopesT-LymphocytesConserved SequenceCoronavirus

• Allogeneic 'off-the-shelf' SARS-CoV-2-specific adoptive T-cell therapy for refractory viral infection and end organ disease.
  Clinical & translational immunology 2025 Henden AS, Lineburg KE, Panikkar A, Mahajan A, Nelles R, Wright E, Crooks P, Raju J, Le Texier L, Swaminathan S, Beagley L, Best S, Solomon M, Reddiex H, Kennedy G, Tey SK, Neller MA, Khanna R, Smith …
• Breakthrough SARS-COV-2 infection induces broad anti-viral T cell immunity.
  iScience 2023 Lineburg KE, Crooks P, Raju J, Le Texier L, Khaledi P, Berry K, Swaminathan S, Panikkar A, Rehan S, Guppy-Coles K, Neller MA, Khanna R, Smith C
• Ablation of CD8+ T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3.
  Nature communications 2022 Swaminathan S, Lineburg KE, Panikkar A, Raju J, Murdolo LD, Szeto C, Crooks P, Le Texier L, Rehan S, Dewar-Oldis MJ, Barnard PJ, Ambalathingal GR, Neller MA, Short KR, Gras S, Khanna R, Smith C
• Limited Recognition of Highly Conserved Regions of SARS-CoV-2.
  Microbiology spectrum 2022 Swaminathan S, Lineburg KE, Ambalathingal GR, Crooks P, Grant EJ, Mohan SV, Raju J, Panikkar A, Le Texier L, Tong ZWM, Chew KY, Neller MA, Short KR, Gowda H, Gras S, Khanna R, Smith C
• SARS-CoV-2-specific T cells generated for adoptive immunotherapy are capable of recognizing multiple SARS-CoV-2 variants.
  PLoS pathogens 2022 Panikkar A, Lineburg KE, Raju J, Chew KY, Ambalathingal GR, Rehan S, Swaminathan S, Crooks P, Le Texier L, Beagley L, Best S, Solomon M, Matthews KK, Srihari S, Neller MA, Short KR, Khanna R, Smith C
• Rapid whole-blood assay to detect SARS-CoV-2-specific memory T-cell immunity following a single dose of AstraZeneca ChAdOx1-S COVID-19 vaccine.
  Clinical & translational immunology 2021 Lineburg KE, Neller MA, Ambalathingal GR, Le Texier L, Raju J, Swaminathan S, Lekieffre L, Smith C, Rehan S, Crooks P, Panikkar A, Srihari S, Khanna R, Smith C
• CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.
  Immunity 2021 Lineburg KE, Grant EJ, Swaminathan S, Chatzileontiadou DSM, Szeto C, Sloane H, Panikkar A, Raju J, Crooks P, Rehan S, Nguyen AT, Lekieffre L, Neller MA, Tong ZWM, Jayasinghe D, Chew KY, Lobos CA, …
• Rapid detection of SARS-CoV-2-specific memory T-cell immunity in recovered COVID-19 cases.
  Clinical & translational immunology 2020 Lineburg KE, Srihari S, Altaf M, Swaminathan S, Panikkar A, Raju J, Crooks P, Ambalathingal GR, Martins JP, Matthews KK, Neller MA, Khanna R, Smith C