Sophie Patzek, MD
Assistant Professor
Medicine
School of Medicine

Education & Training

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• Fellowship Endocrinology and Metabolism University of California San Francisco 2019
• Residency Internal Medicine University of California San Diego 2016
• MD School of Medicine University of Texas Health Science Center at San Antonio 2013
• BS Biochemistry and Molecular Biology University of California Santa Cruz

Grants and Projects

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• Diabetes, Endocrinology & Metabolism Training Grant, NIH, 1981-2022
• Investigating the interactions between epithelial and stromal cells during pancreatic development, Kraft Fellowship, 2019-2020

Publications (15)

Top publication keywords:
Graves OphthalmopathyDiabetes Mellitus, Type 1Glucagon-Secreting CellsInsulin-Secreting CellsInsulinHypophysitisInsulinsEnteral NutritionDiabetes MellitusGlucoseGranulomatosis with PolyangiitisHyperglycemiaInsulin, Regular, HumanDiabetes Mellitus, Type 2Insulin Infusion Systems

• Use of Open-Source Automated Insulin Delivery Systems in Pregnancies With Type 1 Diabetes.
  Journal of diabetes science and technology 2023 Sobhani NC, Killion M, Patzek S
• Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia.
  iScience 2023 Patzek S, Liu Z, de la O S, Chang S, Byrnes LE, Zhang X, Ornitz DM, Sneddon JB
• Automated Self-Adjusting Subcutaneous Insulin Algorithm for Patients NPO or on TPN or Enteral Feedings.
  Journal of diabetes science and technology 2020 Patzek S, MacMaster HW, Rov-Ikpah E, San Luis C, Johnson C, Juttukonda V, Rushakoff RJ
• Teprotumumab for Active Thyroid Eye Disease.
  The New England journal of medicine 2020 Kim S, Patzek S
• Beta Living through Alpha Cells.
  Cell stem cell 2019 Patzek S, Sneddon JB

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• Granulomatosis with Polyangiitis Presenting as Hypophysitis.
  The American journal of medicine 2018 Chu JN, Goglin S, Patzek S, Brondfield S
• Physiologic and pathophysiologic roles of extra renal CYP27b1: Case report and review.
  Bone reports 2018 Bikle DD, Patzek S, Wang Y
• Mechanisms of triglyceride accumulation in activated macrophages.
  Journal of leukocyte biology 2012 Feingold KR, Shigenaga JK, Kazemi MR, McDonald CM, Patzek SM, Cross AS, Moser A, Grunfeld C
• FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis.
  Endocrinology 2012 Feingold KR, Grunfeld C, Heuer JG, Gupta A, Cramer M, Zhang T, Shigenaga JK, Patzek SM, Chan ZW, Moser A, Bina H, Kharitonenkov A
• Endotoxin, zymosan, and cytokines decrease the expression of the transcription factor, carbohydrate response element binding protein, and its target genes.
  Innate immunity 2010 Feingold KR, Shigenaga JK, Patzek SM, Chui LG, Moser A, Grunfeld C
• The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men.
  Journal of acquired immune deficiency syndromes (1999) 2009 Lee GA, Schwarz JM, Patzek S, Kim S, Dyachenko A, Wen M, Mulligan K, Schambelan M, Grunfeld C
• ADRP/ADFP and Mal1 expression are increased in macrophages treated with TLR agonists.
  Atherosclerosis 2009 Feingold KR, Kazemi MR, Magra AL, McDonald CM, Chui LG, Shigenaga JK, Patzek SM, Chan ZW, Londos C, Grunfeld C
• Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm.
  Journal of lipid research 2009 Feingold KR, Moser A, Patzek SM, Shigenaga JK, Grunfeld C
• A genetic screen for suppressors of a mutated 5' splice site identifies factors associated with later steps of spliceosome assembly.
  Genetics 2009 Dassah M, Patzek S, Hunt VM, Medina PE, Zahler AM
• Inflammation stimulates the expression of PCSK9.
  Biochemical and biophysical research communications 2008 Feingold KR, Moser AH, Shigenaga JK, Patzek SM, Grunfeld C