Sophia Vinogradov, MD
Professor
Psychiatry
School of Medicine

She received her M.D. from Wayne State University School of Medicine, obtained her psychiatry residency training at Stanford University School of Medicine, where she served as Chief Resident, and completed a Psychiatric Neurosciences Research Fellowship at the Palo Alto VA Medical Center and Stanford University.

Clinical Expertise: Psychopharmacologic treatment of serious mental disorders. Diagnosis and treatment of psychotic disorders. Application of principles of cognitive and neuroscience to understanding of clinical disorders.

Educational Expertise: Brain, Mind, and Behavior—integrated neuroscience/neurology/psychiatry course for medical students; fundamentals of cognitive neuroscience as applied to human psychopathology and clinical psychopharmacology.

Research Areas: Dr. Vinogradov directs a translational clinical neuroscience laboratory that focuses on cognitive dysfunction in schizophrenia. In collaboration with basic neuroscientist, Michael Merzenich, Ph.D., she studies neuroscience-guided computerized cognitive training exercises for patients with schizophrenia that aim to drive enduring plastic changes in cortical processing. Dr. Vinogradov uses MEG and fMRI methods to probe the brain changes in both early sensory processing and higher-order cognitive operations in subjects who undergo this cognitive training. She is also examining changes in serum biomarkers (BDNF, D-serine) as a response to training. More recently, Dr. Vinogradov has begun to apply these methods to the study of adolescents who are prodromal for schizophrenia and young adults in early psychosis, with the goal of delaying or preventing the onset of a deteriorating psychiatric illness.

• Cortical and subcortical brain morphometry abnormalities in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia.
  Psychiatry research. Neuroimaging 2023 Hua JPY, Loewy RL, Stuart B, Fryer SL, Niendam TA, Carter CS, Vinogradov S, Mathalon DH
• Rich-club connectivity and structural connectome organization in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia.
  Schizophrenia research 2023 Hua JPY, Cummings J, Roach BJ, Fryer SL, Loewy RL, Stuart BK, Ford JM, Vinogradov S, Mathalon DH
• Abnormal Information Flow in Schizophrenia Is Linked to Psychosis.
  Schizophrenia bulletin 2022 Jia Y, Kudo K, Hinkley LBN, Fisher M, Vinogradov S, Nagarajan S, Subramaniam K
• Predictive models for social functioning in healthy young adults: A machine learning study integrating neuroanatomical, cognitive, and behavioral data.
  Social neuroscience 2022 Miley K, Michalowski M, Yu F, Leng E, McMorris BJ, Vinogradov S
• Psychosis spectrum illnesses as disorders of prefrontal critical period plasticity.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2022 Vinogradov S, Chafee MV, Lee E, Morishita H
• Etiopathogenic Models of Psychosis Spectrum Illnesses Must Resolve Four Key Features.
  Biological psychiatry 2022 Vinogradov S, Hamid AA, Redish AD
• Changes in emotion processing and social cognition with auditory versus visual neuroscience-informed cognitive training in individuals with schizophrenia.
  Schizophrenia research 2022 Scoriels L, Genaro LT, Keffer S, Guimarães AL, Barros-Dumas B, Mororó LG, Biagioni T, Lucena C, da Hora TR, Sahakian BJ, Fisher M, Vinogradov S, Panizzutti R
• Biased and inflexible interpretations of ambiguous social situations: Associations with eating disorder symptoms and socioemotional functioning.
  The International journal of eating disorders 2022 Bronstein MV, Everaert J, Kummerfeld E, Haynos AF, Vinogradov S
• Durable Cognitive Gains and Symptom Improvement Are Observed in Individuals With Recent-Onset Schizophrenia 6 Months After a Randomized Trial of Auditory Training Completed Remotely.
  Schizophrenia bulletin 2022 Loewy R, Fisher M, Ma S, Carter C, Ragland JD, Niendam TA, Stuart B, Schlosser D, Amirfathi F, Yohannes S, Vinogradov S
• Eliminate schizophrenia.
  Schizophrenia research 2022 Zick JL, Staglin B, Vinogradov S
• Computational validity: using computation to translate behaviours across species.
  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2021 Redish AD, Kepecs A, Anderson LM, Calvin OL, Grissom NM, Haynos AF, Heilbronner SR, Herman AB, Jacob S, Ma S, Vilares I, Vinogradov S, Walters CJ, Widge AS, Zick JL, Zilverstand A
• Willingness to vaccinate against SARS-CoV-2: The role of reasoning biases and conspiracist ideation.
  Vaccine 2021 Bronstein MV, Kummerfeld E, MacDonald A, Vinogradov S
• Causal pathways to social and occupational functioning in the first episode of schizophrenia: uncovering unmet treatment needs.
  Psychological medicine 2021 Miley K, Meyer-Kalos P, Ma S, Bond DJ, Kummerfeld E, Vinogradov S
• Author Correction: Multivariate pattern analysis of brain structure predicts functional outcome after auditory-based cognitive training interventions.
  NPJ schizophrenia 2021 Kambeitz-Ilankovic L, Vinogradov S, Wenzel J, Fisher M, Haas SS, Betz L, Penzel N, Nagarajan S, Koutsouleris N, Subramaniam K
• Multivariate pattern analysis of brain structure predicts functional outcome after auditory-based cognitive training interventions.
  NPJ schizophrenia 2021 Kambeitz-Ilankovic L, Vinogradov S, Wenzel J, Fisher M, Haas SS, Betz L, Penzel N, Nagarajan S, Koutsouleris N, Subramaniam K
• Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis.
  JAMA psychiatry 2021 ENIGMA Clinical High Risk for Psychosis Working Group, Jalbrzikowski M, Hayes RA, Wood SJ, Nordholm D, Zhou JH, Fusar-Poli P, Uhlhaas PJ, Takahashi T, Sugranyes G, Kwak YB, Mathalon DH, Katagiri N, …
• A Neural Biomarker for Hallucinations: Medial Prefrontal Aberrations in Neural Connectivity Predict Self-Agency Deficits and Hallucination Severity in Schizophrenia.
  Journal of brain research 2021 Haas SS, Hinkley LBN, Fisher M, Vinogradov S, Nagarajan S, Subramaniam K
• Testing a Novel Web-Based Neurocognitive Battery in the General Community: Validation and Usability Study.
  Journal of medical Internet research 2021 Capizzi R, Fisher M, Biagianti B, Ghiasi N, Currie A, Fitzpatrick K, Albertini N, Vinogradov S
• Auditory discrimination and frequency modulation learning in schizophrenia patients: amphetamine within-subject dose response and time course.
  Psychological medicine 2021 Swerdlow NR, Bhakta SG, Talledo J, Benster L, Kotz J, Vinogradov S, Molina JL, Light GA
• Response to targeted cognitive training may be neuroprotective in patients with early schizophrenia.
  Psychiatry research. Neuroimaging 2021 Ramsay IS, Fryer S, Roach BJ, Boos A, Fisher M, Loewy R, Ford JM, Vinogradov S, Mathalon DH
• Online Social Cognition Training in Schizophrenia: A Double-Blind, Randomized, Controlled Multi-Site Clinical Trial.
  Schizophrenia bulletin 2021 Nahum M, Lee H, Fisher M, Green MF, Hooker CI, Ventura J, Jordan JT, Rose A, Kim SJ, Haut KM, Merzenich MM, Vinogradov S
• Targeting Cognition and Motivation in Coordinated Specialty Care for Early Psychosis: A Grant Report.
  Journal of psychiatry and brain science 2020 Roisum R, Jenkins D, Fisher M, Currie A, Ma S, Lindgren C, Meyer-Kalos P, Vinogradov S
• Specificity and Durability of Changes in Auditory Processing Efficiency After Targeted Cognitive Training in Individuals With Recent-Onset Psychosis.
  Frontiers in psychiatry 2020 Biagianti B, Fisher M, Loewy R, Brandrett B, Ordorica C, LaCross K, Schermitzler B, McDonald M, Ramsay I, Vinogradov S
• Deficits in Auditory and Visual Sensory Discrimination Reflect a Genetic Liability for Psychosis and Predict Disruptions in Global Cognitive Functioning.
  Frontiers in psychiatry 2020 Ramsay IS, Schallmo MP, Biagianti B, Fisher M, Vinogradov S, Sponheim SR
• Randomized Controlled Trial Testing Mobile-Based Attention-Bias Modification for Posttraumatic Stress Using Personalized Word Stimuli.
  Clinical psychological science : a journal of the Association for Psychological Science 2020 Niles AN, Woolley JD, Tripp P, Pesquita A, Vinogradov S, Neylan TC, O'Donovan A
• The Visual Word Form Area compensates for auditory working memory dysfunction in schizophrenia.
  Scientific reports 2020 Herman AB, Brown EG, Dale CL, Hinkley LB, Subramaniam K, Houde JF, Fisher M, Vinogradov S, Nagarajan SS
• Auditory versus visual neuroscience-informed cognitive training in schizophrenia: Effects on cognition, symptoms and quality of life.
  Schizophrenia research 2020 Scoriels L, Genaro LT, Mororó LGC, Keffer S, Guimarães ALDV, Ribeiro PVS, Tannos FM, Novaes C, França AI, Goldenstein N, Sahakian BJ, Cavalcanti MT, Fisher M, Vinogradov S, Panizzutti R
• Cognitive Training for Very High Risk Incarcerated Adolescent Males.
  Frontiers in psychiatry 2020 Rowlands A, Fisher M, Mishra J, Nahum M, Brandrett B, Reinke M, Caldwell M, Kiehl KA, Vinogradov S
• Cognitive Control Errors in Nonhuman Primates Resembling Those in Schizophrenia Reflect Opposing Effects of NMDA Receptor Blockade on Causal Interactions Between Cells and Circuits in Prefrontal and Parietal Cortices.
  Biological psychiatry. Cognitive neuroscience and neuroimaging 2020 Kummerfeld E, Ma S, Blackman RK, DeNicola AL, Redish AD, Vinogradov S, Crowe DA, Chafee MV
• Early- Versus Adult-Onset Schizophrenia as a Predictor of Response to Neuroscience-Informed Cognitive Training.
  The Journal of clinical psychiatry 2020 Puig O, Fisher M, Loewy R, Miley K, Ramsay IS, Carter CS, Ragland JD, Niendam T, Vinogradov S
• Increased global cognition correlates with increased thalamo-temporal connectivity in response to targeted cognitive training for recent onset schizophrenia.
  Schizophrenia research 2020 Ramsay IS, Roach BJ, Fryer S, Fisher M, Loewy R, Ford JM, Vinogradov S, Mathalon DH
• Improvement on visual cognitive training exercises in schizophrenia is present but less robust than in healthy individuals.
  Schizophrenia research 2020 Surti TS, Vinogradov S, Bell MD, Wexler BE
• Standardizing Measures for Early Psychosis: What Are Our Goals?
  Biological psychiatry. Cognitive neuroscience and neuroimaging 2020 Vinogradov S
• Six month durability of targeted cognitive training supplemented with social cognition exercises in schizophrenia.
  Schizophrenia research. Cognition 2019 Miley K, Fisher M, Nahum M, Howard E, Rowlands A, Brandrett B, Woolley J, Hooker CI, Biagianti B, Ramsay I, Vinogradov S
• Intervention-specific patterns of cortical function plasticity during auditory encoding in people with schizophrenia.
  Schizophrenia research 2019 Dale CL, Brown EG, Herman AB, Hinkley LBN, Subramaniam K, Fisher M, Vinogradov S, Nagarajan SS
• Multi-outcome meta-analysis (MOMA) of cognitive remediation in schizophrenia: Revisiting the relevance of human coaching and elucidating interplay between multiple outcomes.
  Neuroscience and biobehavioral reviews 2019 Kambeitz-Ilankovic L, Betz LT, Dominke C, Haas SS, Subramaniam K, Fisher M, Vinogradov S, Koutsouleris N, Kambeitz J
• Has the Time Come for Cognitive Remediation in Schizophrenia…Again?
  The American journal of psychiatry 2019 Vinogradov S
• Neuroplasticity and dysplasticity processes in schizophrenia.
  Schizophrenia research 2019 Morishita H, Vinogradov S
• Disparities in Bladder Cancer Treatment and Survival Amongst Elderly Patients with a Pre-existing Mental Illness.
  European urology focus 2019 Sathianathen NJ, Fan Y, Jarosek SL, Konety I, Weight CJ, Vinogradov S, Konety BR
• Development and testing of a web-based battery to remotely assess cognitive health in individuals with schizophrenia.
  Schizophrenia research 2019 Biagianti B, Fisher M, Brandrett B, Schlosser D, Loewy R, Nahum M, Vinogradov S
• Efference copy/corollary discharge function and targeted cognitive training in patients with schizophrenia.
  International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2018 Roach BJ, Ford JM, Biagianti B, Hamilton HK, Ramsay IS, Fisher M, Loewy R, Vinogradov S, Mathalon DH
• Validation of the MUSIC Model of Motivation Inventory for use with cognitive training for schizophrenia spectrum disorders: A multinational study.
  Schizophrenia research 2018 Hansen MC, Jones BD, Eack SM, Glenthøj LB, Ikezawa S, Iwane T, Kidd SA, Lepage M, Lindenmayer JP, Ljuri I, Maida K, Matsuda Y, Nakagome K, Nordentoft M, Ozog V, Penney D, Saperstein AM, Sunaga A, …
• Blood Levels of Glutamate and Glutamine in Recent Onset and Chronic Schizophrenia.
  Frontiers in psychiatry 2018 Madeira C, Alheira FV, Calcia MA, Silva TCS, Tannos FM, Vargas-Lopes C, Fisher M, Goldenstein N, Brasil MA, Vinogradov S, Ferreira ST, Panizzutti R
• A randomized controlled trial comparing a "bottom-up" and "top-down" approach to cognitive training in schizophrenia.
  Journal of psychiatric research 2018 Jahshan C, Vinogradov S, Wynn JK, Hellemann G, Green MF
• Efficacy of PRIME, a Mobile App Intervention Designed to Improve Motivation in Young People With Schizophrenia.
  Schizophrenia bulletin 2018 Schlosser DA, Campellone TR, Truong B, Etter K, Vergani S, Komaiko K, Vinogradov S
• Targeted cognitive training improves auditory and verbal outcomes among treatment refractory schizophrenia patients mandated to residential care.
  Schizophrenia research 2018 Thomas ML, Bismark AW, Joshi YB, Tarasenko M, Treichler EBH, Hochberger WC, Zhang W, Nungaray J, Sprock J, Cardoso L, Tiernan K, Attarha M, Braff DL, Vinogradov S, Swerdlow N, Light GA
• Childhood trauma and clinical high risk for psychosis.
  Schizophrenia research 2018 Loewy RL, Corey S, Amirfathi F, Dabit S, Fulford D, Pearson R, Hua JPY, Schlosser D, Stuart BK, Mathalon DH, Vinogradov S
• Association between increased serum d-serine and cognitive gains induced by intensive cognitive training in schizophrenia.
  Schizophrenia research 2018 Panizzutti R, Fisher M, Garrett C, Man WH, Sena W, Madeira C, Vinogradov S
• Auditory System Target Engagement During Plasticity-Based Interventions in Schizophrenia: A Focus on Modulation of N-Methyl-D-Aspartate-Type Glutamate Receptor Function.
  Biological psychiatry. Cognitive neuroscience and neuroimaging 2018 Kantrowitz JT, Swerdlow NR, Dunn W, Vinogradov S
• Model selection and prediction of outcomes in recent onset schizophrenia patients who undergo cognitive training.
  Schizophrenia research. Cognition 2017 Ramsay IS, Ma S, Fisher M, Loewy RL, Ragland JD, Niendam T, Carter CS, Vinogradov S
• Response to Targeted Cognitive Training Correlates with Change in Thalamic Volume in a Randomized Trial for Early Schizophrenia.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2017 Ramsay IS, Fryer S, Boos A, Roach BJ, Fisher M, Loewy R, Vinogradov S, Mathalon DH
• Feasibility and preliminary efficacy of remotely delivering cognitive training to people with schizophrenia using tablets.
  Schizophrenia research. Cognition 2017 Biagianti B, Fisher M, Howard L, Rowlands A, Vinogradov S, Woolley J
• White matter microstructure predicts cognitive training-induced improvements in attention and executive functioning in schizophrenia.
  Schizophrenia research 2017 Subramaniam K, Gill J, Fisher M, Mukherjee P, Nagarajan S, Vinogradov S
• Amphetamine Enhances Gains in Auditory Discrimination Training in Adult Schizophrenia Patients.
  Schizophrenia bulletin 2017 Swerdlow NR, Tarasenko M, Bhakta SG, Talledo J, Alvarez AI, Hughes EL, Rana B, Vinogradov S, Light GA
• Trait aspects of auditory mismatch negativity predict response to auditory training in individuals with early illness schizophrenia.
  Neuropsychiatric electrophysiology 2017 Biagianti B, Roach BJ, Fisher M, Loewy R, Ford JM, Vinogradov S, Mathalon DH
• The feasibility, acceptability, and outcomes of PRIME-D: A novel mobile intervention treatment for depression.
  Depression and anxiety 2017 Schlosser DA, Campellone TR, Truong B, Anguera JA, Vergani S, Vinogradov S, Arean P
• Supplementing intensive targeted computerized cognitive training with social cognitive exercises for people with schizophrenia: An interim report.
  Psychiatric rehabilitation journal 2017 Fisher M, Nahum M, Howard E, Rowlands A, Brandrett B, Kermott A, Woolley J, Vinogradov S
• Intranasal oxytocin increases facial expressivity, but not ratings of trustworthiness, in patients with schizophrenia and healthy controls.
  Psychological medicine 2017 Woolley JD, Chuang B, Fussell C, Scherer S, Biagianti B, Fulford D, Mathalon DH, Vinogradov S
• Neural mechanisms of mood-induced modulation of reality monitoring in schizophrenia.
  Cortex; a journal devoted to the study of the nervous system and behavior 2017 Subramaniam K, Ranasinghe KG, Mathalon D, Nagarajan S, Vinogradov S
• Examining the reliability and validity of the Clinical Assessment Interview for Negative Symptoms within the Management of Schizophrenia in Clinical Practice (MOSAIC) multisite national study.
  Schizophrenia research 2017 Blanchard JJ, Bradshaw KR, Garcia CP, Nasrallah HA, Harvey PD, Casey D, Csoboth CT, Hudson JI, Julian L, Lentz E, Nuechterlein KH, Perkins DO, Skale TG, Snowden LR, Tandon R, Tek C, Velligan D, …
• Association of Sensory Processing With Higher-Order Cognition and Functioning in Schizophrenia: Mapping the World.
  JAMA psychiatry 2017 Vinogradov S, Nagarajan S
• Creating Live Interactions to Mitigate Barriers (CLIMB): A Mobile Intervention to Improve Social Functioning in People With Chronic Psychotic Disorders.
  JMIR mental health 2016 Biagianti B, Schlosser D, Nahum M, Woolley J, Vinogradov S
• Neural Mechanisms of Positive Mood Induced Modulation of Reality Monitoring.
  Frontiers in human neuroscience 2016 Subramaniam K, Gill J, Slattery P, Shastri A, Mathalon DH, Nagarajan S, Vinogradov S
• Engagement with the auditory processing system during targeted auditory cognitive training mediates changes in cognitive outcomes in individuals with schizophrenia.
  Neuropsychology 2016 Biagianti B, Fisher M, Neilands TB, Loewy R, Vinogradov S
• Enhancing Cognitive Training Through Aerobic Exercise After a First Schizophrenia Episode: Theoretical Conception and Pilot Study.
  Schizophrenia bulletin 2016 Nuechterlein KH, Ventura J, McEwen SC, Gretchen-Doorly D, Vinogradov S, Subotnik KL
• The effects of intranasal oxytocin in opioid-dependent individuals and healthy control subjects: a pilot study.
  Psychopharmacology 2016 Woolley JD, Arcuni PA, Stauffer CS, Fulford D, Carson DS, Batki S, Vinogradov S
• Feasibility of PRIME: A Cognitive Neuroscience-Informed Mobile App Intervention to Enhance Motivated Behavior and Improve Quality of Life in Recent Onset Schizophrenia.
  JMIR research protocols 2016 Schlosser D, Campellone T, Kim D, Truong B, Vergani S, Ward C, Vinogradov S
• Neuroscience-informed Auditory Training in Schizophrenia: A Final Report of the Effects on Cognition and Serum Brain-Derived Neurotrophic Factor.
  Schizophrenia research. Cognition 2016 Fisher M, Mellon SH, Wolkowitz O, Vinogradov S
• Intensive Auditory Cognitive Training Improves Verbal Memory in Adolescents and Young Adults at Clinical High Risk for Psychosis.
  Schizophrenia bulletin 2016 Loewy R, Fisher M, Schlosser DA, Biagianti B, Stuart B, Mathalon DH, Vinogradov S
• Measuring the capacity for auditory system plasticity: An examination of performance gains during initial exposure to auditory-targeted cognitive training in schizophrenia.
  Schizophrenia research 2016 Tarasenko M, Perez VB, Pianka ST, Vinogradov S, Braff DL, Swerdlow NR, Light GA
• Behavioral and emerging pharmacologic treatment options for cognitive impairment in schizophrenia.
  The Journal of clinical psychiatry 2016 Vinogradov S, Schulz SC
• Neuroscience-informed computer-assisted cognitive training in schizophrenia.
  Annals of the New York Academy of Sciences 2016 Fisher M, Herman A, Stephens DB, Vinogradov S
• Psychiatric Illnesses as Oscillatory Connectomopathies.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2016 Vinogradov S, Herman A
• Modeling the role of negative symptoms in determining social functioning in individuals at clinical high risk of psychosis.
  Schizophrenia research 2015 Schlosser DA, Campellone TR, Biagianti B, Delucchi KL, Gard DE, Fulford D, Stuart BK, Fisher M, Loewy RL, Vinogradov S
• Neural signal during immediate reward anticipation in schizophrenia: Relationship to real-world motivation and function.
  NeuroImage. Clinical 2015 Subramaniam K, Hooker CI, Biagianti B, Fisher M, Nagarajan S, Vinogradov S
• Auditory Cortical Plasticity Drives Training-Induced Cognitive Changes in Schizophrenia.
  Schizophrenia bulletin 2015 Dale CL, Brown EG, Fisher M, Herman AB, Dowling AF, Hinkley LB, Subramaniam K, Nagarajan SS, Vinogradov S
• Randomized controlled trial of computer-based treatment of social cognition in schizophrenia: the TRuSST trial protocol.
  BMC psychiatry 2015 Rose A, Vinogradov S, Fisher M, Green MF, Ventura J, Hooker C, Merzenich M, Nahum M
• The Management of Schizophrenia in Clinical Practice (MOSAIC) Registry: a focus on patients, caregivers, illness severity, functional status, disease burden and healthcare utilization.
  Schizophrenia research 2015 Nasrallah HA, Harvey PD, Casey D, Csoboth CT, Hudson JI, Julian L, Lentz E, Nuechterlein KH, Perkins DO, Kotowsky N, Skale TG, Snowden LR, Tandon R, Tek C, Velligan D, Vinogradov S, O'Gorman C
• Oxytocin administration selectively improves olfactory detection thresholds for lyral in patients with schizophrenia.
  Psychoneuroendocrinology 2015 Woolley JD, Lam O, Chuang B, Ford JM, Mathalon DH, Vinogradov S
• Do people with schizophrenia have difficulty anticipating pleasure, engaging in effortful behavior, or both?
  Journal of abnormal psychology 2014 Gard DE, Sanchez AH, Cooper K, Fisher M, Garrett C, Vinogradov S
• Symptom assessment in early psychosis: the use of well-established rating scales in clinical high-risk and recent-onset populations.
  Psychiatry research 2014 Fulford D, Pearson R, Stuart BK, Fisher M, Mathalon DH, Vinogradov S, Loewy RL
• Motivational deficits in individuals at-risk for psychosis and across the course of schizophrenia.
  Schizophrenia research 2014 Schlosser DA, Fisher M, Gard D, Fulford D, Loewy RL, Vinogradov S
• Oxytocin administration enhances controlled social cognition in patients with schizophrenia.
  Psychoneuroendocrinology 2014 Woolley JD, Chuang B, Lam O, Lai W, O'Donovan A, Rankin KP, Mathalon DH, Vinogradov S
• Intensive cognitive training in schizophrenia enhances working memory and associated prefrontal cortical efficiency in a manner that drives long-term functional gains.
  NeuroImage 2014 Subramaniam K, Luks TL, Garrett C, Chung C, Fisher M, Nagarajan S, Vinogradov S
• Using self-determination theory to understand motivation deficits in schizophrenia: the 'why' of motivated behavior.
  Schizophrenia research 2014 Gard DE, Sanchez AH, Starr J, Cooper S, Fisher M, Rowlands A, Vinogradov S
• Cognitive training in mental disorders: update and future directions.
  The American journal of psychiatry 2014 Keshavan MS, Vinogradov S, Rumsey J, Sherrill J, Wagner A
• Association between schizophrenia symptoms and neurocognition on mobility in older adults with schizophrenia.
  Aging & mental health 2014 Leutwyler H, Hubbard E, Jeste D, Miller B, Vinogradov S
• Cognitive-behavioral therapy in depressed primary care patients with co-occurring problematic alcohol use: effect of telephone-administered vs. face-to-face treatment-a secondary analysis.
  Journal of psychoactive drugs 2014 Kalapatapu RK, Ho J, Cai X, Vinogradov S, Batki SL, Mohr DC
• A novel, online social cognitive training program for young adults with schizophrenia: A pilot study.
  Schizophrenia research. Cognition 2014 Nahum M, Fisher M, Loewy R, Poelke G, Ventura J, Nuechterlein KH, Hooker CI, Green MF, Merzenich M, Vinogradov S
• Neuroplasticity-based auditory training via laptop computer improves cognition in young individuals with recent onset schizophrenia.
  Schizophrenia bulletin 2014 Fisher M, Loewy R, Carter C, Lee A, Ragland JD, Niendam T, Schlosser D, Pham L, Miskovich T, Vinogradov S
• Associations of schizophrenia symptoms and neurocognition with physical activity in older adults with schizophrenia.
  Biological research for nursing 2013 Leutwyler H, Hubbard EM, Jeste DV, Miller B, Vinogradov S
• Alcohol use biomarkers predicting cognitive performance: a secondary analysis in veterans with alcohol dependence and posttraumatic stress disorder.
  Military medicine 2013 Kalapatapu RK, Delucchi KL, Lasher BA, Vinogradov S, Batki SL
• Improving the neural mechanisms of cognition through the pursuit of happiness.
  Frontiers in human neuroscience 2013 Subramaniam K, Vinogradov S
• The influence of combined cognitive plus social-cognitive training on amygdala response during face emotion recognition in schizophrenia.
  Psychiatry research 2013 Hooker CI, Bruce L, Fisher M, Verosky SC, Miyakawa A, D'Esposito M, Vinogradov S
• Cognitive training in schizophrenia: golden age or wild west?
  Biological psychiatry 2013 Vinogradov S, Fisher M, Nagarajan S
• Symptom dimensions and functional impairment in early psychosis: more to the story than just negative symptoms.
  Schizophrenia research 2013 Fulford D, Niendam TA, Floyd EG, Carter CS, Mathalon DH, Vinogradov S, Stuart BK, Loewy RL
• Parsing the phonological loop: activation timing in the dorsal speech stream determines accuracy in speech reproduction.
  The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Herman AB, Houde JF, Vinogradov S, Nagarajan SS
• Cognitive interventions targeting brain plasticity in the prodromal and early phases of schizophrenia.
  Annual review of clinical psychology 2013 Fisher M, Loewy R, Hardy K, Schlosser D, Vinogradov S
• Cognitive training for psychiatric disorders.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2013 Subramaniam K, Vinogradov S
• Combining computerized social cognitive training with neuroplasticity-based auditory training in schizophrenia.
  Clinical schizophrenia & related psychoses 2013 Sacks S, Fisher M, Garrett C, Alexander P, Holland C, Rose D, Hooker C, Vinogradov S
• Computerized cognitive training targeting brain plasticity in schizophrenia.
  Progress in brain research 2013 Biagianti B, Vinogradov S
• Relationship of age to impulsivity and decision making: a baseline secondary analysis of a behavioral treatment study in stimulant use disorders.
  Journal of addictive diseases 2013 Kalapatapu RK, Lewis DF, Vinogradov S, Batki SL, Winhusen T
• Videogames to Promote Physical Activity in Older Adults with Schizophrenia.
  Games for health journal 2012 Leutwyler H, Hubbard EM, Vinogradov S, Dowling GA
• "We're not just sitting on the periphery": a staff perspective of physical activity in older adults with schizophrenia.
  The Gerontologist 2012 Leutwyler H, Hubbard EM, Jeste DV, Vinogradov S
• Genetic correlate of cognitive training response in schizophrenia.
  Neuropharmacology 2012 Panizzutti R, Hamilton SP, Vinogradov S
• Neural activity during emotion recognition after combined cognitive plus social cognitive training in schizophrenia.
  Schizophrenia research 2012 Hooker CI, Bruce L, Fisher M, Verosky SC, Miyakawa A, Vinogradov S
• Low maternal hemoglobin during pregnancy and diminished neuromotor and neurocognitive performance in offspring with schizophrenia.
  Schizophrenia research 2012 Ellman LM, Vinogradov S, Kremen WS, Poole JH, Kern DM, Deicken RF, Brown AS
• Feasibility and pilot efficacy results from the multisite Cognitive Remediation in the Schizophrenia Trials Network (CRSTN) randomized controlled trial.
  The Journal of clinical psychiatry 2012 Keefe RS, Vinogradov S, Medalia A, Buckley PF, Caroff SN, D'Souza DC, Harvey PD, Graham KA, Hamer RM, Marder SM, Miller DD, Olson SJ, Patel JK, Velligan D, Walker TM, Haim AJ, Stroup TS
• Birth weight and neurocognition in schizophrenia spectrum disorders.
  Schizophrenia bulletin 2012 Freedman D, Bao Y, Kremen WS, Vinogradov S, McKeague IW, Brown AS
• Computerized cognitive training restores neural activity within the reality monitoring network in schizophrenia.
  Neuron 2012 Subramaniam K, Luks TL, Fisher M, Simpson GV, Nagarajan S, Vinogradov S
• Error monitoring dysfunction across the illness course of schizophrenia.
  Journal of abnormal psychology 2011 Perez VB, Ford JM, Roach BJ, Woods SW, McGlashan TH, Srihari VH, Loewy RL, Vinogradov S, Mathalon DH
• Cognitive training for impaired neural systems in neuropsychiatric illness.
  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011 Vinogradov S, Fisher M, de Villers-Sidani E
• Auditory cortex responsiveness during talking and listening: early illness schizophrenia and patients at clinical high-risk for psychosis.
  Schizophrenia bulletin 2011 Perez VB, Ford JM, Roach BJ, Loewy RL, Stuart BK, Vinogradov S, Mathalon DH
• Copy number variants for schizophrenia and related psychotic disorders in Oceanic Palau: risk and transmission in extended pedigrees.
  Biological psychiatry 2011 Melhem N, Middleton F, McFadden K, Klei L, Faraone SV, Vinogradov S, Tiobech J, Yano V, Kuartei S, Roeder K, Byerley W, Devlin B, Myles-Worsley M
• Theory of mind skills are related to gray matter volume in the ventromedial prefrontal cortex in schizophrenia.
  Biological psychiatry 2011 Hooker CI, Bruce L, Lincoln SH, Fisher M, Vinogradov S
• Clinical symptoms and alpha band resting-state functional connectivity imaging in patients with schizophrenia: implications for novel approaches to treatment.
  Biological psychiatry 2011 Hinkley LB, Vinogradov S, Guggisberg AG, Fisher M, Findlay AM, Nagarajan SS
• Association of maternal genital and reproductive infections with verbal memory and motor deficits in adult schizophrenia.
  Psychiatry research 2011 Brown AS, Vinogradov S, Kremen WS, Poole JH, Bao Y, Kern D, McKeague IW
• Maternal-fetal blood incompatibility and neuromorphologic anomalies in schizophrenia: Preliminary findings.
  Progress in neuro-psychopharmacology & biological psychiatry 2011 Freedman D, Deicken R, Kegeles LS, Vinogradov S, Bao Y, Brown AS
• Psychosis risk screening with the Prodromal Questionnaire--brief version (PQ-B).
  Schizophrenia research 2011 Loewy RL, Pearson R, Vinogradov S, Bearden CE, Cannon TD
• Harnessing neuroplasticity for clinical applications.
  Brain : a journal of neurology 2011 Cramer SC, Sur M, Dobkin BH, O'Brien C, Sanger TD, Trojanowski JQ, Rumsey JM, Hicks R, Cameron J, Chen D, Chen WG, Cohen LG, deCharms C, Duffy CJ, Eden GF, Fetz EE, Filart R, Freund M, Grant SJ, Haber…
• Familial transmission of schizophrenia in Palau: A 20-year genetic epidemiological study in three generations.
  American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011 Myles-Worsley M, Tiobech J, Blailes F, Middleton FA, Vinogradov S, Byerley W, Faraone SV
• Can I trust you? Negative affective priming influences social judgments in schizophrenia.
  Journal of abnormal psychology 2011 Hooker CI, Tully LM, Verosky SC, Fisher M, Holland C, Vinogradov S
• Evidence for an emotion maintenance deficit in schizophrenia.
  Psychiatry research 2011 Gard DE, Cooper S, Fisher M, Genevsky A, Mikels JA, Vinogradov S
• Cognitive Impairments in Schizophrenia as Assessed Through Activation and Connectivity Measures of Magnetoencephalography (MEG) Data.
  Frontiers in human neuroscience 2010 Hinkley LB, Owen JP, Fisher M, Findlay AM, Vinogradov S, Nagarajan SS
• Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8.
  Schizophrenia research 2010 Ellman LM, Deicken RF, Vinogradov S, Kremen WS, Poole JH, Kern DM, Tsai WY, Schaefer CA, Brown AS
• Report from the working group conference on multisite trial design for cognitive remediation in schizophrenia.
  Schizophrenia bulletin 2010 Keefe RS, Vinogradov S, Medalia A, Silverstein SM, Bell MD, Dickinson D, Ventura J, Marder SR, Stroup TS
• Predicting the longitudinal effects of the family environment on prodromal symptoms and functioning in patients at-risk for psychosis.
  Schizophrenia research 2010 Schlosser DA, Zinberg JL, Loewy RL, Casey-Cannon S, O'Brien MP, Bearden CE, Vinogradov S, Cannon TD
• Cognitive decline in schizophrenia from childhood to midlife: a 33-year longitudinal birth cohort study.
  Schizophrenia research 2010 Kremen WS, Vinogradov S, Poole JH, Schaefer CA, Deicken RF, Factor-Litvak P, Brown AS
• Cognitive training in schizophrenia: a neuroscience-based approach.
  Dialogues in clinical neuroscience 2010 Genevsky A, Garrett CT, Alexander PP, Vinogradov S
• Timing is everything: neural response dynamics during syllable processing and its relation to higher-order cognition in schizophrenia and healthy comparison subjects.
  International journal of psychophysiology : official journal of the International Organization of Psychophysiology 2009 Dale CL, Findlay AM, Adcock RA, Vertinski M, Fisher M, Genevsky A, Aldebot S, Subramaniam K, Luks TL, Simpson GV, Nagarajan SS, Vinogradov S
• Motivation and its relationship to neurocognition, social cognition, and functional outcome in schizophrenia.
  Schizophrenia research 2009 Gard DE, Fisher M, Garrett C, Genevsky A, Vinogradov S
• When top-down meets bottom-up: auditory training enhances verbal memory in schizophrenia.
  Schizophrenia bulletin 2009 Adcock RA, Dale C, Fisher M, Aldebot S, Genevsky A, Simpson GV, Nagarajan S, Vinogradov S
• The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia.
  The American journal of psychiatry 2009 Vinogradov S, Fisher M, Warm H, Holland C, Kirshner MA, Pollock BG
• Using neuroplasticity-based auditory training to improve verbal memory in schizophrenia.
  The American journal of psychiatry 2009 Fisher M, Holland C, Merzenich MM, Vinogradov S
• Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia?
  Biological psychiatry 2009 Vinogradov S, Fisher M, Holland C, Shelly W, Wolkowitz O, Mellon SH
• Prenatal exposure to maternal infection and executive dysfunction in adult schizophrenia.
  The American journal of psychiatry 2009 Brown AS, Vinogradov S, Kremen WS, Poole JH, Deicken RF, Penner JD, McKeague IW, Kochetkova A, Kern D, Schaefer CA
• Neuroplasticity-based cognitive training in schizophrenia: an interim report on the effects 6 months later.
  Schizophrenia bulletin 2009 Fisher M, Holland C, Subramaniam K, Vinogradov S
• Prenatal infection and cavum septum pellucidum in adult schizophrenia.
  Schizophrenia research 2009 Brown AS, Deicken RF, Vinogradov S, Kremen WS, Poole JH, Penner JD, Kochetkova A, Kern D, Schaefer CA
• Self and other in schizophrenia: a cognitive neuroscience perspective.
  The American journal of psychiatry 2008 Fisher M, McCoy K, Poole JH, Vinogradov S
• Automatic relevance determination for identifying thalamic regions implicated in schizophrenia.
  IEEE transactions on neural networks 2008 Browne A, Jakary A, Vinogradov S, Fu Y, Deicken RF
• Deficit in a neural correlate of reality monitoring in schizophrenia patients.
  Cerebral cortex (New York, N.Y. : 1991) 2008 Vinogradov S, Luks TL, Schulman BJ, Simpson GV
• No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics.
  The American journal of psychiatry 2008 Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, Burrell GJ, Rice JP, Nertney DA, Olincy A, Rozic P, Vinogradov S, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, …
• A neurocognitive model of borderline personality disorder: effects of childhood sexual abuse and relationship to adult social attachment disturbance.
  Development and psychopathology 2008 Minzenberg MJ, Poole JH, Vinogradov S
• Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophrenia.
  Schizophrenia bulletin 2007 Kumra S, Oberstar JV, Sikich L, Findling RL, McClellan JM, Vinogradov S, Charles Schulz S
• Social-emotion recognition in borderline personality disorder.
  Comprehensive psychiatry 2006 Minzenberg MJ, Poole JH, Vinogradov S
• Adult social attachment disturbance is related to childhood maltreatment and current symptoms in borderline personality disorder.
  The Journal of nervous and mental disease 2006 Minzenberg MJ, Poole JH, Vinogradov S
• Brain activation patterns during memory of cognitive agency.
  NeuroImage 2006 Vinogradov S, Luks TL, Simpson GV, Schulman BJ, Glenn S, Wong AE
• Reduced Self-Referential Source Memory Performance is Associated with Interpersonal Dysfunction in Borderline Personality Disorder.
  Journal of personality disorders 2006 Minzenberg MJ, Fisher-Irving M, Poole JH, Vinogradov S
• N-acetylaspartate reductions in the mediodorsal and anterior thalamus in men with schizophrenia verified by tissue volume corrected proton MRSI.
  Schizophrenia research 2005 Jakary A, Vinogradov S, Feiwell R, Deicken RF
• Association of anticholinergic load with impairment of complex attention and memory in schizophrenia.
  The American journal of psychiatry 2004 Minzenberg MJ, Poole JH, Benton C, Vinogradov S
• Slowed lexical access is uniquely associated with positive and disorganised symptoms in schizophrenia.
  Cognitive neuropsychiatry 2003 Minzenberg MJ, Poole JH, Vinogradov S, Shenaut GK, Ober BA
• Anterior hippocampal volume reduction in male patients with schizophrenia.
  Schizophrenia research 2003 Pegues MP, Rogers LJ, Amend D, Vinogradov S, Deicken RF
• Comorbidity of bipolar disorder and substance abuse in Costa Rica: pedigree- and population-based studies.
  Journal of affective disorders 2002 Escamilla MA, Batki S, Reus VI, Spesny M, Molina J, Service S, Vinogradov S, Neylan T, Mathews C, Meza L, Gallegos A, Montero AP, Cruz ML, Neuhaus J, Roche E, Smith L, Leon P, Freimer NB
• Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study.
  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2002 Marco EJ, Wolkowitz OM, Vinogradov S, Poole JH, Lichtmacher J, Reus VI
• Semantic priming in schizophrenia: a review and synthesis.
  Journal of the International Neuropsychological Society : JINS 2002 Minzenberg MJ, Ober BA, Vinogradov S
• Genome screening for linkage disequilibrium in a Costa Rican sample of patients with bipolar-I disorder: a follow-up study on chromosome 18.
  American journal of medical genetics 2001 Escamilla MA, McInnes LA, Service SK, Spesny M, Reus VI, Molina J, Gallegos A, Fournier E, Batki S, Neylan T, Matthews C, Vinogradov S, Roche E, Tyler DJ, Shimayoshi N, Mendez R, Ramirez R, Ramirez M,…
• The functional relevance of affect recognition errors in schizophrenia.
  Journal of the International Neuropsychological Society : JINS 2000 Poole JH, Tobias FC, Vinogradov S
• Assessing the feasibility of linkage disequilibrium methods for mapping complex traits: an initial screen for bipolar disorder loci on chromosome 18.
  American journal of human genetics 1999 Escamilla MA, McInnes LA, Spesny M, Reus VI, Service SK, Shimayoshi N, Tyler DJ, Silva S, Molina J, Gallegos A, Meza L, Cruz ML, Batki S, Vinogradov S, Neylan T, Nguyen JB, Fournier E, Araya C, …
• Independent frontal-system deficits in schizophrenia: cognitive, clinical, and adaptive implications.
  Psychiatry research 1999 Poole JH, Ober BA, Shenaut GK, Vinogradov S
• Slower and more variable reaction times in schizophrenia: what do they signify?
  Schizophrenia research 1998 Vinogradov S, Poole JH, Willis-Shore J, Ober BA, Shenaut GK
• Clinical and neurocognitive aspects of source monitoring errors in schizophrenia.
  The American journal of psychiatry 1997 Vinogradov S, Willis-Shore J, Poole JH, Marten E, Ober BA, Shenaut GK
• Decreased left frontal lobe N-acetylaspartate in schizophrenia.
  The American journal of psychiatry 1997 Deicken RF, Zhou L, Corwin F, Vinogradov S, Weiner MW
• A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees.
  Proceedings of the National Academy of Sciences of the United States of America 1996 McInnes LA, Escamilla MA, Service SK, Reus VI, Leon P, Silva S, Rojas E, Spesny M, Baharloo S, Blankenship K, Peterson A, Tyler D, Shimayoshi N, Tobey C, Batki S, Vinogradov S, Meza L, Gallegos A, …
• An approach to investigating linkage for bipolar disorder using large Costa Rican pedigrees.
  American journal of medical genetics 1996 Freimer NB, Reus VI, Escamilla M, Spesny M, Smith L, Service S, Gallegos A, Meza L, Batki S, Vinogradov S, Leon P, Sandkuijl LA
• Do semantic priming effects correlate with sensory gating in schizophrenia?
  Biological psychiatry 1996 Vinogradov S, Solomon S, Ober BA, Biggins CA, Shenaut GK, Fein G
• Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23.
  Nature genetics 1996 Freimer NB, Reus VI, Escamilla MA, McInnes LA, Spesny M, Leon P, Service SK, Smith LB, Silva S, Rojas E, Gallegos A, Meza L, Fournier E, Baharloo S, Blankenship K, Tyler DJ, Batki S, Vinogradov S, …
• Asymmetry of temporal lobe phosphorous metabolism in schizophrenia: a 31phosphorous magnetic resonance spectroscopic imaging study.
  Biological psychiatry 1995 Deicken RF, Calabrese G, Merrin EL, Vinogradov S, Fein G, Weiner MW
• Semantic priming of word pronunciation and lexical decision in schizophrenia.
  Schizophrenia research 1992 Vinogradov S, Ober BA, Shenaut GK
• An associationist model of the paranoid process: application of phase transitions in spreading activation networks.
  Psychiatry 1992 Vinogradov S, King RJ, Huberman BA
• Negative association between schizophrenia and rheumatoid arthritis.
  Schizophrenia bulletin 1991 Vinogradov S, Gottesman II, Moises HW, Nicol S
• Postpartum psychosis with abnormal movements: dopamine supersensitivity unmasked by withdrawal of endogenous estrogens?
  The Journal of clinical psychiatry 1990 Vinogradov S, Csernansky JG