Soonmee Cha, MD
Professor
Radiology
School of Medicine

She obtained her medical degree from Georgetown University, School of Medicine, Washington in 1991. She completed her Diagnostic Radiology residency from North Shore University Hospital, Cornell University Medical College in New York, followed by a fellowship in Neuroradiology from New York University Medical Center in 1998.

Dr. Cha is committed to a career dedicated to patient-oriented research in the field of brain tumor imaging. She believes that non-invasive imaging technology will make important contributions to the health of patients through improving the specificity and precision of diagnosis and treatment monitoring, which will have significant impact on therapeutic decisions.

The main focus of Dr. Cha’s research is to identify reliable surrogate markers of prognosis and therapeutic efficacy by quantitative MR imaging methods in patients with brain tumors. She believes that by using MR imaging techniques such perfusion MR imaging, diffusion-weighted imaging, and 3-dimensional proton magnetic resonance spectroscopic imaging, detection of changes in tumor angiogenesis, cellularity, invasion, tumor hypoxia, and metabolic burden can be accurately measured and will provide more specific information about patient’s early response to therapy in the context of tumor growth.

Dr. Cha has been awarded several NIH grants, serving as Principal Investigator and Co-Principal Investigator on many NIH projects. She has published 87 articles, and she has written 77 peer-reviewed articles and 4 book chapters.

Expertise: Neuroradiology

Specialty: Brain tumor imaging

Professional Interests: Brain tumor, brain cancer, glioblastoma multiforme, gliomas, primary cerebral lymphoma, angiogenesis, hypoxia, invasion, perfusion MR imaging, diffusion-weighted imaging, molecular imaging, biomarkers, microarray, genomics, neural stem cell

Education and Training:

• Medical School: Georgetown University, College of Arts and Sciences, Washington, District of Columbia
• Internship: Georgetown University Fairfax Hospital, Falls Church
• Residency: North Shore University Hospital, Cornell University Medical College, Manhasset, New York - Diagnostic Radiology
• Fellowship: New York University Medical Center, New York - Neuroradiology

• Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.
  Neuro-oncology 2022 Zhang Y, Lucas CG, Young JS, Morshed RA, McCoy L, Oberheim Bush NA, Taylor JW, Daras M, Butowski NA, Villanueva-Meyer JE, Cha S, Wrensch M, Wiencke JK, Lee JC, Pekmezci M, Phillips JJ, Perry A, Bollen…
• Longitudinal Assessment of Posttreatment Diffuse Glioma Tissue Volumes with Three-dimensional Convolutional Neural Networks.
  Radiology. Artificial intelligence 2022 Rudie JD, Calabrese E, Saluja R, Weiss D, Colby JB, Cha S, Hess CP, Rauschecker AM, Sugrue LP, Villanueva-Meyer JE
• Combining radiomics and deep convolutional neural network features from preoperative MRI for predicting clinically relevant genetic biomarkers in glioblastoma.
  Neuro-oncology advances 2022 Calabrese E, Rudie JD, Rauschecker AM, Villanueva-Meyer JE, Clarke JL, Solomon DA, Cha S
• Advanced Imaging Techniques for Newly Diagnosed and Recurrent Gliomas.
  Frontiers in neuroscience 2022 Carrete LR, Young JS, Cha S
• Susceptibility-Weighted Imaging of Intravascular Lymphoma of the Central Nervous System.
  JAMA neurology 2022 Richie MB, Guterman EL, Shah MP, Cha S
• EWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma.
  Acta neuropathologica 2021 Lucas CG, Gupta R, Wu J, Shah K, Ravindranathan A, Barreto J, Gener M, Ginn KF, Prall OWJ, Xu H, Kee D, Ko HS, Yaqoob N, Zia N, Florez A, Cha S, Perry A, Clarke JL, Chang SM, Berger MS, Solomon DA
• Functional outcomes after resection of middle frontal gyrus diffuse gliomas.
  Journal of neurosurgery 2021 Morshed RA, Lee AT, Wang EJ, Young JS, Cha S, Hervey-Jumper SL, Berger MS
• Systemic and Craniospinal Rosai Dorfman Disease with Intraparenchymal, Intramedullary and Leptomeningeal Disease.
  International journal of hematology-oncology and stem cell research 2021 Li Y, Sloan E, Bollen A, Solomon D, Theodosopoulos P, Cha S
• Relationship between incidence of postoperative radial nerve palsy and surgical experience in the treatment of humeral shaft fractures through a posterior triceps splitting approach: A retrospective study.
  Acta orthopaedica et traumatologica turcica 2021 Lee WY, Shin HD, Kim KC, Cha SM, Jeon YS
• Feasibility of Simulated Postcontrast MRI of Glioblastomas and Lower-Grade Gliomas by Using Three-dimensional Fully Convolutional Neural Networks.
  Radiology. Artificial intelligence 2021 Calabrese E, Rudie JD, Rauschecker AM, Villanueva-Meyer JE, Cha S
• Open Reduction and Stable Internal Fixation Using a 3.5-mm Locking Hook Plate for Isolated Fractures of the Greater Tuberosity of the Humerus: A 2-Year Follow-up Study Using an Innovative Fixation Method.
  Clinics in orthopedic surgery 2021 Lee WY, Shin HD, Kim KC, Cha SM, Jeon YS, Kim DH
• Recurrent tumor and treatment-induced effects have different MR signatures in contrast enhancing and non-enhancing lesions of high-grade gliomas.
  Neuro-oncology 2020 Cluceru J, Nelson SJ, Wen Q, Phillips JJ, Shai A, Molinaro AM, Alcaide-Leon P, Olson MP, Nair D, LaFontaine M, Chunduru P, Villanueva-Meyer JE, Cha S, Chang SM, Berger MS, Lupo JM
• Autogenous Bone Graft With Kirschner Wire Fixation Could Be a Reliable Treatment Option for Scaphoid Nonunion in Adolescents.
  Journal of pediatric orthopedics 2020 Choi ES, Cha SM, Shin HD
• A fully automated artificial intelligence method for non-invasive, imaging-based identification of genetic alterations in glioblastomas.
  Scientific reports 2020 Calabrese E, Villanueva-Meyer JE, Cha S
• Features of the Ulnar Nerve Predicting Postoperative Prognosis in Idiopathic Cubital Tunnel Syndrome: Three Distinct Features of the Ulnar Nerve.
  Annals of plastic surgery 2020 Cha SM, Shin HD
• Long-term outcomes of distal humeral epiphyseal separations treated via closed reduction and pinning under arthrogram.
  Injury 2019 Cha SM, Shin HD, Choi ES
• Disruption of Frontal Aslant Tract Is Not Associated with Long-Term Postoperative Language Deficits.
  World neurosurgery 2019 Young JS, Morshed RA, Mansoori Z, Cha S, Berger MS
• Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas.
  Acta neuropathologica 2019 Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, …
• High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis.
  Brain pathology (Zurich, Switzerland) 2019 Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, …
• Histological Evidence of Intrinsic Muscle Degeneration in Compression Ulnar Neuropathy.
  Annals of plastic surgery 2019 Cha SM, Shin HD, Kim KH, Kim JH
• Cross-sectional Area Just Proximal to the Carpal Tunnel According to the Ulnar Variances: Positive Ulnar Variance and Carpal Tunnel Syndrome.
  Annals of plastic surgery 2019 Cha SM, Shin HD, Song SH
• Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR.
  JCI insight 2018 Behr SC, Villanueva-Meyer JE, Li Y, Wang YH, Wei J, Moroz A, Lee JK, Hsiao JC, Gao KT, Ma W, Cha S, Wilson DM, Seo Y, Nelson SJ, Chang SM, Evans MJ
• Phase III study of cisplatin with or without S-1 in patients with stage IVB, recurrent, or persistent cervical cancer.
  British journal of cancer 2018 Aoki Y, Ochiai K, Lim S, Aoki D, Kamiura S, Lin H, Katsumata N, Cha SD, Kim JH, Kim BG, Hirashima Y, Fujiwara K, Kim YT, Kim SM, Chung HH, Chang TC, Kamura T, Takizawa K, Takeuchi M, Kang SB
• Tailoring Radiology Resident Education Using Aggregated Missed-Cases Data.
  Journal of the American College of Radiology : JACR 2018 Merritt BA, Henry TS, Cha S, Ordovas KG, Kallianos KG, Elicker BM, Hope MD, Naeger DM
• Early detection of recurrent medulloblastoma: the critical role of diffusion-weighted imaging.
  Neuro-oncology practice 2018 Aboian MS, Kline CN, Li Y, Solomon DA, Felton E, Banerjee A, Braunstein SE, Mueller S, Dillon WP, Cha S
• MRI Features and IDH Mutational Status of Grade II Diffuse Gliomas: Impact on Diagnosis and Prognosis.
  AJR. American journal of roentgenology 2017 Villanueva-Meyer JE, Wood MD, Choi BS, Mabray MC, Butowski NA, Tihan T, Cha S
• Characterization of Metabolic, Diffusion, and Perfusion Properties in GBM: Contrast-Enhancing versus Non-Enhancing Tumor.
  Translational oncology 2017 Autry A, Phillips JJ, Maleschlijski S, Roy R, Molinaro AM, Chang SM, Cha S, Lupo JM, Nelson SJ
• Current Clinical Brain Tumor Imaging.
  Neurosurgery 2017 Villanueva-Meyer JE, Mabray MC, Cha S
• Case-based review: pediatric medulloblastoma.
  Neuro-oncology practice 2017 Kline CN, Packer RJ, Hwang EI, Raleigh DR, Braunstein S, Raffel C, Bandopadhayay P, Solomon DA, Aboian M, Cha S, Mueller S
• Clinical and imaging correlation in patients with pathologically confirmed tumefactive demyelinating lesions.
  Journal of the neurological sciences 2017 Tremblay MA, Villanueva-Meyer JE, Cha S, Tihan T, Gelfand JM
• Radiological degenerative changes in the distal radioulnar joint after ulnar shortening osteotomy in patients with idiopathic ulnar impaction syndrome: Analysis of factors affecting degenerative lesions.
  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2017 Cha SM, Choi BS, Shin HD
• Early tumor growth between initial resection and radiotherapy of glioblastoma: incidence and impact on clinical outcomes.
  Journal of neuro-oncology 2017 Villanueva-Meyer JE, Han SJ, Cha S, Butowski NA
• Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.
  Neuro-oncology 2017 Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, …
• Bevacizumab in Recurrent Glioma: Patterns of Treatment Failure and Implications.
  Brain tumor research and treatment 2017 Li Y, Ali S, Clarke J, Cha S
• Prognostic Factors Affecting Union After Ulnar Shortening Osteotomy in Ulnar Impaction Syndrome: A Retrospective Case-Control Study.
  The Journal of bone and joint surgery. American volume 2017 Cha SM, Shin HD, Ahn KJ
• PET/MRI: Where might it replace PET/CT?
  Journal of magnetic resonance imaging : JMRI 2017 Ehman EC, Johnson GB, Villanueva-Meyer JE, Cha S, Leynes AP, Larson PEZ, Hope TA
• Association of early changes in 1H MRSI parameters with survival for patients with newly diagnosed glioblastoma receiving a multimodality treatment regimen.
  Neuro-oncology 2017 Nelson SJ, Kadambi AK, Park I, Li Y, Crane J, Olson M, Molinaro A, Roy R, Butowski N, Cha S, Chang S
• Hsp90 inhibitor SY-016 induces G2/M arrest and apoptosis in paclitaxel-resistant human ovarian cancer cells.
  Oncology letters 2017 Lee HG, Park WJ, Shin SJ, Kwon SH, Cha SD, Seo YH, Jeong JH, Lee JY, Cho CH
• Quantitative multi-modal MR imaging as a non-invasive prognostic tool for patients with recurrent low-grade glioma.
  Journal of neuro-oncology 2017 Neill E, Luks T, Dayal M, Phillips JJ, Perry A, Jalbert LE, Cha S, Molinaro A, Chang SM, Nelson SJ
• Glioma FMISO PET/MR Imaging Concurrent with Antiangiogenic Therapy: Molecular Imaging as a Clinical Tool in the Burgeoning Era of Personalized Medicine.
  Biomedicines 2016 Barajas RF, Krohn KA, Link JM, Hawkins RA, Clarke JL, Pampaloni MH, Cha S
• Advanced MR Imaging Techniques in Daily Practice.
  Neuroimaging clinics of North America 2016 Mabray MC, Cha S
• Metastasis in Adult Brain Tumors.
  Neuroimaging clinics of North America 2016 Barajas RF, Cha S
• Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
  Journal of neuro-oncology 2016 Nelson SJ, Li Y, Lupo JM, Olson M, Crane JC, Molinaro A, Roy R, Clarke J, Butowski N, Prados M, Cha S, Chang SM
• The Development of Reduced Diffusion Following Bevacizumab Therapy Identifies Regions of Recurrent Disease in Patients with High-grade Glioma.
  Academic radiology 2016 Barajas RF, Butowski NA, Phillips JJ, Aghi MK, Berger MS, Chang SM, Cha S
• Relationship of cubitus varus and ulnar varus deformity in supracondylar humeral fractures according to the age at injury.
  Journal of shoulder and elbow surgery 2016 Cha SM, Shin HD, Ahn JS
• Differences in the Postoperative Outcomes According to the Primary Treatment Options Chosen by Patients With Carpal Tunnel Syndrome: Conservative Versus Operative Treatment.
  Annals of plastic surgery 2016 Cha SM, Shin HD, Ahn JS, Beom JW, Kim DY
• CNS angiitis as a brain tumor mimic with a branching vascular abnormality on T2* MRI.
  Neurology 2015 Mabray MC, Cha S
• Performance of Apparent Diffusion Coefficient Values and Conventional MRI Features in Differentiating Tumefactive Demyelinating Lesions From Primary Brain Neoplasms.
  AJR. American journal of roentgenology 2015 Mabray MC, Cohen BA, Villanueva-Meyer JE, Valles FE, Barajas RF, Rubenstein JL, Cha S
• Adult-onset central nervous system hemophagocytic lymphohistiocytosis: a case report.
  BMC neurology 2015 Pastula DM, Burish M, Reis GF, Bollen A, Cha S, Ralph J, Douglas VC
• Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials.
  Neuro-oncology 2015 Ellingson BM, Bendszus M, Boxerman J, Barboriak D, Erickson BJ, Smits M, Nelson SJ, Gerstner E, Alexander B, Goldmacher G, Wick W, Vogelbaum M, Weller M, Galanis E, Kalpathy-Cramer J, Shankar L, …
• From Shades of Gray to Microbiologic Imaging: A Historical Review of Brain Abscess Imaging: RSNA Centennial Article.
  Radiographics : a review publication of the Radiological Society of North America, Inc 2015 Villanueva-Meyer JE, Cha S
• The effects of anti-angiogenic therapy on the formation of radiation-induced microbleeds in normal brain tissue of patients with glioma.
  Neuro-oncology 2015 Lupo JM, Molinaro AM, Essock-Burns E, Butowski N, Chang SM, Cha S, Nelson SJ
• Surgical Management of Intracranial Neuroenteric Cysts: The UCSF Experience.
  Journal of neurological surgery. Part B, Skull base 2015 Breshears JD, Rutkowski MJ, McDermott MW, Cha S, Tihan T, Theodosopoulos PV
• Temporary scaphocapitate fixation with or without radial shortening for adolescent Kienböck's disease.
  Journal of pediatric orthopedics. Part B 2015 Cha SM, Shin HD, Ahn JS, Noh CK
• Modern brain tumor imaging.
  Brain tumor research and treatment 2015 Mabray MC, Barajas RF, Cha S
• Reduced apparent diffusion coefficient in neuromyelitis optica-associated optic neuropathy.
  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 2015 Horton JC, Douglas VC, Cha S
• Assessing Biological Response to Bevacizumab Using 18F-Fluoromisonidazole PET/MR Imaging in a Patient with Recurrent Anaplastic Astrocytoma.
  Case reports in radiology 2015 Barajas RF, Pampaloni MH, Clarke JL, Seo Y, Savic D, Hawkins RA, Behr SC, Chang SM, Berger M, Dillon WP, Cha S
• Benefits of dynamic susceptibility-weighted contrast-enhanced perfusion MRI for glioma diagnosis and therapy.
  CNS oncology 2014 Barajas RF, Cha S
• Apparent diffusion coefficient in glioblastoma with PNET-like components, a GBM variant.
  Journal of neuro-oncology 2014 Ali S, Joseph NM, Perry A, Barajas RF, Cha S
• Comparisons of retear patterns for 3 arthroscopic rotator cuff repair methods.
  The American journal of sports medicine 2014 Kim KC, Shin HD, Cha SM, Park JY
• Outcomes of the mini-open Outerbridge-Kashiwagi procedure according to preoperative radiocapitellar joint status.
  The Journal of hand surgery 2013 Cha SM, Shin HD, Kim KC, Park IY
• Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
  Science (New York, N.Y.) 2013 Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, Fouse SD, Yamamoto S, Ueda H, Tatsuno K, Asthana S, Jalbert LE, Nelson SJ, Bollen AW, Gustafson WC, Charron E, Weiss WA, Smirnov IV, Song JS…
• Individualized prediction of overall survival after postoperative radiation therapy in patients with early-stage cervical cancer: a Korean Radiation Oncology Group study (KROG 13-03).
  International journal of radiation oncology, biology, physics 2013 Lee HJ, Han S, Kim YS, Nam JH, Kim HJ, Kim JW, Park W, Kim BG, Kim JH, Cha SD, Kim J, Lee KH, Yoon MS, Kim SM, Kim JY, Yoon WS, Lee NW, Choi JH, Park SY, Kim JY
• Complement activation and intraventricular rituximab distribution in recurrent central nervous system lymphoma.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Kadoch C, Li J, Wong VS, Chen L, Cha S, Munster P, Lowell CA, Shuman MA, Rubenstein JL
• Plating after tibial lengthening: unilateral monoaxial external fixator and locking plate.
  Journal of pediatric orthopedics. Part B 2013 Cha SM, Shin HD, Kim KC, Song JH
• CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma.
  Blood 2013 Rubenstein JL, Wong VS, Kadoch C, Gao HX, Barajas R, Chen L, Josephson SA, Scott B, Douglas V, Maiti M, Kaplan LD, Treseler PA, Cha S, Hwang JH, Cinque P, Cyster JG, Lowell C
• Survival analysis in patients with newly diagnosed glioblastoma using pre- and postradiotherapy MR spectroscopic imaging.
  Neuro-oncology 2013 Li Y, Lupo JM, Parvataneni R, Lamborn KR, Cha S, Chang SM, Nelson SJ
• Using susceptibility-weighted imaging to determine response to combined anti-angiogenic, cytotoxic, and radiation therapy in patients with glioblastoma multiforme.
  Neuro-oncology 2013 Lupo JM, Essock-Burns E, Molinaro AM, Cha S, Chang SM, Butowski N, Nelson SJ
• Comparison of DSC-MRI post-processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM.
  Journal of magnetic resonance imaging : JMRI 2012 Essock-Burns E, Phillips JJ, Molinaro AM, Lupo JM, Cha S, Chang SM, Nelson SJ
• Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma.
  Blood 2012 Rubenstein JL, Li J, Chen L, Advani R, Drappatz J, Gerstner E, Batchelor T, Krouwer H, Hwang J, Auerback G, Kadoch C, Lowell C, Munster P, Cha S, Shuman MA, Damon LE
• Relationship of glioblastoma multiforme to the subventricular zone is associated with survival.
  Neuro-oncology 2012 Jafri NF, Clarke JL, Weinberg V, Barani IJ, Cha S
• Impact of extent of resection for recurrent glioblastoma on overall survival: clinical article.
  Journal of neurosurgery 2012 Bloch O, Han SJ, Cha S, Sun MZ, Aghi MK, McDermott MW, Berger MS, Parsa AT
• Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging.
  Neuro-oncology 2012 Barajas RF, Phillips JJ, Parvataneni R, Molinaro A, Essock-Burns E, Bourne G, Parsa AT, Aghi MK, McDermott MW, Berger MS, Cha S, Chang SM, Nelson SJ
• Spatial characteristics of newly diagnosed grade 3 glioma assessed by magnetic resonance metabolic and diffusion tensor imaging.
  Translational oncology 2012 Ozturk-Isik E, Pirzkall A, Lamborn KR, Cha S, Chang SM, Nelson SJ
• Magnetic resonance of 2-hydroxyglutarate in IDH1-mutated low-grade gliomas.
  Science translational medicine 2012 Elkhaled A, Jalbert LE, Phillips JJ, Yoshihara HAI, Parvataneni R, Srinivasan R, Bourne G, Berger MS, Chang SM, Cha S, Nelson SJ
• Imaging diagnosis of brain metastasis.
  Progress in neurological surgery 2012 Barajas RF, Cha S
• Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.
  Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Wieduwilt MJ, Valles F, Issa S, Behler CM, Hwang J, McDermott M, Treseler P, O'Brien J, Shuman MA, Cha S, Damon LE, Rubenstein JL
• Intracranial subdural osteoma: a rare benign tumor that can be differentiated from other calcified intracranial lesions utilizing MR imaging.
  Journal of neuroradiology = Journal de neuroradiologie 2011 Barajas RF, Perry A, Sughrue M, Aghi M, Cha S
• MRI apparent diffusion coefficient reflects histopathologic subtype, axonal disruption, and tumor fraction in diffuse-type grade II gliomas.
  Neuro-oncology 2011 Khayal IS, Vandenberg SR, Smith KJ, Cloyd CP, Chang SM, Cha S, Nelson SJ, McKnight TR
• Serial analysis of imaging parameters in patients with newly diagnosed glioblastoma multiforme.
  Neuro-oncology 2011 Li Y, Lupo JM, Polley MY, Crane JC, Bian W, Cha S, Chang S, Nelson SJ
• Assessment of perfusion MRI-derived parameters in evaluating and predicting response to antiangiogenic therapy in patients with newly diagnosed glioblastoma.
  Neuro-oncology 2010 Essock-Burns E, Lupo JM, Cha S, Polley MY, Butowski NA, Chang SM, Nelson SJ
• Ex vivo MR spectroscopic measure differentiates tumor from treatment effects in GBM.
  Neuro-oncology 2010 Srinivasan R, Phillips JJ, Vandenberg SR, Polley MY, Bourne G, Au A, Pirzkall A, Cha S, Chang SM, Nelson SJ
• Evaluation of diffusion parameters as early biomarkers of disease progression in glioblastoma multiforme.
  Neuro-oncology 2010 Khayal IS, Polley MY, Jalbert L, Elkhaled A, Chang SM, Cha S, Butowski NA, Nelson SJ
• Glioblastoma multiforme regional genetic and cellular expression patterns: influence on anatomic and physiologic MR imaging.
  Radiology 2010 Barajas RF, Hodgson JG, Chang JS, Vandenberg SR, Yeh RF, Parsa AT, McDermott MW, Berger MS, Dillon WP, Cha S
• Multiparametric characterization of grade 2 glioma subtypes using magnetic resonance spectroscopic, perfusion, and diffusion imaging.
  Translational oncology 2009 Bian W, Khayal IS, Lupo JM, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ
• Tumor regrowth between surgery and initiation of adjuvant therapy in patients with newly diagnosed glioblastoma.
  Neuro-oncology 2009 Pirzkall A, McGue C, Saraswathy S, Cha S, Liu R, Vandenberg S, Lamborn KR, Berger MS, Chang SM, Nelson SJ
• Acetabular labral tears in patients with sports injury.
  Clinics in orthopedic surgery 2009 Kang C, Hwang DS, Cha SM
• Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging.
  Radiology 2009 Barajas RF, Chang JS, Segal MR, Parsa AT, McDermott MW, Berger MS, Cha S
• Adult-onset drug-refractory seizure disorder associated with anti-voltage-gated potassium-channel antibody.
  Epilepsia 2009 Barajas RF, Collins DE, Cha S, Geschwind MD
• Neuroimaging in neuro-oncology.
  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2009 Cha S
• Apparent diffusion coefficient and fractional anisotropy of newly diagnosed grade II gliomas.
  NMR in biomedicine 2009 Khayal IS, McKnight TR, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ
• Integration of preoperative anatomic and metabolic physiologic imaging of newly diagnosed glioma.
  Journal of neuro-oncology 2009 Chang SM, Nelson S, Vandenberg S, Cha S, Prados M, Butowski N, McDermott M, Parsa AT, Aghi M, Clarke J, Berger M
• Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM.
  Journal of neuro-oncology 2008 Crawford FW, Khayal IS, McGue C, Saraswathy S, Pirzkall A, Cha S, Lamborn KR, Chang SM, Berger MS, Nelson SJ
• Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy.
  Journal of neuro-oncology 2008 Saraswathy S, Crawford FW, Lamborn KR, Pirzkall A, Chang S, Cha S, Nelson SJ
• Longitudinal magnetic resonance imaging features of glioblastoma multiforme treated with radiotherapy with or without brachytherapy.
  International journal of radiation oncology, biology, physics 2008 Aiken AH, Chang SM, Larson D, Butowski N, Cha S
• Relationship between choline and apparent diffusion coefficient in patients with gliomas.
  Journal of magnetic resonance imaging : JMRI 2008 Khayal IS, Crawford FW, Saraswathy S, Lamborn KR, Chang SM, Cha S, McKnight TR, Nelson SJ
• Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas.
  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, Tihan T, Vandenberg S, McDermott MW, Berger MS
• Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype.
  Neuro-oncology 2007 Lim DA, Cha S, Mayo MC, Chen MH, Keles E, VandenBerg S, Berger MS
• 3D 1H MRSI of brain tumors at 3.0 Tesla using an eight-channel phased-array head coil.
  Journal of magnetic resonance imaging : JMRI 2007 Osorio JA, Ozturk-Isik E, Xu D, Cha S, Chang S, Berger MS, Vigneron DB, Nelson SJ
• Genetic aberrations in gliomatosis cerebri.
  Neurosurgery 2007 Ware ML, Hirose Y, Scheithauer BW, Yeh RF, Mayo MC, Smith JS, Chang S, Cha S, Tihan T, Feuerstein BG
• A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells.
  Nature cell biology 2006 Yook JI, Li XY, Ota I, Hu C, Kim HS, Kim NH, Cha SY, Ryu JK, Choi YJ, Kim J, Fearon ER, Weiss SJ
• Considerations in applying 3D PRESS H-1 brain MRSI with an eight-channel phased-array coil at 3 T.
  Magnetic resonance imaging 2006 Li Y, Osorio JA, Ozturk-Isik E, Chen AP, Xu D, Crane JC, Cha S, Chang S, Berger MS, Vigneron DB, Nelson SJ
• Feasibility of dynamic susceptibility contrast perfusion MR imaging at 3T using a standard quadrature head coil and eight-channel phased-array coil with and without SENSE reconstruction.
  Journal of magnetic resonance imaging : JMRI 2006 Lupo JM, Lee MC, Han ET, Cha S, Chang SM, Berger MS, Nelson SJ
• Unaliasing lipid contamination for MR spectroscopic imaging of gliomas at 3T using sensitivity encoding (SENSE).
  Magnetic resonance in medicine 2006 Ozturk-Isik E, Crane JC, Cha S, Chang SM, Berger MS, Nelson SJ
• Diffusion-weighted MR imaging abnormalities in pediatric patients with surgically-treated intracranial mass lesions.
  Journal of neuro-oncology 2006 Smith JS, Lin H, Mayo MC, Bannerjee A, Gupta N, Perry V, Cha S
• CNS tumors: monitoring therapeutic response and outcome prediction.
  Topics in magnetic resonance imaging : TMRI 2006 Cha S
• Partial-volume model for determining white matter and gray matter cerebral blood volume for analysis of gliomas.
  Journal of magnetic resonance imaging : JMRI 2006 Lee MC, Cha S, Chang SM, Nelson SJ
• Dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in pediatric patients.
  Neuroimaging clinics of North America 2006 Cha S
• Management of a sporadic malignant subfrontal peripheral nerve sheath tumor.
  Journal of neuro-oncology 2006 Sanchez-Mejia RO, Pham DN, Prados M, Tihan T, Cha S, El-Sayed I, McDermott MW
• Radiographic features of intramedullary spinal cord tumors.
  Neurosurgery clinics of North America 2006 Waldron JS, Cha S
• Serial diffusion-weighted magnetic resonance imaging in cases of glioma: distinguishing tumor recurrence from postresection injury.
  Journal of neurosurgery 2005 Smith JS, Cha S, Mayo MC, McDermott MW, Parsa AT, Chang SM, Dillon WP, Berger MS
• Dynamic susceptibility contrast perfusion imaging of radiation effects in normal-appearing brain tissue: changes in the first-pass and recirculation phases.
  Journal of magnetic resonance imaging : JMRI 2005 Lee MC, Cha S, Chang SM, Nelson SJ
• Dynamic susceptibility-weighted perfusion imaging of high-grade gliomas: characterization of spatial heterogeneity.
  AJNR. American journal of neuroradiology 2005 Lupo JM, Cha S, Chang SM, Nelson SJ
• Quantitative apparent diffusion coefficients and T2 relaxation times in characterizing contrast enhancing brain tumors and regions of peritumoral edema.
  Journal of magnetic resonance imaging : JMRI 2005 Oh J, Cha S, Aiken AH, Han ET, Crane JC, Stainsby JA, Wright GA, Dillon WP, Nelson SJ
• Longitudinal multivoxel MR spectroscopy study of pediatric diffuse brainstem gliomas treated with radiotherapy.
  International journal of radiation oncology, biology, physics 2005 Laprie A, Pirzkall A, Haas-Kogan DA, Cha S, Banerjee A, Le TP, Lu Y, Nelson S, McKnight TR
• Update on brain tumor imaging.
  Current neurology and neuroscience reports 2005 Cha S
• Relationship of MR-derived lactate, mobile lipids, and relative blood volume for gliomas in vivo.
  AJNR. American journal of neuroradiology 2005 Li X, Vigneron DB, Cha S, Graves EE, Crawford F, Chang SM, Nelson SJ
• Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging.
  AJNR. American journal of neuroradiology 2005 Cha S, Tihan T, Crawford F, Fischbein NJ, Chang S, Bollen A, Nelson SJ, Prados M, Berger MS, Dillon WP
• Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma.
  Journal of neurosurgery 2005 Parney IF, Kunwar S, McDermott M, Berger M, Prados M, Cha S, Croteau D, Puri RK, Chang SM
• Perfusion MR imaging of brain tumors.
  Topics in magnetic resonance imaging : TMRI 2004 Cha S
• Radiation-induced atypical meningioma with rapid growth in a 13-year-old girl. Case report.
  Journal of neurosurgery 2004 Ware ML, Cha S, Gupta N, Perry VL
• Perfusion MR imaging: basic principles and clinical applications.
  Magnetic resonance imaging clinics of North America 2003 Cha S
• Imaging glioblastoma multiforme.
  Cancer journal (Sudbury, Mass.) 2003 Nelson SJ, Cha S
• Increased expression of cyclin G1 in leiomyoma compared with normal myometrium.
  American journal of obstetrics and gynecology 2003 Baek WK, Kim D, Jung N, Yi YW, Kim JM, Cha SD, Bae I, Cho CH