Sailaja Peddada, PhD
Specialist
Biochemistry and Biophysics
School of Medicine

Publications (8)

Top publication keywords:
Inhibitor of Differentiation ProteinsSOXB1 Transcription FactorsEarly Growth Response Protein 2Chromosome PairingProtein Processing, Post-TranslationalChromatin ImmunoprecipitationInhibitor of Differentiation Protein 1AcetylglucosamineKidney TubulesGenome-Wide Association StudyRegulatory Sequences, Nucleic AcidGene Expression RegulationPluripotent Stem CellsRett SyndromeMethyl-CpG-Binding Protein 2

• Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function.
  Nature genetics 2024 Loeb GB, Kathail P, Shuai RW, Chung R, Grona RJ, Peddada S, Sevim V, Federman S, Mader K, Chu AY, Davitte J, Du J, Gupta AR, Ye CJ, Shafer S, Przybyla L, Rapiteanu R, Ioannidis NM, Reiter JF
• Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function.
  bioRxiv : the preprint server for biology 2024 Loeb GB, Kathail P, Shuai R, Chung R, Grona RJ, Peddada S, Sevim V, Federman S, Mader K, Chu A, Davitte J, Du J, Gupta AR, Ye CJ, Shafer S, Przybyla L, Rapiteanu R, Ioannidis N, Reiter JF
• Functional genomics in stem cell models: considerations and applications.
  Frontiers in cell and developmental biology 2023 Shevade K, Peddada S, Mader K, Przybyla L
• SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells.
  eLife 2016 Myers SA, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, Thomas S, Maynard J, Broeker M, Thomson M, Pollard K, Yamanaka S, Burlingame AL, Panning B
• Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism.
  Human molecular genetics 2008 Swanberg SE, Nagarajan RP, Peddada S, Yasui DH, LaSalle JM
• Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes.
  Proceedings of the National Academy of Sciences of the United States of America 2007 Yasui DH, Peddada S, Bieda MC, Vallero RO, Hogart A, Nagarajan RP, Thatcher KN, Farnham PJ, Lasalle JM
• Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome.
  Human molecular genetics 2006 Peddada S, Yasui DH, LaSalle JM
• Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples.
  Human molecular genetics 2005 Thatcher KN, Peddada S, Yasui DH, Lasalle JM