Siegrid Yu, MD
Professor
Dermatology
School of Medicine

In her research, Yu investigates Merkel cell carcinoma and other skin cancers as well as skin cancer in immunosuppressed patients. Her research honors include the Clinical Career Development Award in Dermatologic Surgery from the Dermatology Foundation.

Yu earned her medical degree at the University of Washington. She completed a residency in internal medicine at Stanford Medicine, where she served as chief resident. She completed a residency in dermatology at UCSF, where she also was chief resident, and a fellowship in Mohs surgery and procedural dermatology at UCSF.

Yu is a member of the American Society of Dermatologic Surgery (ASDS) and has received an ASDS Cutting Edge Research Grant. She also is a member of the American Academy of Dermatology, American College of Mohs Surgery and American Medical Association. She serves as director of UCSF’s fellowship program in procedural dermatology.

• A case report of 2 patients developing multiple Merkel cell carcinomas-using comparative genomic hybridization to elucidate tumor relationship.
  JAAD case reports 2022 Lowenstein SE, Lohman ME, Yu SS
• Skin Color Match in Head and Neck Reconstructive Surgery.
  The Laryngoscope 2021 Knott PD, Alemi SA, Han M, Seth R, Park AM, Heaton CM, Grekin RC, Arron ST, Neuhaus I, Yu SS, Saylor DK, Zhu BZ
• Should Sentinel Lymph Node Biopsy Status Guide Adjuvant Radiation Therapy in Patients With Merkel Cell Carcinoma?
  Advances in radiation oncology 2021 Ahmad TR, Vasudevan HN, Lazar AA, Chan JW, George JR, Alvarado MD, Yu SS, Daud A, Yom SS
• Characterization of the 2019 Micrographic Surgery and Dermatologic Oncology Standardized Letter of Recommendation.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2021 Abidi NY, Wanner B, Brown M, Golda N, Hajar T, Rohani P, Yu SS, Carr DR
• Development of international clinical practice guidelines: benefits, limitations, and alternative forms of international collaboration.
  Archives of dermatological research 2020 Alam M, Harikumar V, Kang BY, Ibrahim SA, Kibbi N, Owen JL, Maher IA, Cartee TV, Sobanko JF, Reynolds KA, Bolotin D, Waldman AH, Minkis K, Petersen B, Council ML, Nehal KS, Xu YG, Jiang SB, Somani AK,…
• Principles for developing and adapting clinical practice guidelines and guidance for pandemics, wars, shortages, and other crises and emergencies: the PAGE criteria.
  Archives of dermatological research 2020 Alam M, Harikumar V, Ibrahim SA, Kang BY, Maher IA, Cartee TV, Sobanko JF, Kibbi N, Owen JL, Reynolds KA, Bolotin D, Waldman AH, Minkis K, Petersen B, Council ML, Nehal KS, Xu YG, Jiang SB, Somani AK,…
• Broad versus narrow clinical practice guidelines: avoiding rules for the high risk 1.
  Archives of dermatological research 2020 Harikumar V, Worley B, Ibrahim SA, Kang BY, Maher IA, Cartee TV, Sobanko JF, Kibbi N, Owen JL, Reynolds KA, Bolotin D, Waldman AH, Minkis K, Petersen B, Council ML, Nehal KS, Xu YG, Jiang SB, Somani …
• A Review of the Use of Telemedicine in Dermatologic Surgery.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2020 Sohn GK, Wong DJ, Yu SS
• Validation of the English Basal and Squamous Cell Carcinoma Quality of Life (BaSQoL) Questionnaire.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2020 Yu WY, Waalboer-Spuij R, Bremer R, Lu B, Aroyan C, Crow L, Grekin R, Neuhaus I, Yu S, Arron ST, Hollestein LM
• Effect of Topical Brimonidine on Alcohol-Induced Flushing in Asian Individuals: A Randomized Clinical Trial.
  JAMA dermatology 2020 Yu WY, Lu B, Tan D, Aroyan C, Shinkai K, Leslie KS, Fox LP, Yu S, Neuhaus IM, Grekin RC, Arron ST
• Sebaceous carcinoma: evidence-based clinical practice guidelines.
  The Lancet. Oncology 2019 Owen JL, Kibbi N, Worley B, Kelm RC, Wang JV, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw SH, Cartee TV, Chandra S, Cho NL, Choi JN, Council ML, Demirci H, Eisen DB, Esmaeli …
• Recent advances in Merkel cell carcinoma.
  F1000Research 2019 Robinson CG, Tan D, Yu SS
• Cranial neuropathies as the presenting symptom of cutaneous squamous cell carcinoma.
  JAAD case reports 2019 Sipprell WH, Yu WY, Yu SS
• Evidence-Based Clinical Practice Guidelines for Microcystic Adnexal Carcinoma: Informed by a Systematic Review.
  JAMA dermatology 2019 Worley B, Owen JL, Barker CA, Behshad R, Bichakjian CK, Bolotin D, Bordeaux JS, Bradshaw S, Cartee TV, Chandra S, Cho N, Choi J, Council ML, Eisen DB, Golda N, Huang CC, Ibrahim SF, Jiang SIB, Kim J, …
• Atypical Fibroxanthoma.
  Seminars in cutaneous medicine and surgery 2019 Chapman LW, Yu SS, Arron ST
• Introduction, High-Risk Skin Cancer.
  Seminars in cutaneous medicine and surgery 2019 Yu SS
• Vulvar basal cell carcinoma in a patient with long-standing lichen sclerosus.
  JAAD case reports 2018 Comstock JR, Woodruff CM, Yu SS, Kornik RI
• Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution.
  Cell reports 2018 Cheng JB, Sedgewick AJ, Finnegan AI, Harirchian P, Lee J, Kwon S, Fassett MS, Golovato J, Gray M, Ghadially R, Liao W, Perez White BE, Mauro TM, Mully T, Kim EA, Sbitany H, Neuhaus IM, Grekin RC, Yu …
• In-field and abscopal response after short-course radiation therapy in patients with metastatic Merkel cell carcinoma progressing on PD-1 checkpoint blockade: a case series.
  Journal for immunotherapy of cancer 2018 Xu MJ, Wu S, Daud AI, Yu SS, Yom SS
• 828 Reversal of a core, keratinocyte-autonomous inflammatory program linking diverse cutaneous rashes.
  Journal of Investigative Dermatology 2018 J. Cheng, A. Sedgewick, P. Harirchian, J. Lee, S. Benz, C. Vaske, E. Kim, H. Sbitany, I. Neuhaus, S. Yu, R. Grekin, B.E. Perez White, W. Liao, T. Mauro, R. Cho
• Simple Technique to Optimize Second-Intention Healing of Nasal Alar and Tip Defects.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2018 Levin EC, Sofen B, Yu S
• Merkel cell carcinoma: An update and review: Current and future therapy.
  Journal of the American Academy of Dermatology 2017 Tello TL, Coggshall K, Yom SS, Yu SS
• Merkel cell carcinoma: An update and review: Pathogenesis, diagnosis, and staging.
  Journal of the American Academy of Dermatology 2017 Coggshall K, Tello TL, North JP, Yu SS
• Mental Artery Occlusion From Poly-L-Lactic Acid Injection at the Lateral Chin.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2017 Yuan JT, Chang TW, Yu SS, Arron ST
• Comparison of W-Plasty vs Traditional Straight-Line Techniques for Primary Paramedian Forehead Flap Donor Site Closure.
  JAMA facial plastic surgery 2016 Jáuregui EJ, Tummala N, Seth R, Arron S, Neuhaus I, Yu S, Grekin R, Knott PD
• Antiaging Cosmeceuticals.
  International Textbook of Aesthetic Surgery 2016 Lily Talakoub, Isaac M. Neuhaus, Siegrid S. Yu
• Prospective evaluation of complications in dermatologic surgery associated with hypertension Conroy.
  Dermatology Online Journal 2016 Conroy Chow, Matthew J Simpson, Niko Pascua, Harjot Maan, Jacqueline G Berlier, Siegrid Yu, Isaac Neuhaus, Roy Grekin, Sarah T Arron
• Management of Merkel Cell Carcinoma.
  Current Dermatology Reports 2015 Jennifer L. Herrmann, Siegrid S. Yu
• Merkel cell carcinoma in organ transplant recipients: Case reports and review of the literature.
  JAAD case reports 2015 Garrett GL, Zargham H, Schulman JM, Jafarian F, Yu SS, Arron ST
• Multiple cutaneous collagenomas in the setting of multiple endocrine neoplasia type 1.
  Journal of cutaneous pathology 2015 Pérez AD, Yu S, North JP
• Advances in Management of Merkel Cell Carcinoma in Organ Transplant Recipients: Role of Polyoma Virus and Immunosuppression.
  Advances in Transplant Dermatology 2015 Kathryn Serowka, Sarah Arron, Siegrid S. Yu
• Non-tuberculous mycobacterial infections following cosmetic laser procedures: a case report and review of the literature.
  Journal of drugs in dermatology : JDD 2015 Berliner JG, Aldabagh B, Mully T, Yu SS, Schwartz BS, Berger TG
• Organ transplant recipients with Merkel cell carcinoma have reduced progression-free, overall, and disease-specific survival independent of stage at presentation.
  Journal of the American Academy of Dermatology 2014 Arron ST, Canavan T, Yu SS
• Merkel cell carcinoma: current status of targeted and future potential for immunotherapies.
  Seminars in cutaneous medicine and surgery 2014 Aldabagh B, Joo J, Yu SS
• Memory regulatory T cells reside in human skin.
  The Journal of clinical investigation 2014 Sanchez Rodriguez R, Pauli ML, Neuhaus IM, Yu SS, Arron ST, Harris HW, Yang SH, Anthony BA, Sverdrup FM, Krow-Lucal E, MacKenzie TC, Johnson DS, Meyer EH, Löhr A, Hsu A, Koo J, Liao W, Gupta R, …
• Relationships among primary tumor size, number of involved nodes, and survival for 8044 cases of Merkel cell carcinoma.
  Journal of the American Academy of Dermatology 2014 Iyer JG, Storer BE, Paulson KG, Lemos B, Phillips JL, Bichakjian CK, Zeitouni N, Gershenwald JE, Sondak V, Otley CC, Yu SS, Johnson TM, Liegeois NJ, Byrd D, Sober A, Nghiem P
• 18F-fluorodeoxyglucose positron emission tomography-computed tomography imaging in the management of Merkel cell carcinoma: a single-institution retrospective study.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2013 Ibrahim SF, Ahronowitz I, McCalmont TH, Hernandez Pampaloni M, Ryan JL, Yu SS
• Case Study B: Radiation Monotherapy for Extensive Local and In-Transit Merkel Cell Carcinoma.
  Merkel Cell Carcinoma 2013 Sherrif F. Ibrahim, Sue S. Yom, Siegrid S. Yu
• Case Study D: Evaluation of Multiple Merkel Cell Carcinomas in a Single Patient.
  Merkel Cell Carcinoma 2013 Iris Ahronowitz, Siegrid S. Yu
• Clinical Diagnosis.
  Merkel Cell Carcinoma 2013 Nancy Kim, Sandra Y. Han, Siegrid S. Yu
• Staging.
  Merkel Cell Carcinoma 2013 Sherrif F. Ibrahim, Siegrid S. Yu
• Importance of genetic studies in patients with multiple merkel cell carcinomas.
  Acta dermato-venereologica 2012 Ahronowitz I, Nghiem P, Yu S
• Tobacco smoking and dermatologic surgery.
  Journal of the American Academy of Dermatology 2012 Gill JF, Yu SS, Neuhaus IM
• Merkel cell carcinoma.
  Hematology/oncology clinics of North America 2012 Han SY, North JP, Canavan T, Kim N, Yu SS
• Immunohistochemical prognostication of Merkel cell carcinoma: p63 expression but not polyomavirus status correlates with outcome.
  Journal of cutaneous pathology 2012 Hall BJ, Pincus LB, Yu SS, Oh DH, Wilson AR, McCalmont TH
• Prevention and Treatment of Bleeding Complications in Dermatologic Surgery.
  Evidence-Based Procedural Dermatology 2012 Murray A. Cotter, Siegrid S. Yu, Isaac M. Neuhaus
• Second-intention healing of nasal alar defects.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2011 Neuhaus IM, Yu SS
• An isolated Merkel cell carcinoma metastasis at a distant cutaneous site presenting as a second 'primary' tumor.
  Journal of cutaneous pathology 2011 Ahronowitz IZ, Daud AI, Leong SP, Shue EH, Bastian BC, McCalmont TH, Yu SS
• A new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: creation and rationale for inclusion of tumor (T) characteristics.
  Journal of the American Academy of Dermatology 2011 Farasat S, Yu SS, Neel VA, Nehal KS, Lardaro T, Mihm MC, Byrd DR, Balch CM, Califano JA, Chuang AY, Sharfman WH, Shah JP, Nghiem P, Otley CC, Tufaro AP, Johnson TM, Sober AJ, Liégeois NJ
• Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system.
  Journal of the American Academy of Dermatology 2010 Lemos BD, Storer BE, Iyer JG, Phillips JL, Bichakjian CK, Fang LC, Johnson TM, Liegeois-Kwon NJ, Otley CC, Paulson KG, Ross MI, Yu SS, Zeitouni NC, Byrd DR, Sondak VK, Gershenwald JE, Sober AJ, Nghiem…
• Adenosquamous carcinoma of the skin: a case series.
  Archives of dermatology 2009 Fu JM, McCalmont T, Yu SS
• Chapter 2 Cosmeceuticals.
  2009 Lily Talakoub, Isaac M. Neuhaus, Siegrid S. Yu
• Case 19-2008: Merkel-cell carcinoma.
  The New England journal of medicine 2008 Lemos BD, Yu SS, Nghiem P
• Reply.
  Dermatologic Surgery 2008 NAISSAN O. WESLEY, SIEGRID S. YU, ROY C. GREKIN, ISAAC M. NEUHAUS
• The presence of polyomavirus in non-melanoma skin cancer in organ transplant recipients is rare.
  The Journal of investigative dermatology 2008 Ridd K, Yu S, Bastian BC
• Primary Linear Closure for Large Defects of the Nasal Supratip.
  Dermatologic Surgery 2008 NAISSAN O. WESLEY, SIEGRID S. YU, ROY C. GREKIN, ISAAC M. NEUHAUS
• Primary linear closure for large defects of the nasal supratip.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2008 Wesley NO, Yu SS, Grekin RC, Neuhaus IM
• Bleeding complications in dermatologic surgery.
  Seminars in cutaneous medicine and surgery 2007 Hurst EA, Yu SS, Grekin RC, Neuhaus IM
• Aesthetic analysis of Asian skin.
  Facial plastic surgery clinics of North America 2007 Yu SS, Grekin RC
• Diagnosis and treatment of pigmentary disorders in Asian skin.
  Facial plastic surgery clinics of North America 2007 Yu SS, Pai S, Neuhaus IM, Grekin RC
• Bleeding complications in dermatologic surgery.
  Seminars in cutaneous medicine and surgery 2007 Hurst EA, Yu SS, Grekin RC, Neuhaus IM
• Infectious complications and antibiotic use in dermatologic surgery.
  Seminars in cutaneous medicine and surgery 2007 Hurst EA, Grekin RC, Yu SS, Neuhaus IM
• Dermatitis herpetiformis associated with administration of a gonadotropin-releasing hormone analog.
  Journal of the American Academy of Dermatology 2006 Yu SS, Connolly MK, Berger TG, McCalmont TH
• Cardiac Devices and Electromagnetic Interference Revisited.
  Dermatologic Surgery 2005 Siegrid S. Yu, Whitney D. Tope, Roy C. Grekin
• Cardiac devices and electromagnetic interference revisited: new radiofrequency technologies and implications for dermatologic surgery.
  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 2005 Yu SS, Tope WD, Grekin RC
• Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy.
  AIDS (London, England) 2004 Mafong DD, Lee GA, Yu S, Tien P, Mauro T, Grunfeld C