Shibani Pati, MD, PhD
Professor
Laboratory Medicine
School of Medicine

I am by training a translational vascular biologist with an interest in the role of endothelial dysfunction and vascular compromise in the pathogenesis of human disease. My specific areas of investigation involve the use of stem cell therapies and novel resuscitation modalities that can mitigate endothelial dysfunction and improve outcomes in traumatic injury. Areas of focus in the lab include traumatic brain injury (TBI) and hemorrhagic shock-induced organ failure.

Abnormalities in vascular permeability leading to inflammation, tissue edema, and end-organ dysfunction significantly contribute to the morbidity and mortality associated with a number of human disease processes. For example, although a number of factors contribute to the high mortality and morbidity associated with traumatic brain injury (TBI), the development of cerebral edema with brain swelling remains one of the most significant predictors of outcome. Similarly, both hemorrhagic shock and septic shock are characterized by abnormal vascular permeability, which contributes to the development of shock-associated acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Despite the clear importance of abnormal vascular permeability in a number of human disease processes, there exists no therapeutic modality in current use to attenuate it. Our lab's focus is to understand the mechanisms of action that lead to organ failure in traumatic injury and to also discover novel therapies that improve outcomes. We are and have been part of number of pre-clinical and clinical trials investigating the therapeutic potential of stem cells, stem cell derived factors and novel blood products. This has led to exciting new avenues for the discovery of novel therapeutic agents that mitigate vascular injury.

• Lyophilized plasma resuscitation downregulates inflammatory gene expression in a mouse model of sepsis.
  The journal of trauma and acute care surgery 2022 Barry M, Wu F, Pati S, Chipman A, Geng H, Kozar R
• FFP maintains normal coagulation while Kcentra induces a hypercoagulable state in a porcine model of pulmonary contusion and hemorrhagic shock.
  The journal of trauma and acute care surgery 2022 Dixon A, Beiling M, Smith S, Behrens B, Appleman L, Rick E, Murphy J, Madtson B, McCully B, Goodman A, Kanlerd A, Schaller T, Subramanian S, Trivedi A, Pati S, Schreiber M
• Mesenchymal stem cell extracellular vesicles mitigate vascular permeability and injury in the small intestine and lung in a mouse model of hemorrhagic shock and trauma.
  The journal of trauma and acute care surgery 2022 Barry M, Trivedi A, Pathipati P, Miyazawa BY, Vivona LR, Togarrati PP, Khakoo M, Tanner H, Norris P, Pati S
• Treating the endotheliopathy of SARS-CoV-2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products.
  Transfusion 2021 Pati S, Fennern E, Holcomb JB, Barry M, Trivedi A, Cap AP, Martin MJ, Wade C, Kozar R, Cardenas JC, Rappold JF, Spiegel R, Schreiber MA
• Cryoprecipitate attenuates the endotheliopathy of trauma in mice subjected to hemorrhagic shock and trauma.
  The journal of trauma and acute care surgery 2021 Barry M, Trivedi A, Miyazawa BY, Vivona LR, Khakoo M, Zhang H, Pathipati P, Bagri A, Gatmaitan MG, Kozar R, Stein D, Pati S
• Evidence-Based and Clinically Relevant Outcomes for Hemorrhage Control Trauma Trials.
  Annals of surgery 2021 Holcomb JB, Moore EE, Sperry JL, Jansen JO, Schreiber MA, Del Junco DJ, Spinella PC, Sauaia A, Brohi K, Bulger EM, Cap AP, Hess JR, Jenkins D, Lewis RJ, Neal MD, Newgard C, Pati S, Pusateri AE, Rizoli…
• Freeze-dried platelets promote clot formation, attenuate endothelial cell permeability, and decrease pulmonary vascular leak in a murine model of hemorrhagic shock.
  The journal of trauma and acute care surgery 2021 Trivedi A, Potter DR, Miyazawa BY, Lin M, Vivona LR, Khakoo MA, Antebi B, Lee A, Ishler B, Dickerson M, Kozar R, Schreiber MA, Holcomb JB, Fitzpatrick GM, Pati S
• The effects of human prothrombin complex concentrate on hemorrhagic shock-induced lung injury in rats: Implications for testing human blood products in rodents.
  The journal of trauma and acute care surgery 2020 Potter DR, Trivedi A, Lin M, Miyazawa BY, Vivona LR, McCully B, Nair A, Schreiber MA, Pati S
• Fresh frozen plasma attenuates lung injury in a novel model of prolonged hypotensive resuscitation.
  The journal of trauma and acute care surgery 2020 Chipman AM, Wu F, Pati S, Burdette AJ, Glaser JJ, Kozar RA
• Resuscitative Strategies to Modulate the Endotheliopathy of Trauma: From Cell to Patient.
  Shock (Augusta, Ga.) 2020 Wu F, Chipman A, Pati S, Miyasawa B, Corash L, Kozar RA
• Aggressive treatment of acute kidney injury and hyperkalemia improves survival in a combat relevant trauma model in swine.
  American journal of surgery 2020 Smith S, Behrens B, McCully B, Murphy J, Bommiasamy A, Goodman A, Dewey E, Pati S, Schreiber M
• Is all plasma created equal? A pilot study of the effect of interdonor variability.
  The journal of trauma and acute care surgery 2020 Chipman AM, Pati S, Potter D, Wu F, Lin M, Kozar RA
• Platelet-derived- Extracellular Vesicles Promote Hemostasis and Prevent the Development of Hemorrhagic Shock.
  Scientific reports 2019 Lopez E, Srivastava AK, Burchfield J, Wang YW, Cardenas JC, Togarrati PP, Miyazawa B, Gonzalez E, Holcomb JB, Pati S, Wade CE
• Gaps in the knowledge of human platelet lysate as a cell culture supplement for cell therapy: a joint publication from the AABB and the International Society for Cell & Gene Therapy.
  Transfusion 2019 Bieback K, Fernandez-Muñoz B, Pati S, Schäfer R
• Regulation of endothelial cell permeability by platelet-derived extracellular vesicles.
  The journal of trauma and acute care surgery 2019 Miyazawa B, Trivedi A, Togarrati PP, Potter D, Baimukanova G, Vivona L, Lin M, Lopez E, Callcut R, Srivastava AK, Kornblith LZ, Fields AT, Schreiber MA, Wade CE, Holcomb JB, Pati S
• Bone marrow donor selection and characterization of MSCs is critical for pre-clinical and clinical cell dose production.
  Journal of translational medicine 2019 Trivedi A, Miyazawa B, Gibb S, Valanoski K, Vivona L, Lin M, Potter D, Stone M, Norris PJ, Murphy J, Smith S, Schreiber M, Pati S
• Regulation of Endothelial Cell Permeability by Platelet-Derived Extracellular Vesicles.
  The journal of trauma and acute care surgery 2019 Miyazawa B, Trivedi A, Togarrati PP, Potter D, Baimukanova G, Vivona L, Lin M, Lopez E, Callcut R, Srivastava AK, Kornblith LZ, Fields AT, Schreiber MA, Wade CE, Holcomb JB, Pati S
• Introduction to the supplement on cellular therapies in trauma and critical care medicine.
  Transfusion 2019 Pati S, Schreiber M, Rappold J
• Barriers to clinical research in trauma.
  Transfusion 2018 Miskimins R, Pati S, Schreiber M
• Multipotent Adult Progenitor Cells, but Not Tissue Inhibitor of Matrix Metalloproteinase-3, Increase Tissue Sparing and Reduce Urological Complications following Spinal Cord Injury.
  Journal of neurotrauma 2018 Jones JM, DePaul MA, Gregory CR, Lang BT, Xie H, Zhu M, Rutten MJ, Mays RW, Busch SA, Pati S, Gregory KW
• A combat relevant model for the creation of acute lung injury in swine.
  The journal of trauma and acute care surgery 2018 Smith S, McCully B, Bommiasamy A, Murphy J, Behrens B, Pati S, Goodman A, Schreiber M
• Elevated plasma levels of TIMP-3 are associated with a higher risk of acute respiratory distress syndrome and death following severe isolated traumatic brain injury.
  Trauma surgery & acute care open 2018 Hendrickson CM, Gibb SL, Miyazawa BY, Keating SM, Ross E, Conroy AS, Calfee CS, Pati S, Cohen MJ
• Platelet-Derived Microvesicles: A Potential Therapy for Trauma-Induced Coagulopathy.
  Shock (Augusta, Ga.) 2018 Lopez E, Srivastava AK, Pati S, Holcomb JB, Wade CE
• Cellular therapies and stem cell applications in trauma.
  American journal of surgery 2018 Wang Y, Pati S, Schreiber M
• Lyophilized plasma attenuates vascular permeability, inflammation and lung injury in hemorrhagic shock.
  PloS one 2018 Pati S, Peng Z, Wataha K, Miyazawa B, Potter DR, Kozar RA
• Mesenchymal stem cell-derived extracellular vesicles attenuate pulmonary vascular permeability and lung injury induced by hemorrhagic shock and trauma.
  The journal of trauma and acute care surgery 2018 Potter DR, Miyazawa BY, Gibb SL, Deng X, Togaratti PP, Croze RH, Srivastava AK, Trivedi A, Matthay M, Holcomb JB, Schreiber MA, Pati S
• Plasma Resuscitation Improved Survival in a Cecal Ligation and Puncture Rat Model of Sepsis.
  Shock (Augusta, Ga.) 2018 Chang R, Holcomb JB, Johansson PI, Pati S, Schreiber MA, Wade CE
• Cellular therapies in trauma and critical care medicine: Looking towards the future.
  PLoS medicine 2017 Pati S, Rasmussen TE
• Resuscitation of Hypotensive Traumatic Brain Injured Animals With Spray-Dried Plasma Does Not Adversely Alter Physiology and Improves Blood-Brain Barrier Function.
  Military medicine 2017 McDaniel S, Golla S, Moore AN, DaCorta J, Bode A, Pati S, Dash PK, Zhao J
• Serum from dengue virus-infected patients with and without plasma leakage differentially affects endothelial cells barrier function in vitro.
  PloS one 2017 Tramontini Gomes de Sousa Cardozo F, Baimukanova G, Lanteri MC, Keating SM, Moraes Ferreira F, Heitman J, Pannuti CS, Pati S, Romano CM, Cerdeira Sabino E
• Concise Review: Mesenchymal Stem (Stromal) Cells: Biology and Preclinical Evidence for Therapeutic Potential for Organ Dysfunction Following Trauma or Sepsis.
  Stem cells (Dayton, Ohio) 2017 Matthay MA, Pati S, Lee JW
• Lack of species-specific difference in pulmonary function when using mouse versus human plasma in a mouse model of hemorrhagic shock.
  The journal of trauma and acute care surgery 2016 Peng Z, Pati S, Fontaine MJ, Hall K, Herrera AV, Kozar RA
• Plasma Transfusion: History, Current Realities, and Novel Improvements.
  Shock (Augusta, Ga.) 2016 Watson JJ, Pati S, Schreiber MA
• Wnt3a, a Protein Secreted by Mesenchymal Stem Cells Is Neuroprotective and Promotes Neurocognitive Recovery Following Traumatic Brain Injury.
  Stem cells (Dayton, Ohio) 2016 Zhao Y, Gibb SL, Zhao J, Moore AN, Hylin MJ, Menge T, Xue H, Baimukanova G, Potter D, Johnson EM, Holcomb JB, Cox CS, Dash PK, Pati S
• Dried plasma: state of the science and recent developments.
  Transfusion 2016 Pusateri AE, Given MB, Schreiber MA, Spinella PC, Pati S, Kozar RA, Khan A, Dacorta JA, Kupferer KR, Prat N, Pidcoke HF, Macdonald VW, Malloy WW, Sailliol A, Cap AP
• Modulating the endotheliopathy of trauma: Factor concentrate versus fresh frozen plasma.
  The journal of trauma and acute care surgery 2016 Pati S, Potter DR, Baimukanova G, Farrel DH, Holcomb JB, Schreiber MA
• Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets.
  Transfusion 2016 Baimukanova G, Miyazawa B, Potter DR, Muench MO, Bruhn R, Gibb SL, Spinella PC, Cap AP, Cohen MJ, Pati S
• The effects of 22°C and 4°C storage of platelets on vascular endothelial integrity and function.
  Transfusion 2016 Baimukanova G, Miyazawa B, Potter DR, Gibb SL, Keating S, Danesh A, Beyer A, Dayter Y, Bruhn R, Muench MO, Cap AP, Norris PJ, Spinella P, Cohen M, Pati S
• Cellular Therapies in Trauma and Critical Care Medicine: Forging New Frontiers.
  Shock (Augusta, Ga.) 2015 Pati S, Pilia M, Grimsley JM, Karanikas AT, Oyeniyi B, Holcomb JB, Cap AP, Rasmussen TE
• Plasma-Mediated Gut Protection After Hemorrhagic Shock is Lessened in Syndecan-1-/- Mice.
  Shock (Augusta, Ga.) 2015 Ban K, Peng Z, Pati S, Witkov RB, Park PW, Kozar RA
• TIMP3 Attenuates the Loss of Neural Stem Cells, Mature Neurons and Neurocognitive Dysfunction in Traumatic Brain Injury.
  Stem cells (Dayton, Ohio) 2015 Gibb SL, Zhao Y, Potter D, Hylin MJ, Bruhn R, Baimukanova G, Zhao J, Xue H, Abdel-Mohsen M, Pillai SK, Moore AN, Johnson EM, Cox CS, Dash PK, Pati S
• Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock.
  The journal of trauma and acute care surgery 2015 Potter DR, Baimukanova G, Keating SM, Deng X, Chu JA, Gibb SL, Peng Z, Muench MO, Fomin ME, Spinella PC, Kozar R, Pati S
• Syndecan-1 restitution by plasma after hemorrhagic shock.
  The journal of trauma and acute care surgery 2015 Kozar RA, Pati S
• Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients.
  Journal of translational medicine 2015 Rahbar E, Cardenas JC, Baimukanova G, Usadi B, Bruhn R, Pati S, Ostrowski SR, Johansson PI, Holcomb JB, Wade CE
• The whole is greater than the sum of its parts: hemostatic profiles of whole blood variants.
  The journal of trauma and acute care surgery 2014 Kornblith LZ, Howard BM, Cheung CK, Dayter Y, Pandey S, Busch MP, Pati S, Callcut RA, Vilardi RF, Redick BJ, Nelson MF, Cohen MJ
• Never-frozen liquid plasma blocks endothelial permeability as effectively as thawed fresh frozen plasma.
  The journal of trauma and acute care surgery 2014 Cao Y, Dua A, Matijevic N, Wang YW, Pati S, Wade CE, Ko TC, Holcomb JB
• Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps.
  Shock (Augusta, Ga.) 2014 Jenkins DH, Rappold JF, Badloe JF, Berséus O, Blackbourne L, Brohi KH, Butler FK, Cap AP, Cohen MJ, Davenport R, DePasquale M, Doughty H, Glassberg E, Hervig T, Hooper TJ, Kozar R, Maegele M, Moore EE…
• Autologous bone marrow mononuclear cells therapy attenuates activated microglial/macrophage response and improves spatial learning after traumatic brain injury.
  The journal of trauma and acute care surgery 2013 Bedi SS, Walker PA, Shah SK, Jimenez F, Thomas CP, Smith P, Hetz RA, Xue H, Pati S, Dash PK, Cox CS
• Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan 1.
  Shock (Augusta, Ga.) 2013 Peng Z, Pati S, Potter D, Brown R, Holcomb JB, Grill R, Wataha K, Park PW, Xue H, Kozar RA
• Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity.
  Science translational medicine 2013 Chintalgattu V, Rees ML, Culver JC, Goel A, Jiffar T, Zhang J, Dunner K, Pati S, Bankson JA, Pasqualini R, Arap W, Bryan NS, Taegtmeyer H, Langley RR, Yao H, Kupferman ME, Entman ML, Dickinson ME, …
• Optimal trauma resuscitation with plasma as the primary resuscitative fluid: the surgeon's perspective.
  Hematology. American Society of Hematology. Education Program 2013 Holcomb JB, Pati S
• Spray-dried plasma and fresh frozen plasma modulate permeability and inflammation in vitro in vascular endothelial cells.
  Transfusion 2013 Wataha K, Menge T, Deng X, Shah A, Bode A, Holcomb JB, Potter D, Kozar R, Spinella PC, Pati S
• Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury.
  Science translational medicine 2012 Menge T, Zhao Y, Zhao J, Wataha K, Gerber M, Zhang J, Letourneau P, Redell J, Shen L, Wang J, Peng Z, Xue H, Kozar R, Cox CS, Khakoo AY, Holcomb JB, Dash PK, Pati S
• Human mesenchymal stem cells inhibit endothelial proliferation and angiogenesis via cell-cell contact through modulation of the VE-Cadherin/β-catenin signaling pathway.
  Stem cells and development 2012 Menge T, Gerber M, Wataha K, Reid W, Guha S, Cox CS, Dash P, Reitz MS, Khakoo AY, Pati S
• Caffeic Acid phenethyl ester protects blood-brain barrier integrity and reduces contusion volume in rodent models of traumatic brain injury.
  Journal of neurotrauma 2012 Zhao J, Pati S, Redell JB, Zhang M, Moore AN, Dash PK
• Aged plasma transfusion increases mortality in a rat model of uncontrolled hemorrhage.
  The Journal of trauma 2011 Letourneau PA, McManus M, Sowards K, Wang W, Wang YW, Matijevic N, Pati S, Wade CE, Holcomb JB
• Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock.
  PloS one 2011 Pati S, Gerber MH, Menge TD, Wataha KA, Zhao Y, Baumgartner JA, Zhao J, Letourneau PA, Huby MP, Baer LA, Salsbury JR, Kozar RA, Wade CE, Walker PA, Dash PK, Cox CS, Doursout MF, Holcomb JB
• Involvement of the glycogen synthase kinase-3 signaling pathway in TBI pathology and neurocognitive outcome.
  PloS one 2011 Dash PK, Johnson D, Clark J, Orsi SA, Zhang M, Zhao J, Grill RJ, Moore AN, Pati S
• Modulation of syndecan-1 shedding after hemorrhagic shock and resuscitation.
  PloS one 2011 Haywood-Watson RJ, Holcomb JB, Gonzalez EA, Peng Z, Pati S, Park PW, Wang W, Zaske AM, Menge T, Kozar RA
• Increased platelet:RBC ratios are associated with improved survival after massive transfusion.
  The Journal of trauma 2011 Holcomb JB, Zarzabal LA, Michalek JE, Kozar RA, Spinella PC, Perkins JG, Matijevic N, Dong JF, Pati S, Wade CE, Trauma Outcomes Group, Holcomb JB, Wade CE, Cotton BA, Kozar RA, Brasel KJ, Vercruysse …
• Increased transforming growth factor β contributes to deterioration of refrigerated fresh frozen plasma's effects in vitro on endothelial cells.
  Shock (Augusta, Ga.) 2011 Duan C, Cao Y, Deng X, Wang W, Yang W, Liu X, Chen Z, Pati S, Kozar RA, Gonzalez EA, Wade CE, Holcomb JB, Ko TC
• Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock.
  Anesthesia and analgesia 2011 Kozar RA, Peng Z, Zhang R, Holcomb JB, Pati S, Park P, Ko TC, Paredes A
• Human Bone Marrow Derived Mesenchymal Stem Cells Regulate Leukocyte-Endothelial Interactions and Activation of Transcription Factor NF-Kappa B.
  Journal of tissue science & engineering 2011 Letourneau PA, Menge TD, Wataha KA, Wade CE, S Cox C, Holcomb JB, Pati S
• Human mesenchymal stem cells inhibit vascular permeability by modulating vascular endothelial cadherin/β-catenin signaling.
  Stem cells and development 2010 Pati S, Khakoo AY, Zhao J, Jimenez F, Gerber MH, Harting M, Redell JB, Grill R, Matsuo Y, Guha S, Cox CS, Reitz MS, Holcomb JB, Dash PK
• Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes.
  Journal of molecular and cellular cardiology 2010 Rogers TB, Pati S, Gaa S, Riley D, Khakoo AY, Patel S, Wardlow RD, Frederick CA, Hall G, He LP, Lederer WJ
• Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: preserving the blood brain barrier via an interaction with splenocytes.
  Experimental neurology 2010 Walker PA, Shah SK, Jimenez F, Gerber MH, Xue H, Cutrone R, Hamilton JA, Mays RW, Deans R, Pati S, Dash PK, Cox CS
• Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw.
  The Journal of trauma 2010 Pati S, Matijevic N, Doursout MF, Ko T, Cao Y, Deng X, Kozar RA, Hartwell E, Conyers J, Holcomb JB
• Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats.
  PloS one 2010 Dash PK, Orsi SA, Zhang M, Grill RJ, Pati S, Zhao J, Moore AN
• Direct intrathecal implantation of mesenchymal stromal cells leads to enhanced neuroprotection via an NFkappaB-mediated increase in interleukin-6 production.
  Stem cells and development 2010 Walker PA, Harting MT, Jimenez F, Shah SK, Pati S, Dash PK, Cox CS
• Fresh frozen plasma increases adhesion molecule expression on human pulmonary endothelial cells.
  The Journal of surgical research 2010 Letourneau PA, Pati S, Gerber MH, Jimenez F, Holcomb JB
• Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress.
  The Journal of clinical investigation 2010 Chintalgattu V, Ai D, Langley RR, Zhang J, Bankson JA, Shih TL, Reddy AK, Coombes KR, Daher IN, Pati S, Patel SS, Pocius JS, Taffet GE, Buja LM, Entman ML, Khakoo AY
• Intra-hippocampal administration of the VEGF receptor blocker PTK787/ZK222584 impairs long-term memory.
  Brain research 2008 Pati S, Orsi SA, Moore AN, Dash PK
• HIV-1 transgenic rat CD4+ T cells develop decreased CD28 responsiveness and suboptimal Lck tyrosine dephosphorylation following activation.
  Virology 2006 Yadav A, Pati S, Nyugen A, Barabitskaja O, Mondal P, Anderson M, Gallo RC, Huso DL, Reid W
• Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma.
  The Journal of experimental medicine 2006 Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide D, Combs CA, Hall G, Zhang J, Raffeld M, Rogers TB, Stetler-Stevenson W, Frank JA, Reitz M, Finkel T
• Suppression of MIP-1beta transcription in human T cells is regulated by inducible cAMP early repressor (ICER).
  Journal of leukocyte biology 2006 Barabitskaja O, Foulke JS, Pati S, Bodor J, Reitz MS
• Tumorigenesis by human herpesvirus 8 vGPCR is accelerated by human immunodeficiency virus type 1 Tat.
  Journal of virology 2004 Guo HG, Pati S, Sadowska M, Charurat M, Reitz M
• Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat.
  Journal of virology 2003 Pati S, Foulke JS, Barabitskaya O, Kim J, Nair BC, Hone D, Smart J, Feldman RA, Reitz M
• Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma.
  Blood 2002 Pati S, Pelser CB, Dufraine J, Bryant JL, Reitz MS, Weichold FF
• Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis.
  Journal of virology 2001 Pati S, Cavrois M, Guo HG, Foulke JS, Kim J, Feldman RA, Reitz M
• Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation?
  Journal of the National Cancer Institute. Monographs 2001 Samaniego F, Pati S, Karp JE, Prakash O, Bose D
• Urinary proteins with pro-apoptotic and antitumor activity.
  Apoptosis : an international journal on programmed cell death 2000 Pati S, Lee Y, Samaniego F
• HIV-1 protease inhibitor ritonavir modulates susceptibility to apoptosis of uninfected T cells.
  Journal of human virology 1999 Weichold FF, Bryant JL, Pati S, Barabitskaya O, Gallo RC, Reitz MS
• Gain of function mutations in p53.
  Nature genetics 1993 Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C, Levine AJ