Shweta Motiwala, MD, MPH
Associate Professor
Medicine
School of Medicine
I am an Advanced Heart Failure and Transplant cardiologist, and the Director of Heart Failure Disease Management at UCSF. I have clinical expertise in evaluating and treating patients across the spectrum of heart failure disease severity, including those who require mechanical circulatory support or heart transplantation.
Show full bio (100 words) Hide full bio
I have a particular interest in developing chronic disease management programs to improve clinical outcomes and quality of life in patients with heart failure. These include initiatives to expand the use of remote monitoring technologies and platforms, to optimize the application of guideline-directed medical and device therapy, and to improve access to care and transitions of care.
My research interests include the use of biomarkers in understanding response to therapy and outcomes in heart failure, evaluation of novel remote monitoring and therapeutic devices, and approaches to improving delivery of care to broad patient populations.
Awards
Show all (5) Hide
- Gerald E. Altman, MD and Harriet Altman Annual Cardiology Fellow Award (Clinical Excellence), Beth Israel Deaconess Medical Center, 2016
- Dennis and Marilyn Barry Fellowship in Cardiovascular Medicine (Research), Massachusetts General Hospital, 2012-2013
- AMWA Glasgow-Rubin Award (Academic Achievement), New York University School of Medicine, 2009
- Alpha Omega Alpha Honor Society, New York University School of Medicine, 2008
- Doris Duke Clinical Research Fellowship, Doris Duke Charitable Foundation, 2007-2008
Education & Training
Show all (6) Hide
- MPH Clinical Effectiveness Harvard T.H. Chan School of Public Health 2019
- Fellowship Advanced Heart Failure and Transplant Cardiology Brigham and Women's Hospital 2017
- Fellowship Cardiovascular Disease Beth Israel Deaconess Medical Center 2016
- Residency Internal Medicine Massachusetts General Hospital 2012
- MD Medicine New York University School of Medicine 2009
- AB History and Science Harvard College 2004
Publications (39)
Top publication keywords:
Cardiovascular DiseasesVentricular Dysfunction, LeftNatriuretic Peptide, BrainVentricular Function, LeftAcute Coronary SyndromeInsulin-Like Growth Factor Binding ProteinsVentricular RemodelingVitamin D DeficiencyGalectin 3Bacterial ToxinsVitamin DBiomarkersHeart FailureStroke VolumeTroponin I
-
2024 ACC Expert Consensus Decision Pathway for Treatment of Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee.
Journal of the American College of Cardiology 2024 Maddox TM, Januzzi JL, Allen LA, Breathett K, Brouse S, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Lindenfeld J, Masoudi FA, Motiwala SR, Oliveros E, Walsh MN, Wasserman A, Yancy CW, Youmans QR -
Risk Stratification in Advanced Heart Failure: Can Simple Hemodynamic Indices Replace Comprehensive CPET?
JACC. Heart failure 2023 Motiwala SR, Nayor M -
Induction immunosuppression and post-transplant diabetes mellitus: a propensity-matched cohort study.
Frontiers in endocrinology 2023 Gupta SK, Mostofsky E, Motiwala SR, Hage A, Mittleman MA -
Outcomes With Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Suspected Acute Myocarditis: 10-Year Experience From the Extracorporeal Life Support Organization Registry.
Circulation. Heart failure 2023 Nunez JI, Grandin EW, Reyes-Castro T, Sabe M, Quintero P, Motiwala S, Fleming LM, Sriwattanakomen R, Ho JE, Kennedy K, Tonna JE, Garan AR -
Cardiogenic shock related cardiovascular disease mortality trends in US population: Heart failure vs. acute myocardial infarction as contributing causes.
International journal of cardiology 2022 Ghajar A, Ordonez CP, Philips B, Pinzon PQ, Fleming LM, Motiwala SR, Sriwattanakomen R, Ho JE, Grandin EW, Sabe M, Garan AR
Show all (34 more) Hide
-
Post-transplant mortality and graft failure after induction immunosuppression among Black heart transplant recipients in the United States.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2022 Salia S, Mostofsky E, Gupta S, Lehman L, Barrera FJ, Liou L, Motiwala SR, Mittleman MA -
2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee.
Journal of the American College of Cardiology 2021 Writing Committee, Maddox TM, Januzzi JL, Allen LA, Breathett K, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Lindenfeld J, Masoudi FA, Motiwala SR, Oliveros E, Patterson JH, Walsh MN, Wasserman A, … -
From Proteomics to Therapeutics: Sex Differences in Cardiovascular Disease Risk Do Matter.
Journal of the American College of Cardiology 2019 Motiwala SR -
A clinical and proteomics approach to predict the presence of obstructive peripheral arterial disease: From the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) Study.
Clinical cardiology 2018 McCarthy CP, Ibrahim NE, van Kimmenade RRJ, Gaggin HK, Simon ML, Gandhi P, Kelly N, Motiwala SR, Mukai R, Magaret CA, Barnes G, Rhyne RF, Garasic JM, Januzzi JL -
Single-Molecule Counting of High-Sensitivity Troponin I in Patients Referred for Diagnostic Angiography: Results From the CASABLANCA (Catheter Sampled Blood Archive in Cardiovascular Diseases) Study.
Journal of the American Heart Association 2018 McCarthy CP, Ibrahim NE, Lyass A, Li Y, Gaggin HK, Simon ML, Mukai R, Gandhi P, Kelly N, Motiwala SR, van Kimmenade RRJ, Massaro JM, D'Agostino RB, Januzzi JL -
Predicting new-onset HF in patients undergoing coronary or peripheral angiography: results from the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) study.
ESC heart failure 2018 Ibrahim NE, Lyass A, Gaggin HK, Liu Y, van Kimmenade RRJ, Motiwala SR, Kelly NP, Gandhi PU, Simon ML, Belcher AM, Harisiades JE, Massaro JM, D'Agostino RB, Januzzi JL -
2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Task Force on Expert Consensus Decision Pathways.
Journal of the American College of Cardiology 2017 Yancy CW, Januzzi JL, Allen LA, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Jessup M, Lindenfeld J, Maddox TM, Masoudi FA, Motiwala SR, Patterson JH, Walsh MN, Wasserman A -
Systematic Evaluation of Endothelin 1 Measurement Relative to Traditional and Modern Biomarkers for Clinical Assessment and Prognosis in Patients With Chronic Systolic Heart Failure: Serial Measurement and Multimarker Testing.
American journal of clinical pathology 2017 Gaggin HK, Truong QA, Gandhi PU, Motiwala SR, Belcher AM, Weiner RB, Baggish AL, Januzzi JL -
Usefulness of Multiple Biomarkers for Predicting Incident Major Adverse Cardiac Events in Patients Who Underwent Diagnostic Coronary Angiography (from the Catheter Sampled Blood Archive in Cardiovascular Diseases [CASABLANCA] Study).
The American journal of cardiology 2017 McCarthy CP, van Kimmenade RRJ, Gaggin HK, Simon ML, Ibrahim NE, Gandhi P, Kelly N, Motiwala SR, Belcher AM, Harisiades J, Magaret CA, Rhyne RF, Januzzi JL -
Associations Between Psychological Constructs and Cardiac Biomarkers After Acute Coronary Syndrome.
Psychosomatic medicine 2017 Celano CM, Beale EE, Beach SR, Belcher AM, Suarez L, Motiwala SR, Gandhi PU, Gaggin H, Januzzi JL, Healy BC, Huffman JC -
A Clinical and Biomarker Scoring System to Predict the Presence of Obstructive Coronary Artery Disease.
Journal of the American College of Cardiology 2017 Ibrahim NE, Januzzi JL, Magaret CA, Gaggin HK, Rhyne RF, Gandhi PU, Kelly N, Simon ML, Motiwala SR, Belcher AM, van Kimmenade RRJ -
Native T1 value in the remote myocardium is independently associated with left ventricular dysfunction in patients with prior myocardial infarction.
Journal of magnetic resonance imaging : JMRI 2017 Nakamori S, Alakbarli J, Bellm S, Motiwala SR, Addae G, Manning WJ, Nezafat R -
Incident Type 2 Myocardial Infarction in a Cohort of Patients Undergoing Coronary or Peripheral Arterial Angiography.
Circulation 2016 Gaggin HK, Liu Y, Lyass A, van Kimmenade RR, Motiwala SR, Kelly NP, Mallick A, Gandhi PU, Ibrahim NE, Simon ML, Bhardwaj A, Belcher AM, Harisiades JE, Massaro JM, D'Agostino RB, Januzzi JL -
Biomarkers to Predict Reverse Remodeling and Myocardial Recovery in Heart Failure.
Current heart failure reports 2016 Motiwala SR, Gaggin HK -
Effects of Optimism and Gratitude on Physical Activity, Biomarkers, and Readmissions After an Acute Coronary Syndrome: The Gratitude Research in Acute Coronary Events Study.
Circulation. Cardiovascular quality and outcomes 2015 Huffman JC, Beale EE, Celano CM, Beach SR, Belcher AM, Moore SV, Suarez L, Motiwala SR, Gandhi PU, Gaggin HK, Januzzi JL -
Design and baseline data from the Gratitude Research in Acute Coronary Events (GRACE) study.
Contemporary clinical trials 2015 Huffman JC, Beale EE, Beach SR, Celano CM, Belcher AM, Moore SV, Suarez L, Gandhi PU, Motiwala SR, Gaggin H, Januzzi JL -
Assessment of mitral valve disease: a review of imaging modalities.
Current treatment options in cardiovascular medicine 2015 Motiwala SR, Delling FN -
Concentrations of highly sensitive cardiac troponin-I predict poor cardiovascular outcomes and adverse remodeling in chronic heart failure.
Journal of cardiovascular translational research 2015 Motiwala SR, Gaggin HK, Gandhi PU, Belcher A, Weiner RB, Baggish AL, Szymonifka J, Januzzi JL -
Comparison between admission natriuretic peptides, NGAL and sST2 testing for the prediction of worsening renal function in patients with acutely decompensated heart failure.
Clinical chemistry and laboratory medicine 2015 De Berardinis B, Gaggin HK, Magrini L, Belcher A, Zancla B, Femia A, Simon M, Motiwala S, Bhardwaj A, Parry BA, Nagurney JT, Coudriou C, Legrand M, Sadoune M, Di Somma S, Januzzi JL, Global Research … -
Galectin-3 and mineralocorticoid receptor antagonist use in patients with chronic heart failure due to left ventricular systolic dysfunction.
American heart journal 2015 Gandhi PU, Motiwala SR, Belcher AM, Gaggin HK, Weiner RB, Baggish AL, Fiuzat M, Brunner-La Rocca HP, Januzzi JL -
Evidence of uncoupling between renal dysfunction and injury in cardiorenal syndrome: insights from the BIONICS study.
PloS one 2014 Legrand M, De Berardinis B, Gaggin HK, Magrini L, Belcher A, Zancla B, Femia A, Simon M, Motiwala S, Sambhare R, Di Somma S, Mebazaa A, Vaidya VS, Januzzi JL, Global Research on Acute Conditions Team… -
ST2 pathogenetic profile in ambulatory heart failure patients.
Journal of cardiac failure 2014 Bayes-Genis A, Januzzi JL, Gaggin HK, de Antonio M, Motiwala SR, Zamora E, Galán A, Domingo M, Urrutia A, Lupón J -
Characterization and prediction of adverse events from intensive chronic heart failure management and effect on quality of life: results from the pro-B-type natriuretic peptide outpatient-tailored chronic heart failure therapy (PROTECT) study.
Journal of cardiac failure 2014 Gandhi PU, Szymonifka J, Motiwala SR, Belcher AM, Januzzi JL, Gaggin HK -
Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function?
The American journal of cardiology 2014 Gandhi PU, Gaggin HK, Sheftel AD, Belcher AM, Weiner RB, Baggish AL, Motiwala SR, Liu PP, Januzzi JL -
Head-to-head comparison of serial soluble ST2, growth differentiation factor-15, and highly-sensitive troponin T measurements in patients with chronic heart failure.
JACC. Heart failure 2014 Gaggin HK, Szymonifka J, Bhardwaj A, Belcher A, De Berardinis B, Motiwala S, Wang TJ, Januzzi JL -
Measurement of novel biomarkers to predict chronic heart failure outcomes and left ventricular remodeling.
Journal of cardiovascular translational research 2013 Motiwala SR, Szymonifka J, Belcher A, Weiner RB, Baggish AL, Gaggin HK, Bhardwaj A, Januzzi JL -
Biomarkers in ACS and heart failure: should men and women be interpreted differently?
Clinical chemistry 2013 Motiwala SR, Sarma A, Januzzi JL, O'Donoghue ML -
Soluble concentrations of the interleukin receptor family member ST2 and β-blocker therapy in chronic heart failure.
Circulation. Heart failure 2013 Gaggin HK, Motiwala S, Bhardwaj A, Parks KA, Januzzi JL -
Serial measurement of galectin-3 in patients with chronic heart failure: results from the ProBNP Outpatient Tailored Chronic Heart Failure Therapy (PROTECT) study.
European journal of heart failure 2013 Motiwala SR, Szymonifka J, Belcher A, Weiner RB, Baggish AL, Sluss P, Gaggin HK, Bhardwaj A, Januzzi JL -
Using biomarkers to "guide" heart failure management: current perspectives and future directions.
Cardiology in review 2013 Motiwala SR, Januzzi JL -
Depression and cardiac disease: epidemiology, mechanisms, and diagnosis.
Cardiovascular psychiatry and neurology 2013 Huffman JC, Celano CM, Beach SR, Motiwala SR, Januzzi JL -
The role of natriuretic peptides as biomarkers for guiding the management of chronic heart failure.
Clinical pharmacology and therapeutics 2012 Motiwala SR, Januzzi JL -
Vitamin D and cardiovascular risk.
Current hypertension reports 2012 Motiwala SR, Wang TJ -
Vitamin D and cardiovascular disease.
Current opinion in nephrology and hypertension 2011 Motiwala SR, Wang TJ