Shu Liu, PhD
Specialist
Surgery
School of Medicine
Websites
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Publications (7)
Top publication keywords:
Cyclin D1Molecular Docking SimulationNational Cancer Institute (U.S.)Casein Kinase IIStructure-Activity RelationshipCyclinsProtein Kinase InhibitorsMitogen-Activated Protein Kinase 3Cyclin-Dependent Kinase 2Cyclin-Dependent KinasesBiological ProductsCyclin-Dependent Kinase Inhibitor p27Mitogen-Activated Protein Kinase 1CoumestrolStructural Homology, Protein
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Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.
Oncotarget 2015 You B, Yang YL, Xu Z, Dai Y, Liu S, Mao JH, Tetsu O, Li H, Jablons DM, You L -
Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activity.
Journal of medicinal chemistry 2014 Premnath PN, Craig SN, Liu S, Anderson EL, Grigoroudis AI, Kontopidis G, Perkins TL, Wyatt MD, Pittman DL, McInnes C -
Fragment based discovery of arginine isosteres through REPLACE: towards non-ATP competitive CDK inhibitors.
Bioorganic & medicinal chemistry 2013 Premnath PN, Liu S, Perkins T, Abbott J, Anderson E, McInnes C -
Coumestrol from the national cancer Institute's natural product library is a novel inhibitor of protein kinase CK2.
BMC pharmacology & toxicology 2013 Liu S, Hsieh D, Yang YL, Xu Z, Peto C, Jablons DM, You L -
J. Med. Chemistry
Optimization of Non-ATP Competitive CDK/Cyclin Groove Inhibitors through REPLACE-Mediated Fragment Assembly 2013 Shu Liu, Padmavathy Nandha Premnath, Joshua K. Bolger, Tracy L. Perkins, Lindsay O. Kirkland, George Kontopidis, and Campbell McInnes -
Structural and functional analysis of cyclin D1 reveals p27 and substrate inhibitor binding requirements.
ACS chemical biology 2010 Liu S, Bolger JK, Kirkland LO, Premnath PN, McInnes C -
Transdermal protein delivery by a coadministered peptide identified via phage display.
Nature biotechnology 2006 Chen Y, Shen Y, Guo X, Zhang C, Yang W, Ma M, Liu S, Zhang M, Wen LP