Shravani Mukherjee, PhD, MSc
Associate Researcher
Human Genetics
School of Medicine

Interested in single cell biology of complex diseases. Leading translational research and functional genomics studies with both academic and industrial experience in cell based disease models, cell-engineering, single cell omics, high-throughput screening and biomarker assay designs.

Awards

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• Single Cell Atlas Pilot Grant, Chan Zuckerberg Biohub, Stanford University, 2018-2020
• CSIR-SRF, CSIR - Council of Scientific & Industrial Research, India, 2013-2016
• GATE, Ministry of Education, Gov. of India, 2010

Education & Training

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• Scientist High-throughput Cell Engineering Chan Zuckerberg Biohub 11/2022
• Postdoc Cell Biology Stanford University 08/2020
• PhD Biology CSIR Institute of Genomics & Integrative Biology 09/2016
• MSc Molecular Biology & Genetics Presidency College, University of Calcutta 07/2009
• BSc Zoology (H) Serampore College, University of Calcutta 07/2007

Websites

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• Linkedin (linkedin.com)
• Google Scholar (scholar.google.co.in)

Publications (8)

Top publication keywords:
Cellular Reprogrammingrho GTP-Binding ProteinsKu AutoantigenCartilageAtlases as TopicOrgan SpecificityCellsRNA SplicingSingle-Cell AnalysisTranscriptomeOsteoarthritisCheirogaleidaeCellular SenescenceCell-Free Nucleic AcidsRejuvenation

• The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.
  Science (New York, N.Y.) 2022 Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, …
• Cell types of origin of the cell-free transcriptome.
  Nature biotechnology 2022 Vorperian SK, Moufarrej MN, Tabula Sapiens Consortium, Quake SR
• RNA splicing programs define tissue compartments and cell types at single-cell resolution.
  eLife 2021 Olivieri JE, Dehghannasiri R, Wang PL, Jang S, de Morree A, Tan SY, Ming J, Ruohao Wu A, Tabula Sapiens Consortium, Quake SR, Krasnow MA, Salzman J
• Noncanonical role for Ku70/80 in the prevention of allergic airway inflammation via maintenance of airway epithelial cell organelle homeostasis.
  American journal of physiology. Lung cellular and molecular physiology 2020 Rehman R, Vijayakumar VE, Jaiswal A, Jain V, Mukherjee S, Vellarikkal SK, Dieffenbach PB, Fredenburgh LE, Prakash YS, Ghosh B, Agrawal A, Mabalirajan U
• Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells.
  Nature communications 2020 Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, Tran CM, Chu CR, Horvath S, Qi LS, Bhutani N, Rando TA, Sebastiano V
• Single-cell mass cytometry reveals cross-talk between inflammation-dampening and inflammation-amplifying cells in osteoarthritic cartilage.
  Science advances 2020 Grandi FC, Baskar R, Smeriglio P, Murkherjee S, Indelli PF, Amanatullah DF, Goodman S, Chu C, Bendall S, Bhutani N
• Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy.
  The EMBO journal 2014 Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari BK, Jha KA, Barhanpurkar AP, Wani MR, Roy SS, Mabalirajan U, Ghosh B, Agrawal A
• Computational classification of mitochondrial shapes reflects stress and redox state.
  Cell death & disease 2013 Ahmad T, Aggarwal K, Pattnaik B, Mukherjee S, Sethi T, Tiwari BK, Kumar M, Micheal A, Mabalirajan U, Ghosh B, Sinha Roy S, Agrawal A