Seul Yeon, PhD
Postdoctoral Scholar
Cardiovascular Research Inst
School of Medicine

Publications (13)

Top publication keywords:
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineCalcium Channels, N-TypeNerve Tissue ProteinsNeurofibromin 1Monoamine Oxidase InhibitorsMonoamine OxidaseD-Amino-Acid OxidaseMacrolidesMicrococcusParkinson DiseaseAcetamidesBenzene DerivativesIntercellular Signaling Peptides and ProteinsBacillus subtilisSulfones

• Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis.
  Journal of medicinal chemistry 2022 Park SJ, Yeon SK, Kim Y, Kim HJ, Kim S, Kim J, Choi JW, Kim B, Lee EH, Kim R, Seo SH, Lee J, Kim JW, Lee HY, Hwang H, Bahn YS, Cheong E, Park JH, Park KD
• Optimization and Evaluation of Novel Antifungal Agents for the Treatment of Fungal Infection.
  Journal of medicinal chemistry 2021 Choi JW, Lee KT, Kim S, Lee YR, Kim HJ, Seo KJ, Lee MH, Yeon SK, Jang BK, Park SJ, Kim HJ, Park JH, Kim D, Lee DG, Cheong E, Lee JS, Bahn YS, Park KD
• Modular Approaches to Lankacidin Antibiotics.
  Journal of the American Chemical Society 2020 Cai L, Yao Y, Yeon SK, Seiple IB
• Modulation of CRMP2 via (S)-Lacosamide shows therapeutic promise but is ultimately ineffective in a mouse model of CLN6-Batten disease.
  Neuronal signaling 2019 White KA, Cain JT, Magee H, Yeon SK, Park KD, Khanna R, Weimer JM
• Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer's disease.
  Science advances 2019 Park JH, Ju YH, Choi JW, Song HJ, Jang BK, Woo J, Chun H, Kim HJ, Shin SJ, Yarishkin O, Jo S, Park M, Yeon SK, Kim S, Kim J, Nam MH, Londhe AM, Kim J, Cho SJ, Cho S, Lee C, Hwang SY, Kim SW, Oh SJ, …

Show all (8 more) Hide

• CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide.
  Pain 2017 Moutal A, Yang X, Li W, Gilbraith KB, Luo S, Cai S, François-Moutal L, Chew LA, Yeon SK, Bellampalli SS, Qu C, Xie JY, Ibrahim MM, Khanna M, Park KD, Porreca F, Khanna R
• Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.
  Bioorganic & medicinal chemistry 2017 Yeon SK, Choi JW, Park JH, Lee YR, Kim HJ, Shin SJ, Jang BK, Kim S, Bahn YS, Han G, Lee YS, Pae AN, Park KD
• CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation.
  Molecular neurobiology 2017 Moutal A, Villa LS, Yeon SK, Householder KT, Park KD, Sirianni RW, Khanna R
• (S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.
  Pain 2016 Moutal A, Chew LA, Yang X, Wang Y, Yeon SK, Telemi E, Meroueh S, Park KD, Shrinivasan R, Gilbraith KB, Qu C, Xie JY, Patwardhan A, Vanderah TW, Khanna M, Porreca F, Khanna R
• Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica.
  ChemMedChem 2016 Ju EJ, Yeon SK, Park JH, Cheon SY, Choi JW, Ha T, Jang BK, Kim S, Kang YG, Hwang H, Cho SJ, Cheong E, Bahn YS, Pae AN, Kim SM, Park KD
• Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors.
  Bioorganic & medicinal chemistry 2015 Choi JW, Jang BK, Cho NC, Park JH, Yeon SK, Ju EJ, Lee YS, Han G, Pae AN, Kim DJ, Park KD
• (S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5.
  Molecular neurobiology 2015 Moutal A, François-Moutal L, Perez-Miller S, Cottier K, Chew LA, Yeon SK, Dai J, Park KD, Khanna M, Khanna R
• Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy.
  Journal of medicinal chemistry 2014 Woo SY, Kim JH, Moon MK, Han SH, Yeon SK, Choi JW, Jang BK, Song HJ, Kang YG, Kim JW, Lee J, Kim DJ, Hwang O, Park KD